A2_MetyuMelkonyan.rmd

• Bioconductor (Durinck et al. (2009))
• R language (R Core Team (2022))
• Article (Adams et al. (2019))
• Rmarkdown (Allaire et al. (2021))
• edgeR (Robinson, DJ, and Smyth (2010))
• GEOquery (Davis and Meltzer (2007))
• SHH (Magliano et al. (2006))
• Limma (Ritchie et al. (2015))
• ComplexHeatMap (Gu (2022))
• Circlize (Gu et al. (2014))

Installing Dependencies

if (!requireNamespace("BiocManager", quietly = TRUE)){
  install.packages("BiocManager")}
if (!requireNamespace("edgeR", quietly = TRUE)){
  BiocManager::install("edgeR")}
if (!requireNamespace("GEOquery", quietly = TRUE)){
  BiocManager::install("GEOquery")}
if (!requireNamespace("ComplexHeatmap", quietly = TRUE)){
  BiocManager::install("ComplexHeatmap")}
if (!requireNamespace("limma", quietly = TRUE)){
  BiocManager::install("limma")}
if (!requireNamespace("ExpressionSet", quietly = TRUE)){
  BiocManager::install("ExpressionSet")}

## Warning: package 'ExpressionSet' is not available for Bioconductor version '3.16'
## 
## A version of this package for your version of R might be available elsewhere,
## see the ideas at
## https://cran.r-project.org/doc/manuals/r-patched/R-admin.html#Installing-packages

if  (!requireNamespace("circlize", quietly = TRUE)){
  BiocManager::install("circlize")}
if (!requireNamespace("gprofiler2", quietly = TRUE))
    BiocManager::install("gprofiler2")
if (!requireNamespace("kableExtra", quietly = TRUE))
    BiocManager::install("kableExtra")

## Warning in !is.null(rmarkdown::metadata$output) && rmarkdown::metadata$output
## %in% : 'length(x) = 2 > 1' in coercion to 'logical(1)'

if (!requireNamespace("plotly", quietly = TRUE))
    BiocManager::install("plotly")
if (!requireNamespace("dplyr", quietly = TRUE))
    BiocManager::install("dplyr")
library(dplyr)
library(plotly)

Part 1: Loading the normalized gene data

The normalized data has already been written into a text file by the previous Assignment 1. For better assessment, I have indicated it on the file uploaded.

normalized_count_data <- read.table(file=file.path(getwd(), "normalized_counts_annotated")
, header = TRUE, stringsAsFactors = FALSE, check.names = FALSE )

knitr::kable(normalized_count_data[1:10,1:7], type="pipe")

hgnc_symbol	YRE1A	YRE1B	YRE2A	YRG1A	YRG1B	YRG2B
A4GALT	4.345648	3.111477	2.408097	5.369569	6.397003	6.796014
AAAS	19.317681	22.327817	21.792253	18.384756	17.419577	17.311220
AACS	32.913059	24.534108	24.466495	23.731644	17.621289	17.428989
AADACP1	2.418554	4.507231	3.916687	13.734990	14.270060	14.143042
AADAT	4.058510	3.995899	3.647402	4.637361	4.052613	3.678086
AAED1	14.351471	11.913866	12.242066	12.711562	8.425186	7.790737
AAGAB	36.922469	35.816951	39.338927	40.358329	31.836730	30.961949
AAK1	1.531217	1.364910	1.534162	2.165459	2.677295	2.667404
AAMDC	46.807715	44.246410	48.924065	66.090858	49.702345	44.178113
AAMP	82.175802	88.352333	93.832788	76.203567	81.078221	82.443384

Part 2: Defining Portions of the Heatmap Matrix

I am defining the elements of the normalized data matrix which I will be using for the heatmap later.

Part 3: Creating Heatmap

The heatmap uses different colors for the expression data. The heatmap has many genes clustered based on their expression at different levels such as control (EA1,EA2,EB1) or the cells treated with GLI2 (G1A,G2A,G1B).

if(min(heatmap_matrix) == 0){
   heatmap_col = circlize::colorRamp2(c( 0, max(heatmap_matrix)),
                           c("white", "purple"))
} else {
  heatmap_col = circlize::colorRamp2(c(min(heatmap_matrix), 0,
         max(heatmap_matrix)), c("darkgreen", "white", "purple"))
}
first_heatmap <- ComplexHeatmap::Heatmap(as.matrix(heatmap_matrix),
     show_row_dend = TRUE, show_column_dend = TRUE,
     col=heatmap_col, show_column_names = TRUE,
     show_row_names = FALSE, show_heatmap_legend = TRUE)
first_heatmap

### Part 4: SPP1 EMT Genes-Conclusion justification
SPP1 is an EMT genes It shows higher expression when treated with GLI2 compare to empty vector control cells (EV). This has been also proved by the authors. However, indicating this again would strengthen the hypothesis corresponding to Dox treated cells having GLI2 vector show higher EMT gene expression as opposed to controls having empty vector showing less expression of the genes.

GLI2_treatment_samples <- grep(colnames(normalized_count_data),pattern = "\\G")
EV_tratment_samples <- grep(colnames(normalized_count_data),pattern = "\\E")
gene_of_interest <- which(normalized_count_data$Gene_symbol == "SPP1")

YAPC_GLI2_samples <- t(normalized_count_data[gene_of_interest,5:7])
colnames(YAPC_GLI2_samples) <- c("GLI2_vector_cells")

YAPC_EV_samples <- t(normalized_count_data[gene_of_interest,2:4])
colnames(YAPC_EV_samples) <- c("Empty_Vector_cells")

YAPC_GLI2_samples

##       GLI2_vector_cells
## YRG1A          321.9614
## YRG1B          607.5096
## YRG2B          580.2982

YAPC_EV_samples

##       Empty_Vector_cells
## YRE1A           1.307170
## YRE1B           1.616595
## YRE2A           1.752119

Part 5: T-test between EV and GLI2

GLI2 treated cells are different in terms of their expression from the empty vector cells. P value (0.03135) < 0.05. Indeed this shows there is significant difference. However, this requires to see if GLI2 treatments show difference among one another so the control cells.

t.test(x=t(YAPC_GLI2_samples), y=t(YAPC_EV_samples))

## 
##  Welch Two Sample t-test
## 
## data:  t(YAPC_GLI2_samples) and t(YAPC_EV_samples)
## t = 5.5139, df = 2, p-value = 0.03135
## alternative hypothesis: true difference in means is not equal to 0
## 95 percent confidence interval:
##  110.2125 893.1831
## sample estimates:
##  mean of x  mean of y 
## 503.256412   1.558628

PART 6: MDS Plot for Sample Clustering

The MDS plot allowed to visualize the difference within the different cell types Earlier examples of MDS plot showed similar results. I hypothesize that GLI2 expression is higher than control cell’s expression levels due to DOX induction of EMT genes. In general I have observed Gli2 cells to be less clustered, due to higher differential expression among GLI2 cells.

limma::plotMDS(heatmap_matrix,col=c(rep("darkgreen",3), rep("blue",3)))

### Part 7: Model Building of GLI2 expression status The model I am building is based upon GLI2 expression status of genes that are showing higher expression with significant indications of the differential expression.

samples <- data.frame(lapply(colnames(normalized_count_data)[2:7],
           FUN=function(x){unlist(strsplit(x, split = "[0-9]"))[c(1)]}))

colnames(samples) <- colnames(colnames(normalized_count_data)[2:7])
rownames(samples) <- c("Treatments")
samples <- data.frame(t(samples))
knitr::kable(samples, type = "pipe") 

Treatments
YRE
YRE
YRE
YRG
YRG
YRG

YRG_model <- model.matrix( ~ samples$Treatments)
knitr::kable(YRG_model[1:6,], type = "pipe")

(Intercept)	samples$TreatmentsYRG
1	0
1	0
1	0
1	1
1	1
1	1

Part 8: Model Fitting and Differential Expression Calculation

The differential expression data matrix corresponding to gene symbols were merged with the matrix that has the fitted model. The Benjamin-hochberg correction method was applied to adjust the expression data.

expressionMatrix <- as.matrix(normalized_count_data[,2:7])
rownames(expressionMatrix) <- normalized_count_data$Gene_symbol
colnames(expressionMatrix) <- colnames(normalized_count_data)[2:7]
set_expression_matrix <- Biobase::ExpressionSet(assayData = expressionMatrix)

fit <- limma::lmFit(set_expression_matrix, YRG_model)

fit_Bayes <- limma::eBayes(fit, trend = TRUE)

BH_method_fit <- limma::topTable(fit_Bayes,
                   coef = ncol(YRG_model),
                   adjust.method = "BH",
                   number = nrow(expressionMatrix))

merged_hits <- merge(normalized_count_data$Gene_symbol,
                     BH_method_fit,
                     by.y=0,by.x=1,
                     all.y=TRUE)

merged_hits <- merged_hits[order(merged_hits$P.Value),]
colnames(merged_hits) <- c("Gene_symbol","logFC", "AveExpr", "t",
                           "P.Value","adj.P.Val", "B")
rownames(merged_hits) <- 1:nrow(merged_hits)

knitr::kable(merged_hits[1:10,1:7], type = "pipe", row.names = FALSE,)

Gene_symbol	logFC	AveExpr	t	P.Value	adj.P.Val	B
S100A2	192.67873	105.164286	63.79569	0e+00	0.0000245	1.820600
SSFA2	76.45805	75.591839	45.17567	0e+00	0.0000789	1.781362
NT5E	86.27685	123.407858	42.93449	0e+00	0.0000789	1.773004
S100A13	132.80964	179.285328	37.98876	0e+00	0.0001191	1.749192
TRIB2	51.68968	38.062060	35.69100	1e-07	0.0001361	1.734718
HEG1	-13.44713	8.317468	-31.24508	1e-07	0.0002423	1.697467
NTN4	35.83705	33.048568	28.42566	2e-07	0.0003561	1.664696
UCP2	80.78518	94.331418	26.66241	3e-07	0.0004488	1.638993
PLLP	-31.42241	35.188668	-25.42904	4e-07	0.0004683	1.617932
UNC5B	19.59576	12.041479	24.78963	5e-07	0.0004683	1.605831

Part 9: P-value Assessment

The p-value was adjusted to have more stringent results. Normally significant p-value is set to 0.05. However, I wanted to be more stringent on my results and indicate the specific EMT genes. Probable genes are 741. However, there are 27 genes that have significant potential to be an EMT gene.

length(which(merged_hits$P.Value < 0.0005))

## [1] 741

length(which(merged_hits$adj.P.Val < 0.0005))

## [1] 27

Part 10: Model Visualization

This part of this assignment aims to detect SPP1’s role on how GLI2 cells are more differently expressed and do have higher difference than the control cells. It is evident that, with more stringent p-value, the significant portion (741) of about 11500 genes are showing features of EMT genes

model_pvalues <- data.frame(Gene_symbol = merged_hits$Gene_symbol, 
pvalue = merged_hits$P.Value)

model_pvalues$color <- "black"
model_pvalues$color[model_pvalues$pvalue < 0.0005] <- "orange"
    
SPP1 <- normalized_count_data$Gene_symbol[which(normalized_count_data$Gene_symbol == "SPP1")]
model_pvalues$color[model_pvalues$Gene_symbol== SPP1] <- "red"

plot(model_pvalues$pvalue,
     col = model_pvalues$color,
     xlab = "Number of Genes within the Dataset",
     ylab ="P-value",
     main="P value distribution of EMT Genes")

points(model_pvalues[which(model_pvalues$Gene_symbol == "SPP1"), 1:2],
       pch = 20, col="red", cex=1.5)
legend(0, 1, legend=c("SPP1"), fill=c("red"))

### Part 11: Clustered Heatmap with More Stringent Values With more stringent gene size I was able to see cleaner difference between GLI2 and the control cells. The clustered genes are the symmetric each other across the diagonals. The high expression showing genes on the GLI2’s side is lower on the EV’ side. Top hits are assessed on the stringent p-value of 0.0005. The difference between the first and the latest heatmap shows there is significant difference in terms of gene expression whose expression is represented for each respective Treatments

top_hits <- merged_hits$Gene_symbol[merged_hits$P.Value < 0.0005]
heatmap_matrix_tophits <- t(scale(t(heatmap_matrix[which(rownames(heatmap_matrix) 
                       %in% top_hits),])))

if(min(heatmap_matrix_tophits) == 0){
heatmap_col = circlize::colorRamp2(c( 0, max(heatmap_matrix_tophits)), 
                                   c( "white", "purple"))
} else{
heatmap_col = circlize::colorRamp2(c(min(heatmap_matrix_tophits), 0,
     max(heatmap_matrix_tophits)), c("darkgreen", "white", "purple"))
}
latest_heatmap <- ComplexHeatmap::Heatmap(as.matrix(heatmap_matrix_tophits),
show_row_dend = TRUE, show_column_dend = TRUE, col=heatmap_col,
show_column_names = TRUE, show_row_names = FALSE, show_heatmap_legend = TRUE)
latest_heatmap

first_heatmap

### Part 12: Dataset Filtering and Data Extracting The previously extracted GSE131222 data from gene omnibus expression (GEO) is extracted separately. The low count portions of the data filtered and a new matrix was created.

data = GEOquery::getGEOSuppFiles("GSE131222")
datanames = rownames(data)

GLI2_exp =read.delim(datanames[1],header=TRUE,check.names = FALSE)

count_per_ms = edgeR::cpm(GLI2_exp[,3:8])
rownames(count_per_ms) <- GLI2_exp[,2]

rows_filtered = rowSums(count_per_ms >1) >= 6
GLI2_exp_filtered = GLI2_exp[rows_filtered,]

filtered_GLI2_matrix <- as.matrix(GLI2_exp_filtered[,3:8])
rownames(filtered_GLI2_matrix) <- GLI2_exp_filtered$gene
head(GLI2_exp_filtered)[1:8]

##         gene                locus     YRE1A     YRE1B     YRE2A     YRG1A
## 7  LINC01128   chr1:762970-794826   3.65922   3.95950   4.17393   3.89816
## 9     KLHL17   chr1:895966-901099   8.94838  10.89430  11.20550   6.99464
## 10   PLEKHN1   chr1:901876-910484   4.90645   5.28867   5.02146   4.31839
## 11     ISG15   chr1:948846-949919 322.87300 251.30200 287.47100 328.22400
## 12      AGRN   chr1:955502-991499 198.02100 221.32500 221.63500 163.25300
## 18   B3GALT6 chr1:1167628-1170420  10.17300  12.26130  12.14880  11.34150
##        YRG1B     YRG2B
## 7    3.33866   3.57704
## 9   10.45200  10.27520
## 10   4.29991   4.14435
## 11 562.14200 586.97600
## 12 214.04600 219.62400
## 18  12.56020  11.78190

Part 13: Grouping Based on the Cell Types

The similar grouping was done previously. However this time dispersion values, normalization factors and differential expression model fitting is applied to the samples of GLI2 treatments.

grouped_treatments <- data.frame(lapply(colnames(GLI2_exp_filtered)[3:8],
                FUN=function(x){unlist(strsplit(x, split = "[0-9]"))[c(1)]}))
colnames(grouped_treatments) <- colnames(GLI2_exp)[3:8]
rownames(grouped_treatments) <- c("cell_type")
grouped_treatments_normalized <- data.frame(t(grouped_treatments))
d = edgeR::DGEList(counts=filtered_GLI2_matrix, group = grouped_treatments_normalized$cell_type)

model_design_celltypes <- model.matrix(~grouped_treatments_normalized$cell_type+0)
d <- edgeR::estimateDisp(d, model_design_celltypes)
d <- edgeR::calcNormFactors(d)
fit <- edgeR::glmQLFit(d, model_design_celltypes)
qlf_test.GLI2vsEV <- edgeR::glmQLFTest(fit, coef = "grouped_treatments_normalized$cell_typeYRG")

Part 14: Significant Results within the Fitted Model

With more stringent p-value I was able to assess the critical threshold for the expression threshold. I set the p-value as 0.0005. I decided to put it by adjusting and observing any difference. The difference between p-value 0.005 and p-value 0.0005 is one. This means this p-value is safe to assume as a threshold for significance among these differentially expressing genes.

qlf_top_hits <- edgeR::topTags(qlf_test.GLI2vsEV,sort.by = "PValue", n = nrow(filtered_GLI2_matrix))

head(qlf_top_hits)

## Coefficient:  grouped_treatments_normalized$cell_typeYRG 
##            logFC   logCPM         F       PValue         FDR
## ADAM15 -14.66671 5.427443 1252636.1 8.490905e-20 3.69538e-16
## LAMB1  -14.63332 5.416059 1201380.1 9.840550e-20 3.69538e-16
## RRAGA  -14.43536 5.426032 1033729.1 1.672979e-19 3.69538e-16
## SMAP2  -14.84240 5.427397  999721.4 1.882720e-19 3.69538e-16
## DDX18  -14.60997 5.420251  920508.0 2.519831e-19 3.69538e-16
## CASC4  -14.51764 5.430442  856813.2 3.245837e-19 3.69538e-16

length(which(qlf_top_hits$table$PValue < 0.0005))

## [1] 2434

length(which(qlf_top_hits$table$FDR < 0.0005))

## [1] 2433

length(which(qlf_top_hits$table$logFC < 0))

## [1] 11527

Part 15: Thresholded Gene List and Final EMT Gene Detection

The threshold was calculated and based its value I assessed the how many genes actually show traits similar to GLI2. I used P value 1 to eliminate significant portion of the differentially expressed genes. I did not use the LogFC to distinguish between EMT GLI2 vs non-EMT GLI2, because all of logFC values are negative. This indicates there is always up regulation after the Dox treatment and GLI2 expression is always higher than the control. Pretty high confidence.

qlf_tophits_withgn <- merge(GLI2_exp[,1:1], qlf_top_hits, by.y=0,by.x=1,all.y=TRUE)

colnames(qlf_tophits_withgn) <- c("Gene_symbol", "logFC", "logCPM","F", "PValue", "FDR")

qlf_tophits_withgn[,"logarithmic"] <- (-log(qlf_tophits_withgn$PValue))
qlf_tophits_withgn <- qlf_tophits_withgn[order(qlf_tophits_withgn$Gene_symbol),]

GLI2_emt_Genes <- qlf_tophits_withgn$Gene_symbol[which(qlf_tophits_withgn$PValue < 0.0005
                & qlf_tophits_withgn$logFC < 0)]
GLI2_non_emtgenes <- qlf_tophits_withgn$Gene_symbol[which(qlf_tophits_withgn$PValue == 1)]

write.table(x=GLI2_emt_Genes, file = file.path(getwd(),"data","GLI2_emt_Genes.txt"),
             sep = "/", row.names = FALSE, col.names = FALSE, quote = FALSE)
write.table(x=GLI2_non_emtgenes, file = file.path(getwd(),"data","GLI2_non_emtgenes.txt"),
                   sep = "/", row.names = FALSE, col.names = FALSE, quote = FALSE)

Part 16: GProfiler for Upregulation and Downregulation pathway analysis

The GProfiler analysis includes BH correction methods (FDR). I sticked using the same method because I used the same type of method on my previous analysis on FDR portion. For both upregualted and the downregulated genes I have used GO:BP (2022-12-04), Reactome, and WikiPathways( for annotation. These annotations allows for better asessment of my Upregualted genes in terms of defining the biologic pathways they are invovled in.

Upregulated_genes <- read.table(file=file.path(getwd(),"data" ,"GLI2_emt_Genes.txt"),header = TRUE, stringsAsFactors = FALSE, check.names = FALSE)
Upregulated_genes <- Upregulated_genes[4:nrow(Upregulated_genes),]
Upregulated_Gprofiler_validated <- gprofiler2::gost(query = Upregulated_genes, 
                                  organism = "hsapiens", 
                                  exclude_iea = TRUE,
                                  sources = c("GO:BP", "REAC", "WP"),
                                  correction_method = "fdr",
                                  ordered_quer = FALSE,
                                  )

Continuing Analysis

Downregulated_genes <- read.table(file=file.path(getwd(),"data" ,"GLI2_non_emtgenes.txt"),header = TRUE, stringsAsFactors = FALSE, check.names = FALSE)
Downregulated_genes <- Downregulated_genes[13:nrow(Downregulated_genes),]
Downregulated_Gprofiler_validated <- gprofiler2::gost(query = Downregulated_genes,
                                  organism = "hsapiens", 
                                  exclude_iea = TRUE,
                                  correction_method = "fdr",
                                  ordered_quer = FALSE,
                                  source = c("GO:BP", "REAC", "WP"))

Part 17: Subsetting the Gprofiler downregulated and upregualted genes

After subsetting I do have 771 genes that are down regulated. Down regualted genes are invovled in common biological pathways that are not involved in cancerous activities.

Downregulated_genes_filtered <- data.frame(
  term_name = Downregulated_Gprofiler_validated$result$term_name[Downregulated_Gprofiler_validated$result$term_size < 200 &                                                                         Downregulated_Gprofiler_validated$result$term_size > 1],
   term_id  = Downregulated_Gprofiler_validated$result$term_id[Downregulated_Gprofiler_validated$result$term_size < 200 & 
              Downregulated_Gprofiler_validated$result$term_size > 1],
  source  = Downregulated_Gprofiler_validated$result$source[Downregulated_Gprofiler_validated$result$term_size < 200 &
              Downregulated_Gprofiler_validated$result$term_size > 1]
)
length(Downregulated_genes_filtered$term_name)

## [1] 771

knitr::kable(head(Downregulated_genes_filtered, 10), format = "html")

term_name	term_id	source
tRNA metabolic process	GO:0006399	GO:BP
cell cycle checkpoint signaling	GO:0000075	GO:BP
DNA-templated transcription elongation	GO:0006354	GO:BP
tRNA processing	GO:0008033	GO:BP
regulation of DNA-templated transcription elongation	GO:0032784	GO:BP
DNA-templated DNA replication	GO:0006261	GO:BP
DNA integrity checkpoint signaling	GO:0031570	GO:BP
tRNA modification	GO:0006400	GO:BP
regulation of transcription elongation by RNA polymerase II	GO:0034243	GO:BP
transcription elongation by RNA polymerase II	GO:0006368	GO:BP

For Upregulation

After subsetting I do have 1128 genes that are down regulated. Up regualted genes are mostly invovled in cancer activity. Most of the pathwyas are quite invovled in cancerous activty. There is a lot apoptosis and programmed cell death activities.

Upregulated_genes_filtered <- data.frame(
  term_name = Upregulated_Gprofiler_validated$result$term_name[Upregulated_Gprofiler_validated$result$term_size < 200 &                                                                         Upregulated_Gprofiler_validated$result$term_size > 1],
   term_id  = Upregulated_Gprofiler_validated$result$term_id[Upregulated_Gprofiler_validated$result$term_size < 200 & 
              Upregulated_Gprofiler_validated$result$term_size > 1],
  source  = Upregulated_Gprofiler_validated$result$source[Upregulated_Gprofiler_validated$result$term_size < 200 &
              Upregulated_Gprofiler_validated$result$term_size > 1]
)

length(Upregulated_genes_filtered$term_name)

## [1] 1128

knitr::kable(head(Upregulated_Gprofiler_validated, 10), format = "html")

query significant p_value term_size query_size intersection_size precision recall term_id source term_name effective_domain_size source_order parents query_1 TRUE 0.0000000 1495 2057 435 0.2114730 0.2909699 GO:1901566 GO:BP organonitrogen compound biosynthetic process 16307 22681 GO:19015…. query_1 TRUE 0.0000000 763 2057 280 0.1361206 0.3669725 GO:0006518 GO:BP peptide metabolic process 16307 2306 GO:00436…. query_1 TRUE 0.0000000 598 2057 240 0.1166748 0.4013378 GO:0006412 GO:BP translation 16307 2234 GO:00104…. query_1 TRUE 0.0000000 620 2057 242 0.1176471 0.3903226 GO:0043043 GO:BP peptide biosynthetic process 16307 11131 GO:00065…. query_1 TRUE 0.0000000 5451 2057 1036 0.5036461 0.1900569 GO:1901564 GO:BP organonitrogen compound metabolic process 16307 22679 GO:00068…. query_1 TRUE 0.0000000 1006 2057 325 0.1579971 0.3230616 GO:0043603 GO:BP amide metabolic process 16307 11451 GO:0006807 query_1 TRUE 0.0000000 738 2057 267 0.1298007 0.3617886 GO:0043604 GO:BP amide biosynthetic process 16307 11452 GO:00436…. query_1 TRUE 0.0000000 156 2057 108 0.0525036 0.6923077 GO:0002181 GO:BP cytoplasmic translation 16307 753 GO:0006412 query_1 TRUE 0.0000000 2734 2057 618 0.3004375 0.2260424 GO:0044260 GO:BP cellular macromolecule metabolic process 16307 11650 GO:00431…. query_1 TRUE 0.0000000 999 2057 301 0.1463296 0.3013013 GO:0034645 GO:BP cellular macromolecule biosynthetic process 16307 9214 GO:00090…. query_1 TRUE 0.0000000 4506 2057 850 0.4132231 0.1886374 GO:0019538 GO:BP protein metabolic process 16307 6224 GO:00431…. query_1 TRUE 0.0000000 10003 2057 1517 0.7374818 0.1516545 GO:0008152 GO:BP metabolic process 16307 3213 GO:0008150 query_1 TRUE 0.0000000 8618 2057 1350 0.6562956 0.1566489 GO:0044237 GO:BP cellular metabolic process 16307 11638 GO:00081…. query_1 TRUE 0.0000000 88 2057 60 0.0291687 0.6818182 GO:0042773 GO:BP ATP synthesis coupled electron transport 16307 10990 GO:00061…. query_1 TRUE 0.0000000 88 2057 60 0.0291687 0.6818182 GO:0042775 GO:BP mitochondrial ATP synthesis coupled electron transport 16307 10992 GO:0042773 query_1 TRUE 0.0000000 8581 2057 1329 0.6460865 0.1548771 GO:0006807 GO:BP nitrogen compound metabolic process 16307 2557 GO:0008152 query_1 TRUE 0.0000000 99 2057 62 0.0301410 0.6262626 GO:0022904 GO:BP respiratory electron transport chain 16307 7028 GO:00229…. query_1 TRUE 0.0000000 162 2057 81 0.0393777 0.5000000 GO:0009060 GO:BP aerobic respiration 16307 3328 GO:0045333 query_1 TRUE 0.0000000 2062 2057 434 0.2109869 0.2104753 GO:0051246 GO:BP regulation of protein metabolic process 16307 14445 GO:00195…. query_1 TRUE 0.0000000 2153 2057 448 0.2177929 0.2080817 GO:0009056 GO:BP catabolic process 16307 3324 GO:0008152 query_1 TRUE 0.0000000 107 2057 64 0.0311133 0.5981308 GO:0022900 GO:BP electron transport chain 16307 7027 GO:0006091 query_1 TRUE 0.0000000 82 2057 55 0.0267380 0.6707317 GO:0019646 GO:BP aerobic electron transport chain 16307 6321 GO:00061…. query_1 TRUE 0.0000000 191 2057 88 0.0427807 0.4607330 GO:0045333 GO:BP cellular respiration 16307 12133 GO:0015980 query_1 TRUE 0.0000000 129 2057 70 0.0340301 0.5426357 GO:0006119 GO:BP oxidative phosphorylation 16307 2029 GO:0009060 query_1 TRUE 0.0000000 9567 2057 1439 0.6995625 0.1504129 GO:0071704 GO:BP organic substance metabolic process 16307 17953 GO:0008152 query_1 TRUE 0.0000000 9002 2057 1371 0.6665046 0.1522995 GO:0044238 GO:BP primary metabolic process 16307 11639 GO:0008152 query_1 TRUE 0.0000000 1175 2057 283 0.1375790 0.2408511 GO:0009057 GO:BP macromolecule catabolic process 16307 3325 GO:00431…. query_1 TRUE 0.0000000 1874 2057 398 0.1934857 0.2123799 GO:0008104 GO:BP protein localization 16307 3211 GO:0070727 query_1 TRUE 0.0000000 1880 2057 399 0.1939718 0.2122340 GO:0070727 GO:BP cellular macromolecule localization 16307 17331 GO:00330…. query_1 TRUE 0.0000000 2246 2057 453 0.2202236 0.2016919 GO:0033036 GO:BP macromolecule localization 16307 8466 GO:0051179 query_1 TRUE 0.0000000 1752 2057 373 0.1813320 0.2128995 GO:1901575 GO:BP organic substance catabolic process 16307 22686 GO:00090…. query_1 TRUE 0.0000000 856 2057 221 0.1074380 0.2581776 GO:0030163 GO:BP protein catabolic process 16307 7090 GO:00090…. query_1 TRUE 0.0000000 1125 2057 267 0.1298007 0.2373333 GO:0045184 GO:BP establishment of protein localization 16307 12077 GO:00081…. query_1 TRUE 0.0000000 1818 2057 380 0.1847351 0.2090209 GO:0044248 GO:BP cellular catabolic process 16307 11644 GO:00090…. query_1 TRUE 0.0000000 1397 2057 311 0.1511911 0.2226199 GO:0012501 GO:BP programmed cell death 16307 4716 GO:0008219 query_1 TRUE 0.0000000 1538 2057 334 0.1623724 0.2171651 GO:0008219 GO:BP cell death 16307 3234 GO:0009987 query_1 TRUE 0.0000000 392 2057 127 0.0617404 0.3239796 GO:0022613 GO:BP ribonucleoprotein complex biogenesis 16307 7017 GO:0044085 query_1 TRUE 0.0000000 2733 2057 515 0.2503646 0.1884376 GO:0051641 GO:BP cellular localization 16307 14725 GO:00099…. query_1 TRUE 0.0000000 1149 2057 266 0.1293145 0.2315057 GO:1901565 GO:BP organonitrogen compound catabolic process 16307 22680 GO:19015…. query_1 TRUE 0.0000000 1342 2057 297 0.1443850 0.2213115 GO:0006915 GO:BP apoptotic process 16307 2636 GO:0012501 query_1 TRUE 0.0000000 1527 2057 327 0.1589694 0.2141454 GO:0043933 GO:BP protein-containing complex organization 16307 11528 GO:0016043 query_1 TRUE 0.0000000 1356 2057 298 0.1448712 0.2197640 GO:0065003 GO:BP protein-containing complex assembly 16307 16924 GO:00226…. query_1 TRUE 0.0000000 1382 2057 302 0.1468158 0.2185239 GO:0046907 GO:BP intracellular transport 16307 13236 GO:00068…. query_1 TRUE 0.0000000 1082 2057 250 0.1215362 0.2310536 GO:0043067 GO:BP regulation of programmed cell death 16307 11152 GO:00109…. query_1 TRUE 0.0000000 381 2057 121 0.0588235 0.3175853 GO:0006091 GO:BP generation of precursor metabolites and energy 16307 2006 GO:0044237 query_1 TRUE 0.0000000 254 2057 93 0.0452115 0.3661417 GO:0015980 GO:BP energy derivation by oxidation of organic compounds 16307 5216 GO:0006091 query_1 TRUE 0.0000000 1028 2057 240 0.1166748 0.2334630 GO:0015031 GO:BP protein transport 16307 4945 GO:00451…. query_1 TRUE 0.0000000 2770 2057 512 0.2489062 0.1848375 GO:0044085 GO:BP cellular component biogenesis 16307 11606 GO:0071840 query_1 TRUE 0.0000000 201 2057 80 0.0388916 0.3980100 GO:0046390 GO:BP ribose phosphate biosynthetic process 16307 12900 GO:00196…. query_1 TRUE 0.0000000 1208 2057 269 0.1307730 0.2226821 GO:0010941 GO:BP regulation of cell death 16307 4663 GO:00082…. query_1 TRUE 0.0000000 202 2057 80 0.0388916 0.3960396 GO:0071826 GO:BP ribonucleoprotein complex subunit organization 16307 18015 GO:0043933 query_1 TRUE 0.0000000 194 2057 78 0.0379193 0.4020619 GO:0009260 GO:BP ribonucleotide biosynthetic process 16307 3517 GO:00091…. query_1 TRUE 0.0000000 5580 2057 901 0.4380165 0.1614695 GO:0071840 GO:BP cellular component organization or biogenesis 16307 18026 GO:0009987 query_1 TRUE 0.0000000 1716 2057 350 0.1701507 0.2039627 GO:0051649 GO:BP establishment of localization in cell 16307 14733 GO:00512…. query_1 TRUE 0.0000000 704 2057 181 0.0879922 0.2571023 GO:0006886 GO:BP intracellular protein transport 16307 2614 GO:00081…. query_1 TRUE 0.0000000 767 2057 192 0.0933398 0.2503259 GO:0033365 GO:BP protein localization to organelle 16307 8652 GO:0008104 query_1 TRUE 0.0000000 248 2057 90 0.0437530 0.3629032 GO:0009165 GO:BP nucleotide biosynthetic process 16307 3423 GO:00091…. query_1 TRUE 0.0000000 469 2057 136 0.0661157 0.2899787 GO:0007005 GO:BP mitochondrion organization 16307 2692 GO:0006996 query_1 TRUE 0.0000000 185 2057 75 0.0364609 0.4054054 GO:0009152 GO:BP purine ribonucleotide biosynthetic process 16307 3411 GO:00061…. query_1 TRUE 0.0000000 255 2057 91 0.0442392 0.3568627 GO:1901293 GO:BP nucleoside phosphate biosynthetic process 16307 22439 GO:00067…. query_1 TRUE 0.0000000 628 2057 165 0.0802139 0.2627389 GO:0043069 GO:BP negative regulation of programmed cell death 16307 11154 GO:00125…. query_1 TRUE 0.0000000 1057 2057 240 0.1166748 0.2270577 GO:0042981 GO:BP regulation of apoptotic process 16307 11103 GO:00069…. query_1 TRUE 0.0000000 703 2057 178 0.0865338 0.2532006 GO:0060548 GO:BP negative regulation of cell death 16307 15674 GO:00082…. query_1 TRUE 0.0000000 194 2057 76 0.0369470 0.3917526 GO:0022618 GO:BP ribonucleoprotein complex assembly 16307 7022 GO:00226…. query_1 TRUE 0.0000000 1413 2057 296 0.1438989 0.2094834 GO:0071705 GO:BP nitrogen compound transport 16307 17954 GO:0006810 query_1 TRUE 0.0000000 99 2057 50 0.0243072 0.5050505 GO:0009201 GO:BP ribonucleoside triphosphate biosynthetic process 16307 3459 GO:00091…. query_1 TRUE 0.0000000 568 2057 150 0.0729217 0.2640845 GO:0055086 GO:BP nucleobase-containing small molecule metabolic process 16307 15162 GO:00061…. query_1 TRUE 0.0000000 225 2057 81 0.0393777 0.3600000 GO:0006164 GO:BP purine nucleotide biosynthetic process 16307 2051 GO:00061…. query_1 TRUE 0.0000000 108 2057 52 0.0252795 0.4814815 GO:0009142 GO:BP nucleoside triphosphate biosynthetic process 16307 3401 GO:00091…. query_1 TRUE 0.0000000 94 2057 48 0.0233350 0.5106383 GO:0009145 GO:BP purine nucleoside triphosphate biosynthetic process 16307 3404 GO:00091…. query_1 TRUE 0.0000000 94 2057 48 0.0233350 0.5106383 GO:0009206 GO:BP purine ribonucleoside triphosphate biosynthetic process 16307 3464 GO:00091…. query_1 TRUE 0.0000000 614 2057 158 0.0768109 0.2573290 GO:0043066 GO:BP negative regulation of apoptotic process 16307 11151 GO:00069…. query_1 TRUE 0.0000000 343 2057 106 0.0515314 0.3090379 GO:0016032 GO:BP viral process 16307 5227 GO:0008150 query_1 TRUE 0.0000000 496 2057 136 0.0661157 0.2741935 GO:0009117 GO:BP nucleotide metabolic process 16307 3378 GO:0006753 query_1 TRUE 0.0000000 231 2057 82 0.0398639 0.3549784 GO:0072522 GO:BP purine-containing compound biosynthetic process 16307 18529 GO:00181…. query_1 TRUE 0.0000000 506 2057 137 0.0666018 0.2707510 GO:0006753 GO:BP nucleoside phosphate metabolic process 16307 2518 GO:00067…. query_1 TRUE 0.0000000 882 2057 204 0.0991736 0.2312925 GO:0044265 GO:BP cellular macromolecule catabolic process 16307 11653 GO:00090…. query_1 TRUE 0.0000000 3183 2057 555 0.2698104 0.1743638 GO:0006996 GO:BP organelle organization 16307 2686 GO:0016043 query_1 TRUE 0.0000000 690 2057 170 0.0826446 0.2463768 GO:0051603 GO:BP proteolysis involved in protein catabolic process 16307 14691 GO:00065…. query_1 TRUE 0.0000000 67 2057 39 0.0189596 0.5820896 GO:0042776 GO:BP proton motive force-driven mitochondrial ATP synthesis 16307 10993 GO:00061…. query_1 TRUE 0.0000000 74 2057 41 0.0199319 0.5540541 GO:0015986 GO:BP proton motive force-driven ATP synthesis 16307 5218 GO:0006754 query_1 TRUE 0.0000000 5407 2057 859 0.4175984 0.1588681 GO:0016043 GO:BP cellular component organization 16307 5233 GO:0071840 query_1 TRUE 0.0000000 2558 2057 463 0.2250851 0.1810008 GO:0022607 GO:BP cellular component assembly 16307 7012 GO:00160…. query_1 TRUE 0.0000000 92 2057 46 0.0223627 0.5000000 GO:0006754 GO:BP ATP biosynthetic process 16307 2519 GO:00091…. query_1 TRUE 0.0000000 843 2057 195 0.0947982 0.2313167 GO:0009894 GO:BP regulation of catabolic process 16307 3848 GO:00090…. query_1 TRUE 0.0000000 386 2057 112 0.0544482 0.2901554 GO:0019693 GO:BP ribose phosphate metabolic process 16307 6365 GO:00067…. query_1 TRUE 0.0000000 130 2057 56 0.0272241 0.4307692 GO:0032543 GO:BP mitochondrial translation 16307 8100 GO:00064…. query_1 TRUE 0.0000000 1434 2057 291 0.1414682 0.2029289 GO:0006508 GO:BP proteolysis 16307 2299 GO:0019538 query_1 TRUE 0.0000000 794 2057 186 0.0904229 0.2342569 GO:0051248 GO:BP negative regulation of protein metabolic process 16307 14447 GO:00106…. query_1 TRUE 0.0000000 378 2057 110 0.0534759 0.2910053 GO:0009259 GO:BP ribonucleotide metabolic process 16307 3516 GO:00091…. query_1 TRUE 0.0000000 5147 2057 821 0.3991249 0.1595104 GO:1901576 GO:BP organic substance biosynthetic process 16307 22687 GO:00090…. query_1 TRUE 0.0000000 46 2057 31 0.0150705 0.6739130 GO:0006120 GO:BP mitochondrial electron transport, NADH to ubiquinone 16307 2030 GO:00196…. query_1 TRUE 0.0000000 390 2057 112 0.0544482 0.2871795 GO:0008380 GO:BP RNA splicing 16307 3277 GO:0006396 query_1 TRUE 0.0000000 933 2057 209 0.1016043 0.2240086 GO:1901135 GO:BP carbohydrate derivative metabolic process 16307 22307 GO:0071704 query_1 TRUE 0.0000000 5587 2057 878 0.4268352 0.1571505 GO:0034641 GO:BP cellular nitrogen compound metabolic process 16307 9210 GO:00068…. query_1 TRUE 0.0000000 367 2057 107 0.0520175 0.2915531 GO:0009150 GO:BP purine ribonucleotide metabolic process 16307 3409 GO:00061…. query_1 TRUE 0.0000000 5207 2057 827 0.4020418 0.1588247 GO:0009058 GO:BP biosynthetic process 16307 3326 GO:0008152 query_1 TRUE 0.0000000 289 2057 91 0.0442392 0.3148789 GO:0000375 GO:BP RNA splicing, via transesterification reactions 16307 115 GO:0008380 query_1 TRUE 0.0000000 452 2057 123 0.0597958 0.2721239 GO:0006163 GO:BP purine nucleotide metabolic process 16307 2050 GO:00091…. query_1 TRUE 0.0000000 285 2057 90 0.0437530 0.3157895 GO:0000398 GO:BP mRNA splicing, via spliceosome 16307 129 GO:00003…. query_1 TRUE 0.0000000 285 2057 90 0.0437530 0.3157895 GO:0000377 GO:BP RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 16307 117 GO:0000375 query_1 TRUE 0.0000000 14876 2057 1969 0.9572193 0.1323608 GO:0009987 GO:BP cellular process 16307 3905 GO:0008150 query_1 TRUE 0.0000000 477 2057 127 0.0617404 0.2662474 GO:0072521 GO:BP purine-containing compound metabolic process 16307 18528 GO:00067…. query_1 TRUE 0.0000000 112 2057 50 0.0243072 0.4464286 GO:0006413 GO:BP translational initiation 16307 2235 GO:00064…. query_1 TRUE 0.0000000 8109 2057 1199 0.5828877 0.1478604 GO:0043170 GO:BP macromolecule metabolic process 16307 11211 GO:0071704 query_1 TRUE 0.0000000 571 2057 144 0.0700049 0.2521891 GO:1901137 GO:BP carbohydrate derivative biosynthetic process 16307 22309 GO:19011…. query_1 TRUE 0.0000000 219 2057 75 0.0364609 0.3424658 GO:0009141 GO:BP nucleoside triphosphate metabolic process 16307 3400 GO:0006753 query_1 TRUE 0.0000000 5086 2057 807 0.3923189 0.1586709 GO:0044249 GO:BP cellular biosynthetic process 16307 11645 GO:00090…. query_1 TRUE 0.0000000 131 2057 54 0.0262518 0.4122137 GO:2001242 GO:BP regulation of intrinsic apoptotic signaling pathway 16307 27889 GO:00971…. query_1 TRUE 0.0000000 204 2057 71 0.0345163 0.3480392 GO:0009199 GO:BP ribonucleoside triphosphate metabolic process 16307 3457 GO:0009141 query_1 TRUE 0.0000000 671 2057 160 0.0777832 0.2384501 GO:0032880 GO:BP regulation of protein localization 16307 8345 GO:00081…. query_1 TRUE 0.0000000 456 2057 121 0.0588235 0.2653509 GO:0097190 GO:BP apoptotic signaling pathway 16307 19703 GO:00069…. query_1 TRUE 0.0000000 184 2057 66 0.0320856 0.3586957 GO:0046034 GO:BP ATP metabolic process 16307 12587 GO:00091…. query_1 TRUE 0.0000000 158 2057 60 0.0291687 0.3797468 GO:0140053 GO:BP mitochondrial gene expression 16307 20877 GO:0010467 query_1 TRUE 0.0000000 431 2057 116 0.0563928 0.2691415 GO:0010608 GO:BP post-transcriptional regulation of gene expression 16307 4373 GO:0010468 query_1 TRUE 0.0000000 389 2057 108 0.0525036 0.2776350 GO:0034248 GO:BP regulation of amide metabolic process 16307 9016 GO:00436…. query_1 TRUE 0.0000000 551 2057 138 0.0670880 0.2504537 GO:0030162 GO:BP regulation of proteolysis 16307 7089 GO:00065…. query_1 TRUE 0.0000000 198 2057 69 0.0335440 0.3484848 GO:0009205 GO:BP purine ribonucleoside triphosphate metabolic process 16307 3463 GO:00091…. query_1 TRUE 0.0000000 235 2057 77 0.0374332 0.3276596 GO:0097193 GO:BP intrinsic apoptotic signaling pathway 16307 19706 GO:00355…. query_1 TRUE 0.0000000 592 2057 145 0.0704910 0.2449324 GO:0019941 GO:BP modification-dependent protein catabolic process 16307 6456 GO:00436…. query_1 TRUE 0.0000000 765 2057 175 0.0850754 0.2287582 GO:0060341 GO:BP regulation of cellular localization 16307 15480 GO:00328…. query_1 TRUE 0.0000000 1758 2057 333 0.1618862 0.1894198 GO:0071702 GO:BP organic substance transport 16307 17951 GO:0006810 query_1 TRUE 0.0000000 367 2057 103 0.0500729 0.2806540 GO:0072594 GO:BP establishment of protein localization to organelle 16307 18564 GO:00333…. query_1 TRUE 0.0000000 201 2057 69 0.0335440 0.3432836 GO:0009144 GO:BP purine nucleoside triphosphate metabolic process 16307 3403 GO:0009141 query_1 TRUE 0.0000000 492 2057 126 0.0612543 0.2560976 GO:0010498 GO:BP proteasomal protein catabolic process 16307 4287 GO:00301…. query_1 TRUE 0.0000000 59 2057 33 0.0160428 0.5593220 GO:0010257 GO:BP NADH dehydrogenase complex assembly 16307 4132 GO:0065003 query_1 TRUE 0.0000000 59 2057 33 0.0160428 0.5593220 GO:0032981 GO:BP mitochondrial respiratory chain complex I assembly 16307 8432 GO:00102…. query_1 TRUE 0.0000000 377 2057 104 0.0505591 0.2758621 GO:0006397 GO:BP mRNA processing 16307 2221 GO:00063…. query_1 TRUE 0.0000000 1637 2057 312 0.1516772 0.1905925 GO:0033554 GO:BP cellular response to stress 16307 8768 GO:00069…. query_1 TRUE 0.0000000 604 2057 145 0.0704910 0.2400662 GO:0043632 GO:BP modification-dependent macromolecule catabolic process 16307 11474 GO:0044265 query_1 TRUE 0.0000000 610 2057 146 0.0709772 0.2393443 GO:0016071 GO:BP mRNA metabolic process 16307 5255 GO:0016070 query_1 TRUE 0.0000000 183 2057 64 0.0311133 0.3497268 GO:0006457 GO:BP protein folding 16307 2267 GO:0009987 query_1 TRUE 0.0000000 4274 2057 687 0.3339815 0.1607394 GO:0044271 GO:BP cellular nitrogen compound biosynthetic process 16307 11656 GO:00346…. query_1 TRUE 0.0000000 584 2057 140 0.0680603 0.2397260 GO:0006511 GO:BP ubiquitin-dependent protein catabolic process 16307 2301 GO:0019941 query_1 TRUE 0.0000000 1534 2057 293 0.1424404 0.1910039 GO:0044281 GO:BP small molecule metabolic process 16307 11662 GO:0008152 query_1 TRUE 0.0000000 264 2057 80 0.0388916 0.3030303 GO:2001233 GO:BP regulation of apoptotic signaling pathway 16307 27880 GO:00099…. query_1 TRUE 0.0000000 336 2057 94 0.0456976 0.2797619 GO:0006417 GO:BP regulation of translation 16307 2238 GO:00064…. query_1 TRUE 0.0000000 1021 2057 211 0.1025766 0.2066601 GO:0033043 GO:BP regulation of organelle organization 16307 8468 GO:00069…. query_1 TRUE 0.0000000 300 2057 86 0.0418085 0.2866667 GO:0042176 GO:BP regulation of protein catabolic process 16307 10631 GO:00098…. query_1 TRUE 0.0000000 367 2057 98 0.0476422 0.2670300 GO:1903829 GO:BP positive regulation of protein localization 16307 24571 GO:00081…. query_1 TRUE 0.0000000 858 2057 183 0.0889645 0.2132867 GO:0006396 GO:BP RNA processing 16307 2220 GO:00104…. query_1 TRUE 0.0000000 1249 2057 245 0.1191055 0.1961569 GO:0051247 GO:BP positive regulation of protein metabolic process 16307 14446 GO:00106…. query_1 TRUE 0.0000000 423 2057 107 0.0520175 0.2529551 GO:0043161 GO:BP proteasome-mediated ubiquitin-dependent protein catabolic process 16307 11206 GO:00065…. query_1 TRUE 0.0000000 231 2057 70 0.0340301 0.3030303 GO:0034976 GO:BP response to endoplasmic reticulum stress 16307 9268 GO:0033554 query_1 TRUE 0.0000000 694 2057 153 0.0743802 0.2204611 GO:0031329 GO:BP regulation of cellular catabolic process 16307 7555 GO:00098…. query_1 TRUE 0.0000000 295 2057 82 0.0398639 0.2779661 GO:0031647 GO:BP regulation of protein stability 16307 7700 GO:0065008 query_1 TRUE 0.0000000 94 2057 39 0.0189596 0.4148936 GO:0033108 GO:BP mitochondrial respiratory chain complex assembly 16307 8512 GO:00070…. query_1 TRUE 0.0000000 241 2057 71 0.0345163 0.2946058 GO:0019058 GO:BP viral life cycle 16307 5883 GO:0016032 query_1 TRUE 0.0000000 401 2057 101 0.0491006 0.2518703 GO:0070201 GO:BP regulation of establishment of protein localization 16307 17025 GO:00328…. query_1 TRUE 0.0000000 492 2057 117 0.0568789 0.2378049 GO:0072657 GO:BP protein localization to membrane 16307 18584 GO:00081…. query_1 TRUE 0.0000000 517 2057 121 0.0588235 0.2340426 GO:0090407 GO:BP organophosphate biosynthetic process 16307 19433 GO:00196…. query_1 TRUE 0.0000000 4385 2057 684 0.3325231 0.1559863 GO:0051179 GO:BP localization 16307 14406 GO:0008150 query_1 TRUE 0.0000000 410 2057 102 0.0495868 0.2487805 GO:2000112 GO:BP regulation of cellular macromolecule biosynthetic process 16307 26871 GO:00105…. query_1 TRUE 0.0000000 316 2057 84 0.0408362 0.2658228 GO:0045862 GO:BP positive regulation of proteolysis 16307 12450 GO:00065…. query_1 TRUE 0.0000000 582 2057 131 0.0636850 0.2250859 GO:0051668 GO:BP localization within membrane 16307 14751 GO:0051641 query_1 TRUE 0.0000000 301 2057 81 0.0393777 0.2691030 GO:0052547 GO:BP regulation of peptidase activity 16307 15045 GO:00301…. query_1 TRUE 0.0000000 280 2057 77 0.0374332 0.2750000 GO:0006605 GO:BP protein targeting 16307 2389 GO:0006886 query_1 TRUE 0.0000000 209 2057 63 0.0306271 0.3014354 GO:1903320 GO:BP regulation of protein modification by small protein conjugation or removal 16307 24123 GO:00313…. query_1 TRUE 0.0000000 245 2057 70 0.0340301 0.2857143 GO:1904951 GO:BP positive regulation of establishment of protein localization 16307 25552 GO:00451…. query_1 TRUE 0.0000000 247 2057 70 0.0340301 0.2834008 GO:0042254 GO:BP ribosome biogenesis 16307 10687 GO:0022613 query_1 TRUE 0.0000000 1514 2057 276 0.1341760 0.1822985 GO:0050790 GO:BP regulation of catalytic activity 16307 14088 GO:0065009 query_1 TRUE 0.0000000 77 2057 33 0.0160428 0.4285714 GO:0006446 GO:BP regulation of translational initiation 16307 2260 GO:00064…. query_1 TRUE 0.0000000 146 2057 49 0.0238211 0.3356164 GO:0006403 GO:BP RNA localization 16307 2227 GO:0033036 query_1 TRUE 0.0000000 66 2057 30 0.0145843 0.4545455 GO:1900182 GO:BP positive regulation of protein localization to nucleus 16307 21490 GO:00345…. query_1 TRUE 0.0000000 39 2057 22 0.0106952 0.5641026 GO:0002183 GO:BP cytoplasmic translational initiation 16307 755 GO:00021…. query_1 TRUE 0.0000000 1932 2057 335 0.1628585 0.1733954 GO:0051128 GO:BP regulation of cellular component organization 16307 14357 GO:00160…. query_1 TRUE 0.0000000 1618 2057 289 0.1404959 0.1786156 GO:0032879 GO:BP regulation of localization 16307 8344 GO:00507…. query_1 TRUE 0.0000000 233 2057 66 0.0320856 0.2832618 GO:0090150 GO:BP establishment of protein localization to membrane 16307 19203 GO:00451…. query_1 TRUE 0.0000000 885 2057 177 0.0860476 0.2000000 GO:0019637 GO:BP organophosphate metabolic process 16307 6315 GO:00067…. query_1 TRUE 0.0000000 3176 2057 510 0.2479339 0.1605793 GO:0009893 GO:BP positive regulation of metabolic process 16307 3847 GO:00081…. query_1 TRUE 0.0000000 277 2057 74 0.0359747 0.2671480 GO:0032386 GO:BP regulation of intracellular transport 16307 8001 GO:00469…. query_1 TRUE 0.0000000 170 2057 53 0.0257657 0.3117647 GO:2001234 GO:BP negative regulation of apoptotic signaling pathway 16307 27881 GO:00099…. query_1 TRUE 0.0000000 15 2057 13 0.0063199 0.8666667 GO:1904874 GO:BP positive regulation of telomerase RNA localization to Cajal body 16307 25485 GO:00485…. query_1 TRUE 0.0000000 15 2057 13 0.0063199 0.8666667 GO:0001732 GO:BP formation of cytoplasmic translation initiation complex 16307 432 GO:00021…. query_1 TRUE 0.0000000 3797 2057 594 0.2887701 0.1564393 GO:0051234 GO:BP establishment of localization 16307 14436 GO:0051179 query_1 TRUE 0.0000000 135 2057 45 0.0218765 0.3333333 GO:0010821 GO:BP regulation of mitochondrion organization 16307 4565 GO:00070…. query_1 TRUE 0.0000000 79 2057 32 0.0155566 0.4050633 GO:2001243 GO:BP negative regulation of intrinsic apoptotic signaling pathway 16307 27890 GO:00971…. query_1 TRUE 0.0000000 278 2057 73 0.0354886 0.2625899 GO:0052548 GO:BP regulation of endopeptidase activity 16307 15046 GO:0052547 query_1 TRUE 0.0000000 170 2057 52 0.0252795 0.3058824 GO:0043484 GO:BP regulation of RNA splicing 16307 11381 GO:00083…. query_1 TRUE 0.0000000 5255 2057 786 0.3821099 0.1495718 GO:0010467 GO:BP gene expression 16307 4270 GO:0043170 query_1 TRUE 0.0000000 379 2057 91 0.0442392 0.2401055 GO:0051223 GO:BP regulation of protein transport 16307 14428 GO:00150…. query_1 TRUE 0.0000000 4394 2057 671 0.3262032 0.1527082 GO:0048519 GO:BP negative regulation of biological process 16307 13623 GO:00081…. query_1 TRUE 0.0000000 919 2057 179 0.0870199 0.1947769 GO:0010628 GO:BP positive regulation of gene expression 16307 4392 GO:00104…. query_1 TRUE 0.0000000 183 2057 54 0.0262518 0.2950820 GO:0033157 GO:BP regulation of intracellular protein transport 16307 8537 GO:00068…. query_1 TRUE 0.0000001 278 2057 72 0.0350024 0.2589928 GO:1903311 GO:BP regulation of mRNA metabolic process 16307 24114 GO:00160…. query_1 TRUE 0.0000001 179 2057 53 0.0257657 0.2960894 GO:0034249 GO:BP negative regulation of amide metabolic process 16307 9017 GO:00342…. query_1 TRUE 0.0000001 811 2057 161 0.0782693 0.1985203 GO:0010629 GO:BP negative regulation of gene expression 16307 4393 GO:00104…. query_1 TRUE 0.0000001 820 2057 162 0.0787555 0.1975610 GO:0000278 GO:BP mitotic cell cycle 16307 80 GO:0007049 query_1 TRUE 0.0000001 96 2057 35 0.0170151 0.3645833 GO:1900180 GO:BP regulation of protein localization to nucleus 16307 21488 GO:00328…. query_1 TRUE 0.0000001 2141 2057 357 0.1735537 0.1667445 GO:0065009 GO:BP regulation of molecular function 16307 16929 GO:0065007 query_1 TRUE 0.0000001 478 2057 106 0.0515314 0.2217573 GO:0006914 GO:BP autophagy 16307 2635 GO:00442…. query_1 TRUE 0.0000001 478 2057 106 0.0515314 0.2217573 GO:0061919 GO:BP process utilizing autophagic mechanism 16307 16756 GO:0009987 query_1 TRUE 0.0000001 1437 2057 255 0.1239669 0.1774530 GO:1902531 GO:BP regulation of intracellular signal transduction 16307 23502 GO:00099…. query_1 TRUE 0.0000002 2886 2057 460 0.2236266 0.1593902 GO:0010604 GO:BP positive regulation of macromolecule metabolic process 16307 4369 GO:00098…. query_1 TRUE 0.0000002 53 2057 24 0.0116675 0.4528302 GO:0042255 GO:BP ribosome assembly 16307 10688 GO:00422…. query_1 TRUE 0.0000002 2257 2057 372 0.1808459 0.1648206 GO:0010605 GO:BP negative regulation of macromolecule metabolic process 16307 4370 GO:00098…. query_1 TRUE 0.0000002 117 2057 39 0.0189596 0.3333333 GO:0070585 GO:BP protein localization to mitochondrion 16307 17244 GO:0033365 query_1 TRUE 0.0000002 2559 2057 414 0.2012640 0.1617819 GO:0051173 GO:BP positive regulation of nitrogen compound metabolic process 16307 14401 GO:00068…. query_1 TRUE 0.0000002 171 2057 50 0.0243072 0.2923977 GO:0032388 GO:BP positive regulation of intracellular transport 16307 8003 GO:00323…. query_1 TRUE 0.0000002 1736 2057 297 0.1443850 0.1710829 GO:0010033 GO:BP response to organic substance 16307 3939 GO:0042221 query_1 TRUE 0.0000003 2361 2057 386 0.1876519 0.1634900 GO:0006793 GO:BP phosphorus metabolic process 16307 2548 GO:0044237 query_1 TRUE 0.0000003 725 2057 145 0.0704910 0.2000000 GO:0051338 GO:BP regulation of transferase activity 16307 14517 GO:0050790 query_1 TRUE 0.0000003 5329 2057 787 0.3825960 0.1476825 GO:0048518 GO:BP positive regulation of biological process 16307 13622 GO:00081…. query_1 TRUE 0.0000003 229 2057 61 0.0296548 0.2663755 GO:0051222 GO:BP positive regulation of protein transport 16307 14427 GO:00150…. query_1 TRUE 0.0000003 157 2057 47 0.0228488 0.2993631 GO:0006839 GO:BP mitochondrial transport 16307 2578 GO:0046907 query_1 TRUE 0.0000003 2430 2057 395 0.1920272 0.1625514 GO:0009892 GO:BP negative regulation of metabolic process 16307 3846 GO:00081…. query_1 TRUE 0.0000003 609 2057 126 0.0612543 0.2068966 GO:0080135 GO:BP regulation of cellular response to stress 16307 18943 GO:00335…. query_1 TRUE 0.0000003 4712 2057 705 0.3427321 0.1496180 GO:0048522 GO:BP positive regulation of cellular process 16307 13626 GO:00099…. query_1 TRUE 0.0000004 3898 2057 596 0.2897423 0.1528989 GO:0048523 GO:BP negative regulation of cellular process 16307 13627 GO:00099…. query_1 TRUE 0.0000004 18 2057 13 0.0063199 0.7222222 GO:1904872 GO:BP regulation of telomerase RNA localization to Cajal body 16307 25483 GO:00328…. query_1 TRUE 0.0000004 231 2057 61 0.0296548 0.2640693 GO:0034504 GO:BP protein localization to nucleus 16307 9175 GO:0033365 query_1 TRUE 0.0000004 51 2057 23 0.0111813 0.4509804 GO:0001836 GO:BP release of cytochrome c from mitochondria 16307 514 GO:00086…. query_1 TRUE 0.0000005 63 2057 26 0.0126398 0.4126984 GO:0061077 GO:BP chaperone-mediated protein folding 16307 16160 GO:0006457 query_1 TRUE 0.0000006 2638 2057 422 0.2051531 0.1599697 GO:0042221 GO:BP response to chemical 16307 10676 GO:0050896 query_1 TRUE 0.0000008 821 2057 158 0.0768109 0.1924482 GO:1902533 GO:BP positive regulation of intracellular signal transduction 16307 23504 GO:00099…. query_1 TRUE 0.0000008 172 2057 49 0.0238211 0.2848837 GO:0031396 GO:BP regulation of protein ubiquitination 16307 7588 GO:00165…. query_1 TRUE 0.0000008 2342 2057 380 0.1847351 0.1622545 GO:0006796 GO:BP phosphate-containing compound metabolic process 16307 2551 GO:0006793 query_1 TRUE 0.0000009 128 2057 40 0.0194458 0.3125000 GO:0006888 GO:BP endoplasmic reticulum to Golgi vesicle-mediated transport 16307 2616 GO:00469…. query_1 TRUE 0.0000010 19 2057 13 0.0063199 0.6842105 GO:0090671 GO:BP telomerase RNA localization to Cajal body 16307 19567 GO:00906…. query_1 TRUE 0.0000010 19 2057 13 0.0063199 0.6842105 GO:0090672 GO:BP telomerase RNA localization 16307 19568 GO:0006403 query_1 TRUE 0.0000010 158 2057 46 0.0223627 0.2911392 GO:0017148 GO:BP negative regulation of translation 16307 5452 GO:00064…. query_1 TRUE 0.0000010 100 2057 34 0.0165289 0.3400000 GO:0048024 GO:BP regulation of mRNA splicing, via spliceosome 16307 13291 GO:00003…. query_1 TRUE 0.0000010 19 2057 13 0.0063199 0.6842105 GO:0090685 GO:BP RNA localization to nucleus 16307 19577 GO:0006403 query_1 TRUE 0.0000010 19 2057 13 0.0063199 0.6842105 GO:0090670 GO:BP RNA localization to Cajal body 16307 19566 GO:0090685 query_1 TRUE 0.0000011 119 2057 38 0.0184735 0.3193277 GO:0019079 GO:BP viral genome replication 16307 5898 GO:00160…. query_1 TRUE 0.0000011 200 2057 54 0.0262518 0.2700000 GO:0050821 GO:BP protein stabilization 16307 14112 GO:0031647 query_1 TRUE 0.0000011 174 2057 49 0.0238211 0.2816092 GO:2000113 GO:BP negative regulation of cellular macromolecule biosynthetic process 16307 26872 GO:00105…. query_1 TRUE 0.0000012 74 2057 28 0.0136121 0.3783784 GO:0042273 GO:BP ribosomal large subunit biogenesis 16307 10698 GO:00226…. query_1 TRUE 0.0000012 705 2057 139 0.0675741 0.1971631 GO:0051050 GO:BP positive regulation of transport 16307 14303 GO:00068…. query_1 TRUE 0.0000012 35 2057 18 0.0087506 0.5142857 GO:0009123 GO:BP nucleoside monophosphate metabolic process 16307 3382 GO:0006753 query_1 TRUE 0.0000012 680 2057 135 0.0656296 0.1985294 GO:1903047 GO:BP mitotic cell cycle process 16307 23916 GO:00002…. query_1 TRUE 0.0000013 92 2057 32 0.0155566 0.3478261 GO:0008637 GO:BP apoptotic mitochondrial changes 16307 3312 GO:00069…. query_1 TRUE 0.0000014 125 2057 39 0.0189596 0.3120000 GO:0035966 GO:BP response to topologically incorrect protein 16307 9928 GO:00069…. query_1 TRUE 0.0000015 97 2057 33 0.0160428 0.3402062 GO:0006626 GO:BP protein targeting to mitochondrion 16307 2407 GO:00066…. query_1 TRUE 0.0000017 3185 2057 494 0.2401556 0.1551020 GO:0006950 GO:BP response to stress 16307 2656 GO:0050896 query_1 TRUE 0.0000018 131 2057 40 0.0194458 0.3053435 GO:0090316 GO:BP positive regulation of intracellular protein transport 16307 19354 GO:00068…. query_1 TRUE 0.0000018 274 2057 67 0.0325717 0.2445255 GO:0009895 GO:BP negative regulation of catabolic process 16307 3849 GO:00090…. query_1 TRUE 0.0000018 516 2057 108 0.0525036 0.2093023 GO:0010256 GO:BP endomembrane system organization 16307 4131 GO:0016043 query_1 TRUE 0.0000019 112 2057 36 0.0175012 0.3214286 GO:0072655 GO:BP establishment of protein localization to mitochondrion 16307 18582 GO:00705…. query_1 TRUE 0.0000020 554 2057 114 0.0554205 0.2057762 GO:0051276 GO:BP chromosome organization 16307 14465 GO:0006996 query_1 TRUE 0.0000020 332 2057 77 0.0374332 0.2319277 GO:0140694 GO:BP non-membrane-bounded organelle assembly 16307 21093 GO:0070925 query_1 TRUE 0.0000023 108 2057 35 0.0170151 0.3240741 GO:0036503 GO:BP ERAD pathway 16307 10226 GO:00102…. query_1 TRUE 0.0000024 4233 2057 634 0.3082158 0.1497756 GO:0009059 GO:BP macromolecule biosynthetic process 16307 3327 GO:00431…. query_1 TRUE 0.0000025 10 2057 9 0.0043753 0.9000000 GO:1904851 GO:BP positive regulation of establishment of protein localization to telomere 16307 25466 GO:00702…. query_1 TRUE 0.0000027 104 2057 34 0.0165289 0.3269231 GO:0006986 GO:BP response to unfolded protein 16307 2682 GO:0035966 query_1 TRUE 0.0000029 44 2057 20 0.0097229 0.4545455 GO:2001244 GO:BP positive regulation of intrinsic apoptotic signaling pathway 16307 27891 GO:00971…. query_1 TRUE 0.0000030 1931 2057 318 0.1545941 0.1646815 GO:0051172 GO:BP negative regulation of nitrogen compound metabolic process 16307 14400 GO:00068…. query_1 TRUE 0.0000033 149 2057 43 0.0209042 0.2885906 GO:0034250 GO:BP positive regulation of amide metabolic process 16307 9018 GO:00342…. query_1 TRUE 0.0000033 129 2057 39 0.0189596 0.3023256 GO:0050684 GO:BP regulation of mRNA processing 16307 14042 GO:00063…. query_1 TRUE 0.0000036 3640 2057 553 0.2688381 0.1519231 GO:0006810 GO:BP transport 16307 2560 GO:0051234 query_1 TRUE 0.0000040 65 2057 25 0.0121536 0.3846154 GO:0051205 GO:BP protein insertion into membrane 16307 14414 GO:00081…. query_1 TRUE 0.0000043 61 2057 24 0.0116675 0.3934426 GO:0070972 GO:BP protein localization to endoplasmic reticulum 16307 17473 GO:0033365 query_1 TRUE 0.0000047 161 2057 45 0.0218765 0.2795031 GO:0010952 GO:BP positive regulation of peptidase activity 16307 4672 GO:00458…. query_1 TRUE 0.0000047 24 2057 14 0.0068060 0.5833333 GO:0018279 GO:BP protein N-linked glycosylation via asparagine 16307 5661 GO:0006487 query_1 TRUE 0.0000047 24 2057 14 0.0068060 0.5833333 GO:0009124 GO:BP nucleoside monophosphate biosynthetic process 16307 3383 GO:00091…. query_1 TRUE 0.0000047 24 2057 14 0.0068060 0.5833333 GO:1903241 GO:BP U2-type prespliceosome assembly 16307 24062 GO:0000245 query_1 TRUE 0.0000050 21 2057 13 0.0063199 0.6190476 GO:0033119 GO:BP negative regulation of RNA splicing 16307 8513 GO:00083…. query_1 TRUE 0.0000050 126 2057 38 0.0184735 0.3015873 GO:0045727 GO:BP positive regulation of translation 16307 12343 GO:00064…. query_1 TRUE 0.0000055 288 2057 68 0.0330579 0.2361111 GO:0006979 GO:BP response to oxidative stress 16307 2678 GO:0006950 query_1 TRUE 0.0000055 1310 2057 227 0.1103549 0.1732824 GO:0044093 GO:BP positive regulation of molecular function 16307 11613 GO:0065009 query_1 TRUE 0.0000057 232 2057 58 0.0281964 0.2500000 GO:0044403 GO:BP biological process involved in symbiotic interaction 16307 11717 GO:0044419 query_1 TRUE 0.0000062 42 2057 19 0.0092368 0.4523810 GO:0006695 GO:BP cholesterol biosynthetic process 16307 2470 GO:00082…. query_1 TRUE 0.0000062 42 2057 19 0.0092368 0.4523810 GO:1902653 GO:BP secondary alcohol biosynthetic process 16307 23587 GO:00461…. query_1 TRUE 0.0000065 13 2057 10 0.0048614 0.7692308 GO:0006122 GO:BP mitochondrial electron transport, ubiquinol to cytochrome c 16307 2032 GO:00196…. query_1 TRUE 0.0000065 13 2057 10 0.0048614 0.7692308 GO:0007008 GO:BP outer mitochondrial membrane organization 16307 2695 GO:0007006 query_1 TRUE 0.0000065 13 2057 10 0.0048614 0.7692308 GO:0045040 GO:BP protein insertion into mitochondrial outer membrane 16307 12006 GO:00066…. query_1 TRUE 0.0000065 46 2057 20 0.0097229 0.4347826 GO:0016126 GO:BP sterol biosynthetic process 16307 5301 GO:00066…. query_1 TRUE 0.0000067 71 2057 26 0.0126398 0.3661972 GO:0000245 GO:BP spliceosomal complex assembly 16307 73 GO:00003…. query_1 TRUE 0.0000069 80 2057 28 0.0136121 0.3500000 GO:1903312 GO:BP negative regulation of mRNA metabolic process 16307 24115 GO:00160…. query_1 TRUE 0.0000078 85 2057 29 0.0140982 0.3411765 GO:0030433 GO:BP ubiquitin-dependent ERAD pathway 16307 7202 GO:00365…. query_1 TRUE 0.0000078 761 2057 144 0.0700049 0.1892247 GO:0044092 GO:BP negative regulation of molecular function 16307 11612 GO:0065009 query_1 TRUE 0.0000079 99 2057 32 0.0155566 0.3232323 GO:0019080 GO:BP viral gene expression 16307 5899 GO:0016032 query_1 TRUE 0.0000079 373 2057 82 0.0398639 0.2198391 GO:0051656 GO:BP establishment of organelle localization 16307 14740 GO:00512…. query_1 TRUE 0.0000084 154 2057 43 0.0209042 0.2792208 GO:0050792 GO:BP regulation of viral process 16307 14089 GO:00160…. query_1 TRUE 0.0000089 25 2057 14 0.0068060 0.5600000 GO:0006099 GO:BP tricarboxylic acid cycle 16307 2011 GO:00090…. query_1 TRUE 0.0000094 230 2057 57 0.0277103 0.2478261 GO:0043122 GO:BP regulation of I-kappaB kinase/NF-kappaB signaling 16307 11182 GO:00072…. query_1 TRUE 0.0000094 208 2057 53 0.0257657 0.2548077 GO:0031330 GO:BP negative regulation of cellular catabolic process 16307 7556 GO:00098…. query_1 TRUE 0.0000096 247 2057 60 0.0291687 0.2429150 GO:0062197 GO:BP cellular response to chemical stress 16307 16898 GO:00335…. query_1 TRUE 0.0000104 19 2057 12 0.0058337 0.6315789 GO:0006123 GO:BP mitochondrial electron transport, cytochrome c to oxygen 16307 2033 GO:00196…. query_1 TRUE 0.0000104 19 2057 12 0.0058337 0.6315789 GO:0007042 GO:BP lysosomal lumen acidification 16307 2721 GO:00070…. query_1 TRUE 0.0000105 11 2057 9 0.0043753 0.8181818 GO:1904871 GO:BP positive regulation of protein localization to Cajal body 16307 25482 GO:19001…. query_1 TRUE 0.0000105 11 2057 9 0.0043753 0.8181818 GO:0070203 GO:BP regulation of establishment of protein localization to telomere 16307 17027 GO:00702…. query_1 TRUE 0.0000105 11 2057 9 0.0043753 0.8181818 GO:1904869 GO:BP regulation of protein localization to Cajal body 16307 25480 GO:19001…. query_1 TRUE 0.0000142 439 2057 92 0.0447253 0.2095672 GO:0010638 GO:BP positive regulation of organelle organization 16307 4402 GO:00069…. query_1 TRUE 0.0000143 92 2057 30 0.0145843 0.3260870 GO:0042177 GO:BP negative regulation of protein catabolic process 16307 10632 GO:00098…. query_1 TRUE 0.0000159 195 2057 50 0.0243072 0.2564103 GO:2000116 GO:BP regulation of cysteine-type endopeptidase activity 16307 26875 GO:0052548 query_1 TRUE 0.0000163 26 2057 14 0.0068060 0.5384615 GO:1902175 GO:BP regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 16307 23220 GO:00086…. query_1 TRUE 0.0000175 174 2057 46 0.0223627 0.2643678 GO:0043123 GO:BP positive regulation of I-kappaB kinase/NF-kappaB signaling 16307 11183 GO:00072…. query_1 TRUE 0.0000181 1249 2057 215 0.1045211 0.1721377 GO:0031399 GO:BP regulation of protein modification process 16307 7591 GO:00362…. query_1 TRUE 0.0000196 23 2057 13 0.0063199 0.5652174 GO:0035751 GO:BP regulation of lysosomal lumen pH 16307 9771 GO:00070…. query_1 TRUE 0.0000199 258 2057 61 0.0296548 0.2364341 GO:0007249 GO:BP I-kappaB kinase/NF-kappaB signaling 16307 2868 GO:0035556 query_1 TRUE 0.0000201 84 2057 28 0.0136121 0.3333333 GO:0045185 GO:BP maintenance of protein location 16307 12078 GO:00081…. query_1 TRUE 0.0000227 401 2057 85 0.0413223 0.2119701 GO:0031400 GO:BP negative regulation of protein modification process 16307 7592 GO:00313…. query_1 TRUE 0.0000232 62 2057 23 0.0111813 0.3709677 GO:0048524 GO:BP positive regulation of viral process 16307 13628 GO:00160…. query_1 TRUE 0.0000274 193 2057 49 0.0238211 0.2538860 GO:0000070 GO:BP mitotic sister chromatid segregation 16307 25 GO:00008…. query_1 TRUE 0.0000281 67 2057 24 0.0116675 0.3582090 GO:1902600 GO:BP proton transmembrane transport 16307 23539 GO:00986…. query_1 TRUE 0.0000287 177 2057 46 0.0223627 0.2598870 GO:0006364 GO:BP rRNA processing 16307 2201 GO:00160…. query_1 TRUE 0.0000288 27 2057 14 0.0068060 0.5185185 GO:1901798 GO:BP positive regulation of signal transduction by p53 class mediator 16307 22872 GO:00723…. query_1 TRUE 0.0000292 38 2057 17 0.0082645 0.4473684 GO:0008631 GO:BP intrinsic apoptotic signaling pathway in response to oxidative stress 16307 3310 GO:00364…. query_1 TRUE 0.0000305 42 2057 18 0.0087506 0.4285714 GO:0090199 GO:BP regulation of release of cytochrome c from mitochondria 16307 19247 GO:00018…. query_1 TRUE 0.0000344 268 2057 62 0.0301410 0.2313433 GO:0140014 GO:BP mitotic nuclear division 16307 20857 GO:00002…. query_1 TRUE 0.0000347 12 2057 9 0.0043753 0.7500000 GO:0070202 GO:BP regulation of establishment of protein localization to chromosome 16307 17026 GO:00701…. query_1 TRUE 0.0000347 12 2057 9 0.0043753 0.7500000 GO:1904867 GO:BP protein localization to Cajal body 16307 25478 GO:1903405 query_1 TRUE 0.0000347 12 2057 9 0.0043753 0.7500000 GO:1903405 GO:BP protein localization to nuclear body 16307 24202 GO:1990173 query_1 TRUE 0.0000369 730 2057 136 0.0661157 0.1863014 GO:0061024 GO:BP membrane organization 16307 16108 GO:0016043 query_1 TRUE 0.0000372 292 2057 66 0.0320856 0.2260274 GO:0016236 GO:BP macroautophagy 16307 5336 GO:0006914 query_1 TRUE 0.0000421 844 2057 153 0.0743802 0.1812796 GO:0051130 GO:BP positive regulation of cellular component organization 16307 14359 GO:00160…. query_1 TRUE 0.0000466 97 2057 30 0.0145843 0.3092784 GO:0007006 GO:BP mitochondrial membrane organization 16307 2693 GO:00070…. query_1 TRUE 0.0000466 288 2057 65 0.0315994 0.2256944 GO:0048193 GO:BP Golgi vesicle transport 16307 13388 GO:0016192 query_1 TRUE 0.0000468 236 2057 56 0.0272241 0.2372881 GO:0000819 GO:BP sister chromatid segregation 16307 253 GO:00512…. query_1 TRUE 0.0000473 18 2057 11 0.0053476 0.6111111 GO:0019081 GO:BP viral translation 16307 5900 GO:00160…. query_1 TRUE 0.0000474 458 2057 93 0.0452115 0.2030568 GO:0044283 GO:BP small molecule biosynthetic process 16307 11664 GO:00090…. query_1 TRUE 0.0000494 143 2057 39 0.0189596 0.2727273 GO:0051701 GO:BP biological process involved in interaction with host 16307 14774 GO:0044403 query_1 TRUE 0.0000503 566 2057 110 0.0534759 0.1943463 GO:0051129 GO:BP negative regulation of cellular component organization 16307 14358 GO:00160…. query_1 TRUE 0.0000542 1966 2057 314 0.1526495 0.1597152 GO:0070887 GO:BP cellular response to chemical stimulus 16307 17415 GO:00422…. query_1 TRUE 0.0000544 962 2057 170 0.0826446 0.1767152 GO:0043085 GO:BP positive regulation of catalytic activity 16307 11157 GO:00440…. query_1 TRUE 0.0000565 198 2057 49 0.0238211 0.2474747 GO:1903050 GO:BP regulation of proteolysis involved in protein catabolic process 16307 23919 GO:00301…. query_1 TRUE 0.0000566 2197 2057 346 0.1682061 0.1574875 GO:0035556 GO:BP intracellular signal transduction 16307 9639 GO:0007165 query_1 TRUE 0.0000582 113 2057 33 0.0160428 0.2920354 GO:0044000 GO:BP movement in host 16307 11567 GO:0051701 query_1 TRUE 0.0000692 2521 2057 390 0.1895965 0.1547005 GO:0031325 GO:BP positive regulation of cellular metabolic process 16307 7551 GO:00098…. query_1 TRUE 0.0000724 109 2057 32 0.0155566 0.2935780 GO:0071453 GO:BP cellular response to oxygen levels 16307 17763 GO:00704…. query_1 TRUE 0.0000771 135 2057 37 0.0179874 0.2740741 GO:1903900 GO:BP regulation of viral life cycle 16307 24630 GO:00190…. query_1 TRUE 0.0000772 178 2057 45 0.0218765 0.2528090 GO:0045732 GO:BP positive regulation of protein catabolic process 16307 12347 GO:00098…. query_1 TRUE 0.0000772 610 2057 116 0.0563928 0.1901639 GO:0010243 GO:BP response to organonitrogen compound 16307 4119 GO:00100…. query_1 TRUE 0.0000782 151 2057 40 0.0194458 0.2649007 GO:0010950 GO:BP positive regulation of endopeptidase activity 16307 4670 GO:00109…. query_1 TRUE 0.0000787 470 2057 94 0.0456976 0.2000000 GO:0043086 GO:BP negative regulation of catalytic activity 16307 11158 GO:00440…. query_1 TRUE 0.0000789 206 2057 50 0.0243072 0.2427184 GO:0034599 GO:BP cellular response to oxidative stress 16307 9189 GO:00069…. query_1 TRUE 0.0000797 246 2057 57 0.0277103 0.2317073 GO:0072659 GO:BP protein localization to plasma membrane 16307 18586 GO:00726…. query_1 TRUE 0.0000817 125 2057 35 0.0170151 0.2800000 GO:0000302 GO:BP response to reactive oxygen species 16307 93 GO:00069…. query_1 TRUE 0.0000878 241 2057 56 0.0272241 0.2323651 GO:0033044 GO:BP regulation of chromosome organization 16307 8469 GO:00330…. query_1 TRUE 0.0000915 1328 2057 222 0.1079242 0.1671687 GO:0051049 GO:BP regulation of transport 16307 14302 GO:00068…. query_1 TRUE 0.0000915 13 2057 9 0.0043753 0.6923077 GO:1904816 GO:BP positive regulation of protein localization to chromosome, telomeric region 16307 25434 GO:00701…. query_1 TRUE 0.0000915 45 2057 18 0.0087506 0.4000000 GO:0046824 GO:BP positive regulation of nucleocytoplasmic transport 16307 13177 GO:00069…. query_1 TRUE 0.0000915 306 2057 67 0.0325717 0.2189542 GO:0010639 GO:BP negative regulation of organelle organization 16307 4403 GO:00069…. query_1 TRUE 0.0000960 58 2057 21 0.0102090 0.3620690 GO:0032507 GO:BP maintenance of protein location in cell 16307 8077 GO:00451…. query_1 TRUE 0.0001018 1240 2057 209 0.1016043 0.1685484 GO:0042592 GO:BP homeostatic process 16307 10883 GO:0008150 query_1 TRUE 0.0001039 505 2057 99 0.0481283 0.1960396 GO:0045859 GO:BP regulation of protein kinase activity 16307 12447 GO:00019…. query_1 TRUE 0.0001101 5908 2057 837 0.4069033 0.1416723 GO:0019222 GO:BP regulation of metabolic process 16307 5935 GO:00081…. query_1 TRUE 0.0001197 170 2057 43 0.0209042 0.2529412 GO:0061136 GO:BP regulation of proteasomal protein catabolic process 16307 16216 GO:00104…. query_1 TRUE 0.0001231 394 2057 81 0.0393777 0.2055838 GO:0007015 GO:BP actin filament organization 16307 2699 GO:00300…. query_1 TRUE 0.0001256 30 2057 14 0.0068060 0.4666667 GO:0070979 GO:BP protein K11-linked ubiquitination 16307 17477 GO:0000209 query_1 TRUE 0.0001256 30 2057 14 0.0068060 0.4666667 GO:0007035 GO:BP vacuolar acidification 16307 2715 GO:0051452 query_1 TRUE 0.0001269 87 2057 27 0.0131259 0.3103448 GO:0007032 GO:BP endosome organization 16307 2712 GO:00102…. query_1 TRUE 0.0001287 46 2057 18 0.0087506 0.3913043 GO:0032527 GO:BP protein exit from endoplasmic reticulum 16307 8086 GO:0006886 query_1 TRUE 0.0001361 34 2057 15 0.0072922 0.4411765 GO:0090151 GO:BP establishment of protein localization to mitochondrial membrane 16307 19204 GO:00070…. query_1 TRUE 0.0001391 328 2057 70 0.0340301 0.2134146 GO:0009615 GO:BP response to virus 16307 3634 GO:0051707 query_1 TRUE 0.0001402 310 2057 67 0.0325717 0.2161290 GO:1902903 GO:BP regulation of supramolecular fiber organization 16307 23782 GO:00511…. query_1 TRUE 0.0001501 1213 2057 204 0.0991736 0.1681781 GO:0080134 GO:BP regulation of response to stress 16307 18942 GO:00069…. query_1 TRUE 0.0001728 276 2057 61 0.0296548 0.2210145 GO:1990778 GO:BP protein localization to cell periphery 16307 26682 GO:0008104 query_1 TRUE 0.0001739 20 2057 11 0.0053476 0.5500000 GO:0046685 GO:BP response to arsenic-containing substance 16307 13103 GO:0042221 query_1 TRUE 0.0001761 11 2057 8 0.0038892 0.7272727 GO:0009263 GO:BP deoxyribonucleotide biosynthetic process 16307 3520 GO:00091…. query_1 TRUE 0.0001761 11 2057 8 0.0038892 0.7272727 GO:0046385 GO:BP deoxyribose phosphate biosynthetic process 16307 12896 GO:00196…. query_1 TRUE 0.0001761 11 2057 8 0.0038892 0.7272727 GO:0061795 GO:BP Golgi lumen acidification 16307 16696 GO:0051452 query_1 TRUE 0.0001761 11 2057 8 0.0038892 0.7272727 GO:0070934 GO:BP CRD-mediated mRNA stabilization 16307 17443 GO:0048255 query_1 TRUE 0.0001761 423 2057 85 0.0413223 0.2009456 GO:0022411 GO:BP cellular component disassembly 16307 6999 GO:0016043 query_1 TRUE 0.0001761 11 2057 8 0.0038892 0.7272727 GO:0034975 GO:BP protein folding in endoplasmic reticulum 16307 9267 GO:0006457 query_1 TRUE 0.0001761 74 2057 24 0.0116675 0.3243243 GO:1905897 GO:BP regulation of response to endoplasmic reticulum stress 16307 26370 GO:00349…. query_1 TRUE 0.0001761 11 2057 8 0.0038892 0.7272727 GO:0009265 GO:BP 2’-deoxyribonucleotide biosynthetic process 16307 3522 GO:00092…. query_1 TRUE 0.0001761 11 2057 8 0.0038892 0.7272727 GO:0075522 GO:BP IRES-dependent viral translational initiation 16307 18878 GO:00160…. query_1 TRUE 0.0001996 17 2057 10 0.0048614 0.5882353 GO:0071243 GO:BP cellular response to arsenic-containing substance 16307 17574 GO:00466…. query_1 TRUE 0.0001996 39 2057 16 0.0077783 0.4102564 GO:1990000 GO:BP amyloid fibril formation 16307 26427 GO:00195…. query_1 TRUE 0.0002058 260 2057 58 0.0281964 0.2230769 GO:0051169 GO:BP nuclear transport 16307 14397 GO:0046907 query_1 TRUE 0.0002058 260 2057 58 0.0281964 0.2230769 GO:0006913 GO:BP nucleocytoplasmic transport 16307 2634 GO:0051169 query_1 TRUE 0.0002077 14 2057 9 0.0043753 0.6428571 GO:1990173 GO:BP protein localization to nucleoplasm 16307 26486 GO:0034504 query_1 TRUE 0.0002086 482 2057 94 0.0456976 0.1950207 GO:0051640 GO:BP organelle localization 16307 14724 GO:0051179 query_1 TRUE 0.0002101 152 2057 39 0.0189596 0.2565789 GO:1902850 GO:BP microtubule cytoskeleton organization involved in mitosis 16307 23739 GO:00002…. query_1 TRUE 0.0002150 457 2057 90 0.0437530 0.1969365 GO:0009896 GO:BP positive regulation of catabolic process 16307 3850 GO:00090…. query_1 TRUE 0.0002298 24 2057 12 0.0058337 0.5000000 GO:0009126 GO:BP purine nucleoside monophosphate metabolic process 16307 3385 GO:0009123 query_1 TRUE 0.0002318 309 2057 66 0.0320856 0.2135922 GO:0010506 GO:BP regulation of autophagy 16307 4291 GO:00069…. query_1 TRUE 0.0002318 778 2057 139 0.0675741 0.1786632 GO:0019752 GO:BP carboxylic acid metabolic process 16307 6401 GO:0043436 query_1 TRUE 0.0002319 226 2057 52 0.0252795 0.2300885 GO:0051348 GO:BP negative regulation of transferase activity 16307 14527 GO:00430…. query_1 TRUE 0.0002393 600 2057 112 0.0544482 0.1866667 GO:0043549 GO:BP regulation of kinase activity 16307 11416 GO:00423…. query_1 TRUE 0.0002559 693 2057 126 0.0612543 0.1818182 GO:1901698 GO:BP response to nitrogen compound 16307 22778 GO:0042221 query_1 TRUE 0.0002607 71 2057 23 0.0111813 0.3239437 GO:0031397 GO:BP negative regulation of protein ubiquitination 16307 7589 GO:00165…. query_1 TRUE 0.0002820 40 2057 16 0.0077783 0.4000000 GO:0032781 GO:BP positive regulation of ATP-dependent activity 16307 8285 GO:00434…. query_1 TRUE 0.0002820 40 2057 16 0.0077783 0.4000000 GO:0045454 GO:BP cell redox homeostasis 16307 12157 GO:0019725 query_1 TRUE 0.0002878 385 2057 78 0.0379193 0.2025974 GO:0043068 GO:BP positive regulation of programmed cell death 16307 11153 GO:00109…. query_1 TRUE 0.0002879 32 2057 14 0.0068060 0.4375000 GO:0051204 GO:BP protein insertion into mitochondrial membrane 16307 14413 GO:00068…. query_1 TRUE 0.0002987 21 2057 11 0.0053476 0.5238095 GO:0048026 GO:BP positive regulation of mRNA splicing, via spliceosome 16307 13293 GO:00003…. query_1 TRUE 0.0003072 392 2057 79 0.0384054 0.2015306 GO:0009611 GO:BP response to wounding 16307 3632 GO:0006950 query_1 TRUE 0.0003089 67 2057 22 0.0106952 0.3283582 GO:2000573 GO:BP positive regulation of DNA biosynthetic process 16307 27304 GO:00105…. query_1 TRUE 0.0003089 67 2057 22 0.0106952 0.3283582 GO:0036473 GO:BP cell death in response to oxidative stress 16307 10203 GO:00082…. query_1 TRUE 0.0003236 9 2057 7 0.0034030 0.7777778 GO:0046037 GO:BP GMP metabolic process 16307 12590 GO:00091…. query_1 TRUE 0.0003632 438 2057 86 0.0418085 0.1963470 GO:0010942 GO:BP positive regulation of cell death 16307 4664 GO:00082…. query_1 TRUE 0.0003730 118 2057 32 0.0155566 0.2711864 GO:1903322 GO:BP positive regulation of protein modification by small protein conjugation or removal 16307 24125 GO:00314…. query_1 TRUE 0.0003730 25 2057 12 0.0058337 0.4800000 GO:0034063 GO:BP stress granule assembly 16307 8876 GO:0140694 query_1 TRUE 0.0003845 54 2057 19 0.0092368 0.3518519 GO:0033619 GO:BP membrane protein proteolysis 16307 8803 GO:0006508 query_1 TRUE 0.0003945 68 2057 22 0.0106952 0.3235294 GO:0006487 GO:BP protein N-linked glycosylation 16307 2285 GO:0006486 query_1 TRUE 0.0003945 41 2057 16 0.0077783 0.3902439 GO:0006984 GO:BP ER-nucleus signaling pathway 16307 2681 GO:0007165 query_1 TRUE 0.0003945 68 2057 22 0.0106952 0.3235294 GO:0042274 GO:BP ribosomal small subunit biogenesis 16307 10699 GO:00226…. query_1 TRUE 0.0004021 433 2057 85 0.0413223 0.1963048 GO:1902532 GO:BP negative regulation of intracellular signal transduction 16307 23503 GO:00099…. query_1 TRUE 0.0004044 162 2057 40 0.0194458 0.2469136 GO:0043281 GO:BP regulation of cysteine-type endopeptidase activity involved in apoptotic process 16307 11247 GO:2000116 query_1 TRUE 0.0004111 29 2057 13 0.0063199 0.4482759 GO:0009161 GO:BP ribonucleoside monophosphate metabolic process 16307 3419 GO:0009123 query_1 TRUE 0.0004128 73 2057 23 0.0111813 0.3150685 GO:0006900 GO:BP vesicle budding from membrane 16307 2625 GO:00160…. query_1 TRUE 0.0004194 15 2057 9 0.0043753 0.6000000 GO:1905906 GO:BP regulation of amyloid fibril formation 16307 26379 GO:00512…. query_1 TRUE 0.0004194 15 2057 9 0.0043753 0.6000000 GO:1904814 GO:BP regulation of protein localization to chromosome, telomeric region 16307 25432 GO:00328…. query_1 TRUE 0.0004194 12 2057 8 0.0038892 0.6666667 GO:0048388 GO:BP endosomal lumen acidification 16307 13543 GO:00070…. query_1 TRUE 0.0004194 33 2057 14 0.0068060 0.4242424 GO:0033120 GO:BP positive regulation of RNA splicing 16307 8514 GO:00083…. query_1 TRUE 0.0004194 15 2057 9 0.0043753 0.6000000 GO:0009127 GO:BP purine nucleoside monophosphate biosynthetic process 16307 3386 GO:00091…. query_1 TRUE 0.0004194 15 2057 9 0.0043753 0.6000000 GO:2000767 GO:BP positive regulation of cytoplasmic translation 16307 27469 GO:00021…. query_1 TRUE 0.0004194 12 2057 8 0.0038892 0.6666667 GO:0061684 GO:BP chaperone-mediated autophagy 16307 16639 GO:00069…. query_1 TRUE 0.0004194 12 2057 8 0.0038892 0.6666667 GO:1905907 GO:BP negative regulation of amyloid fibril formation 16307 26380 GO:00512…. query_1 TRUE 0.0004241 285 2057 61 0.0296548 0.2140351 GO:0051604 GO:BP protein maturation 16307 14692 GO:00104…. query_1 TRUE 0.0004241 802 2057 141 0.0685464 0.1758105 GO:0043436 GO:BP oxoacid metabolic process 16307 11340 GO:0006082 query_1 TRUE 0.0004241 50 2057 18 0.0087506 0.3600000 GO:1903201 GO:BP regulation of oxidative stress-induced cell death 16307 24027 GO:00109…. query_1 TRUE 0.0004241 371 2057 75 0.0364609 0.2021563 GO:0043065 GO:BP positive regulation of apoptotic process 16307 11150 GO:00069…. query_1 TRUE 0.0004739 256 2057 56 0.0272241 0.2187500 GO:0046394 GO:BP carboxylic acid biosynthetic process 16307 12903 GO:00160…. query_1 TRUE 0.0004795 125 2057 33 0.0160428 0.2640000 GO:0007052 GO:BP mitotic spindle organization 16307 2726 GO:00070…. query_1 TRUE 0.0004871 104 2057 29 0.0140982 0.2788462 GO:0034614 GO:BP cellular response to reactive oxygen species 16307 9196 GO:00003…. query_1 TRUE 0.0004930 158 2057 39 0.0189596 0.2468354 GO:0071897 GO:BP DNA biosynthetic process 16307 18061 GO:00062…. query_1 TRUE 0.0005218 89 2057 26 0.0126398 0.2921348 GO:1901796 GO:BP regulation of signal transduction by p53 class mediator 16307 22870 GO:00723…. query_1 TRUE 0.0005226 84 2057 25 0.0121536 0.2976190 GO:2001235 GO:BP positive regulation of apoptotic signaling pathway 16307 27882 GO:00099…. query_1 TRUE 0.0005611 110 2057 30 0.0145843 0.2727273 GO:2000278 GO:BP regulation of DNA biosynthetic process 16307 27031 GO:00105…. query_1 TRUE 0.0005700 444 2057 86 0.0418085 0.1936937 GO:0051347 GO:BP positive regulation of transferase activity 16307 14526 GO:00430…. query_1 TRUE 0.0005810 331 2057 68 0.0330579 0.2054381 GO:0042060 GO:BP wound healing 16307 10569 GO:0009611 query_1 TRUE 0.0005857 258 2057 56 0.0272241 0.2170543 GO:0016053 GO:BP organic acid biosynthetic process 16307 5241 GO:00060…. query_1 TRUE 0.0006035 30 2057 13 0.0063199 0.4333333 GO:0050685 GO:BP positive regulation of mRNA processing 16307 14043 GO:00063…. query_1 TRUE 0.0006035 100 2057 28 0.0136121 0.2800000 GO:1902652 GO:BP secondary alcohol metabolic process 16307 23586 GO:0006066 query_1 TRUE 0.0006302 75 2057 23 0.0111813 0.3066667 GO:0043648 GO:BP dicarboxylic acid metabolic process 16307 11490 GO:0019752 query_1 TRUE 0.0006302 75 2057 23 0.0111813 0.3066667 GO:0046822 GO:BP regulation of nucleocytoplasmic transport 16307 13175 GO:00069…. query_1 TRUE 0.0006367 56 2057 19 0.0092368 0.3392857 GO:0007080 GO:BP mitotic metaphase plate congression 16307 2748 GO:00000…. query_1 TRUE 0.0006378 19 2057 10 0.0048614 0.5263158 GO:1904666 GO:BP regulation of ubiquitin protein ligase activity 16307 25305 GO:0051438 query_1 TRUE 0.0006487 5 2057 5 0.0024307 1.0000000 GO:0075525 GO:BP viral translational termination-reinitiation 16307 18881 GO:00160…. query_1 TRUE 0.0006716 810 2057 141 0.0685464 0.1740741 GO:0006082 GO:BP organic acid metabolic process 16307 1999 GO:00442…. query_1 TRUE 0.0006940 2486 2057 376 0.1827905 0.1512470 GO:0009966 GO:BP regulation of signal transduction 16307 3898 GO:00071…. query_1 TRUE 0.0007449 52 2057 18 0.0087506 0.3461538 GO:0006890 GO:BP retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 16307 2617 GO:0048193 query_1 TRUE 0.0007466 96 2057 27 0.0131259 0.2812500 GO:0045931 GO:BP positive regulation of mitotic cell cycle 16307 12501 GO:00002…. query_1 TRUE 0.0007652 71 2057 22 0.0106952 0.3098592 GO:0010822 GO:BP positive regulation of mitochondrion organization 16307 4566 GO:00070…. query_1 TRUE 0.0007849 81 2057 24 0.0116675 0.2962963 GO:1903321 GO:BP negative regulation of protein modification by small protein conjugation or removal 16307 24124 GO:00314…. query_1 TRUE 0.0007887 16 2057 9 0.0043753 0.5625000 GO:0000028 GO:BP ribosomal small subunit assembly 16307 14 GO:00226…. query_1 TRUE 0.0007887 16 2057 9 0.0043753 0.5625000 GO:0048025 GO:BP negative regulation of mRNA splicing, via spliceosome 16307 13292 GO:00003…. query_1 TRUE 0.0007887 23 2057 11 0.0053476 0.4782609 GO:0009167 GO:BP purine ribonucleoside monophosphate metabolic process 16307 3425 GO:00091…. query_1 TRUE 0.0008104 57 2057 19 0.0092368 0.3333333 GO:0034033 GO:BP purine nucleoside bisphosphate biosynthetic process 16307 8863 GO:00338…. query_1 TRUE 0.0008104 4978 2057 706 0.3432183 0.1418240 GO:0051171 GO:BP regulation of nitrogen compound metabolic process 16307 14399 GO:00068…. query_1 TRUE 0.0008104 57 2057 19 0.0092368 0.3333333 GO:0034030 GO:BP ribonucleoside bisphosphate biosynthetic process 16307 8860 GO:00338…. query_1 TRUE 0.0008104 57 2057 19 0.0092368 0.3333333 GO:0033866 GO:BP nucleoside bisphosphate biosynthetic process 16307 8850 GO:00338…. query_1 TRUE 0.0008104 1849 2057 288 0.1400097 0.1557599 GO:0031324 GO:BP negative regulation of cellular metabolic process 16307 7550 GO:00098…. query_1 TRUE 0.0008104 57 2057 19 0.0092368 0.3333333 GO:1900407 GO:BP regulation of cellular response to oxidative stress 16307 21686 GO:00345…. query_1 TRUE 0.0008407 2155 2057 330 0.1604278 0.1531323 GO:0065008 GO:BP regulation of biological quality 16307 16928 GO:0065007 query_1 TRUE 0.0008417 35 2057 14 0.0068060 0.4000000 GO:0072595 GO:BP maintenance of protein localization in organelle 16307 18565 GO:00325…. query_1 TRUE 0.0008434 214 2057 48 0.0233350 0.2242991 GO:0016072 GO:BP rRNA metabolic process 16307 5256 GO:0034660 query_1 TRUE 0.0008519 220 2057 49 0.0238211 0.2227273 GO:0006402 GO:BP mRNA catabolic process 16307 2226 GO:00064…. query_1 TRUE 0.0008519 27 2057 12 0.0058337 0.4444444 GO:0070199 GO:BP establishment of protein localization to chromosome 16307 17023 GO:00345…. query_1 TRUE 0.0008777 13 2057 8 0.0038892 0.6153846 GO:1905048 GO:BP regulation of metallopeptidase activity 16307 25646 GO:0052547 query_1 TRUE 0.0009085 330 2057 67 0.0325717 0.2030303 GO:0043254 GO:BP regulation of protein-containing complex assembly 16307 11233 GO:00440…. query_1 TRUE 0.0009150 203 2057 46 0.0223627 0.2266010 GO:0070997 GO:BP neuron death 16307 17488 GO:0008219 query_1 TRUE 0.0009379 146 2057 36 0.0175012 0.2465753 GO:0072331 GO:BP signal transduction by p53 class mediator 16307 18456 GO:0035556 query_1 TRUE 0.0010131 716 2057 126 0.0612543 0.1759777 GO:0097435 GO:BP supramolecular fiber organization 16307 19838 GO:0016043 query_1 TRUE 0.0010610 216 2057 48 0.0233350 0.2222222 GO:0110053 GO:BP regulation of actin filament organization 16307 20589 GO:00070…. query_1 TRUE 0.0010610 20 2057 10 0.0048614 0.5000000 GO:0009156 GO:BP ribonucleoside monophosphate biosynthetic process 16307 3415 GO:00091…. query_1 TRUE 0.0011114 49 2057 17 0.0082645 0.3469388 GO:0051881 GO:BP regulation of mitochondrial membrane potential 16307 14840 GO:0042391 query_1 TRUE 0.0011114 49 2057 17 0.0082645 0.3469388 GO:0051438 GO:BP regulation of ubiquitin-protein transferase activity 16307 14567 GO:0051338 query_1 TRUE 0.0011240 88 2057 25 0.0121536 0.2840909 GO:1903076 GO:BP regulation of protein localization to plasma membrane 16307 23944 GO:00726…. query_1 TRUE 0.0011357 68 2057 21 0.0102090 0.3088235 GO:0051310 GO:BP metaphase plate congression 16307 14493 GO:00513…. query_1 TRUE 0.0011383 779 2057 135 0.0656296 0.1732991 GO:0051336 GO:BP regulation of hydrolase activity 16307 14515 GO:0050790 query_1 TRUE 0.0011502 2739 2057 408 0.1983471 0.1489595 GO:0023051 GO:BP regulation of signaling 16307 7036 GO:00230…. query_1 TRUE 0.0011730 36 2057 14 0.0068060 0.3888889 GO:1904358 GO:BP positive regulation of telomere maintenance via telomere lengthening 16307 25035 GO:00108…. query_1 TRUE 0.0012171 24 2057 11 0.0053476 0.4583333 GO:0035336 GO:BP long-chain fatty-acyl-CoA metabolic process 16307 9513 GO:0035337 query_1 TRUE 0.0012486 32 2057 13 0.0063199 0.4062500 GO:0022612 GO:BP gland morphogenesis 16307 7016 GO:00098…. query_1 TRUE 0.0012600 340 2057 68 0.0330579 0.2000000 GO:0045936 GO:BP negative regulation of phosphate metabolic process 16307 12506 GO:00067…. query_1 TRUE 0.0012686 28 2057 12 0.0058337 0.4285714 GO:0045116 GO:BP protein neddylation 16307 12050 GO:0032446 query_1 TRUE 0.0013006 94 2057 26 0.0126398 0.2765957 GO:0071456 GO:BP cellular response to hypoxia 16307 17766 GO:00016…. query_1 TRUE 0.0013106 59 2057 19 0.0092368 0.3220339 GO:0072332 GO:BP intrinsic apoptotic signaling pathway by p53 class mediator 16307 18457 GO:00723…. query_1 TRUE 0.0013237 297 2057 61 0.0296548 0.2053872 GO:0098813 GO:BP nuclear chromosome segregation 16307 20093 GO:0007059 query_1 TRUE 0.0013670 64 2057 20 0.0097229 0.3125000 GO:0043462 GO:BP regulation of ATP-dependent activity 16307 11360 GO:0065009 query_1 TRUE 0.0013670 341 2057 68 0.0330579 0.1994135 GO:0010563 GO:BP negative regulation of phosphorus metabolic process 16307 4333 GO:00067…. query_1 TRUE 0.0013756 17 2057 9 0.0043753 0.5294118 GO:0070200 GO:BP establishment of protein localization to telomere 16307 17024 GO:00701…. query_1 TRUE 0.0014391 41 2057 15 0.0072922 0.3658537 GO:0010823 GO:BP negative regulation of mitochondrion organization 16307 4567 GO:00070…. query_1 TRUE 0.0014391 41 2057 15 0.0072922 0.3658537 GO:0051452 GO:BP intracellular pH reduction 16307 14575 GO:0051453 query_1 TRUE 0.0014391 41 2057 15 0.0072922 0.3658537 GO:0006509 GO:BP membrane protein ectodomain proteolysis 16307 2300 GO:0033619 query_1 TRUE 0.0015546 111 2057 29 0.0140982 0.2612613 GO:0050657 GO:BP nucleic acid transport 16307 14024 GO:0015931 query_1 TRUE 0.0015546 111 2057 29 0.0140982 0.2612613 GO:0050658 GO:BP RNA transport 16307 14025 GO:00506…. query_1 TRUE 0.0016278 8 2057 6 0.0029169 0.7500000 GO:0036261 GO:BP 7-methylguanosine cap hypermethylation 16307 10098 GO:00015…. query_1 TRUE 0.0017057 14 2057 8 0.0038892 0.5714286 GO:0009168 GO:BP purine ribonucleoside monophosphate biosynthetic process 16307 3426 GO:00091…. query_1 TRUE 0.0017285 75 2057 22 0.0106952 0.2933333 GO:0000380 GO:BP alternative mRNA splicing, via spliceosome 16307 120 GO:0000398 query_1 TRUE 0.0017285 70 2057 21 0.0102090 0.3000000 GO:0006278 GO:BP RNA-templated DNA biosynthetic process 16307 2151 GO:0071897 query_1 TRUE 0.0017285 70 2057 21 0.0102090 0.3000000 GO:0007004 GO:BP telomere maintenance via telomerase 16307 2691 GO:00062…. query_1 TRUE 0.0017510 33 2057 13 0.0063199 0.3939394 GO:0032212 GO:BP positive regulation of telomere maintenance via telomerase 16307 7865 GO:00070…. query_1 TRUE 0.0018006 168 2057 39 0.0189596 0.2321429 GO:0031334 GO:BP positive regulation of protein-containing complex assembly 16307 7559 GO:00432…. query_1 TRUE 0.0018070 421 2057 80 0.0388916 0.1900238 GO:0007346 GO:BP regulation of mitotic cell cycle 16307 2942 GO:00002…. query_1 TRUE 0.0018342 25 2057 11 0.0053476 0.4400000 GO:0046949 GO:BP fatty-acyl-CoA biosynthetic process 16307 13256 GO:00353…. query_1 TRUE 0.0018416 174 2057 40 0.0194458 0.2298851 GO:0007051 GO:BP spindle organization 16307 2725 GO:00002…. query_1 TRUE 0.0019182 42 2057 15 0.0072922 0.3571429 GO:0071616 GO:BP acyl-CoA biosynthetic process 16307 17879 GO:00066…. query_1 TRUE 0.0019182 42 2057 15 0.0072922 0.3571429 GO:0035384 GO:BP thioester biosynthetic process 16307 9546 GO:00353…. query_1 TRUE 0.0019182 91 2057 25 0.0121536 0.2747253 GO:0008203 GO:BP cholesterol metabolic process 16307 3218 GO:00161…. query_1 TRUE 0.0019925 210 2057 46 0.0223627 0.2190476 GO:0045861 GO:BP negative regulation of proteolysis 16307 12449 GO:00065…. query_1 TRUE 0.0020527 102 2057 27 0.0131259 0.2647059 GO:0035967 GO:BP cellular response to topologically incorrect protein 16307 9929 GO:00335…. query_1 TRUE 0.0020924 2752 2057 407 0.1978610 0.1478924 GO:0010646 GO:BP regulation of cell communication 16307 4410 GO:00071…. query_1 TRUE 0.0020924 265 2057 55 0.0267380 0.2075472 GO:0006401 GO:BP RNA catabolic process 16307 2225 GO:00160…. query_1 TRUE 0.0021092 124 2057 31 0.0150705 0.2500000 GO:1903313 GO:BP positive regulation of mRNA metabolic process 16307 24116 GO:00160…. query_1 TRUE 0.0021092 5443 2057 761 0.3699562 0.1398126 GO:0060255 GO:BP regulation of macromolecule metabolic process 16307 15399 GO:00192…. query_1 TRUE 0.0021092 777 2057 133 0.0646573 0.1711712 GO:0044087 GO:BP regulation of cellular component biogenesis 16307 11607 GO:00440…. query_1 TRUE 0.0021545 97 2057 26 0.0126398 0.2680412 GO:0036294 GO:BP cellular response to decreased oxygen levels 16307 10123 GO:00362…. query_1 TRUE 0.0021588 38 2057 14 0.0068060 0.3684211 GO:0035337 GO:BP fatty-acyl-CoA metabolic process 16307 9514 GO:00066…. query_1 TRUE 0.0021588 38 2057 14 0.0068060 0.3684211 GO:0000387 GO:BP spliceosomal snRNP assembly 16307 122 GO:00003…. query_1 TRUE 0.0021840 1430 2057 226 0.1098687 0.1580420 GO:0007049 GO:BP cell cycle 16307 2724 GO:0009987 query_1 TRUE 0.0022211 602 2057 107 0.0520175 0.1777409 GO:0019725 GO:BP cellular homeostasis 16307 6383 GO:00099…. query_1 TRUE 0.0022646 147 2057 35 0.0170151 0.2380952 GO:2000058 GO:BP regulation of ubiquitin-dependent protein catabolic process 16307 26818 GO:00065…. query_1 TRUE 0.0022775 18 2057 9 0.0043753 0.5000000 GO:0035338 GO:BP long-chain fatty-acyl-CoA biosynthetic process 16307 9515 GO:00353…. query_1 TRUE 0.0022775 18 2057 9 0.0043753 0.5000000 GO:0050686 GO:BP negative regulation of mRNA processing 16307 14044 GO:00063…. query_1 TRUE 0.0022775 18 2057 9 0.0043753 0.5000000 GO:1902176 GO:BP negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 16307 23221 GO:00086…. query_1 TRUE 0.0023212 52 2057 17 0.0082645 0.3269231 GO:0052372 GO:BP modulation by symbiont of entry into host 16307 15027 GO:00439…. query_1 TRUE 0.0023212 52 2057 17 0.0082645 0.3269231 GO:0033047 GO:BP regulation of mitotic sister chromatid segregation 16307 8472 GO:00000…. query_1 TRUE 0.0023212 52 2057 17 0.0082645 0.3269231 GO:0070059 GO:BP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 16307 16933 GO:00349…. query_1 TRUE 0.0024211 82 2057 23 0.0111813 0.2804878 GO:0045069 GO:BP regulation of viral genome replication 16307 12031 GO:00190…. query_1 TRUE 0.0024211 114 2057 29 0.0140982 0.2543860 GO:0051236 GO:BP establishment of RNA localization 16307 14438 GO:00064…. query_1 TRUE 0.0024457 57 2057 18 0.0087506 0.3157895 GO:0043903 GO:BP regulation of biological process involved in symbiotic interaction 16307 11518 GO:00444…. query_1 TRUE 0.0025200 62 2057 19 0.0092368 0.3064516 GO:1902373 GO:BP negative regulation of mRNA catabolic process 16307 23394 GO:00064…. query_1 TRUE 0.0025244 72 2057 21 0.0102090 0.2916667 GO:1902369 GO:BP negative regulation of RNA catabolic process 16307 23390 GO:00064…. query_1 TRUE 0.0025244 72 2057 21 0.0102090 0.2916667 GO:1901992 GO:BP positive regulation of mitotic cell cycle phase transition 16307 23060 GO:00447…. query_1 TRUE 0.0026529 26 2057 11 0.0053476 0.4230769 GO:0090200 GO:BP positive regulation of release of cytochrome c from mitochondria 16307 19248 GO:00018…. query_1 TRUE 0.0026731 1572 2057 245 0.1191055 0.1558524 GO:0031328 GO:BP positive regulation of cellular biosynthetic process 16307 7554 GO:00098…. query_1 TRUE 0.0027348 5100 2057 715 0.3475936 0.1401961 GO:0080090 GO:BP regulation of primary metabolic process 16307 18924 GO:00192…. query_1 TRUE 0.0027524 48 2057 16 0.0077783 0.3333333 GO:0051972 GO:BP regulation of telomerase activity 16307 14915 GO:00513…. query_1 TRUE 0.0027613 104 2057 27 0.0131259 0.2596154 GO:1904375 GO:BP regulation of protein localization to cell periphery 16307 25052 GO:00328…. query_1 TRUE 0.0027801 312 2057 62 0.0301410 0.1987179 GO:0016050 GO:BP vesicle organization 16307 5238 GO:0006996 query_1 TRUE 0.0027811 143 2057 34 0.0165289 0.2377622 GO:1905475 GO:BP regulation of protein localization to membrane 16307 26018 GO:00328…. query_1 TRUE 0.0027837 331 2057 65 0.0315994 0.1963746 GO:0032970 GO:BP regulation of actin filament-based process 16307 8422 GO:00300…. query_1 TRUE 0.0028339 6 2057 5 0.0024307 0.8333333 GO:1904683 GO:BP regulation of metalloendopeptidase activity 16307 25320 GO:00525…. query_1 TRUE 0.0028339 6 2057 5 0.0024307 0.8333333 GO:1902255 GO:BP positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 16307 23294 GO:00723…. query_1 TRUE 0.0028411 1012 2057 166 0.0807000 0.1640316 GO:0009968 GO:BP negative regulation of signal transduction 16307 3900 GO:00071…. query_1 TRUE 0.0028442 376 2057 72 0.0350024 0.1914894 GO:0007059 GO:BP chromosome segregation 16307 2733 GO:0022402 query_1 TRUE 0.0028532 83 2057 23 0.0111813 0.2771084 GO:0034620 GO:BP cellular response to unfolded protein 16307 9198 GO:00069…. query_1 TRUE 0.0028532 83 2057 23 0.0111813 0.2771084 GO:0010833 GO:BP telomere maintenance via telomere lengthening 16307 4577 GO:0000723 query_1 TRUE 0.0028780 402 2057 76 0.0369470 0.1890547 GO:0044270 GO:BP cellular nitrogen compound catabolic process 16307 11655 GO:00346…. query_1 TRUE 0.0029292 15 2057 8 0.0038892 0.5333333 GO:0010155 GO:BP regulation of proton transport 16307 4054 GO:19026…. query_1 TRUE 0.0029456 78 2057 22 0.0106952 0.2820513 GO:0050000 GO:BP chromosome localization 16307 14006 GO:0051640 query_1 TRUE 0.0030233 1126 2057 182 0.0884784 0.1616341 GO:0019220 GO:BP regulation of phosphate metabolic process 16307 5933 GO:00067…. query_1 TRUE 0.0030600 63 2057 19 0.0092368 0.3015873 GO:1902882 GO:BP regulation of response to oxidative stress 16307 23764 GO:00069…. query_1 TRUE 0.0030752 1598 2057 248 0.1205639 0.1551940 GO:0009891 GO:BP positive regulation of biosynthetic process 16307 3845 GO:00090…. query_1 TRUE 0.0030760 167 2057 38 0.0184735 0.2275449 GO:0061013 GO:BP regulation of mRNA catabolic process 16307 16103 GO:00064…. query_1 TRUE 0.0031450 1127 2057 182 0.0884784 0.1614907 GO:0051174 GO:BP regulation of phosphorus metabolic process 16307 14402 GO:00067…. query_1 TRUE 0.0031579 35 2057 13 0.0063199 0.3714286 GO:0019068 GO:BP virion assembly 16307 5889 GO:00160…. query_1 TRUE 0.0031579 35 2057 13 0.0063199 0.3714286 GO:1903202 GO:BP negative regulation of oxidative stress-induced cell death 16307 24028 GO:00364…. query_1 TRUE 0.0031579 35 2057 13 0.0063199 0.3714286 GO:0097242 GO:BP amyloid-beta clearance 16307 19729 GO:0032501 query_1 TRUE 0.0031592 116 2057 29 0.0140982 0.2500000 GO:0008064 GO:BP regulation of actin polymerization or depolymerization 16307 3201 GO:00081…. query_1 TRUE 0.0032262 365 2057 70 0.0340301 0.1917808 GO:0034655 GO:BP nucleobase-containing compound catabolic process 16307 9219 GO:00061…. query_1 TRUE 0.0032518 133 2057 32 0.0155566 0.2406015 GO:1902904 GO:BP negative regulation of supramolecular fiber organization 16307 23783 GO:00511…. query_1 TRUE 0.0033698 100 2057 26 0.0126398 0.2600000 GO:0030833 GO:BP regulation of actin filament polymerization 16307 7320 GO:00080…. query_1 TRUE 0.0033953 385 2057 73 0.0354886 0.1896104 GO:0044772 GO:BP mitotic cell cycle phase transition 16307 11907 GO:00447…. query_1 TRUE 0.0035340 12 2057 7 0.0034030 0.5833333 GO:0001731 GO:BP formation of translation preinitiation complex 16307 431 GO:00021…. query_1 TRUE 0.0035340 19 2057 9 0.0043753 0.4736842 GO:0051444 GO:BP negative regulation of ubiquitin-protein transferase activity 16307 14569 GO:00313…. query_1 TRUE 0.0035340 19 2057 9 0.0043753 0.4736842 GO:0045947 GO:BP negative regulation of translational initiation 16307 12515 GO:00064…. query_1 TRUE 0.0035340 12 2057 7 0.0034030 0.5833333 GO:1900152 GO:BP negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 16307 21464 GO:00002…. query_1 TRUE 0.0035340 12 2057 7 0.0034030 0.5833333 GO:0035437 GO:BP maintenance of protein localization in endoplasmic reticulum 16307 9569 GO:00709…. query_1 TRUE 0.0036008 74 2057 21 0.0102090 0.2837838 GO:0051303 GO:BP establishment of chromosome localization 16307 14486 GO:00500…. query_1 TRUE 0.0037069 23 2057 10 0.0048614 0.4347826 GO:0045048 GO:BP protein insertion into ER membrane 16307 12010 GO:00070…. query_1 TRUE 0.0037069 9 2057 6 0.0029169 0.6666667 GO:0009162 GO:BP deoxyribonucleoside monophosphate metabolic process 16307 3420 GO:0009123 query_1 TRUE 0.0037069 9 2057 6 0.0029169 0.6666667 GO:0043248 GO:BP proteasome assembly 16307 11229 GO:0065003 query_1 TRUE 0.0037069 9 2057 6 0.0029169 0.6666667 GO:0043653 GO:BP mitochondrial fragmentation involved in apoptotic process 16307 11495 GO:0008637 query_1 TRUE 0.0037069 9 2057 6 0.0029169 0.6666667 GO:0006167 GO:BP AMP biosynthetic process 16307 2054 GO:00091…. query_1 TRUE 0.0037069 23 2057 10 0.0048614 0.4347826 GO:0140112 GO:BP extracellular vesicle biogenesis 16307 20891 GO:0044085 query_1 TRUE 0.0037069 23 2057 10 0.0048614 0.4347826 GO:0051131 GO:BP chaperone-mediated protein complex assembly 16307 14360 GO:0065003 query_1 TRUE 0.0037069 9 2057 6 0.0029169 0.6666667 GO:0009113 GO:BP purine nucleobase biosynthetic process 16307 3374 GO:00061…. query_1 TRUE 0.0037069 23 2057 10 0.0048614 0.4347826 GO:1902253 GO:BP regulation of intrinsic apoptotic signaling pathway by p53 class mediator 16307 23292 GO:00723…. query_1 TRUE 0.0037069 9 2057 6 0.0029169 0.6666667 GO:0045837 GO:BP negative regulation of membrane potential 16307 12429 GO:0042391 query_1 TRUE 0.0037069 27 2057 11 0.0053476 0.4074074 GO:0042307 GO:BP positive regulation of protein import into nucleus 16307 10708 GO:00066…. query_1 TRUE 0.0037906 123 2057 30 0.0145843 0.2439024 GO:0032434 GO:BP regulation of proteasomal ubiquitin-dependent protein catabolic process 16307 8024 GO:00431…. query_1 TRUE 0.0038585 101 2057 26 0.0126398 0.2574257 GO:0031398 GO:BP positive regulation of protein ubiquitination 16307 7590 GO:00165…. query_1 TRUE 0.0038653 112 2057 28 0.0136121 0.2500000 GO:0006612 GO:BP protein targeting to membrane 16307 2394 GO:00066…. query_1 TRUE 0.0038771 4 2057 4 0.0019446 1.0000000 GO:0009157 GO:BP deoxyribonucleoside monophosphate biosynthetic process 16307 3416 GO:00091…. query_1 TRUE 0.0038771 4 2057 4 0.0019446 1.0000000 GO:1905448 GO:BP positive regulation of mitochondrial ATP synthesis coupled electron transport 16307 25994 GO:00313…. query_1 TRUE 0.0038914 146 2057 34 0.0165289 0.2328767 GO:0016241 GO:BP regulation of macroautophagy 16307 5340 GO:00105…. query_1 TRUE 0.0040054 317 2057 62 0.0301410 0.1955836 GO:0006790 GO:BP sulfur compound metabolic process 16307 2545 GO:0044237 query_1 TRUE 0.0041182 414 2057 77 0.0374332 0.1859903 GO:0019439 GO:BP aromatic compound catabolic process 16307 6133 GO:00067…. query_1 TRUE 0.0041182 267 2057 54 0.0262518 0.2022472 GO:0051098 GO:BP regulation of binding 16307 14336 GO:0065009 query_1 TRUE 0.0042026 261 2057 53 0.0257657 0.2030651 GO:0001933 GO:BP negative regulation of protein phosphorylation 16307 569 GO:00019…. query_1 TRUE 0.0042686 212 2057 45 0.0218765 0.2122642 GO:0032984 GO:BP protein-containing complex disassembly 16307 8433 GO:00224…. query_1 TRUE 0.0042967 280 2057 56 0.0272241 0.2000000 GO:0051235 GO:BP maintenance of location 16307 14437 GO:0051179 query_1 TRUE 0.0042990 188 2057 41 0.0199319 0.2180851 GO:0033673 GO:BP negative regulation of kinase activity 16307 8830 GO:00423…. query_1 TRUE 0.0043581 70 2057 20 0.0097229 0.2857143 GO:0072665 GO:BP protein localization to vacuole 16307 18591 GO:0033365 query_1 TRUE 0.0045131 435 2057 80 0.0388916 0.1839080 GO:1901361 GO:BP organic cyclic compound catabolic process 16307 22498 GO:19013…. query_1 TRUE 0.0045739 1066 2057 172 0.0836169 0.1613508 GO:0023057 GO:BP negative regulation of signaling 16307 7039 GO:00230…. query_1 TRUE 0.0045788 262 2057 53 0.0257657 0.2022901 GO:0045787 GO:BP positive regulation of cell cycle 16307 12393 GO:00070…. query_1 TRUE 0.0045946 86 2057 23 0.0111813 0.2674419 GO:0007040 GO:BP lysosome organization 16307 2719 GO:0080171 query_1 TRUE 0.0045946 86 2057 23 0.0111813 0.2674419 GO:0080171 GO:BP lytic vacuole organization 16307 18972 GO:0007033 query_1 TRUE 0.0046089 1258 2057 199 0.0967428 0.1581876 GO:0009967 GO:BP positive regulation of signal transduction 16307 3899 GO:00071…. query_1 TRUE 0.0046247 32 2057 12 0.0058337 0.3750000 GO:1905898 GO:BP positive regulation of response to endoplasmic reticulum stress 16307 26371 GO:00349…. query_1 TRUE 0.0046393 281 2057 56 0.0272241 0.1992883 GO:1901990 GO:BP regulation of mitotic cell cycle phase transition 16307 23058 GO:00073…. query_1 TRUE 0.0046601 119 2057 29 0.0140982 0.2436975 GO:0030832 GO:BP regulation of actin filament length 16307 7319 GO:00325…. query_1 TRUE 0.0046668 171 2057 38 0.0184735 0.2222222 GO:0006469 GO:BP negative regulation of protein kinase activity 16307 2272 GO:00019…. query_1 TRUE 0.0047097 16 2057 8 0.0038892 0.5000000 GO:0006595 GO:BP polyamine metabolic process 16307 2379 GO:0006576 query_1 TRUE 0.0047232 1060 2057 171 0.0831308 0.1613208 GO:0010648 GO:BP negative regulation of cell communication 16307 4412 GO:00071…. query_1 TRUE 0.0050147 257 2057 52 0.0252795 0.2023346 GO:0032535 GO:BP regulation of cellular component size 16307 8094 GO:00160…. query_1 TRUE 0.0050147 28 2057 11 0.0053476 0.3928571 GO:1903513 GO:BP endoplasmic reticulum to cytosol transport 16307 24293 GO:0046907 query_1 TRUE 0.0050147 28 2057 11 0.0053476 0.3928571 GO:0030970 GO:BP retrograde protein transport, ER to cytosol 16307 7388 GO:00325…. query_1 TRUE 0.0050147 154 2057 35 0.0170151 0.2272727 GO:0001649 GO:BP osteoblast differentiation 16307 388 GO:00015…. query_1 TRUE 0.0050147 28 2057 11 0.0053476 0.3928571 GO:0019076 GO:BP viral release from host cell 16307 5897 GO:00160…. query_1 TRUE 0.0050147 28 2057 11 0.0053476 0.3928571 GO:0000470 GO:BP maturation of LSU-rRNA 16307 172 GO:00063…. query_1 TRUE 0.0050147 28 2057 11 0.0053476 0.3928571 GO:0035891 GO:BP exit from host cell 16307 9874 GO:0044000 query_1 TRUE 0.0050147 154 2057 35 0.0170151 0.2272727 GO:0015931 GO:BP nucleobase-containing compound transport 16307 5172 GO:00717…. query_1 TRUE 0.0051802 398 2057 74 0.0359747 0.1859296 GO:0046700 GO:BP heterocycle catabolic process 16307 13113 GO:00442…. query_1 TRUE 0.0052104 137 2057 32 0.0155566 0.2335766 GO:0043409 GO:BP negative regulation of MAPK cascade 16307 11324 GO:00001…. query_1 TRUE 0.0052104 20 2057 9 0.0043753 0.4500000 GO:2000434 GO:BP regulation of protein neddylation 16307 27179 GO:00451…. query_1 TRUE 0.0052104 20 2057 9 0.0043753 0.4500000 GO:0036003 GO:BP positive regulation of transcription from RNA polymerase II promoter in response to stress 16307 9949 GO:00436…. query_1 TRUE 0.0052104 184 2057 40 0.0194458 0.2173913 GO:1901214 GO:BP regulation of neuron death 16307 22377 GO:00109…. query_1 TRUE 0.0052104 20 2057 9 0.0043753 0.4500000 GO:1990182 GO:BP exosomal secretion 16307 26490 GO:00068…. query_1 TRUE 0.0052443 24 2057 10 0.0048614 0.4166667 GO:1903902 GO:BP positive regulation of viral life cycle 16307 24632 GO:00190…. query_1 TRUE 0.0052443 24 2057 10 0.0048614 0.4166667 GO:0031145 GO:BP anaphase-promoting complex-dependent catabolic process 16307 7486 GO:0043161 query_1 TRUE 0.0053239 61 2057 18 0.0087506 0.2950820 GO:0035195 GO:BP miRNA-mediated gene silencing 16307 9413 GO:0035194 query_1 TRUE 0.0053348 1291 2057 203 0.0986874 0.1572424 GO:0048585 GO:BP negative regulation of response to stimulus 16307 13679 GO:00485…. query_1 TRUE 0.0053798 1000 2057 162 0.0787555 0.1620000 GO:1901700 GO:BP response to oxygen-containing compound 16307 22780 GO:0042221 query_1 TRUE 0.0056896 132 2057 31 0.0150705 0.2348485 GO:0051017 GO:BP actin filament bundle assembly 16307 14282 GO:00226…. query_1 TRUE 0.0056896 132 2057 31 0.0150705 0.2348485 GO:0048872 GO:BP homeostasis of number of cells 16307 13938 GO:0048871 query_1 TRUE 0.0058300 93 2057 24 0.0116675 0.2580645 GO:1901989 GO:BP positive regulation of cell cycle phase transition 16307 23057 GO:00447…. query_1 TRUE 0.0058438 104 2057 26 0.0126398 0.2500000 GO:0016125 GO:BP sterol metabolic process 16307 5300 GO:00082…. query_1 TRUE 0.0059019 42 2057 14 0.0068060 0.3333333 GO:0034205 GO:BP amyloid-beta formation 16307 8990 GO:00429…. query_1 TRUE 0.0060169 453 2057 82 0.0398639 0.1810155 GO:0051493 GO:BP regulation of cytoskeleton organization 16307 14611 GO:00070…. query_1 TRUE 0.0061117 807 2057 134 0.0651434 0.1660471 GO:1901701 GO:BP cellular response to oxygen-containing compound 16307 22781 GO:00708…. query_1 TRUE 0.0061117 33 2057 12 0.0058337 0.3636364 GO:0072599 GO:BP establishment of protein localization to endoplasmic reticulum 16307 18569 GO:00709…. query_1 TRUE 0.0061117 150 2057 34 0.0165289 0.2266667 GO:0044272 GO:BP sulfur compound biosynthetic process 16307 11657 GO:00067…. query_1 TRUE 0.0062622 1497 2057 231 0.1122995 0.1543086 GO:0010557 GO:BP positive regulation of macromolecule biosynthetic process 16307 4327 GO:00090…. query_1 TRUE 0.0062866 99 2057 25 0.0121536 0.2525253 GO:0033045 GO:BP regulation of sister chromatid segregation 16307 8470 GO:00008…. query_1 TRUE 0.0064040 235 2057 48 0.0233350 0.2042553 GO:0016197 GO:BP endosomal transport 16307 5326 GO:00161…. query_1 TRUE 0.0064463 62 2057 18 0.0087506 0.2903226 GO:0008652 GO:BP amino acid biosynthetic process 16307 3315 GO:00065…. query_1 TRUE 0.0064463 62 2057 18 0.0087506 0.2903226 GO:0030968 GO:BP endoplasmic reticulum unfolded protein response 16307 7387 GO:00071…. query_1 TRUE 0.0064463 62 2057 18 0.0087506 0.2903226 GO:0043489 GO:BP RNA stabilization 16307 11385 GO:00434…. query_1 TRUE 0.0064957 57 2057 17 0.0082645 0.2982456 GO:1901607 GO:BP alpha-amino acid biosynthetic process 16307 22711 GO:00086…. query_1 TRUE 0.0065682 1383 2057 215 0.1045211 0.1554591 GO:0023056 GO:BP positive regulation of signaling 16307 7038 GO:00230…. query_1 TRUE 0.0067296 435 2057 79 0.0384054 0.1816092 GO:0030855 GO:BP epithelial cell differentiation 16307 7340 GO:00301…. query_1 TRUE 0.0067350 928 2057 151 0.0734079 0.1627155 GO:0051726 GO:BP regulation of cell cycle 16307 14784 GO:00070…. query_1 TRUE 0.0068043 29 2057 11 0.0053476 0.3793103 GO:0045047 GO:BP protein targeting to ER 16307 12009 GO:00066…. query_1 TRUE 0.0068157 151 2057 34 0.0165289 0.2251656 GO:0051168 GO:BP nuclear export 16307 14396 GO:0006913 query_1 TRUE 0.0068848 38 2057 13 0.0063199 0.3421053 GO:1902895 GO:BP positive regulation of miRNA transcription 16307 23774 GO:00458…. query_1 TRUE 0.0068848 38 2057 13 0.0063199 0.3421053 GO:0140467 GO:BP integrated stress response signaling 16307 21017 GO:0033554 query_1 TRUE 0.0069435 261 2057 52 0.0252795 0.1992337 GO:0010631 GO:BP epithelial cell migration 16307 4395 GO:00016…. query_1 TRUE 0.0071987 89 2057 23 0.0111813 0.2584270 GO:0044409 GO:BP entry into host 16307 11721 GO:0044000 query_1 TRUE 0.0072277 7 2057 5 0.0024307 0.7142857 GO:0044208 GO:BP ‘de novo’ AMP biosynthetic process 16307 11634 GO:0006167 query_1 TRUE 0.0072277 7 2057 5 0.0024307 0.7142857 GO:0006177 GO:BP GMP biosynthetic process 16307 2064 GO:00091…. query_1 TRUE 0.0072277 73 2057 20 0.0097229 0.2739726 GO:0010586 GO:BP miRNA metabolic process 16307 4352 GO:0034660 query_1 TRUE 0.0072277 17 2057 8 0.0038892 0.4705882 GO:0018195 GO:BP peptidyl-arginine modification 16307 5592 GO:0018193 query_1 TRUE 0.0072277 443 2057 80 0.0388916 0.1805869 GO:0030335 GO:BP positive regulation of cell migration 16307 7180 GO:00164…. query_1 TRUE 0.0072277 17 2057 8 0.0038892 0.4705882 GO:0090201 GO:BP negative regulation of release of cytochrome c from mitochondria 16307 19249 GO:00018…. query_1 TRUE 0.0072277 7 2057 5 0.0024307 0.7142857 GO:1903608 GO:BP protein localization to cytoplasmic stress granule 16307 24385 GO:0033365 query_1 TRUE 0.0072277 10 2057 6 0.0029169 0.6000000 GO:0071712 GO:BP ER-associated misfolded protein catabolic process 16307 17961 GO:00065…. query_1 TRUE 0.0072277 17 2057 8 0.0038892 0.4705882 GO:0044794 GO:BP positive regulation by host of viral process 16307 11922 GO:00160…. query_1 TRUE 0.0072277 10 2057 6 0.0029169 0.6000000 GO:1903069 GO:BP regulation of ER-associated ubiquitin-dependent protein catabolic process 16307 23937 GO:00304…. query_1 TRUE 0.0072277 7 2057 5 0.0024307 0.7142857 GO:1905049 GO:BP negative regulation of metallopeptidase activity 16307 25647 GO:00104…. query_1 TRUE 0.0072277 7 2057 5 0.0024307 0.7142857 GO:0033182 GO:BP regulation of histone ubiquitination 16307 8540 GO:00165…. query_1 TRUE 0.0072616 25 2057 10 0.0048614 0.4000000 GO:0006622 GO:BP protein targeting to lysosome 16307 2403 GO:00066…. query_1 TRUE 0.0073354 43 2057 14 0.0068060 0.3255814 GO:0008608 GO:BP attachment of spindle microtubules to kinetochore 16307 3296 GO:00224…. query_1 TRUE 0.0073823 206 2057 43 0.0209042 0.2087379 GO:0090068 GO:BP positive regulation of cell cycle process 16307 19133 GO:00105…. query_1 TRUE 0.0073915 417 2057 76 0.0369470 0.1822542 GO:0044089 GO:BP positive regulation of cellular component biogenesis 16307 11609 GO:00440…. query_1 TRUE 0.0074445 701 2057 118 0.0573651 0.1683310 GO:0060429 GO:BP epithelium development 16307 15559 GO:0009888 query_1 TRUE 0.0074879 21 2057 9 0.0043753 0.4285714 GO:0097734 GO:BP extracellular exosome biogenesis 16307 19933 GO:0140112 query_1 TRUE 0.0074879 21 2057 9 0.0043753 0.4285714 GO:0036010 GO:BP protein localization to endosome 16307 9953 GO:0033365 query_1 TRUE 0.0076072 48 2057 15 0.0072922 0.3125000 GO:0061462 GO:BP protein localization to lysosome 16307 16510 GO:0072665 query_1 TRUE 0.0076072 48 2057 15 0.0072922 0.3125000 GO:0050435 GO:BP amyloid-beta metabolic process 16307 14012 GO:0006518 query_1 TRUE 0.0076072 48 2057 15 0.0072922 0.3125000 GO:0006611 GO:BP protein export from nucleus 16307 2393 GO:00068…. query_1 TRUE 0.0076469 681 2057 115 0.0559067 0.1688693 GO:0032446 GO:BP protein modification by small protein conjugation 16307 8029 GO:0070647 query_1 TRUE 0.0076989 53 2057 16 0.0077783 0.3018868 GO:0042987 GO:BP amyloid precursor protein catabolic process 16307 11109 GO:0042982 query_1 TRUE 0.0076989 129 2057 30 0.0145843 0.2325581 GO:0051402 GO:BP neuron apoptotic process 16307 14554 GO:00069…. query_1 TRUE 0.0076989 53 2057 16 0.0077783 0.3018868 GO:0048255 GO:BP mRNA stabilization 16307 13429 GO:00434…. query_1 TRUE 0.0076989 129 2057 30 0.0145843 0.2325581 GO:2001056 GO:BP positive regulation of cysteine-type endopeptidase activity 16307 27746 GO:00109…. query_1 TRUE 0.0077719 34 2057 12 0.0058337 0.3529412 GO:0051973 GO:BP positive regulation of telomerase activity 16307 14916 GO:00513…. query_1 TRUE 0.0077719 34 2057 12 0.0058337 0.3529412 GO:0043516 GO:BP regulation of DNA damage response, signal transduction by p53 class mediator 16307 11398 GO:00303…. query_1 TRUE 0.0078859 135 2057 31 0.0150705 0.2296296 GO:0061572 GO:BP actin filament bundle organization 16307 16587 GO:0007015 query_1 TRUE 0.0079551 263 2057 52 0.0252795 0.1977186 GO:0090132 GO:BP epithelium migration 16307 19189 GO:0090130 query_1 TRUE 0.0081690 257 2057 51 0.0247934 0.1984436 GO:0051054 GO:BP positive regulation of DNA metabolic process 16307 14307 GO:00062…. query_1 TRUE 0.0086622 39 2057 13 0.0063199 0.3333333 GO:0090114 GO:BP COPII-coated vesicle budding 16307 19173 GO:00068…. query_1 TRUE 0.0087297 130 2057 30 0.0145843 0.2307692 GO:0051099 GO:BP positive regulation of binding 16307 14337 GO:00440…. query_1 TRUE 0.0087629 69 2057 19 0.0092368 0.2753623 GO:0042542 GO:BP response to hydrogen peroxide 16307 10864 GO:00003…. query_1 TRUE 0.0089401 30 2057 11 0.0053476 0.3666667 GO:0045070 GO:BP positive regulation of viral genome replication 16307 12032 GO:00190…. query_1 TRUE 0.0089611 113 2057 27 0.0131259 0.2389381 GO:0046165 GO:BP alcohol biosynthetic process 16307 12712 GO:00060…. query_1 TRUE 0.0090990 64 2057 18 0.0087506 0.2812500 GO:1905818 GO:BP regulation of chromosome separation 16307 26303 GO:00513…. query_1 TRUE 0.0091667 44 2057 14 0.0068060 0.3181818 GO:2000630 GO:BP positive regulation of miRNA metabolic process 16307 27348 GO:00105…. query_1 TRUE 0.0095180 1380 2057 213 0.1035489 0.1543478 GO:0010647 GO:BP positive regulation of cell communication 16307 4411 GO:00071…. query_1 TRUE 0.0095180 297 2057 57 0.0277103 0.1919192 GO:0042326 GO:BP negative regulation of phosphorylation 16307 10722 GO:00163…. query_1 TRUE 0.0095979 125 2057 29 0.0140982 0.2320000 GO:0006633 GO:BP fatty acid biosynthetic process 16307 2411 GO:00066…. query_1 TRUE 0.0098343 14 2057 7 0.0034030 0.5000000 GO:1904294 GO:BP positive regulation of ERAD pathway 16307 24972 GO:00365…. query_1 TRUE 0.0098343 14 2057 7 0.0034030 0.5000000 GO:0075294 GO:BP positive regulation by symbiont of entry into host 16307 18828 GO:00444…. query_1 TRUE 0.0098343 14 2057 7 0.0034030 0.5000000 GO:0046112 GO:BP nucleobase biosynthetic process 16307 12665 GO:00091…. query_1 TRUE 0.0098343 14 2057 7 0.0034030 0.5000000 GO:0006144 GO:BP purine nucleobase metabolic process 16307 2040 GO:00091…. query_1 TRUE 0.0098343 14 2057 7 0.0034030 0.5000000 GO:0046598 GO:BP positive regulation of viral entry into host cell 16307 13035 GO:00465…. query_1 TRUE 0.0102330 298 2057 57 0.0277103 0.1912752 GO:0032956 GO:BP regulation of actin cytoskeleton organization 16307 8409 GO:00300…. query_1 TRUE 0.0102395 149 2057 33 0.0160428 0.2214765 GO:1902905 GO:BP positive regulation of supramolecular fiber organization 16307 23784 GO:00511…. query_1 TRUE 0.0107964 204 2057 42 0.0204181 0.2058824 GO:0010632 GO:BP regulation of epithelial cell migration 16307 4396 GO:00106…. query_1 TRUE 0.0108450 65 2057 18 0.0087506 0.2769231 GO:0055072 GO:BP iron ion homeostasis 16307 15151 GO:0055076 query_1 TRUE 0.0108450 18 2057 8 0.0038892 0.4444444 GO:0002483 GO:BP antigen processing and presentation of endogenous peptide antigen 16307 1031 GO:00198…. query_1 TRUE 0.0108450 65 2057 18 0.0087506 0.2769231 GO:2000117 GO:BP negative regulation of cysteine-type endopeptidase activity 16307 26876 GO:00109…. query_1 TRUE 0.0108450 470 2057 83 0.0403500 0.1765957 GO:0051052 GO:BP regulation of DNA metabolic process 16307 14305 GO:00062…. query_1 TRUE 0.0108450 65 2057 18 0.0087506 0.2769231 GO:0035194 GO:BP RNA-mediated post-transcriptional gene silencing 16307 9412 GO:00164…. query_1 TRUE 0.0109618 267 2057 52 0.0252795 0.1947566 GO:0090130 GO:BP tissue migration 16307 19187 GO:0032501 query_1 TRUE 0.0109618 40 2057 13 0.0063199 0.3250000 GO:1903573 GO:BP negative regulation of response to endoplasmic reticulum stress 16307 24351 GO:00349…. query_1 TRUE 0.0109618 884 2057 143 0.0695187 0.1617647 GO:0006259 GO:BP DNA metabolic process 16307 2134 GO:00442…. query_1 TRUE 0.0115378 115 2057 27 0.0131259 0.2347826 GO:0051983 GO:BP regulation of chromosome segregation 16307 14922 GO:00070…. query_1 TRUE 0.0115378 115 2057 27 0.0131259 0.2347826 GO:0055076 GO:BP transition metal ion homeostasis 16307 15155 GO:0055065 query_1 TRUE 0.0115631 98 2057 24 0.0116675 0.2448980 GO:0051897 GO:BP positive regulation of protein kinase B signaling 16307 14855 GO:00434…. query_1 TRUE 0.0117948 31 2057 11 0.0053476 0.3548387 GO:0009394 GO:BP 2’-deoxyribonucleotide metabolic process 16307 3555 GO:00092…. query_1 TRUE 0.0117948 31 2057 11 0.0053476 0.3548387 GO:0019692 GO:BP deoxyribose phosphate metabolic process 16307 6364 GO:00067…. query_1 TRUE 0.0117948 31 2057 11 0.0053476 0.3548387 GO:0019082 GO:BP viral protein processing 16307 5901 GO:00160…. query_1 TRUE 0.0119821 5424 2057 747 0.3631502 0.1377212 GO:1901360 GO:BP organic cyclic compound metabolic process 16307 22497 GO:0071704 query_1 TRUE 0.0120025 753 2057 124 0.0602820 0.1646746 GO:0048878 GO:BP chemical homeostasis 16307 13942 GO:0042592 query_1 TRUE 0.0121094 127 2057 29 0.0140982 0.2283465 GO:1903008 GO:BP organelle disassembly 16307 23879 GO:00069…. query_1 TRUE 0.0121643 1121 2057 176 0.0855615 0.1570027 GO:0022402 GO:BP cell cycle process 16307 6990 GO:00070…. query_1 TRUE 0.0123136 133 2057 30 0.0145843 0.2255639 GO:0010466 GO:BP negative regulation of peptidase activity 16307 4269 GO:00458…. query_1 TRUE 0.0123286 379 2057 69 0.0335440 0.1820580 GO:0031331 GO:BP positive regulation of cellular catabolic process 16307 7557 GO:00098…. query_1 TRUE 0.0124539 139 2057 31 0.0150705 0.2230216 GO:0000723 GO:BP telomere maintenance 16307 216 GO:00062…. query_1 TRUE 0.0125582 82 2057 21 0.0102090 0.2560976 GO:0046718 GO:BP viral entry into host cell 16307 13127 GO:00190…. query_1 TRUE 0.0125582 110 2057 26 0.0126398 0.2363636 GO:0043280 GO:BP positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 16307 11246 GO:00432…. query_1 TRUE 0.0125755 163 2057 35 0.0170151 0.2147239 GO:0043487 GO:BP regulation of RNA stability 16307 11383 GO:00064…. query_1 TRUE 0.0128395 1353 2057 208 0.1011181 0.1537324 GO:0071310 GO:BP cellular response to organic substance 16307 17637 GO:00100…. query_1 TRUE 0.0128497 11 2057 6 0.0029169 0.5454545 GO:0000338 GO:BP protein deneddylation 16307 103 GO:0070646 query_1 TRUE 0.0128497 11 2057 6 0.0029169 0.5454545 GO:0006596 GO:BP polyamine biosynthetic process 16307 2380 GO:00065…. query_1 TRUE 0.0129712 36 2057 12 0.0058337 0.3333333 GO:1990748 GO:BP cellular detoxification 16307 26667 GO:00099…. query_1 TRUE 0.0129985 1339 2057 206 0.1001458 0.1538462 GO:0016192 GO:BP vesicle-mediated transport 16307 5325 GO:0006810 query_1 TRUE 0.0132605 122 2057 28 0.0136121 0.2295082 GO:0010951 GO:BP negative regulation of endopeptidase activity 16307 4671 GO:00104…. query_1 TRUE 0.0133556 27 2057 10 0.0048614 0.3703704 GO:0007176 GO:BP regulation of epidermal growth factor-activated receptor activity 16307 2818 GO:00104…. query_1 TRUE 0.0134337 88 2057 22 0.0106952 0.2500000 GO:0006637 GO:BP acyl-CoA metabolic process 16307 2415 GO:00091…. query_1 TRUE 0.0134337 88 2057 22 0.0106952 0.2500000 GO:0035383 GO:BP thioester metabolic process 16307 9545 GO:00067…. query_1 TRUE 0.0135882 5 2057 4 0.0019446 0.8000000 GO:0071680 GO:BP response to indole-3-methanol 16307 17934 GO:00102…. query_1 TRUE 0.0135882 5 2057 4 0.0019446 0.8000000 GO:1905446 GO:BP regulation of mitochondrial ATP synthesis coupled electron transport 16307 25992 GO:00427…. query_1 TRUE 0.0135882 5 2057 4 0.0019446 0.8000000 GO:0071681 GO:BP cellular response to indole-3-methanol 16307 17935 GO:00714…. query_1 TRUE 0.0135882 5 2057 4 0.0019446 0.8000000 GO:0009221 GO:BP pyrimidine deoxyribonucleotide biosynthetic process 16307 3479 GO:00062…. query_1 TRUE 0.0135882 5 2057 4 0.0019446 0.8000000 GO:0048254 GO:BP snoRNA localization 16307 13428 GO:0006403 query_1 TRUE 0.0135882 5 2057 4 0.0019446 0.8000000 GO:1990144 GO:BP intrinsic apoptotic signaling pathway in response to hypoxia 16307 26473 GO:00714…. query_1 TRUE 0.0135882 5 2057 4 0.0019446 0.8000000 GO:0006121 GO:BP mitochondrial electron transport, succinate to ubiquinone 16307 2031 GO:00196…. query_1 TRUE 0.0135882 1003 2057 159 0.0772970 0.1585244 GO:0042325 GO:BP regulation of phosphorylation 16307 10721 GO:00163…. query_1 TRUE 0.0135882 5 2057 4 0.0019446 0.8000000 GO:0090666 GO:BP scaRNA localization to Cajal body 16307 19562 GO:0090670 query_1 TRUE 0.0135882 5 2057 4 0.0019446 0.8000000 GO:0042256 GO:BP cytosolic ribosome assembly 16307 10689 GO:0042255 query_1 TRUE 0.0135882 5 2057 4 0.0019446 0.8000000 GO:0035617 GO:BP stress granule disassembly 16307 9675 GO:00329…. query_1 TRUE 0.0137539 152 2057 33 0.0160428 0.2171053 GO:0043488 GO:BP regulation of mRNA stability 16307 11384 GO:00434…. query_1 TRUE 0.0137947 46 2057 14 0.0068060 0.3043478 GO:0021762 GO:BP substantia nigra development 16307 6726 GO:00309…. query_1 TRUE 0.0137947 51 2057 15 0.0072922 0.2941176 GO:0061614 GO:BP miRNA transcription 16307 16608 GO:00063…. query_1 TRUE 0.0139698 111 2057 26 0.0126398 0.2342342 GO:1901215 GO:BP negative regulation of neuron death 16307 22378 GO:00605…. query_1 TRUE 0.0143943 117 2057 27 0.0131259 0.2307692 GO:1903052 GO:BP positive regulation of proteolysis involved in protein catabolic process 16307 23921 GO:00458…. query_1 TRUE 0.0146152 23 2057 9 0.0043753 0.3913043 GO:1902914 GO:BP regulation of protein polyubiquitination 16307 23791 GO:00002…. query_1 TRUE 0.0148338 233 2057 46 0.0223627 0.1974249 GO:0051258 GO:BP protein polymerization 16307 14457 GO:0065003 query_1 TRUE 0.0148338 177 2057 37 0.0179874 0.2090395 GO:0070482 GO:BP response to oxygen levels 16307 17191 GO:0009628 query_1 TRUE 0.0148853 67 2057 18 0.0087506 0.2686567 GO:0042982 GO:BP amyloid precursor protein metabolic process 16307 11104 GO:0019538 query_1 TRUE 0.0149322 429 2057 76 0.0369470 0.1771562 GO:0048285 GO:BP organelle fission 16307 13447 GO:0006996 query_1 TRUE 0.0149527 15 2057 7 0.0034030 0.4666667 GO:1900044 GO:BP regulation of protein K63-linked ubiquitination 16307 21363 GO:00705…. query_1 TRUE 0.0149527 32 2057 11 0.0053476 0.3437500 GO:0009262 GO:BP deoxyribonucleotide metabolic process 16307 3519 GO:00091…. query_1 TRUE 0.0149527 15 2057 7 0.0034030 0.4666667 GO:0006103 GO:BP 2-oxoglutarate metabolic process 16307 2014 GO:0043648 query_1 TRUE 0.0149527 8 2057 5 0.0024307 0.6250000 GO:0010917 GO:BP negative regulation of mitochondrial membrane potential 16307 4640 GO:00458…. query_1 TRUE 0.0149527 8 2057 5 0.0024307 0.6250000 GO:1903071 GO:BP positive regulation of ER-associated ubiquitin-dependent protein catabolic process 16307 23939 GO:00304…. query_1 TRUE 0.0149527 15 2057 7 0.0034030 0.4666667 GO:0006271 GO:BP DNA strand elongation involved in DNA replication 16307 2144 GO:00062…. query_1 TRUE 0.0149527 8 2057 5 0.0024307 0.6250000 GO:0046719 GO:BP regulation by virus of viral protein levels in host cell 16307 13128 GO:00507…. query_1 TRUE 0.0149527 8 2057 5 0.0024307 0.6250000 GO:0006621 GO:BP protein retention in ER lumen 16307 2402 GO:0035437 query_1 TRUE 0.0149527 15 2057 7 0.0034030 0.4666667 GO:0006620 GO:BP post-translational protein targeting to endoplasmic reticulum membrane 16307 2401 GO:00066…. query_1 TRUE 0.0149527 15 2057 7 0.0034030 0.4666667 GO:1903543 GO:BP positive regulation of exosomal secretion 16307 24323 GO:00440…. query_1 TRUE 0.0150778 89 2057 22 0.0106952 0.2471910 GO:0009636 GO:BP response to toxic substance 16307 3647 GO:0042221 query_1 TRUE 0.0151759 78 2057 20 0.0097229 0.2564103 GO:0032456 GO:BP endocytic recycling 16307 8032 GO:00161…. query_1 TRUE 0.0152282 19 2057 8 0.0038892 0.4210526 GO:1902992 GO:BP negative regulation of amyloid precursor protein catabolic process 16307 23863 GO:00429…. query_1 TRUE 0.0152282 19 2057 8 0.0038892 0.4210526 GO:0006613 GO:BP cotranslational protein targeting to membrane 16307 2395 GO:0006612 query_1 TRUE 0.0153665 1622 2057 244 0.1186193 0.1504316 GO:0045935 GO:BP positive regulation of nucleobase-containing compound metabolic process 16307 12505 GO:00061…. query_1 TRUE 0.0153821 62 2057 17 0.0082645 0.2741935 GO:1904356 GO:BP regulation of telomere maintenance via telomere lengthening 16307 25033 GO:00108…. query_1 TRUE 0.0159815 118 2057 27 0.0131259 0.2288136 GO:0008360 GO:BP regulation of cell shape 16307 3269 GO:0022604 query_1 TRUE 0.0159885 37 2057 12 0.0058337 0.3243243 GO:0042306 GO:BP regulation of protein import into nucleus 16307 10707 GO:00066…. query_1 TRUE 0.0159885 57 2057 16 0.0077783 0.2807018 GO:0044091 GO:BP membrane biogenesis 16307 11611 GO:0044085 query_1 TRUE 0.0159885 37 2057 12 0.0058337 0.3243243 GO:0022616 GO:BP DNA strand elongation 16307 7020 GO:0006259 query_1 TRUE 0.0159885 57 2057 16 0.0077783 0.2807018 GO:0006998 GO:BP nuclear envelope organization 16307 2688 GO:00069…. query_1 TRUE 0.0161675 73 2057 19 0.0092368 0.2602740 GO:0097581 GO:BP lamellipodium organization 16307 19887 GO:0120036 query_1 TRUE 0.0164642 52 2057 15 0.0072922 0.2884615 GO:0072666 GO:BP establishment of protein localization to vacuole 16307 18592 GO:00725…. query_1 TRUE 0.0165442 42 2057 13 0.0063199 0.3095238 GO:0044788 GO:BP modulation by host of viral process 16307 11919 GO:0051851 query_1 TRUE 0.0165967 47 2057 14 0.0068060 0.2978723 GO:1902743 GO:BP regulation of lamellipodium organization 16307 23641 GO:00975…. query_1 TRUE 0.0165967 47 2057 14 0.0068060 0.2978723 GO:0033048 GO:BP negative regulation of mitotic sister chromatid segregation 16307 8473 GO:00000…. query_1 TRUE 0.0165967 47 2057 14 0.0068060 0.2978723 GO:0033046 GO:BP negative regulation of sister chromatid segregation 16307 8471 GO:00008…. query_1 TRUE 0.0165967 47 2057 14 0.0068060 0.2978723 GO:2000816 GO:BP negative regulation of mitotic sister chromatid separation 16307 27515 GO:00109…. query_1 TRUE 0.0166782 643 2057 107 0.0520175 0.1664075 GO:0030036 GO:BP actin cytoskeleton organization 16307 7057 GO:00070…. query_1 TRUE 0.0170517 776 2057 126 0.0612543 0.1623711 GO:0006974 GO:BP cellular response to DNA damage stimulus 16307 2675 GO:0033554 query_1 TRUE 0.0171235 68 2057 18 0.0087506 0.2647059 GO:0090307 GO:BP mitotic spindle assembly 16307 19345 GO:00000…. query_1 TRUE 0.0171235 28 2057 10 0.0048614 0.3571429 GO:0090140 GO:BP regulation of mitochondrial fission 16307 19197 GO:00002…. query_1 TRUE 0.0171678 882 2057 141 0.0685464 0.1598639 GO:0001932 GO:BP regulation of protein phosphorylation 16307 568 GO:00064…. query_1 TRUE 0.0171678 319 2057 59 0.0286825 0.1849530 GO:0006631 GO:BP fatty acid metabolic process 16307 2410 GO:00327…. query_1 TRUE 0.0177381 326 2057 60 0.0291687 0.1840491 GO:0010035 GO:BP response to inorganic substance 16307 3941 GO:0042221 query_1 TRUE 0.0179306 167 2057 35 0.0170151 0.2095808 GO:0097191 GO:BP extrinsic apoptotic signaling pathway 16307 19704 GO:00071…. query_1 TRUE 0.0181228 63 2057 17 0.0082645 0.2698413 GO:0070936 GO:BP protein K48-linked ubiquitination 16307 17445 GO:0000209 query_1 TRUE 0.0182239 155 2057 33 0.0160428 0.2129032 GO:0032271 GO:BP regulation of protein polymerization 16307 7913 GO:00432…. query_1 TRUE 0.0182239 333 2057 61 0.0296548 0.1831832 GO:0001667 GO:BP ameboidal-type cell migration 16307 399 GO:0016477 query_1 TRUE 0.0183777 217 2057 43 0.0209042 0.1981567 GO:0006898 GO:BP receptor-mediated endocytosis 16307 2624 GO:0006897 query_1 TRUE 0.0189996 33 2057 11 0.0053476 0.3333333 GO:0035633 GO:BP maintenance of blood-brain barrier 16307 9685 GO:0001894 query_1 TRUE 0.0190055 58 2057 16 0.0077783 0.2758621 GO:0010965 GO:BP regulation of mitotic sister chromatid separation 16307 4683 GO:00513…. query_1 TRUE 0.0194789 24 2057 9 0.0043753 0.3750000 GO:0055094 GO:BP response to lipoprotein particle 16307 15169 GO:00097…. query_1 TRUE 0.0194789 24 2057 9 0.0043753 0.3750000 GO:0070861 GO:BP regulation of protein exit from endoplasmic reticulum 16307 17402 GO:00325…. query_1 TRUE 0.0194789 24 2057 9 0.0043753 0.3750000 GO:0019883 GO:BP antigen processing and presentation of endogenous antigen 16307 6433 GO:0019882 query_1 TRUE 0.0194857 495 2057 85 0.0413223 0.1717172 GO:0032787 GO:BP monocarboxylic acid metabolic process 16307 8290 GO:0019752 query_1 TRUE 0.0197006 53 2057 15 0.0072922 0.2830189 GO:0032210 GO:BP regulation of telomere maintenance via telomerase 16307 7863 GO:00070…. query_1 TRUE 0.0199349 120 2057 27 0.0131259 0.2250000 GO:0051170 GO:BP import into nucleus 16307 14398 GO:0006913 query_1 TRUE 0.0199388 38 2057 12 0.0058337 0.3157895 GO:0009066 GO:BP aspartate family amino acid metabolic process 16307 3334 GO:1901605 query_1 TRUE 0.0201236 80 2057 20 0.0097229 0.2500000 GO:0008630 GO:BP intrinsic apoptotic signaling pathway in response to DNA damage 16307 3309 GO:00069…. query_1 TRUE 0.0201418 48 2057 14 0.0068060 0.2916667 GO:0048145 GO:BP regulation of fibroblast proliferation 16307 13364 GO:00421…. query_1 TRUE 0.0205679 12 2057 6 0.0029169 0.5000000 GO:0034969 GO:BP histone arginine methylation 16307 9263 GO:00165…. query_1 TRUE 0.0205679 12 2057 6 0.0029169 0.5000000 GO:0072350 GO:BP tricarboxylic acid metabolic process 16307 18470 GO:0019752 query_1 TRUE 0.0205679 12 2057 6 0.0029169 0.5000000 GO:1990440 GO:BP positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 16307 26561 GO:00349…. query_1 TRUE 0.0205679 12 2057 6 0.0029169 0.5000000 GO:0070863 GO:BP positive regulation of protein exit from endoplasmic reticulum 16307 17404 GO:00325…. query_1 TRUE 0.0213242 86 2057 21 0.0102090 0.2441860 GO:0030071 GO:BP regulation of mitotic metaphase/anaphase transition 16307 7069 GO:00070…. query_1 TRUE 0.0213366 20 2057 8 0.0038892 0.4000000 GO:1904292 GO:BP regulation of ERAD pathway 16307 24970 GO:00365…. query_1 TRUE 0.0213366 20 2057 8 0.0038892 0.4000000 GO:0051220 GO:BP cytoplasmic sequestering of protein 16307 14425 GO:0045185 query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0062028 GO:BP regulation of stress granule assembly 16307 16826 GO:00340…. query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0031536 GO:BP positive regulation of exit from mitosis 16307 7640 GO:00070…. query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0046073 GO:BP dTMP metabolic process 16307 12626 GO:00091…. query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0002248 GO:BP connective tissue replacement involved in inflammatory response wound healing 16307 805 GO:00022…. query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0002484 GO:BP antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway 16307 1032 GO:0019885 query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0097010 GO:BP eukaryotic translation initiation factor 4F complex assembly 16307 19609 GO:0065003 query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0006231 GO:BP dTMP biosynthetic process 16307 2111 GO:00091…. query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0031120 GO:BP snRNA pseudouridine synthesis 16307 7466 GO:00015…. query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:1902044 GO:BP regulation of Fas signaling pathway 16307 23106 GO:00099…. query_1 TRUE 0.0215120 463 2057 80 0.0388916 0.1727862 GO:2000147 GO:BP positive regulation of cell motility 16307 26905 GO:00400…. query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:1990428 GO:BP miRNA transport 16307 26556 GO:0050658 query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:1905671 GO:BP regulation of lysosome organization 16307 26183 GO:00070…. query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0009177 GO:BP pyrimidine deoxyribonucleoside monophosphate biosynthetic process 16307 3435 GO:00091…. query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0002486 GO:BP antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent 16307 1034 GO:0002484 query_1 TRUE 0.0215120 3 2057 3 0.0014584 1.0000000 GO:0061740 GO:BP protein targeting to lysosome involved in chaperone-mediated autophagy 16307 16671 GO:00066…. query_1 TRUE 0.0216218 290 2057 54 0.0262518 0.1862069 GO:0071900 GO:BP regulation of protein serine/threonine kinase activity 16307 18062 GO:0045859 query_1 TRUE 0.0217246 16 2057 7 0.0034030 0.4375000 GO:0036499 GO:BP PERK-mediated unfolded protein response 16307 10224 GO:00069…. query_1 TRUE 0.0217246 16 2057 7 0.0034030 0.4375000 GO:0006221 GO:BP pyrimidine nucleotide biosynthetic process 16307 2102 GO:00062…. query_1 TRUE 0.0217246 396 2057 70 0.0340301 0.1767677 GO:0001819 GO:BP positive regulation of cytokine production 16307 497 GO:00018…. query_1 TRUE 0.0217246 16 2057 7 0.0034030 0.4375000 GO:1900221 GO:BP regulation of amyloid-beta clearance 16307 21526 GO:00512…. query_1 TRUE 0.0218487 323 2057 59 0.0286825 0.1826625 GO:0007159 GO:BP leukocyte cell-cell adhesion 16307 2802 GO:0098609 query_1 TRUE 0.0218487 29 2057 10 0.0048614 0.3448276 GO:2000765 GO:BP regulation of cytoplasmic translation 16307 27467 GO:00021…. query_1 TRUE 0.0220615 403 2057 71 0.0345163 0.1761787 GO:0030003 GO:BP cellular monoatomic cation homeostasis 16307 7045 GO:00068…. query_1 TRUE 0.0222268 207 2057 41 0.0199319 0.1980676 GO:0016485 GO:BP protein processing 16307 5393 GO:00065…. query_1 TRUE 0.0226230 98 2057 23 0.0111813 0.2346939 GO:0046916 GO:BP cellular transition metal ion homeostasis 16307 13237 GO:00068…. query_1 TRUE 0.0227709 70 2057 18 0.0087506 0.2571429 GO:0016441 GO:BP post-transcriptional gene silencing 16307 5381 GO:00106…. query_1 TRUE 0.0227709 70 2057 18 0.0087506 0.2571429 GO:0051304 GO:BP chromosome separation 16307 14487 GO:00070…. query_1 TRUE 0.0227709 70 2057 18 0.0087506 0.2571429 GO:1903533 GO:BP regulation of protein targeting 16307 24313 GO:00066…. query_1 TRUE 0.0229129 54 2057 15 0.0072922 0.2777778 GO:1903078 GO:BP positive regulation of protein localization to plasma membrane 16307 23946 GO:00726…. query_1 TRUE 0.0229129 54 2057 15 0.0072922 0.2777778 GO:0071709 GO:BP membrane assembly 16307 17958 GO:00226…. query_1 TRUE 0.0229129 54 2057 15 0.0072922 0.2777778 GO:0032206 GO:BP positive regulation of telomere maintenance 16307 7859 GO:00007…. query_1 TRUE 0.0231166 104 2057 24 0.0116675 0.2307692 GO:1901800 GO:BP positive regulation of proteasomal protein catabolic process 16307 22874 GO:00104…. query_1 TRUE 0.0231166 104 2057 24 0.0116675 0.2307692 GO:0007229 GO:BP integrin-mediated signaling pathway 16307 2864 GO:0007166 query_1 TRUE 0.0233177 34 2057 11 0.0053476 0.3235294 GO:0042771 GO:BP intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 16307 10988 GO:00086…. query_1 TRUE 0.0233177 214 2057 42 0.0204181 0.1962617 GO:0051346 GO:BP negative regulation of hydrolase activity 16307 14525 GO:00430…. query_1 TRUE 0.0233177 1243 2057 190 0.0923675 0.1528560 GO:0044419 GO:BP biological process involved in interspecies interaction between organisms 16307 11726 GO:0008150 query_1 TRUE 0.0233177 34 2057 11 0.0053476 0.3235294 GO:1902003 GO:BP regulation of amyloid-beta formation 16307 23070 GO:00342…. query_1 TRUE 0.0235621 49 2057 14 0.0068060 0.2857143 GO:0048144 GO:BP fibroblast proliferation 16307 13363 GO:0008283 query_1 TRUE 0.0235621 49 2057 14 0.0068060 0.2857143 GO:0051985 GO:BP negative regulation of chromosome segregation 16307 14924 GO:00070…. query_1 TRUE 0.0235621 49 2057 14 0.0068060 0.2857143 GO:1905819 GO:BP negative regulation of chromosome separation 16307 26304 GO:00513…. query_1 TRUE 0.0238801 5202 2057 713 0.3466213 0.1370627 GO:0046483 GO:BP heterocycle metabolic process 16307 12974 GO:0044237 query_1 TRUE 0.0239609 44 2057 13 0.0063199 0.2954545 GO:0071173 GO:BP spindle assembly checkpoint signaling 16307 17538 GO:0031577 query_1 TRUE 0.0239609 44 2057 13 0.0063199 0.2954545 GO:0071174 GO:BP mitotic spindle checkpoint signaling 16307 17539 GO:00070…. query_1 TRUE 0.0239609 44 2057 13 0.0063199 0.2954545 GO:0007094 GO:BP mitotic spindle assembly checkpoint signaling 16307 2756 GO:00458…. query_1 TRUE 0.0241189 134 2057 29 0.0140982 0.2164179 GO:0010634 GO:BP positive regulation of epithelial cell migration 16307 4398 GO:00106…. query_1 TRUE 0.0245727 807 2057 129 0.0627127 0.1598513 GO:0031401 GO:BP positive regulation of protein modification process 16307 7593 GO:00313…. query_1 TRUE 0.0250036 480 2057 82 0.0398639 0.1708333 GO:0044770 GO:BP cell cycle phase transition 16307 11905 GO:0022402 query_1 TRUE 0.0250944 25 2057 9 0.0043753 0.3600000 GO:0071402 GO:BP cellular response to lipoprotein particle stimulus 16307 17726 GO:0051716 query_1 TRUE 0.0251019 5236 2057 717 0.3485659 0.1369366 GO:0006725 GO:BP cellular aromatic compound metabolic process 16307 2497 GO:0044237 query_1 TRUE 0.0255968 60 2057 16 0.0077783 0.2666667 GO:1904377 GO:BP positive regulation of protein localization to cell periphery 16307 25054 GO:19038…. query_1 TRUE 0.0255968 60 2057 16 0.0077783 0.2666667 GO:0000381 GO:BP regulation of alternative mRNA splicing, via spliceosome 16307 121 GO:00003…. query_1 TRUE 0.0255968 60 2057 16 0.0077783 0.2666667 GO:0051306 GO:BP mitotic sister chromatid separation 16307 14489 GO:00000…. query_1 TRUE 0.0262645 9 2057 5 0.0024307 0.5555556 GO:1905668 GO:BP positive regulation of protein localization to endosome 16307 26180 GO:00360…. query_1 TRUE 0.0262645 111 2057 25 0.0121536 0.2252252 GO:0051225 GO:BP spindle assembly 16307 14430 GO:00070…. query_1 TRUE 0.0262645 111 2057 25 0.0121536 0.2252252 GO:2001236 GO:BP regulation of extrinsic apoptotic signaling pathway 16307 27883 GO:00971…. query_1 TRUE 0.0262645 9 2057 5 0.0024307 0.5555556 GO:1902966 GO:BP positive regulation of protein localization to early endosome 16307 23838 GO:19029…. query_1 TRUE 0.0262645 9 2057 5 0.0024307 0.5555556 GO:1904668 GO:BP positive regulation of ubiquitin protein ligase activity 16307 25307 GO:00514…. query_1 TRUE 0.0262645 9 2057 5 0.0024307 0.5555556 GO:1902965 GO:BP regulation of protein localization to early endosome 16307 23837 GO:19029…. query_1 TRUE 0.0264978 141 2057 30 0.0145843 0.2127660 GO:0051896 GO:BP regulation of protein kinase B signaling 16307 14854 GO:00434…. query_1 TRUE 0.0267142 88 2057 21 0.0102090 0.2386364 GO:1902099 GO:BP regulation of metaphase/anaphase transition of cell cycle 16307 23153 GO:00330…. query_1 TRUE 0.0269112 55 2057 15 0.0072922 0.2727273 GO:0032392 GO:BP DNA geometric change 16307 8004 GO:0071103 query_1 TRUE 0.0272223 407 2057 71 0.0345163 0.1744472 GO:0006873 GO:BP cellular monoatomic ion homeostasis 16307 2601 GO:00508…. query_1 TRUE 0.0282087 50 2057 14 0.0068060 0.2800000 GO:1902893 GO:BP regulation of miRNA transcription 16307 23772 GO:00063…. query_1 TRUE 0.0282287 503 2057 85 0.0413223 0.1689861 GO:0048871 GO:BP multicellular organismal homeostasis 16307 13937 GO:00325…. query_1 TRUE 0.0283579 21 2057 8 0.0038892 0.3809524 GO:0032986 GO:BP protein-DNA complex disassembly 16307 8435 GO:00329…. query_1 TRUE 0.0289682 45 2057 13 0.0063199 0.2888889 GO:0031577 GO:BP spindle checkpoint signaling 16307 7665 GO:0000075 query_1 TRUE 0.0289682 35 2057 11 0.0053476 0.3142857 GO:0010591 GO:BP regulation of lamellipodium assembly 16307 4357 GO:00300…. query_1 TRUE 0.0289682 45 2057 13 0.0063199 0.2888889 GO:0045841 GO:BP negative regulation of mitotic metaphase/anaphase transition 16307 12433 GO:00070…. query_1 TRUE 0.0289682 35 2057 11 0.0053476 0.3142857 GO:0032506 GO:BP cytokinetic process 16307 8076 GO:00009…. query_1 TRUE 0.0289682 35 2057 11 0.0053476 0.3142857 GO:0043618 GO:BP regulation of transcription from RNA polymerase II promoter in response to stress 16307 11465 GO:00063…. query_1 TRUE 0.0289682 45 2057 13 0.0063199 0.2888889 GO:0046596 GO:BP regulation of viral entry into host cell 16307 13033 GO:00467…. query_1 TRUE 0.0291531 40 2057 12 0.0058337 0.3000000 GO:1902991 GO:BP regulation of amyloid precursor protein catabolic process 16307 23862 GO:00429…. query_1 TRUE 0.0291531 40 2057 12 0.0058337 0.3000000 GO:0032509 GO:BP endosome transport via multivesicular body sorting pathway 16307 8079 GO:00161…. query_1 TRUE 0.0291531 40 2057 12 0.0058337 0.3000000 GO:0034314 GO:BP Arp2/3 complex-mediated actin nucleation 16307 9062 GO:0045010 query_1 TRUE 0.0291531 40 2057 12 0.0058337 0.3000000 GO:1903214 GO:BP regulation of protein targeting to mitochondrion 16307 24039 GO:00066…. query_1 TRUE 0.0291531 40 2057 12 0.0058337 0.3000000 GO:0097237 GO:BP cellular response to toxic substance 16307 19724 GO:00096…. query_1 TRUE 0.0291531 112 2057 25 0.0121536 0.2232143 GO:0031333 GO:BP negative regulation of protein-containing complex assembly 16307 7558 GO:00432…. query_1 TRUE 0.0297900 61 2057 16 0.0077783 0.2622951 GO:0070527 GO:BP platelet aggregation 16307 17216 GO:00301…. query_1 TRUE 0.0302184 89 2057 21 0.0102090 0.2359551 GO:0007091 GO:BP metaphase/anaphase transition of mitotic cell cycle 16307 2754 GO:00447…. query_1 TRUE 0.0302217 6 2057 4 0.0019446 0.6666667 GO:0043985 GO:BP histone H4-R3 methylation 16307 11566 GO:0034969 query_1 TRUE 0.0302217 6 2057 4 0.0019446 0.6666667 GO:1903551 GO:BP regulation of extracellular exosome assembly 16307 24330 GO:00719…. query_1 TRUE 0.0302217 6 2057 4 0.0019446 0.6666667 GO:1902949 GO:BP positive regulation of tau-protein kinase activity 16307 23821 GO:00458…. query_1 TRUE 0.0302217 6 2057 4 0.0019446 0.6666667 GO:1903003 GO:BP positive regulation of protein deubiquitination 16307 23874 GO:00165…. query_1 TRUE 0.0302217 6 2057 4 0.0019446 0.6666667 GO:0044387 GO:BP negative regulation of protein kinase activity by regulation of protein phosphorylation 16307 11710 GO:0006469 query_1 TRUE 0.0302217 6 2057 4 0.0019446 0.6666667 GO:0051031 GO:BP tRNA transport 16307 14288 GO:0050658 query_1 TRUE 0.0302217 6 2057 4 0.0019446 0.6666667 GO:0097577 GO:BP sequestering of iron ion 16307 19883 GO:00068…. query_1 TRUE 0.0303385 17 2057 7 0.0034030 0.4117647 GO:1903541 GO:BP regulation of exosomal secretion 16307 24321 GO:00171…. query_1 TRUE 0.0303385 17 2057 7 0.0034030 0.4117647 GO:0009067 GO:BP aspartate family amino acid biosynthetic process 16307 3335 GO:00090…. query_1 TRUE 0.0303385 17 2057 7 0.0034030 0.4117647 GO:2000641 GO:BP regulation of early endosome to late endosome transport 16307 27359 GO:00450…. query_1 TRUE 0.0309683 155 2057 32 0.0155566 0.2064516 GO:0008154 GO:BP actin polymerization or depolymerization 16307 3215 GO:0007015 query_1 TRUE 0.0311659 471 2057 80 0.0388916 0.1698514 GO:0040017 GO:BP positive regulation of locomotion 16307 10525 GO:00400…. query_1 TRUE 0.0315386 101 2057 23 0.0111813 0.2277228 GO:0031623 GO:BP receptor internalization 16307 7683 GO:0006898 query_1 TRUE 0.0317949 722 2057 116 0.0563928 0.1606648 GO:0030029 GO:BP actin filament-based process 16307 7050 GO:0009987 query_1 TRUE 0.0320000 107 2057 24 0.0116675 0.2242991 GO:0043467 GO:BP regulation of generation of precursor metabolites and energy 16307 11365 GO:00060…. query_1 TRUE 0.0321966 617 2057 101 0.0491006 0.1636953 GO:0030155 GO:BP regulation of cell adhesion 16307 7087 GO:00071…. query_1 TRUE 0.0322144 26 2057 9 0.0043753 0.3461538 GO:0008053 GO:BP mitochondrial fusion 16307 3194 GO:00070…. query_1 TRUE 0.0322144 26 2057 9 0.0043753 0.3461538 GO:1900151 GO:BP regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 16307 21463 GO:00002…. query_1 TRUE 0.0322144 26 2057 9 0.0043753 0.3461538 GO:0051085 GO:BP chaperone cofactor-dependent protein refolding 16307 14325 GO:00510…. query_1 TRUE 0.0326629 3358 2057 471 0.2289742 0.1402621 GO:0048583 GO:BP regulation of response to stimulus 16307 13677 GO:00507…. query_1 TRUE 0.0327185 84 2057 20 0.0097229 0.2380952 GO:0034109 GO:BP homotypic cell-cell adhesion 16307 8903 GO:0098609 query_1 TRUE 0.0327185 84 2057 20 0.0097229 0.2380952 GO:0009185 GO:BP ribonucleoside diphosphate metabolic process 16307 3443 GO:0009132 query_1 TRUE 0.0329425 51 2057 14 0.0068060 0.2745098 GO:0048857 GO:BP neural nucleus development 16307 13924 GO:0048856 query_1 TRUE 0.0338933 90 2057 21 0.0102090 0.2333333 GO:1905477 GO:BP positive regulation of protein localization to membrane 16307 26020 GO:00726…. query_1 TRUE 0.0344315 46 2057 13 0.0063199 0.2826087 GO:1903747 GO:BP regulation of establishment of protein localization to mitochondrion 16307 24507 GO:00702…. query_1 TRUE 0.0345557 31 2057 10 0.0048614 0.3225806 GO:0036258 GO:BP multivesicular body assembly 16307 10095 GO:00362…. query_1 TRUE 0.0345557 31 2057 10 0.0048614 0.3225806 GO:0051084 GO:BP ‘de novo’ post-translational protein folding 16307 14324 GO:0006458 query_1 TRUE 0.0345557 31 2057 10 0.0048614 0.3225806 GO:0070198 GO:BP protein localization to chromosome, telomeric region 16307 17022 GO:0034502 query_1 TRUE 0.0350365 619 2057 101 0.0491006 0.1631664 GO:0010564 GO:BP regulation of cell cycle process 16307 4334 GO:00224…. query_1 TRUE 0.0352625 41 2057 12 0.0058337 0.2926829 GO:0043620 GO:BP regulation of DNA-templated transcription in response to stress 16307 11467 GO:00063…. query_1 TRUE 0.0353502 36 2057 11 0.0053476 0.3055556 GO:0045324 GO:BP late endosome to vacuole transport 16307 12126 GO:00070…. query_1 TRUE 0.0353502 36 2057 11 0.0053476 0.3055556 GO:0006623 GO:BP protein targeting to vacuole 16307 2404 GO:00066…. query_1 TRUE 0.0353502 36 2057 11 0.0053476 0.3055556 GO:0040001 GO:BP establishment of mitotic spindle localization 16307 10510 GO:00512…. query_1 TRUE 0.0358309 188 2057 37 0.0179874 0.1968085 GO:0007033 GO:BP vacuole organization 16307 2713 GO:0006996 query_1 TRUE 0.0364062 768 2057 122 0.0593097 0.1588542 GO:0030334 GO:BP regulation of cell migration 16307 7179 GO:00164…. query_1 TRUE 0.0364062 5057 2057 691 0.3359261 0.1366423 GO:0006139 GO:BP nucleobase-containing compound metabolic process 16307 2036 GO:00067…. query_1 TRUE 0.0364723 613 2057 100 0.0486145 0.1631321 GO:0016567 GO:BP protein ubiquitination 16307 5414 GO:0032446 query_1 TRUE 0.0367041 57 2057 15 0.0072922 0.2631579 GO:0090559 GO:BP regulation of membrane permeability 16307 19518 GO:0065008 query_1 TRUE 0.0372106 22 2057 8 0.0038892 0.3636364 GO:0051043 GO:BP regulation of membrane protein ectodomain proteolysis 16307 14296 GO:00065…. query_1 TRUE 0.0372106 22 2057 8 0.0038892 0.3636364 GO:0039702 GO:BP viral budding via host ESCRT complex 16307 10498 GO:0046755 query_1 TRUE 0.0372106 22 2057 8 0.0038892 0.3636364 GO:0009112 GO:BP nucleobase metabolic process 16307 3373 GO:00550…. query_1 TRUE 0.0372106 214 2057 41 0.0199319 0.1915888 GO:1903039 GO:BP positive regulation of leukocyte cell-cell adhesion 16307 23908 GO:00071…. query_1 TRUE 0.0372106 22 2057 8 0.0038892 0.3636364 GO:0032069 GO:BP regulation of nuclease activity 16307 7787 GO:00513…. query_1 TRUE 0.0372595 266 2057 49 0.0238211 0.1842105 GO:0006066 GO:BP alcohol metabolic process 16307 1983 GO:00442…. query_1 TRUE 0.0380434 91 2057 21 0.0102090 0.2307692 GO:0044784 GO:BP metaphase/anaphase transition of cell cycle 16307 11915 GO:00330…. query_1 TRUE 0.0384871 170 2057 34 0.0165289 0.2000000 GO:0072593 GO:BP reactive oxygen species metabolic process 16307 18563 GO:0044237 query_1 TRUE 0.0384871 1209 2057 183 0.0889645 0.1513648 GO:0016477 GO:BP cell migration 16307 5389 GO:0048870 query_1 TRUE 0.0386917 713 2057 114 0.0554205 0.1598878 GO:0009628 GO:BP response to abiotic stimulus 16307 3642 GO:0050896 query_1 TRUE 0.0387290 52 2057 14 0.0068060 0.2692308 GO:0045839 GO:BP negative regulation of mitotic nuclear division 16307 12431 GO:00070…. query_1 TRUE 0.0387290 52 2057 14 0.0068060 0.2692308 GO:0043154 GO:BP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 16307 11202 GO:00430…. query_1 TRUE 0.0387290 52 2057 14 0.0068060 0.2692308 GO:1901655 GO:BP cellular response to ketone 16307 22745 GO:19016…. query_1 TRUE 0.0395950 115 2057 25 0.0121536 0.2173913 GO:0006606 GO:BP protein import into nucleus 16307 2390 GO:00068…. query_1 TRUE 0.0397034 63 2057 16 0.0077783 0.2539683 GO:0071103 GO:BP DNA conformation change 16307 17522 GO:0051276 query_1 TRUE 0.0400832 158 2057 32 0.0155566 0.2025316 GO:0001666 GO:BP response to hypoxia 16307 398 GO:00069…. query_1 TRUE 0.0400832 158 2057 32 0.0155566 0.2025316 GO:0043491 GO:BP protein kinase B signaling 16307 11387 GO:0035556 query_1 TRUE 0.0404964 80 2057 19 0.0092368 0.2375000 GO:0007029 GO:BP endoplasmic reticulum organization 16307 2709 GO:00069…. query_1 TRUE 0.0406990 47 2057 13 0.0063199 0.2765957 GO:0030837 GO:BP negative regulation of actin filament polymerization 16307 7324 GO:00300…. query_1 TRUE 0.0406990 47 2057 13 0.0063199 0.2765957 GO:1902100 GO:BP negative regulation of metaphase/anaphase transition of cell cycle 16307 23154 GO:00447…. query_1 TRUE 0.0409478 463 2057 78 0.0379193 0.1684665 GO:0055080 GO:BP monoatomic cation homeostasis 16307 15158 GO:0050801 query_1 TRUE 0.0410919 27 2057 9 0.0043753 0.3333333 GO:0051156 GO:BP glucose 6-phosphate metabolic process 16307 14384 GO:00067…. query_1 TRUE 0.0417301 18 2057 7 0.0034030 0.3888889 GO:0006098 GO:BP pentose-phosphate shunt 16307 2010 GO:00067…. query_1 TRUE 0.0417301 18 2057 7 0.0034030 0.3888889 GO:0051988 GO:BP regulation of attachment of spindle microtubules to kinetochore 16307 14927 GO:00086…. query_1 TRUE 0.0417301 18 2057 7 0.0034030 0.3888889 GO:0046033 GO:BP AMP metabolic process 16307 12586 GO:00091…. query_1 TRUE 0.0417301 18 2057 7 0.0034030 0.3888889 GO:1904996 GO:BP positive regulation of leukocyte adhesion to vascular endothelial cell 16307 25595 GO:00617…. query_1 TRUE 0.0419882 58 2057 15 0.0072922 0.2586207 GO:0098754 GO:BP detoxification 16307 20059 GO:00081…. query_1 TRUE 0.0419882 10 2057 5 0.0024307 0.5000000 GO:0090435 GO:BP protein localization to nuclear envelope 16307 19447 GO:0034504 query_1 TRUE 0.0419882 58 2057 15 0.0072922 0.2586207 GO:0030032 GO:BP lamellipodium assembly 16307 7053 GO:00975…. query_1 TRUE 0.0419882 10 2057 5 0.0024307 0.5000000 GO:0002053 GO:BP positive regulation of mesenchymal cell proliferation 16307 676 GO:00082…. query_1 TRUE 0.0419882 92 2057 21 0.0102090 0.2282609 GO:2001251 GO:BP negative regulation of chromosome organization 16307 27898 GO:00106…. query_1 TRUE 0.0419882 10 2057 5 0.0024307 0.5000000 GO:1904667 GO:BP negative regulation of ubiquitin protein ligase activity 16307 25306 GO:00514…. query_1 TRUE 0.0419882 92 2057 21 0.0102090 0.2282609 GO:0002262 GO:BP myeloid cell homeostasis 16307 819 GO:00023…. query_1 TRUE 0.0419882 58 2057 15 0.0072922 0.2586207 GO:0048002 GO:BP antigen processing and presentation of peptide antigen 16307 13274 GO:0019882 query_1 TRUE 0.0419882 42 2057 12 0.0058337 0.2857143 GO:0030042 GO:BP actin filament depolymerization 16307 7061 GO:00081…. query_1 TRUE 0.0419882 42 2057 12 0.0058337 0.2857143 GO:0071763 GO:BP nuclear membrane organization 16307 17979 GO:00069…. query_1 TRUE 0.0419882 10 2057 5 0.0024307 0.5000000 GO:0032070 GO:BP regulation of deoxyribonuclease activity 16307 7788 GO:00320…. query_1 TRUE 0.0419882 10 2057 5 0.0024307 0.5000000 GO:1905666 GO:BP regulation of protein localization to endosome 16307 26178 GO:00328…. query_1 TRUE 0.0419882 10 2057 5 0.0024307 0.5000000 GO:0090594 GO:BP inflammatory response to wounding 16307 19523 GO:00069…. query_1 TRUE 0.0419882 10 2057 5 0.0024307 0.5000000 GO:1902947 GO:BP regulation of tau-protein kinase activity 16307 23819 GO:0045859 query_1 TRUE 0.0419882 822 2057 129 0.0627127 0.1569343 GO:0070647 GO:BP protein modification by small protein conjugation or removal 16307 17286 GO:0036211 query_1 TRUE 0.0419882 512 2057 85 0.0413223 0.1660156 GO:0055082 GO:BP cellular chemical homeostasis 16307 15160 GO:00197…. query_1 TRUE 0.0419882 10 2057 5 0.0024307 0.5000000 GO:0031293 GO:BP membrane protein intracellular domain proteolysis 16307 7540 GO:0033619 query_1 TRUE 0.0419882 10 2057 5 0.0024307 0.5000000 GO:2000644 GO:BP regulation of receptor catabolic process 16307 27362 GO:00313…. query_1 TRUE 0.0420449 32 2057 10 0.0048614 0.3125000 GO:0036257 GO:BP multivesicular body organization 16307 10094 GO:0007032 query_1 TRUE 0.0420449 32 2057 10 0.0048614 0.3125000 GO:1902745 GO:BP positive regulation of lamellipodium organization 16307 23643 GO:00313…. query_1 TRUE 0.0424600 98 2057 22 0.0106952 0.2244898 GO:0009132 GO:BP nucleoside diphosphate metabolic process 16307 3391 GO:0006753 query_1 TRUE 0.0430214 110 2057 24 0.0116675 0.2181818 GO:0034502 GO:BP protein localization to chromosome 16307 9173 GO:0033365 query_1 TRUE 0.0432630 178 2057 35 0.0170151 0.1966292 GO:0051651 GO:BP maintenance of location in cell 16307 14735 GO:00099…. query_1 TRUE 0.0437414 14 2057 6 0.0029169 0.4285714 GO:0043518 GO:BP negative regulation of DNA damage response, signal transduction by p53 class mediator 16307 11400 GO:00303…. query_1 TRUE 0.0437414 14 2057 6 0.0029169 0.4285714 GO:0046653 GO:BP tetrahydrofolate metabolic process 16307 13075 GO:0006760 query_1 TRUE 0.0437414 14 2057 6 0.0029169 0.4285714 GO:0043922 GO:BP negative regulation by host of viral transcription 16307 11520 GO:00190…. query_1 TRUE 0.0437414 14 2057 6 0.0029169 0.4285714 GO:0046040 GO:BP IMP metabolic process 16307 12593 GO:00091…. query_1 TRUE 0.0437414 14 2057 6 0.0029169 0.4285714 GO:0018216 GO:BP peptidyl-arginine methylation 16307 5612 GO:00064…. query_1 TRUE 0.0446062 53 2057 14 0.0068060 0.2641509 GO:0006879 GO:BP cellular iron ion homeostasis 16307 2607 GO:00469…. query_1 TRUE 0.0448486 64 2057 16 0.0077783 0.2500000 GO:0008625 GO:BP extrinsic apoptotic signaling pathway via death domain receptors 16307 3305 GO:0097191 query_1 TRUE 0.0448486 81 2057 19 0.0092368 0.2345679 GO:0000422 GO:BP autophagy of mitochondrion 16307 137 GO:00069…. query_1 TRUE 0.0448486 81 2057 19 0.0092368 0.2345679 GO:0061726 GO:BP mitochondrion disassembly 16307 16661 GO:00070…. query_1 TRUE 0.0467508 129 2057 27 0.0131259 0.2093023 GO:0030041 GO:BP actin filament polymerization 16307 7060 GO:00081…. query_1 TRUE 0.0470127 93 2057 21 0.0102090 0.2258065 GO:2001252 GO:BP positive regulation of chromosome organization 16307 27899 GO:00106…. query_1 TRUE 0.0472083 23 2057 8 0.0038892 0.3478261 GO:0036474 GO:BP cell death in response to hydrogen peroxide 16307 10204 GO:00364…. query_1 TRUE 0.0472083 48 2057 13 0.0063199 0.2708333 GO:0045010 GO:BP actin nucleation 16307 11990 GO:0007015 query_1 TRUE 0.0472083 23 2057 8 0.0038892 0.3478261 GO:0071404 GO:BP cellular response to low-density lipoprotein particle stimulus 16307 17728 GO:00550…. query_1 TRUE 0.0472083 23 2057 8 0.0038892 0.3478261 GO:0046825 GO:BP regulation of protein export from nucleus 16307 13178 GO:00066…. query_1 TRUE 0.0472083 117 2057 25 0.0121536 0.2136752 GO:0033875 GO:BP ribonucleoside bisphosphate metabolic process 16307 8852 GO:0033865 query_1 TRUE 0.0472083 48 2057 13 0.0063199 0.2708333 GO:1902808 GO:BP positive regulation of cell cycle G1/S phase transition 16307 23702 GO:00448…. query_1 TRUE 0.0472083 70 2057 17 0.0082645 0.2428571 GO:0030901 GO:BP midbrain development 16307 7359 GO:00074…. query_1 TRUE 0.0472083 23 2057 8 0.0038892 0.3478261 GO:0060333 GO:BP type II interferon-mediated signaling pathway 16307 15472 GO:00713…. query_1 TRUE 0.0472083 23 2057 8 0.0038892 0.3478261 GO:1900370 GO:BP positive regulation of post-transcriptional gene silencing by RNA 16307 21666 GO:00351…. query_1 TRUE 0.0472083 23 2057 8 0.0038892 0.3478261 GO:0048208 GO:BP COPII vesicle coating 16307 13402 GO:00069…. query_1 TRUE 0.0472083 117 2057 25 0.0121536 0.2136752 GO:0034032 GO:BP purine nucleoside bisphosphate metabolic process 16307 8862 GO:00338…. query_1 TRUE 0.0472083 48 2057 13 0.0063199 0.2708333 GO:0030865 GO:BP cortical cytoskeleton organization 16307 7348 GO:0007010 query_1 TRUE 0.0472083 117 2057 25 0.0121536 0.2136752 GO:0033865 GO:BP nucleoside bisphosphate metabolic process 16307 8849 GO:0006753 query_1 TRUE 0.0472083 23 2057 8 0.0038892 0.3478261 GO:0048207 GO:BP vesicle targeting, rough ER to cis-Golgi 16307 13401 GO:00068…. query_1 TRUE 0.0472083 23 2057 8 0.0038892 0.3478261 GO:0060148 GO:BP positive regulation of post-transcriptional gene silencing 16307 15315 GO:00164…. query_1 TRUE 0.0479596 59 2057 15 0.0072922 0.2542373 GO:1901657 GO:BP glycosyl compound metabolic process 16307 22747 GO:1901135 query_1 TRUE 0.0479596 59 2057 15 0.0072922 0.2542373 GO:0032272 GO:BP negative regulation of protein polymerization 16307 7914 GO:00313…. query_1 TRUE 0.0479596 59 2057 15 0.0072922 0.2542373 GO:2000628 GO:BP regulation of miRNA metabolic process 16307 27346 GO:00105…. query_1 TRUE 0.0488622 76 2057 18 0.0087506 0.2368421 GO:0043524 GO:BP negative regulation of neuron apoptotic process 16307 11405 GO:00430…. query_1 TRUE 0.0491082 43 2057 12 0.0058337 0.2790698 GO:2000059 GO:BP negative regulation of ubiquitin-dependent protein catabolic process 16307 26819 GO:00065…. query_1 TRUE 0.0492776 607 2057 98 0.0476422 0.1614498 GO:0001816 GO:BP cytokine production 16307 494 GO:00104…. query_1 TRUE 0.0000000 292 1676 183 0.1091885 0.6267123 REAC:R-HSA-72766 REAC Translation 10777 2429 REAC:R-H…. query_1 TRUE 0.0000000 171 1676 130 0.0775656 0.7602339 REAC:R-HSA-9010553 REAC Regulation of expression of SLITs and ROBOs 10777 1916 REAC:R-H…. query_1 TRUE 0.0000000 112 1676 99 0.0590692 0.8839286 REAC:R-HSA-156827 REAC L13a-mediated translational silencing of Ceruloplasmin expression 10777 1231 REAC:R-H…. query_1 TRUE 0.0000000 113 1676 99 0.0590692 0.8761062 REAC:R-HSA-72706 REAC GTP hydrolysis and joining of the 60S ribosomal subunit 10777 973 REAC:R-H…. query_1 TRUE 0.0000000 120 1676 102 0.0608592 0.8500000 REAC:R-HSA-72737 REAC Cap-dependent Translation Initiation 10777 293 REAC:R-H…. query_1 TRUE 0.0000000 120 1676 102 0.0608592 0.8500000 REAC:R-HSA-72613 REAC Eukaryotic Translation Initiation 10777 828 REAC:R-H…. query_1 TRUE 0.0000000 102 1676 91 0.0542959 0.8921569 REAC:R-HSA-72689 REAC Formation of a pool of free 40S subunits 10777 906 REAC:R-H…. query_1 TRUE 0.0000000 217 1676 138 0.0823389 0.6359447 REAC:R-HSA-376176 REAC Signaling by ROBO receptors 10777 2176 REAC:R-H…. query_1 TRUE 0.0000000 113 1676 95 0.0566826 0.8407080 REAC:R-HSA-1799339 REAC SRP-dependent cotranslational protein targeting to membrane 10777 2034 REAC:R-H…. query_1 TRUE 0.0000000 94 1676 85 0.0507160 0.9042553 REAC:R-HSA-156842 REAC Eukaryotic Translation Elongation 10777 827 REAC:R-H…. query_1 TRUE 0.0000000 661 1676 267 0.1593079 0.4039334 REAC:R-HSA-8953854 REAC Metabolism of RNA 10777 1343 REAC:0000000 query_1 TRUE 0.0000000 90 1676 81 0.0483294 0.9000000 REAC:R-HSA-156902 REAC Peptide chain elongation 10777 1633 REAC:R-H…. query_1 TRUE 0.0000000 94 1676 83 0.0495227 0.8829787 REAC:R-HSA-72764 REAC Eukaryotic Translation Termination 10777 829 REAC:R-H…. query_1 TRUE 0.0000000 96 1676 84 0.0501193 0.8750000 REAC:R-HSA-975956 REAC Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 10777 1521 REAC:R-H…. query_1 TRUE 0.0000000 102 1676 86 0.0513126 0.8431373 REAC:R-HSA-9633012 REAC Response of EIF2AK4 (GCN2) to amino acid deficiency 10777 1966 REAC:R-H…. query_1 TRUE 0.0000000 778 1676 289 0.1724344 0.3714653 REAC:R-HSA-2262752 REAC Cellular responses to stress 10777 326 REAC:R-H…. query_1 TRUE 0.0000000 792 1676 292 0.1742243 0.3686869 REAC:R-HSA-8953897 REAC Cellular responses to stimuli 10777 325 REAC:0000000 query_1 TRUE 0.0000000 90 1676 79 0.0471360 0.8777778 REAC:R-HSA-192823 REAC Viral mRNA Translation 10777 2511 REAC:R-H…. query_1 TRUE 0.0000000 94 1676 80 0.0477327 0.8510638 REAC:R-HSA-2408557 REAC Selenocysteine synthesis 10777 2065 REAC:R-H…. query_1 TRUE 0.0000000 157 1676 106 0.0632458 0.6751592 REAC:R-HSA-9711097 REAC Cellular response to starvation 10777 324 REAC:R-H…. query_1 TRUE 0.0000000 116 1676 89 0.0531026 0.7672414 REAC:R-HSA-975957 REAC Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 10777 1520 REAC:R-H…. query_1 TRUE 0.0000000 116 1676 89 0.0531026 0.7672414 REAC:R-HSA-927802 REAC Nonsense-Mediated Decay (NMD) 10777 1522 REAC:R-H…. query_1 TRUE 0.0000000 1945 1676 518 0.3090692 0.2663239 REAC:R-HSA-392499 REAC Metabolism of proteins 10777 1359 REAC:0000000 query_1 TRUE 0.0000000 152 1676 99 0.0590692 0.6513158 REAC:R-HSA-168255 REAC Influenza Infection 10777 1125 REAC:R-H…. query_1 TRUE 0.0000000 133 1676 90 0.0536993 0.6766917 REAC:R-HSA-168273 REAC Influenza Viral RNA Transcription and Replication 10777 1126 REAC:R-H…. query_1 TRUE 0.0000000 117 1676 83 0.0495227 0.7094017 REAC:R-HSA-2408522 REAC Selenoamino acid metabolism 10777 2064 REAC:R-H…. query_1 TRUE 0.0000000 369 1676 162 0.0966587 0.4390244 REAC:R-HSA-71291 REAC Metabolism of amino acids and derivatives 10777 1345 REAC:R-H…. query_1 TRUE 0.0000000 1051 1676 316 0.1885442 0.3006660 REAC:R-HSA-5663205 REAC Infectious disease 10777 1123 REAC:R-H…. query_1 TRUE 0.0000000 60 1676 52 0.0310263 0.8666667 REAC:R-HSA-72662 REAC Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 10777 101 REAC:R-H…. query_1 TRUE 0.0000000 574 1676 204 0.1217184 0.3554007 REAC:R-HSA-9675108 REAC Nervous system development 10777 1498 REAC:R-H…. query_1 TRUE 0.0000000 549 1676 198 0.1181384 0.3606557 REAC:R-HSA-422475 REAC Axon guidance 10777 187 REAC:R-H…. query_1 TRUE 0.0000000 59 1676 51 0.0304296 0.8644068 REAC:R-HSA-72649 REAC Translation initiation complex formation 10777 2430 REAC:R-H…. query_1 TRUE 0.0000000 59 1676 51 0.0304296 0.8644068 REAC:R-HSA-72702 REAC Ribosomal scanning and start codon recognition 10777 1984 REAC:R-H…. query_1 TRUE 0.0000000 103 1676 70 0.0417661 0.6796117 REAC:R-HSA-611105 REAC Respiratory electron transport 10777 1963 REAC:R-H…. query_1 TRUE 0.0000000 2072 1676 508 0.3031026 0.2451737 REAC:R-HSA-1430728 REAC Metabolism 10777 1341 REAC:0000000 query_1 TRUE 0.0000000 52 1676 46 0.0274463 0.8846154 REAC:R-HSA-72695 REAC Formation of the ternary complex, and subsequently, the 43S complex 10777 920 REAC:R-H…. query_1 TRUE 0.0000000 192 1676 98 0.0584726 0.5104167 REAC:R-HSA-8868773 REAC rRNA processing in the nucleus and cytosol 10777 2593 REAC:R-H…. query_1 TRUE 0.0000000 53 1676 46 0.0274463 0.8679245 REAC:R-HSA-9604323 REAC Negative regulation of NOTCH4 signaling 10777 1491 REAC:R-H…. query_1 TRUE 0.0000000 77 1676 57 0.0340095 0.7402597 REAC:R-HSA-176814 REAC Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 10777 70 REAC:R-H…. query_1 TRUE 0.0000000 182 1676 94 0.0560859 0.5164835 REAC:R-HSA-6791226 REAC Major pathway of rRNA processing in the nucleolus and cytosol 10777 1319 REAC:R-H…. query_1 TRUE 0.0000000 52 1676 45 0.0268496 0.8653846 REAC:R-HSA-9762114 REAC GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 10777 972 REAC:R-H…. query_1 TRUE 0.0000000 76 1676 56 0.0334129 0.7368421 REAC:R-HSA-176409 REAC APC/C:Cdc20 mediated degradation of mitotic proteins 10777 24 REAC:R-H…. query_1 TRUE 0.0000000 54 1676 46 0.0274463 0.8518519 REAC:R-HSA-450408 REAC AUF1 (hnRNP D0) binds and destabilizes mRNA 10777 36 REAC:R-H…. query_1 TRUE 0.0000000 476 1676 172 0.1026253 0.3613445 REAC:R-HSA-6798695 REAC Neutrophil degranulation 10777 1511 REAC:R-H…. query_1 TRUE 0.0000000 202 1676 99 0.0590692 0.4900990 REAC:R-HSA-72312 REAC rRNA processing 10777 2591 REAC:R-H…. query_1 TRUE 0.0000000 177 1676 91 0.0542959 0.5141243 REAC:R-HSA-1428517 REAC The citric acid (TCA) cycle and respiratory electron transport 10777 2365 REAC:R-H…. query_1 TRUE 0.0000000 68 1676 52 0.0310263 0.7647059 REAC:R-HSA-174154 REAC APC/C:Cdc20 mediated degradation of Securin 10777 23 REAC:R-H…. query_1 TRUE 0.0000000 191 1676 95 0.0566826 0.4973822 REAC:R-HSA-9711123 REAC Cellular response to chemical stress 10777 321 REAC:R-H…. query_1 TRUE 0.0000000 73 1676 54 0.0322196 0.7397260 REAC:R-HSA-174184 REAC Cdc20:Phospho-APC/C mediated degradation of Cyclin A 10777 307 REAC:R-H…. query_1 TRUE 0.0000000 78 1676 56 0.0334129 0.7179487 REAC:R-HSA-9759194 REAC Nuclear events mediated by NFE2L2 10777 1531 REAC:R-H…. query_1 TRUE 0.0000000 64 1676 50 0.0298329 0.7812500 REAC:R-HSA-174084 REAC Autodegradation of Cdh1 by Cdh1:APC/C 10777 183 REAC:R-H…. query_1 TRUE 0.0000000 81 1676 57 0.0340095 0.7037037 REAC:R-HSA-176408 REAC Regulation of APC/C activators between G1/S and early anaphase 10777 1870 REAC:R-H…. query_1 TRUE 0.0000000 74 1676 54 0.0322196 0.7297297 REAC:R-HSA-174178 REAC APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 10777 25 REAC:R-H…. query_1 TRUE 0.0000000 74 1676 54 0.0322196 0.7297297 REAC:R-HSA-179419 REAC APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 10777 26 REAC:R-H…. query_1 TRUE 0.0000000 56 1676 46 0.0274463 0.8214286 REAC:R-HSA-5362768 REAC Hh mutants are degraded by ERAD 10777 1064 REAC:R-H…. query_1 TRUE 0.0000000 52 1676 44 0.0262530 0.8461538 REAC:R-HSA-75815 REAC Ubiquitin-dependent degradation of Cyclin D 10777 2482 REAC:R-H…. query_1 TRUE 0.0000000 61 1676 48 0.0286396 0.7868852 REAC:R-HSA-5678895 REAC Defective CFTR causes cystic fibrosis 10777 484 REAC:R-H…. query_1 TRUE 0.0000000 88 1676 59 0.0352029 0.6704545 REAC:R-HSA-453276 REAC Regulation of mitotic cell cycle 10777 1929 REAC:R-H…. query_1 TRUE 0.0000000 88 1676 59 0.0352029 0.6704545 REAC:R-HSA-174143 REAC APC/C-mediated degradation of cell cycle proteins 10777 21 REAC:R-H…. query_1 TRUE 0.0000000 127 1676 73 0.0435561 0.5748031 REAC:R-HSA-163200 REAC Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 10777 1964 REAC:R-H…. query_1 TRUE 0.0000000 55 1676 45 0.0268496 0.8181818 REAC:R-HSA-8854050 REAC FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 10777 846 REAC:R-H…. query_1 TRUE 0.0000000 53 1676 44 0.0262530 0.8301887 REAC:R-HSA-180585 REAC Vif-mediated degradation of APOBEC3G 10777 2508 REAC:R-H…. query_1 TRUE 0.0000000 51 1676 43 0.0256563 0.8431373 REAC:R-HSA-350562 REAC Regulation of ornithine decarboxylase (ODC) 10777 1931 REAC:R-H…. query_1 TRUE 0.0000000 79 1676 55 0.0328162 0.6962025 REAC:R-HSA-8852276 REAC The role of GTSE1 in G2/M progression after G2 checkpoint 10777 2370 REAC:R-H…. query_1 TRUE 0.0000000 58 1676 46 0.0274463 0.7931034 REAC:R-HSA-351202 REAC Metabolism of polyamines 10777 1357 REAC:R-H…. query_1 TRUE 0.0000000 52 1676 43 0.0256563 0.8269231 REAC:R-HSA-180534 REAC Vpu mediated degradation of CD4 10777 2527 REAC:R-H…. query_1 TRUE 0.0000000 52 1676 43 0.0256563 0.8269231 REAC:R-HSA-349425 REAC Autodegradation of the E3 ubiquitin ligase COP1 10777 184 REAC:R-H…. query_1 TRUE 0.0000000 50 1676 42 0.0250597 0.8400000 REAC:R-HSA-211733 REAC Regulation of activated PAK-2p34 by proteasome mediated degradation 10777 1910 REAC:R-H…. query_1 TRUE 0.0000000 59 1676 46 0.0274463 0.7796610 REAC:R-HSA-5387390 REAC Hh mutants abrogate ligand secretion 10777 1063 REAC:R-H…. query_1 TRUE 0.0000000 66 1676 49 0.0292363 0.7424242 REAC:R-HSA-1234176 REAC Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 10777 1567 REAC:R-H…. query_1 TRUE 0.0000000 55 1676 44 0.0262530 0.8000000 REAC:R-HSA-174113 REAC SCF-beta-TrCP mediated degradation of Emi1 10777 2008 REAC:R-H…. query_1 TRUE 0.0000000 60 1676 46 0.0274463 0.7666667 REAC:R-HSA-187577 REAC SCF(Skp2)-mediated degradation of p27/p21 10777 2007 REAC:R-H…. query_1 TRUE 0.0000000 1823 1676 438 0.2613365 0.2402633 REAC:R-HSA-1643685 REAC Disease 10777 710 REAC:0000000 query_1 TRUE 0.0000000 52 1676 42 0.0250597 0.8076923 REAC:R-HSA-69613 REAC p53-Independent G1/S DNA damage checkpoint 10777 2579 REAC:R-H…. query_1 TRUE 0.0000000 52 1676 42 0.0250597 0.8076923 REAC:R-HSA-69610 REAC p53-Independent DNA Damage Response 10777 2578 REAC:R-H…. query_1 TRUE 0.0000000 52 1676 42 0.0250597 0.8076923 REAC:R-HSA-69601 REAC Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 10777 2481 REAC:R-H…. query_1 TRUE 0.0000000 86 1676 56 0.0334129 0.6511628 REAC:R-HSA-450531 REAC Regulation of mRNA stability by proteins that bind AU-rich elements 10777 1928 REAC:R-H…. query_1 TRUE 0.0000000 205 1676 94 0.0560859 0.4585366 REAC:R-HSA-5357801 REAC Programmed Cell Death 10777 1713 REAC:0000000 query_1 TRUE 0.0000000 176 1676 85 0.0507160 0.4829545 REAC:R-HSA-109581 REAC Apoptosis 10777 152 REAC:R-H…. query_1 TRUE 0.0000000 53 1676 42 0.0250597 0.7924528 REAC:R-HSA-169911 REAC Regulation of Apoptosis 10777 1871 REAC:R-H…. query_1 TRUE 0.0000000 60 1676 45 0.0268496 0.7500000 REAC:R-HSA-5607761 REAC Dectin-1 mediated noncanonical NF-kB signaling 10777 435 REAC:R-H…. query_1 TRUE 0.0000000 60 1676 45 0.0268496 0.7500000 REAC:R-HSA-5610785 REAC GLI3 is processed to GLI3R by the proteasome 10777 962 REAC:R-H…. query_1 TRUE 0.0000000 60 1676 45 0.0268496 0.7500000 REAC:R-HSA-5610783 REAC Degradation of GLI2 by the proteasome 10777 689 REAC:R-H…. query_1 TRUE 0.0000000 65 1676 47 0.0280430 0.7230769 REAC:R-HSA-5358346 REAC Hedgehog ligand biogenesis 10777 1056 REAC:R-H…. query_1 TRUE 0.0000000 75 1676 51 0.0304296 0.6800000 REAC:R-HSA-1234174 REAC Cellular response to hypoxia 10777 323 REAC:R-H…. query_1 TRUE 0.0000000 73 1676 50 0.0298329 0.6849315 REAC:R-HSA-69017 REAC CDK-mediated phosphorylation and removal of Cdc6 10777 260 REAC:R-H…. query_1 TRUE 0.0000000 130 1676 70 0.0417661 0.5384615 REAC:R-HSA-69206 REAC G1/S Transition 10777 948 REAC:R-H…. query_1 TRUE 0.0000000 54 1676 42 0.0250597 0.7777778 REAC:R-HSA-8941858 REAC Regulation of RUNX3 expression and activity 10777 1898 REAC:R-H…. query_1 TRUE 0.0000000 92 1676 57 0.0340095 0.6195652 REAC:R-HSA-69052 REAC Switching of origins to a post-replicative state 10777 2234 REAC:R-H…. query_1 TRUE 0.0000000 71 1676 49 0.0292363 0.6901408 REAC:R-HSA-68949 REAC Orc1 removal from chromatin 10777 1556 REAC:R-H…. query_1 TRUE 0.0000000 59 1676 44 0.0262530 0.7457627 REAC:R-HSA-5676590 REAC NIK–>noncanonical NF-kB signaling 10777 1443 REAC:R-H…. query_1 TRUE 0.0000000 90 1676 56 0.0334129 0.6222222 REAC:R-HSA-1236974 REAC ER-Phagosome pathway 10777 786 REAC:R-H…. query_1 TRUE 0.0000000 57 1676 43 0.0256563 0.7543860 REAC:R-HSA-4641258 REAC Degradation of DVL 10777 686 REAC:R-H…. query_1 TRUE 0.0000000 57 1676 43 0.0256563 0.7543860 REAC:R-HSA-69541 REAC Stabilization of p53 10777 2221 REAC:R-H…. query_1 TRUE 0.0000000 55 1676 42 0.0250597 0.7636364 REAC:R-HSA-4641257 REAC Degradation of AXIN 10777 685 REAC:R-H…. query_1 TRUE 0.0000000 60 1676 44 0.0262530 0.7333333 REAC:R-HSA-5610780 REAC Degradation of GLI1 by the proteasome 10777 688 REAC:R-H…. query_1 TRUE 0.0000000 83 1676 53 0.0316229 0.6385542 REAC:R-HSA-195253 REAC Degradation of beta-catenin by the destruction complex 10777 690 REAC:R-H…. query_1 TRUE 0.0000000 101 1676 59 0.0352029 0.5841584 REAC:R-HSA-9755511 REAC KEAP1-NFE2L2 pathway 10777 1220 REAC:R-H…. query_1 TRUE 0.0000000 82 1676 52 0.0310263 0.6341463 REAC:R-HSA-69202 REAC Cyclin E associated events during G1/S transition 10777 400 REAC:R-H…. query_1 TRUE 0.0000000 105 1676 60 0.0357995 0.5714286 REAC:R-HSA-1236975 REAC Antigen processing-Cross presentation 10777 147 REAC:R-H…. query_1 TRUE 0.0000000 67 1676 46 0.0274463 0.6865672 REAC:R-HSA-1169091 REAC Activation of NF-kappaB in B cells 10777 83 REAC:R-H…. query_1 TRUE 0.0000000 121 1676 65 0.0387828 0.5371901 REAC:R-HSA-69239 REAC Synthesis of DNA 10777 2245 REAC:R-H…. query_1 TRUE 0.0000000 354 1676 128 0.0763723 0.3615819 REAC:R-HSA-9679506 REAC SARS-CoV Infections 10777 1990 REAC:R-H…. query_1 TRUE 0.0000000 81 1676 51 0.0304296 0.6296296 REAC:R-HSA-9013694 REAC Signaling by NOTCH4 10777 2158 REAC:R-H…. query_1 TRUE 0.0000000 84 1676 52 0.0310263 0.6190476 REAC:R-HSA-69656 REAC Cyclin A:Cdk2-associated events at S phase entry 10777 398 REAC:R-H…. query_1 TRUE 0.0000000 162 1676 77 0.0459427 0.4753086 REAC:R-HSA-69242 REAC S Phase 10777 1989 REAC:R-H…. query_1 TRUE 0.0000000 49 1676 38 0.0226730 0.7755102 REAC:R-HSA-1236978 REAC Cross-presentation of soluble exogenous antigens (endosomes) 10777 395 REAC:R-H…. query_1 TRUE 0.0000000 147 1676 72 0.0429594 0.4897959 REAC:R-HSA-453279 REAC Mitotic G1 phase and G1/S transition 10777 1400 REAC:R-H…. query_1 TRUE 0.0000000 125 1676 65 0.0387828 0.5200000 REAC:R-HSA-162909 REAC Host Interactions of HIV factors 10777 1073 REAC:R-H…. query_1 TRUE 0.0000000 228 1676 94 0.0560859 0.4122807 REAC:R-HSA-68882 REAC Mitotic Anaphase 10777 1399 REAC:R-H…. query_1 TRUE 0.0000000 229 1676 94 0.0560859 0.4104803 REAC:R-HSA-2555396 REAC Mitotic Metaphase and Anaphase 10777 1402 REAC:R-H…. query_1 TRUE 0.0000000 178 1676 80 0.0477327 0.4494382 REAC:R-HSA-72163 REAC mRNA Splicing - Major Pathway 10777 2566 REAC:R-H…. query_1 TRUE 0.0000000 71 1676 46 0.0274463 0.6478873 REAC:R-HSA-8939902 REAC Regulation of RUNX2 expression and activity 10777 1897 REAC:R-H…. query_1 TRUE 0.0000000 224 1676 92 0.0548926 0.4107143 REAC:R-HSA-162906 REAC HIV Infection 10777 1044 REAC:R-H…. query_1 TRUE 0.0000000 89 1676 52 0.0310263 0.5842697 REAC:R-HSA-5687128 REAC MAPK6/MAPK4 signaling 10777 1287 REAC:R-H…. query_1 TRUE 0.0000000 78 1676 48 0.0286396 0.6153846 REAC:R-HSA-5619084 REAC ABC transporter disorders 10777 4 REAC:R-H…. query_1 TRUE 0.0000000 279 1676 105 0.0626492 0.3763441 REAC:R-HSA-9694516 REAC SARS-CoV-2 Infection 10777 2000 REAC:R-H…. query_1 TRUE 0.0000000 94 1676 53 0.0316229 0.5638298 REAC:R-HSA-8878159 REAC Transcriptional regulation by RUNX3 10777 2420 REAC:R-H…. query_1 TRUE 0.0000000 188 1676 81 0.0483294 0.4308511 REAC:R-HSA-2467813 REAC Separation of Sister Chromatids 10777 2081 REAC:R-H…. query_1 TRUE 0.0000000 66 1676 43 0.0256563 0.6515152 REAC:R-HSA-69580 REAC p53-Dependent G1/S DNA damage checkpoint 10777 2577 REAC:R-H…. query_1 TRUE 0.0000000 66 1676 43 0.0256563 0.6515152 REAC:R-HSA-69563 REAC p53-Dependent G1 DNA Damage Response 10777 2576 REAC:R-H…. query_1 TRUE 0.0000000 80 1676 48 0.0286396 0.6000000 REAC:R-HSA-1168372 REAC Downstream signaling events of B Cell Receptor (BCR) 10777 753 REAC:R-H…. query_1 TRUE 0.0000000 51 1676 37 0.0220764 0.7254902 REAC:R-HSA-9754678 REAC SARS-CoV-2 modulates host translation machinery 10777 2003 REAC:R-H…. query_1 TRUE 0.0000000 69 1676 44 0.0262530 0.6376812 REAC:R-HSA-8948751 REAC Regulation of PTEN stability and activity 10777 1894 REAC:R-H…. query_1 TRUE 0.0000000 64 1676 42 0.0250597 0.6562500 REAC:R-HSA-4608870 REAC Asymmetric localization of PCP proteins 10777 177 REAC:R-H…. query_1 TRUE 0.0000000 186 1676 80 0.0477327 0.4301075 REAC:R-HSA-72172 REAC mRNA Splicing 10777 2565 REAC:R-H…. query_1 TRUE 0.0000000 67 1676 43 0.0256563 0.6417910 REAC:R-HSA-5658442 REAC Regulation of RAS by GAPs 10777 1895 REAC:R-H…. query_1 TRUE 0.0000000 87 1676 50 0.0298329 0.5747126 REAC:R-HSA-5389840 REAC Mitochondrial translation elongation 10777 1395 REAC:R-H…. query_1 TRUE 0.0000000 118 1676 60 0.0357995 0.5084746 REAC:R-HSA-8878166 REAC Transcriptional regulation by RUNX2 10777 2419 REAC:R-H…. query_1 TRUE 0.0000000 1093 1676 277 0.1652745 0.2534309 REAC:R-HSA-168249 REAC Innate Immune System 10777 1144 REAC:R-H…. query_1 TRUE 0.0000000 68 1676 43 0.0256563 0.6323529 REAC:R-HSA-69615 REAC G1/S DNA Damage Checkpoints 10777 947 REAC:R-H…. query_1 TRUE 0.0000000 92 1676 51 0.0304296 0.5543478 REAC:R-HSA-4086400 REAC PCP/CE pathway 10777 1571 REAC:R-H…. query_1 TRUE 0.0000000 87 1676 49 0.0292363 0.5632184 REAC:R-HSA-5419276 REAC Mitochondrial translation termination 10777 1397 REAC:R-H…. query_1 TRUE 0.0000000 87 1676 49 0.0292363 0.5632184 REAC:R-HSA-5368286 REAC Mitochondrial translation initiation 10777 1396 REAC:R-H…. query_1 TRUE 0.0000000 196 1676 81 0.0483294 0.4132653 REAC:R-HSA-69275 REAC G2/M Transition 10777 954 REAC:R-H…. query_1 TRUE 0.0000000 57 1676 38 0.0226730 0.6666667 REAC:R-HSA-6799198 REAC Complex I biogenesis 10777 371 REAC:R-H…. query_1 TRUE 0.0000000 198 1676 81 0.0483294 0.4090909 REAC:R-HSA-453274 REAC Mitotic G2-G2/M phases 10777 1401 REAC:R-H…. query_1 TRUE 0.0000000 93 1676 50 0.0298329 0.5376344 REAC:R-HSA-5368287 REAC Mitochondrial translation 10777 1394 REAC:R-H…. query_1 TRUE 0.0000000 103 1676 53 0.0316229 0.5145631 REAC:R-HSA-382556 REAC ABC-family proteins mediated transport 10777 6 REAC:R-H…. query_1 TRUE 0.0000000 97 1676 51 0.0304296 0.5257732 REAC:R-HSA-5607764 REAC CLEC7A (Dectin-1) signaling 10777 263 REAC:R-H…. query_1 TRUE 0.0000000 549 1676 160 0.0954654 0.2914390 REAC:R-HSA-69278 REAC Cell Cycle, Mitotic 10777 310 REAC:R-H…. query_1 TRUE 0.0000000 100 1676 51 0.0304296 0.5100000 REAC:R-HSA-5668541 REAC TNFR2 non-canonical NF-kB pathway 10777 2315 REAC:R-H…. query_1 TRUE 0.0000000 101 1676 51 0.0304296 0.5049505 REAC:R-HSA-9020702 REAC Interleukin-1 signaling 10777 1173 REAC:R-H…. query_1 TRUE 0.0000000 237 1676 88 0.0525060 0.3713080 REAC:R-HSA-72203 REAC Processing of Capped Intron-Containing Pre-mRNA 10777 1706 REAC:R-H…. query_1 TRUE 0.0000000 417 1676 130 0.0775656 0.3117506 REAC:R-HSA-5663202 REAC Diseases of signal transduction by growth factor receptors and second messengers 10777 735 REAC:R-H…. query_1 TRUE 0.0000000 101 1676 50 0.0298329 0.4950495 REAC:R-HSA-5689603 REAC UCH proteinases 10777 2477 REAC:R-H…. query_1 TRUE 0.0000000 85 1676 45 0.0268496 0.5294118 REAC:R-HSA-5632684 REAC Hedgehog ‘on’ state 10777 1055 REAC:R-H…. query_1 TRUE 0.0000000 98 1676 49 0.0292363 0.5000000 REAC:R-HSA-202424 REAC Downstream TCR signaling 10777 751 REAC:R-H…. query_1 TRUE 0.0000000 138 1676 60 0.0357995 0.4347826 REAC:R-HSA-6807070 REAC PTEN Regulation 10777 1614 REAC:R-H…. query_1 TRUE 0.0000000 679 1676 182 0.1085919 0.2680412 REAC:R-HSA-1640170 REAC Cell Cycle 10777 308 REAC:0000000 query_1 TRUE 0.0000000 113 1676 52 0.0310263 0.4601770 REAC:R-HSA-5610787 REAC Hedgehog ‘off’ state 10777 1054 REAC:R-H…. query_1 TRUE 0.0000000 197 1676 73 0.0435561 0.3705584 REAC:R-HSA-9705683 REAC SARS-CoV-2-host interactions 10777 2006 REAC:R-H…. query_1 TRUE 0.0000000 2041 1676 429 0.2559666 0.2101911 REAC:R-HSA-168256 REAC Immune System 10777 1110 REAC:0000000 query_1 TRUE 0.0000000 289 1676 94 0.0560859 0.3252595 REAC:R-HSA-69620 REAC Cell Cycle Checkpoints 10777 309 REAC:R-H…. query_1 TRUE 0.0000000 408 1676 120 0.0715990 0.2941176 REAC:R-HSA-68886 REAC M Phase 10777 1278 REAC:R-H…. query_1 TRUE 0.0000000 167 1676 64 0.0381862 0.3832335 REAC:R-HSA-69481 REAC G2/M Checkpoints 10777 951 REAC:R-H…. query_1 TRUE 0.0000000 120 1676 51 0.0304296 0.4250000 REAC:R-HSA-202403 REAC TCR signaling 10777 2292 REAC:R-H…. query_1 TRUE 0.0000000 139 1676 56 0.0334129 0.4028777 REAC:R-HSA-446652 REAC Interleukin-1 family signaling 10777 1171 REAC:R-H…. query_1 TRUE 0.0000000 143 1676 57 0.0340095 0.3986014 REAC:R-HSA-68867 REAC Assembly of the pre-replicative complex 10777 174 REAC:R-H…. query_1 TRUE 0.0000000 143 1676 57 0.0340095 0.3986014 REAC:R-HSA-3858494 REAC Beta-catenin independent WNT signaling 10777 207 REAC:R-H…. query_1 TRUE 0.0000000 149 1676 58 0.0346062 0.3892617 REAC:R-HSA-5358351 REAC Signaling by Hedgehog 10777 2135 REAC:R-H…. query_1 TRUE 0.0000000 188 1676 67 0.0399761 0.3563830 REAC:R-HSA-69306 REAC DNA Replication 10777 424 REAC:0000000 query_1 TRUE 0.0000000 160 1676 60 0.0357995 0.3750000 REAC:R-HSA-69002 REAC DNA Replication Pre-Initiation 10777 425 REAC:R-H…. query_1 TRUE 0.0000000 51 1676 29 0.0173031 0.5686275 REAC:R-HSA-72165 REAC mRNA Splicing - Minor Pathway 10777 2567 REAC:R-H…. query_1 TRUE 0.0000000 84 1676 39 0.0232697 0.4642857 REAC:R-HSA-5628897 REAC TP53 Regulates Metabolic Genes 10777 2317 REAC:R-H…. query_1 TRUE 0.0000000 704 1676 175 0.1044153 0.2485795 REAC:R-HSA-1280215 REAC Cytokine Signaling in Immune system 10777 404 REAC:R-H…. query_1 TRUE 0.0000000 38 1676 24 0.0143198 0.6315789 REAC:R-HSA-8950505 REAC Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 10777 988 REAC:R-H…. query_1 TRUE 0.0000000 136 1676 52 0.0310263 0.3823529 REAC:R-HSA-5621481 REAC C-type lectin receptors (CLRs) 10777 249 REAC:R-H…. query_1 TRUE 0.0000000 1116 1676 250 0.1491647 0.2240143 REAC:R-HSA-1266738 REAC Developmental Biology 10777 703 REAC:0000000 query_1 TRUE 0.0000000 305 1676 89 0.0531026 0.2918033 REAC:R-HSA-446203 REAC Asparagine N-linked glycosylation 10777 163 REAC:R-H…. query_1 TRUE 0.0000000 1415 1676 300 0.1789976 0.2120141 REAC:R-HSA-597592 REAC Post-translational protein modification 10777 1686 REAC:R-H…. query_1 TRUE 0.0000000 239 1676 74 0.0441527 0.3096234 REAC:R-HSA-8951664 REAC Neddylation 10777 1474 REAC:R-H…. query_1 TRUE 0.0000000 109 1676 43 0.0256563 0.3944954 REAC:R-HSA-5696398 REAC Nucleotide Excision Repair 10777 1536 REAC:R-H…. query_1 TRUE 0.0000000 233 1676 72 0.0429594 0.3090129 REAC:R-HSA-157118 REAC Signaling by NOTCH 10777 2149 REAC:R-H…. query_1 TRUE 0.0000000 359 1676 99 0.0590692 0.2757660 REAC:R-HSA-3700989 REAC Transcriptional Regulation by TP53 10777 2413 REAC:R-H…. query_1 TRUE 0.0000000 47 1676 25 0.0149165 0.5319149 REAC:R-HSA-9020591 REAC Interleukin-12 signaling 10777 1176 REAC:R-H…. query_1 TRUE 0.0000000 57 1676 28 0.0167064 0.4912281 REAC:R-HSA-447115 REAC Interleukin-12 family signaling 10777 1175 REAC:R-H…. query_1 TRUE 0.0000001 28 1676 18 0.0107399 0.6428571 REAC:R-HSA-389957 REAC Prefoldin mediated transfer of substrate to CCT/TriC 10777 1698 REAC:R-H…. query_1 TRUE 0.0000001 173 1676 57 0.0340095 0.3294798 REAC:R-HSA-5619115 REAC Disorders of transmembrane transporters 10777 740 REAC:R-H…. query_1 TRUE 0.0000001 136 1676 48 0.0286396 0.3529412 REAC:R-HSA-2871837 REAC FCERI mediated NF-kB activation 10777 850 REAC:R-H…. query_1 TRUE 0.0000001 460 1676 117 0.0698091 0.2543478 REAC:R-HSA-449147 REAC Signaling by Interleukins 10777 2138 REAC:R-H…. query_1 TRUE 0.0000002 130 1676 46 0.0274463 0.3538462 REAC:R-HSA-8939236 REAC RUNX1 regulates transcription of genes involved in differentiation of HSCs 10777 1829 REAC:R-H…. query_1 TRUE 0.0000003 84 1676 34 0.0202864 0.4047619 REAC:R-HSA-5696399 REAC Global Genome Nucleotide Excision Repair (GG-NER) 10777 993 REAC:R-H…. query_1 TRUE 0.0000003 252 1676 73 0.0435561 0.2896825 REAC:R-HSA-1257604 REAC PIP3 activates AKT signaling 10777 1591 REAC:R-H…. query_1 TRUE 0.0000004 33 1676 19 0.0113365 0.5757576 REAC:R-HSA-389958 REAC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 10777 389 REAC:R-H…. query_1 TRUE 0.0000005 155 1676 51 0.0304296 0.3290323 REAC:R-HSA-199977 REAC ER to Golgi Anterograde Transport 10777 785 REAC:R-H…. query_1 TRUE 0.0000005 186 1676 58 0.0346062 0.3118280 REAC:R-HSA-948021 REAC Transport to the Golgi and subsequent modification 10777 2467 REAC:R-H…. query_1 TRUE 0.0000005 53 1676 25 0.0149165 0.4716981 REAC:R-HSA-9700206 REAC Signaling by ALK in cancer 10777 2096 REAC:R-H…. query_1 TRUE 0.0000005 53 1676 25 0.0149165 0.4716981 REAC:R-HSA-9725370 REAC Signaling by ALK fusions and activated point mutants 10777 2095 REAC:R-H…. query_1 TRUE 0.0000005 380 1676 99 0.0590692 0.2605263 REAC:R-HSA-983169 REAC Class I MHC mediated antigen processing & presentation 10777 353 REAC:R-H…. query_1 TRUE 0.0000006 308 1676 84 0.0501193 0.2727273 REAC:R-HSA-5683057 REAC MAPK family signaling cascades 10777 1282 REAC:R-H…. query_1 TRUE 0.0000007 57 1676 26 0.0155131 0.4561404 REAC:R-HSA-9694635 REAC Translation of Structural Proteins 10777 2435 REAC:R-H…. query_1 TRUE 0.0000007 57 1676 26 0.0155131 0.4561404 REAC:R-HSA-9772573 REAC Late SARS-CoV-2 Infection Events 10777 1243 REAC:R-H…. query_1 TRUE 0.0000010 221 1676 65 0.0387828 0.2941176 REAC:R-HSA-5689880 REAC Ub-specific processing proteases 10777 2479 REAC:R-H…. query_1 TRUE 0.0000012 264 1676 74 0.0441527 0.2803030 REAC:R-HSA-5673001 REAC RAF/MAP kinase cascade 10777 1749 REAC:R-H…. query_1 TRUE 0.0000012 269 1676 75 0.0447494 0.2788104 REAC:R-HSA-5684996 REAC MAPK1/MAPK3 signaling 10777 1285 REAC:R-H…. query_1 TRUE 0.0000021 24 1676 15 0.0089499 0.6250000 REAC:R-HSA-174048 REAC APC/C:Cdc20 mediated degradation of Cyclin B 10777 22 REAC:R-H…. query_1 TRUE 0.0000022 624 1676 144 0.0859189 0.2307692 REAC:R-HSA-199991 REAC Membrane Trafficking 10777 1338 REAC:R-H…. query_1 TRUE 0.0000025 158 1676 50 0.0298329 0.3164557 REAC:R-HSA-9609507 REAC Protein localization 10777 1722 REAC:0000000 query_1 TRUE 0.0000028 163 1676 51 0.0304296 0.3128834 REAC:R-HSA-983705 REAC Signaling by the B Cell Receptor (BCR) 10777 2202 REAC:R-H…. query_1 TRUE 0.0000030 57 1676 25 0.0149165 0.4385965 REAC:R-HSA-917937 REAC Iron uptake and transport 10777 1217 REAC:R-H…. query_1 TRUE 0.0000037 54 1676 24 0.0143198 0.4444444 REAC:R-HSA-109606 REAC Intrinsic Pathway for Apoptosis 10777 1208 REAC:R-H…. query_1 TRUE 0.0000040 10 1676 9 0.0053699 0.9000000 REAC:R-HSA-390450 REAC Folding of actin by CCT/TriC 10777 897 REAC:R-H…. query_1 TRUE 0.0000047 77 1676 30 0.0178998 0.3896104 REAC:R-HSA-6781827 REAC Transcription-Coupled Nucleotide Excision Repair (TC-NER) 10777 2408 REAC:R-H…. query_1 TRUE 0.0000061 149 1676 47 0.0280430 0.3154362 REAC:R-HSA-9612973 REAC Autophagy 10777 186 REAC:0000000 query_1 TRUE 0.0000063 38 1676 19 0.0113365 0.5000000 REAC:R-HSA-5696394 REAC DNA Damage Recognition in GG-NER 10777 418 REAC:R-H…. query_1 TRUE 0.0000082 15 1676 11 0.0065632 0.7333333 REAC:R-HSA-111447 REAC Activation of BAD and translocation to mitochondria 10777 72 REAC:R-H…. query_1 TRUE 0.0000087 26 1676 15 0.0089499 0.5769231 REAC:R-HSA-179409 REAC APC-Cdc20 mediated degradation of Nek2A 10777 20 REAC:R-H…. query_1 TRUE 0.0000090 297 1676 78 0.0465394 0.2626263 REAC:R-HSA-5688426 REAC Deubiquitination 10777 702 REAC:R-H…. query_1 TRUE 0.0000103 502 1676 118 0.0704057 0.2350598 REAC:R-HSA-9006934 REAC Signaling by Receptor Tyrosine Kinases 10777 2177 REAC:R-H…. query_1 TRUE 0.0000139 232 1676 64 0.0381862 0.2758621 REAC:R-HSA-201681 REAC TCF dependent signaling in response to WNT 10777 2291 REAC:R-H…. query_1 TRUE 0.0000142 65 1676 26 0.0155131 0.4000000 REAC:R-HSA-1268020 REAC Mitochondrial protein import 10777 1390 REAC:R-H…. query_1 TRUE 0.0000153 30 1676 16 0.0095465 0.5333333 REAC:R-HSA-114452 REAC Activation of BH3-only proteins 10777 73 REAC:R-H…. query_1 TRUE 0.0000153 30 1676 16 0.0095465 0.5333333 REAC:R-HSA-8866652 REAC Synthesis of active ubiquitin: roles of E1 and E2 enzymes 10777 2270 REAC:R-H…. query_1 TRUE 0.0000174 292 1676 76 0.0453461 0.2602740 REAC:R-HSA-9006925 REAC Intracellular signaling by second messengers 10777 1206 REAC:R-H…. query_1 TRUE 0.0000211 78 1676 29 0.0173031 0.3717949 REAC:R-HSA-8852135 REAC Protein ubiquitination 10777 1725 REAC:R-H…. query_1 TRUE 0.0000256 125 1676 40 0.0238663 0.3200000 REAC:R-HSA-114608 REAC Platelet degranulation 10777 1674 REAC:R-H…. query_1 TRUE 0.0000260 63 1676 25 0.0149165 0.3968254 REAC:R-HSA-6782210 REAC Gap-filling DNA repair synthesis and ligation in TC-NER 10777 984 REAC:R-H…. query_1 TRUE 0.0000261 91 1676 32 0.0190931 0.3516484 REAC:R-HSA-15869 REAC Metabolism of nucleotides 10777 1356 REAC:R-H…. query_1 TRUE 0.0000268 87 1676 31 0.0184964 0.3563218 REAC:R-HSA-170834 REAC Signaling by TGF-beta Receptor Complex 10777 2183 REAC:R-H…. query_1 TRUE 0.0000284 52 1676 22 0.0131265 0.4230769 REAC:R-HSA-6781823 REAC Formation of TC-NER Pre-Incision Complex 10777 905 REAC:R-H…. query_1 TRUE 0.0000308 25 1676 14 0.0083532 0.5600000 REAC:R-HSA-6803529 REAC FGFR2 alternative splicing 10777 859 REAC:R-H…. query_1 TRUE 0.0000324 144 1676 44 0.0262530 0.3055556 REAC:R-HSA-8856828 REAC Clathrin-mediated endocytosis 10777 357 REAC:R-H…. query_1 TRUE 0.0000354 64 1676 25 0.0149165 0.3906250 REAC:R-HSA-6782135 REAC Dual incision in TC-NER 10777 770 REAC:R-H…. query_1 TRUE 0.0000369 328 1676 82 0.0489260 0.2500000 REAC:R-HSA-195721 REAC Signaling by WNT 10777 2188 REAC:R-H…. query_1 TRUE 0.0000372 35 1676 17 0.0101432 0.4857143 REAC:R-HSA-532668 REAC N-glycan trimming in the ER and Calnexin/Calreticulin cycle 10777 1427 REAC:R-H…. query_1 TRUE 0.0000403 182 1676 52 0.0310263 0.2857143 REAC:R-HSA-2454202 REAC Fc epsilon receptor (FCERI) signaling 10777 892 REAC:R-H…. query_1 TRUE 0.0000414 123 1676 39 0.0232697 0.3170732 REAC:R-HSA-2132295 REAC MHC class II antigen presentation 10777 1304 REAC:R-H…. query_1 TRUE 0.0000485 102 1676 34 0.0202864 0.3333333 REAC:R-HSA-6807878 REAC COPI-mediated anterograde transport 10777 267 REAC:R-H…. query_1 TRUE 0.0000498 29 1676 15 0.0089499 0.5172414 REAC:R-HSA-983170 REAC Antigen Presentation: Folding, assembly and peptide loading of class I MHC 10777 145 REAC:R-H…. query_1 TRUE 0.0000519 133 1676 41 0.0244630 0.3082707 REAC:R-HSA-8856688 REAC Golgi-to-ER retrograde transport 10777 1027 REAC:R-H…. query_1 TRUE 0.0000548 26 1676 14 0.0083532 0.5384615 REAC:R-HSA-191273 REAC Cholesterol biosynthesis 10777 334 REAC:R-H…. query_1 TRUE 0.0000568 54 1676 22 0.0131265 0.4074074 REAC:R-HSA-71406 REAC Pyruvate metabolism and Citric Acid (TCA) cycle 10777 1740 REAC:R-H…. query_1 TRUE 0.0000573 12 1676 9 0.0053699 0.7500000 REAC:R-HSA-9755779 REAC SARS-CoV-2 targets host intracellular signalling and regulatory pathways 10777 2005 REAC:R-H…. query_1 TRUE 0.0000579 36 1676 17 0.0101432 0.4722222 REAC:R-HSA-3299685 REAC Detoxification of Reactive Oxygen Species 10777 701 REAC:R-H…. query_1 TRUE 0.0000624 134 1676 41 0.0244630 0.3059701 REAC:R-HSA-1632852 REAC Macroautophagy 10777 1318 REAC:R-H…. query_1 TRUE 0.0000687 130 1676 40 0.0238663 0.3076923 REAC:R-HSA-76005 REAC Response to elevated platelet cytosolic Ca2+ 10777 1968 REAC:R-H…. query_1 TRUE 0.0000876 15 1676 10 0.0059666 0.6666667 REAC:R-HSA-9648895 REAC Response of EIF2AK1 (HRI) to heme deficiency 10777 1965 REAC:R-H…. query_1 TRUE 0.0001040 24 1676 13 0.0077566 0.5416667 REAC:R-HSA-9734009 REAC Defective Intrinsic Pathway for Apoptosis 10777 551 REAC:R-H…. query_1 TRUE 0.0001040 18 1676 11 0.0065632 0.6111111 REAC:R-HSA-9725371 REAC Nuclear events stimulated by ALK signaling in cancer 10777 1532 REAC:R-H…. query_1 TRUE 0.0001040 52 1676 21 0.0125298 0.4038462 REAC:R-HSA-9678108 REAC SARS-CoV-1 Infection 10777 1992 REAC:R-H…. query_1 TRUE 0.0001064 80 1676 28 0.0167064 0.3500000 REAC:R-HSA-9663891 REAC Selective autophagy 10777 2063 REAC:R-H…. query_1 TRUE 0.0001098 702 1676 150 0.0894988 0.2136752 REAC:R-HSA-194315 REAC Signaling by Rho GTPases 10777 2179 REAC:R-H…. query_1 TRUE 0.0001487 717 1676 152 0.0906921 0.2119944 REAC:R-HSA-9716542 REAC Signaling by Rho GTPases, Miro GTPases and RHOBTB3 10777 2180 REAC:R-H…. query_1 TRUE 0.0001525 13 1676 9 0.0053699 0.6923077 REAC:R-HSA-162658 REAC Golgi Cisternae Pericentriolar Stack Reorganization 10777 1026 REAC:R-H…. query_1 TRUE 0.0001525 13 1676 9 0.0053699 0.6923077 REAC:R-HSA-75035 REAC Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 10777 333 REAC:R-H…. query_1 TRUE 0.0001559 90 1676 30 0.0178998 0.3333333 REAC:R-HSA-2682334 REAC EPH-Ephrin signaling 10777 780 REAC:R-H…. query_1 TRUE 0.0001656 86 1676 29 0.0173031 0.3372093 REAC:R-HSA-2565942 REAC Regulation of PLK1 Activity at G2/M Transition 10777 1890 REAC:R-H…. query_1 TRUE 0.0001920 16 1676 10 0.0059666 0.6250000 REAC:R-HSA-2995383 REAC Initiation of Nuclear Envelope (NE) Reformation 10777 1141 REAC:R-H…. query_1 TRUE 0.0001968 22 1676 12 0.0071599 0.5454545 REAC:R-HSA-71403 REAC Citric acid cycle (TCA cycle) 10777 349 REAC:R-H…. query_1 TRUE 0.0001968 22 1676 12 0.0071599 0.5454545 REAC:R-HSA-5205685 REAC PINK1-PRKN Mediated Mitophagy 10777 1590 REAC:R-H…. query_1 TRUE 0.0002011 39 1676 17 0.0101432 0.4358974 REAC:R-HSA-110313 REAC Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 10777 2440 REAC:R-H…. query_1 TRUE 0.0002021 62 1676 23 0.0137232 0.3709677 REAC:R-HSA-9707564 REAC Cytoprotection by HMOX1 10777 405 REAC:R-H…. query_1 TRUE 0.0002068 32 1676 15 0.0089499 0.4687500 REAC:R-HSA-5656169 REAC Termination of translesion DNA synthesis 10777 2357 REAC:R-H…. query_1 TRUE 0.0002261 43 1676 18 0.0107399 0.4186047 REAC:R-HSA-5696395 REAC Formation of Incision Complex in GG-NER 10777 902 REAC:R-H…. query_1 TRUE 0.0002369 319 1676 77 0.0459427 0.2413793 REAC:R-HSA-195258 REAC RHO GTPase Effectors 10777 1754 REAC:R-H…. query_1 TRUE 0.0002501 29 1676 14 0.0083532 0.4827586 REAC:R-HSA-9683701 REAC Translation of Structural Proteins 10777 2434 REAC:R-H…. query_1 TRUE 0.0002530 11 1676 8 0.0047733 0.7272727 REAC:R-HSA-73817 REAC Purine ribonucleoside monophosphate biosynthesis 10777 1731 REAC:R-H…. query_1 TRUE 0.0002649 55 1676 21 0.0125298 0.3818182 REAC:R-HSA-5218859 REAC Regulated Necrosis 10777 1866 REAC:R-H…. query_1 TRUE 0.0002953 26 1676 13 0.0077566 0.5000000 REAC:R-HSA-389960 REAC Formation of tubulin folding intermediates by CCT/TriC 10777 921 REAC:R-H…. query_1 TRUE 0.0003270 72 1676 25 0.0149165 0.3472222 REAC:R-HSA-199992 REAC trans-Golgi Network Vesicle Budding 10777 2608 REAC:R-H…. query_1 TRUE 0.0003386 23 1676 12 0.0071599 0.5217391 REAC:R-HSA-9013418 REAC RHOBTB2 GTPase cycle 10777 1771 REAC:R-H…. query_1 TRUE 0.0003389 48 1676 19 0.0113365 0.3958333 REAC:R-HSA-73893 REAC DNA Damage Bypass 10777 417 REAC:R-H…. query_1 TRUE 0.0003397 98 1676 31 0.0184964 0.3163265 REAC:R-HSA-391251 REAC Protein folding 10777 1721 REAC:R-H…. query_1 TRUE 0.0003408 718 1676 150 0.0894988 0.2089136 REAC:R-HSA-5653656 REAC Vesicle-mediated transport 10777 2507 REAC:0000000 query_1 TRUE 0.0003672 20 1676 11 0.0065632 0.5500000 REAC:R-HSA-176412 REAC Phosphorylation of the APC/C 10777 1663 REAC:R-H…. query_1 TRUE 0.0003786 308 1676 74 0.0441527 0.2402597 REAC:R-HSA-983168 REAC Antigen processing: Ubiquitination & Proteasome degradation 10777 148 REAC:R-H…. query_1 TRUE 0.0003828 30 1676 14 0.0083532 0.4666667 REAC:R-HSA-167243 REAC Tat-mediated HIV elongation arrest and recovery 10777 2349 REAC:R-H…. query_1 TRUE 0.0003828 30 1676 14 0.0083532 0.4666667 REAC:R-HSA-167238 REAC Pausing and recovery of Tat-mediated HIV elongation 10777 1630 REAC:R-H…. query_1 TRUE 0.0003828 30 1676 14 0.0083532 0.4666667 REAC:R-HSA-110314 REAC Recognition of DNA damage by PCNA-containing replication complex 10777 1855 REAC:R-H…. query_1 TRUE 0.0004250 145 1676 41 0.0244630 0.2827586 REAC:R-HSA-162587 REAC HIV Life Cycle 10777 1045 REAC:R-H…. query_1 TRUE 0.0004672 27 1676 13 0.0077566 0.4814815 REAC:R-HSA-499943 REAC Interconversion of nucleotide di- and triphosphates 10777 1165 REAC:R-H…. query_1 TRUE 0.0004896 91 1676 29 0.0173031 0.3186813 REAC:R-HSA-381119 REAC Unfolded Protein Response (UPR) 10777 2486 REAC:R-H…. query_1 TRUE 0.0005753 42 1676 17 0.0101432 0.4047619 REAC:R-HSA-167200 REAC Formation of HIV-1 elongation complex containing HIV-1 Tat 10777 901 REAC:R-H…. query_1 TRUE 0.0005753 42 1676 17 0.0101432 0.4047619 REAC:R-HSA-167246 REAC Tat-mediated elongation of the HIV-1 transcript 10777 2350 REAC:R-H…. query_1 TRUE 0.0005753 42 1676 17 0.0101432 0.4047619 REAC:R-HSA-167169 REAC HIV Transcription Elongation 10777 1046 REAC:R-H…. query_1 TRUE 0.0005970 5 1676 5 0.0029833 1.0000000 REAC:R-HSA-3065676 REAC SUMO is conjugated to E1 (UBA2:SAE1) 10777 2041 REAC:R-H…. query_1 TRUE 0.0006079 12 1676 8 0.0047733 0.6666667 REAC:R-HSA-3371511 REAC HSF1 activation 10777 1051 REAC:R-H…. query_1 TRUE 0.0006104 58 1676 21 0.0125298 0.3620690 REAC:R-HSA-8866654 REAC E3 ubiquitin ligases ubiquitinate target proteins 10777 773 REAC:R-H…. query_1 TRUE 0.0006231 21 1676 11 0.0065632 0.5238095 REAC:R-HSA-8862803 REAC Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models 10777 699 REAC:R-H…. query_1 TRUE 0.0006231 21 1676 11 0.0065632 0.5238095 REAC:R-HSA-141430 REAC Inactivation of APC/C via direct inhibition of the APC/C complex 10777 1116 REAC:R-H…. query_1 TRUE 0.0006231 21 1676 11 0.0065632 0.5238095 REAC:R-HSA-141405 REAC Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 10777 1139 REAC:R-H…. query_1 TRUE 0.0006231 21 1676 11 0.0065632 0.5238095 REAC:R-HSA-8863678 REAC Neurodegenerative Diseases 10777 1502 REAC:R-H…. query_1 TRUE 0.0006813 18 1676 10 0.0059666 0.5555556 REAC:R-HSA-6804114 REAC TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 10777 2325 REAC:R-H…. query_1 TRUE 0.0008142 55 1676 20 0.0119332 0.3636364 REAC:R-HSA-9639288 REAC Amino acids regulate mTORC1 10777 136 REAC:R-H…. query_1 TRUE 0.0008559 32 1676 14 0.0083532 0.4375000 REAC:R-HSA-167290 REAC Pausing and recovery of HIV elongation 10777 1629 REAC:R-H…. query_1 TRUE 0.0008559 32 1676 14 0.0083532 0.4375000 REAC:R-HSA-70263 REAC Gluconeogenesis 10777 998 REAC:R-H…. query_1 TRUE 0.0008559 32 1676 14 0.0083532 0.4375000 REAC:R-HSA-167287 REAC HIV elongation arrest and recovery 10777 1048 REAC:R-H…. query_1 TRUE 0.0008711 25 1676 12 0.0071599 0.4800000 REAC:R-HSA-5696397 REAC Gap-filling DNA repair synthesis and ligation in GG-NER 10777 983 REAC:R-H…. query_1 TRUE 0.0009624 36 1676 15 0.0089499 0.4166667 REAC:R-HSA-8964043 REAC Plasma lipoprotein clearance 10777 1667 REAC:R-H…. query_1 TRUE 0.0009744 64 1676 22 0.0131265 0.3437500 REAC:R-HSA-5654738 REAC Signaling by FGFR2 10777 2121 REAC:R-H…. query_1 TRUE 0.0010351 22 1676 11 0.0065632 0.5000000 REAC:R-HSA-9613829 REAC Chaperone Mediated Autophagy 10777 330 REAC:R-H…. query_1 TRUE 0.0010351 22 1676 11 0.0065632 0.5000000 REAC:R-HSA-167242 REAC Abortive elongation of HIV-1 transcript in the absence of Tat 10777 47 REAC:R-H…. query_1 TRUE 0.0010605 44 1676 17 0.0101432 0.3863636 REAC:R-HSA-167152 REAC Formation of HIV elongation complex in the absence of HIV Tat 10777 900 REAC:R-H…. query_1 TRUE 0.0010605 132 1676 37 0.0220764 0.2803030 REAC:R-HSA-162599 REAC Late Phase of HIV Life Cycle 10777 1242 REAC:R-H…. query_1 TRUE 0.0010605 44 1676 17 0.0101432 0.3863636 REAC:R-HSA-2173789 REAC TGF-beta receptor signaling activates SMADs 10777 2298 REAC:R-H…. query_1 TRUE 0.0010720 48 1676 18 0.0107399 0.3750000 REAC:R-HSA-437239 REAC Recycling pathway of L1 10777 1861 REAC:R-H…. query_1 TRUE 0.0011074 236 1676 58 0.0346062 0.2457627 REAC:R-HSA-8878171 REAC Transcriptional regulation by RUNX1 10777 2418 REAC:R-H…. query_1 TRUE 0.0011619 91 1676 28 0.0167064 0.3076923 REAC:R-HSA-390466 REAC Chaperonin-mediated protein folding 10777 331 REAC:R-H…. query_1 TRUE 0.0011722 19 1676 10 0.0059666 0.5263158 REAC:R-HSA-110320 REAC Translesion Synthesis by POLH 10777 2436 REAC:R-H…. query_1 TRUE 0.0012176 65 1676 22 0.0131265 0.3384615 REAC:R-HSA-73856 REAC RNA Polymerase II Transcription Termination 10777 1803 REAC:R-H…. query_1 TRUE 0.0012521 13 1676 8 0.0047733 0.6153846 REAC:R-HSA-879415 REAC Advanced glycosylation endproduct receptor signaling 10777 121 REAC:R-H…. query_1 TRUE 0.0012521 13 1676 8 0.0047733 0.6153846 REAC:R-HSA-209560 REAC NF-kB is activated and signals survival 10777 1435 REAC:R-H…. query_1 TRUE 0.0012595 16 1676 9 0.0053699 0.5625000 REAC:R-HSA-175474 REAC Assembly Of The HIV Virion 10777 166 REAC:R-H…. query_1 TRUE 0.0012595 16 1676 9 0.0053699 0.5625000 REAC:R-HSA-8866427 REAC VLDLR internalisation and degradation 10777 2501 REAC:R-H…. query_1 TRUE 0.0012902 192 1676 49 0.0292363 0.2552083 REAC:R-HSA-913531 REAC Interferon Signaling 10777 1167 REAC:R-H…. query_1 TRUE 0.0012942 26 1676 12 0.0071599 0.4615385 REAC:R-HSA-77387 REAC Insulin receptor recycling 10777 1150 REAC:R-H…. query_1 TRUE 0.0012942 37 1676 15 0.0089499 0.4054054 REAC:R-HSA-75105 REAC Fatty acyl-CoA biosynthesis 10777 891 REAC:R-H…. query_1 TRUE 0.0012942 37 1676 15 0.0089499 0.4054054 REAC:R-HSA-9694548 REAC Maturation of spike protein 10777 1333 REAC:R-H…. query_1 TRUE 0.0012942 37 1676 15 0.0089499 0.4054054 REAC:R-HSA-9013407 REAC RHOH GTPase cycle 10777 1777 REAC:R-H…. query_1 TRUE 0.0012942 26 1676 12 0.0071599 0.4615385 REAC:R-HSA-901042 REAC Calnexin/calreticulin cycle 10777 291 REAC:R-H…. query_1 TRUE 0.0013047 57 1676 20 0.0119332 0.3508772 REAC:R-HSA-3371497 REAC HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand 10777 1053 REAC:R-H…. query_1 TRUE 0.0015337 30 1676 13 0.0077566 0.4333333 REAC:R-HSA-9674555 REAC Signaling by CSF3 (G-CSF) 10777 2104 REAC:R-H…. query_1 TRUE 0.0015923 23 1676 11 0.0065632 0.4782609 REAC:R-HSA-9637690 REAC Response of Mtb to phagocytosis 10777 1967 REAC:R-H…. query_1 TRUE 0.0016207 116 1676 33 0.0196897 0.2844828 REAC:R-HSA-9006936 REAC Signaling by TGFB family members 10777 2185 REAC:R-H…. query_1 TRUE 0.0018586 46 1676 17 0.0101432 0.3695652 REAC:R-HSA-2173793 REAC Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 10777 2417 REAC:R-H…. query_1 TRUE 0.0018930 136 1676 37 0.0220764 0.2720588 REAC:R-HSA-5663220 REAC RHO GTPases Activate Formins 10777 1756 REAC:R-H…. query_1 TRUE 0.0019421 27 1676 12 0.0071599 0.4444444 REAC:R-HSA-5205647 REAC Mitophagy 10777 1398 REAC:R-H…. query_1 TRUE 0.0019421 27 1676 12 0.0071599 0.4444444 REAC:R-HSA-2173795 REAC Downregulation of SMAD2/3:SMAD4 transcriptional activity 10777 749 REAC:R-H…. query_1 TRUE 0.0019421 27 1676 12 0.0071599 0.4444444 REAC:R-HSA-9635486 REAC Infection with Mycobacterium tuberculosis 10777 1122 REAC:R-H…. query_1 TRUE 0.0019760 76 1676 24 0.0143198 0.3157895 REAC:R-HSA-6806834 REAC Signaling by MET 10777 2145 REAC:R-H…. query_1 TRUE 0.0020002 85 1676 26 0.0155131 0.3058824 REAC:R-HSA-9679191 REAC Potential therapeutics for SARS 10777 1692 REAC:R-H…. query_1 TRUE 0.0021199 99 1676 29 0.0173031 0.2929293 REAC:R-HSA-6811434 REAC COPI-dependent Golgi-to-ER retrograde traffic 10777 265 REAC:R-H…. query_1 TRUE 0.0021913 31 1676 13 0.0077566 0.4193548 REAC:R-HSA-917977 REAC Transferrin endocytosis and recycling 10777 2428 REAC:R-H…. query_1 TRUE 0.0022460 11 1676 7 0.0041766 0.6363636 REAC:R-HSA-446107 REAC Type I hemidesmosome assembly 10777 2474 REAC:R-H…. query_1 TRUE 0.0022460 11 1676 7 0.0041766 0.6363636 REAC:R-HSA-1236977 REAC Endosomal/Vacuolar pathway 10777 804 REAC:R-H…. query_1 TRUE 0.0022460 11 1676 7 0.0041766 0.6363636 REAC:R-HSA-9664873 REAC Pexophagy 10777 1640 REAC:R-H…. query_1 TRUE 0.0023078 68 1676 22 0.0131265 0.3235294 REAC:R-HSA-204005 REAC COPII-mediated vesicle transport 10777 268 REAC:R-H…. query_1 TRUE 0.0023155 14 1676 8 0.0047733 0.5714286 REAC:R-HSA-1295596 REAC Spry regulation of FGF signaling 10777 2220 REAC:R-H…. query_1 TRUE 0.0023155 35 1676 14 0.0083532 0.4000000 REAC:R-HSA-432720 REAC Lysosome Vesicle Biogenesis 10777 1276 REAC:R-H…. query_1 TRUE 0.0023155 14 1676 8 0.0047733 0.5714286 REAC:R-HSA-8956320 REAC Nucleotide biosynthesis 10777 1537 REAC:R-H…. query_1 TRUE 0.0023848 24 1676 11 0.0065632 0.4583333 REAC:R-HSA-2173788 REAC Downregulation of TGF-beta receptor signaling 10777 750 REAC:R-H…. query_1 TRUE 0.0023848 24 1676 11 0.0065632 0.4583333 REAC:R-HSA-166208 REAC mTORC1-mediated signalling 10777 2570 REAC:R-H…. query_1 TRUE 0.0025865 6 1676 5 0.0029833 0.8333333 REAC:R-HSA-5336415 REAC Uptake and function of diphtheria toxin 10777 2490 REAC:R-H…. query_1 TRUE 0.0027823 28 1676 12 0.0071599 0.4285714 REAC:R-HSA-5213460 REAC RIPK1-mediated regulated necrosis 10777 1785 REAC:R-H…. query_1 TRUE 0.0027823 28 1676 12 0.0071599 0.4285714 REAC:R-HSA-5675482 REAC Regulation of necroptotic cell death 10777 1930 REAC:R-H…. query_1 TRUE 0.0028028 56 1676 19 0.0113365 0.3392857 REAC:R-HSA-429914 REAC Deadenylation-dependent mRNA decay 10777 433 REAC:R-H…. query_1 TRUE 0.0028785 78 1676 24 0.0143198 0.3076923 REAC:R-HSA-1169410 REAC Antiviral mechanism by IFN-stimulated genes 10777 151 REAC:R-H…. query_1 TRUE 0.0029988 720 1676 144 0.0859189 0.2000000 REAC:R-HSA-382551 REAC Transport of small molecules 10777 2463 REAC:0000000 query_1 TRUE 0.0030033 32 1676 13 0.0077566 0.4062500 REAC:R-HSA-2173796 REAC SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 10777 2031 REAC:R-H…. query_1 TRUE 0.0030033 32 1676 13 0.0077566 0.4062500 REAC:R-HSA-113418 REAC Formation of the Early Elongation Complex 10777 914 REAC:R-H…. query_1 TRUE 0.0030033 32 1676 13 0.0077566 0.4062500 REAC:R-HSA-167158 REAC Formation of the HIV-1 Early Elongation Complex 10777 916 REAC:R-H…. query_1 TRUE 0.0030972 4 1676 4 0.0023866 1.0000000 REAC:R-HSA-9694493 REAC Maturation of protein E 10777 1327 REAC:R-H…. query_1 TRUE 0.0030972 4 1676 4 0.0023866 1.0000000 REAC:R-HSA-9683683 REAC Maturation of protein E 10777 1326 REAC:R-H…. query_1 TRUE 0.0031188 74 1676 23 0.0137232 0.3108108 REAC:R-HSA-190236 REAC Signaling by FGFR 10777 2116 REAC:R-H…. query_1 TRUE 0.0031534 40 1676 15 0.0089499 0.3750000 REAC:R-HSA-3928662 REAC EPHB-mediated forward signaling 10777 783 REAC:R-H…. query_1 TRUE 0.0034079 70 1676 22 0.0131265 0.3142857 REAC:R-HSA-2995410 REAC Nuclear Envelope (NE) Reassembly 10777 1526 REAC:R-H…. query_1 TRUE 0.0034079 70 1676 22 0.0131265 0.3142857 REAC:R-HSA-1169408 REAC ISG15 antiviral mechanism 10777 1106 REAC:R-H…. query_1 TRUE 0.0034566 57 1676 19 0.0113365 0.3333333 REAC:R-HSA-75955 REAC RNA Polymerase II Transcription Elongation 10777 1799 REAC:R-H…. query_1 TRUE 0.0034566 809 1676 159 0.0948687 0.1965389 REAC:R-HSA-1280218 REAC Adaptive Immune System 10777 113 REAC:R-H…. query_1 TRUE 0.0034566 57 1676 19 0.0113365 0.3333333 REAC:R-HSA-112382 REAC Formation of RNA Pol II elongation complex 10777 903 REAC:R-H…. query_1 TRUE 0.0034667 25 1676 11 0.0065632 0.4400000 REAC:R-HSA-210991 REAC Basigin interactions 10777 198 REAC:R-H…. query_1 TRUE 0.0036748 53 1676 18 0.0107399 0.3396226 REAC:R-HSA-1655829 REAC Regulation of cholesterol biosynthesis by SREBP (SREBF) 10777 1912 REAC:R-H…. query_1 TRUE 0.0038788 49 1676 17 0.0101432 0.3469388 REAC:R-HSA-381070 REAC IRE1alpha activates chaperones 10777 1100 REAC:R-H…. query_1 TRUE 0.0039516 9 1676 6 0.0035800 0.6666667 REAC:R-HSA-8876493 REAC InlA-mediated entry of Listeria monocytogenes into host cells 10777 1142 REAC:R-H…. query_1 TRUE 0.0039516 9 1676 6 0.0035800 0.6666667 REAC:R-HSA-8849469 REAC PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 10777 1621 REAC:R-H…. query_1 TRUE 0.0041351 41 1676 15 0.0089499 0.3658537 REAC:R-HSA-5696400 REAC Dual Incision in GG-NER 10777 769 REAC:R-H…. query_1 TRUE 0.0042627 12 1676 7 0.0041766 0.5833333 REAC:R-HSA-5689877 REAC Josephin domain DUBs 10777 1219 REAC:R-H…. query_1 TRUE 0.0044643 123 1676 33 0.0196897 0.2682927 REAC:R-HSA-2500257 REAC Resolution of Sister Chromatid Cohesion 10777 1962 REAC:R-H…. query_1 TRUE 0.0046083 104 1676 29 0.0173031 0.2788462 REAC:R-HSA-8856825 REAC Cargo recognition for clathrin-mediated endocytosis 10777 297 REAC:R-H…. query_1 TRUE 0.0047747 109 1676 30 0.0178998 0.2752294 REAC:R-HSA-69618 REAC Mitotic Spindle Checkpoint 10777 1406 REAC:R-H…. query_1 TRUE 0.0050044 72 1676 22 0.0131265 0.3055556 REAC:R-HSA-1445148 REAC Translocation of SLC2A4 (GLUT4) to the plasma membrane 10777 2441 REAC:R-H…. query_1 TRUE 0.0054138 30 1676 12 0.0071599 0.4000000 REAC:R-HSA-3000157 REAC Laminin interactions 10777 1241 REAC:R-H…. query_1 TRUE 0.0054318 19 1676 9 0.0053699 0.4736842 REAC:R-HSA-9609523 REAC Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 10777 1147 REAC:R-H…. query_1 TRUE 0.0054318 19 1676 9 0.0053699 0.4736842 REAC:R-HSA-8964038 REAC LDL clearance 10777 1233 REAC:R-H…. query_1 TRUE 0.0054318 19 1676 9 0.0053699 0.4736842 REAC:R-HSA-5627117 REAC RHO GTPases Activate ROCKs 10777 1758 REAC:R-H…. query_1 TRUE 0.0054318 200 1676 48 0.0286396 0.2400000 REAC:R-HSA-68877 REAC Mitotic Prometaphase 10777 1404 REAC:R-H…. query_1 TRUE 0.0054933 38 1676 14 0.0083532 0.3684211 REAC:R-HSA-390471 REAC Association of TriC/CCT with target proteins during biosynthesis 10777 175 REAC:R-H…. query_1 TRUE 0.0061985 51 1676 17 0.0101432 0.3333333 REAC:R-HSA-9006927 REAC Signaling by Non-Receptor Tyrosine Kinases 10777 2163 REAC:R-H…. query_1 TRUE 0.0061985 51 1676 17 0.0101432 0.3333333 REAC:R-HSA-8848021 REAC Signaling by PTK6 10777 2170 REAC:R-H…. query_1 TRUE 0.0064652 23 1676 10 0.0059666 0.4347826 REAC:R-HSA-8949215 REAC Mitochondrial calcium ion transport 10777 1388 REAC:R-H…. query_1 TRUE 0.0065431 16 1676 8 0.0047733 0.5000000 REAC:R-HSA-110312 REAC Translesion synthesis by REV1 10777 2439 REAC:R-H…. query_1 TRUE 0.0065431 16 1676 8 0.0047733 0.5000000 REAC:R-HSA-193639 REAC p75NTR signals via NF-kB 10777 2584 REAC:R-H…. query_1 TRUE 0.0065431 16 1676 8 0.0047733 0.5000000 REAC:R-HSA-205043 REAC NRIF signals cell death from the nucleus 10777 1464 REAC:R-H…. query_1 TRUE 0.0065457 47 1676 16 0.0095465 0.3404255 REAC:R-HSA-381038 REAC XBP1(S) activates chaperone genes 10777 2537 REAC:R-H…. query_1 TRUE 0.0069878 7 1676 5 0.0029833 0.7142857 REAC:R-HSA-9637628 REAC Modulation by Mtb of host immune system 10777 1408 REAC:R-H…. query_1 TRUE 0.0069878 7 1676 5 0.0029833 0.7142857 REAC:R-HSA-3065678 REAC SUMO is transferred from E1 to E2 (UBE2I, UBC9) 10777 2043 REAC:R-H…. query_1 TRUE 0.0071423 107 1676 29 0.0173031 0.2710280 REAC:R-HSA-8957275 REAC Post-translational protein phosphorylation 10777 1687 REAC:R-H…. query_1 TRUE 0.0071463 39 1676 14 0.0083532 0.3589744 REAC:R-HSA-8853884 REAC Transcriptional Regulation by VENTX 10777 2414 REAC:R-H…. query_1 TRUE 0.0072695 35 1676 13 0.0077566 0.3714286 REAC:R-HSA-5663213 REAC RHO GTPases Activate WASPs and WAVEs 10777 1760 REAC:R-H…. query_1 TRUE 0.0072695 35 1676 13 0.0077566 0.3714286 REAC:R-HSA-9706574 REAC RHOBTB GTPase Cycle 10777 1769 REAC:R-H…. query_1 TRUE 0.0074968 13 1676 7 0.0041766 0.5384615 REAC:R-HSA-9637687 REAC Suppression of phagosomal maturation 10777 2232 REAC:R-H…. query_1 TRUE 0.0079741 10 1676 6 0.0035800 0.6000000 REAC:R-HSA-2465910 REAC MASTL Facilitates Mitotic Progression 10777 1288 REAC:R-H…. query_1 TRUE 0.0081355 20 1676 9 0.0053699 0.4500000 REAC:R-HSA-176407 REAC Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 10777 387 REAC:R-H…. query_1 TRUE 0.0087873 44 1676 15 0.0089499 0.3409091 REAC:R-HSA-9646399 REAC Aggrephagy 10777 123 REAC:R-H…. query_1 TRUE 0.0091830 24 1676 10 0.0059666 0.4166667 REAC:R-HSA-75876 REAC Synthesis of very long-chain fatty acyl-CoAs 10777 2282 REAC:R-H…. query_1 TRUE 0.0092489 40 1676 14 0.0083532 0.3500000 REAC:R-HSA-2426168 REAC Activation of gene expression by SREBF (SREBP) 10777 97 REAC:R-H…. query_1 TRUE 0.0094801 71 1676 21 0.0125298 0.2957746 REAC:R-HSA-909733 REAC Interferon alpha/beta signaling 10777 1168 REAC:R-H…. query_1 TRUE 0.0094830 53 1676 17 0.0101432 0.3207547 REAC:R-HSA-6811436 REAC COPI-independent Golgi-to-ER retrograde traffic 10777 266 REAC:R-H…. query_1 TRUE 0.0095555 36 1676 13 0.0077566 0.3611111 REAC:R-HSA-1222556 REAC ROS and RNS production in phagocytes 10777 1818 REAC:R-H…. query_1 TRUE 0.0101955 17 1676 8 0.0047733 0.4705882 REAC:R-HSA-5656121 REAC Translesion synthesis by POLI 10777 2437 REAC:R-H…. query_1 TRUE 0.0101955 17 1676 8 0.0047733 0.4705882 REAC:R-HSA-5655862 REAC Translesion synthesis by POLK 10777 2438 REAC:R-H…. query_1 TRUE 0.0106283 58 1676 18 0.0107399 0.3103448 REAC:R-HSA-3000171 REAC Non-integrin membrane-ECM interactions 10777 1517 REAC:R-H…. query_1 TRUE 0.0111423 202 1676 47 0.0280430 0.2326733 REAC:R-HSA-6811442 REAC Intra-Golgi and retrograde Golgi-to-ER traffic 10777 1202 REAC:R-H…. query_1 TRUE 0.0116905 54 1676 17 0.0101432 0.3148148 REAC:R-HSA-432722 REAC Golgi Associated Vesicle Biogenesis 10777 1025 REAC:R-H…. query_1 TRUE 0.0117333 41 1676 14 0.0083532 0.3414634 REAC:R-HSA-165159 REAC MTOR signalling 10777 1317 REAC:R-H…. query_1 TRUE 0.0117333 5 1676 4 0.0023866 0.8000000 REAC:R-HSA-8875513 REAC MET interacts with TNS proteins 10777 1300 REAC:R-H…. query_1 TRUE 0.0117333 5 1676 4 0.0023866 0.8000000 REAC:R-HSA-9683686 REAC Maturation of spike protein 10777 1332 REAC:R-H…. query_1 TRUE 0.0118299 21 1676 9 0.0053699 0.4285714 REAC:R-HSA-5651801 REAC PCNA-Dependent Long Patch Base Excision Repair 10777 1570 REAC:R-H…. query_1 TRUE 0.0123456 14 1676 7 0.0041766 0.5000000 REAC:R-HSA-174490 REAC Membrane binding and targetting of GAG proteins 10777 1339 REAC:R-H…. query_1 TRUE 0.0123456 37 1676 13 0.0077566 0.3513514 REAC:R-HSA-111465 REAC Apoptotic cleavage of cellular proteins 10777 155 REAC:R-H…. query_1 TRUE 0.0123456 14 1676 7 0.0041766 0.5000000 REAC:R-HSA-174495 REAC Synthesis And Processing Of GAG, GAGPOL Polyproteins 10777 2237 REAC:R-H…. query_1 TRUE 0.0125783 25 1676 10 0.0059666 0.4000000 REAC:R-HSA-9705462 REAC Inactivation of CSF3 (G-CSF) signaling 10777 1118 REAC:R-H…. query_1 TRUE 0.0125783 25 1676 10 0.0059666 0.4000000 REAC:R-HSA-69273 REAC Cyclin A/B1/B2 associated events during G2/M transition 10777 397 REAC:R-H…. query_1 TRUE 0.0125783 25 1676 10 0.0059666 0.4000000 REAC:R-HSA-110373 REAC Resolution of AP sites via the multiple-nucleotide patch replacement pathway 10777 1956 REAC:R-H…. query_1 TRUE 0.0126934 59 1676 18 0.0107399 0.3050847 REAC:R-HSA-6790901 REAC rRNA modification in the nucleus and cytosol 10777 2590 REAC:R-H…. query_1 TRUE 0.0140275 258 1676 57 0.0340095 0.2209302 REAC:R-HSA-76002 REAC Platelet activation, signaling and aggregation 10777 1672 REAC:R-H…. query_1 TRUE 0.0142381 11 1676 6 0.0035800 0.5454545 REAC:R-HSA-77588 REAC SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 10777 2021 REAC:R-H…. query_1 TRUE 0.0142381 11 1676 6 0.0035800 0.5454545 REAC:R-HSA-9708530 REAC Regulation of BACH1 activity 10777 1872 REAC:R-H…. query_1 TRUE 0.0142381 11 1676 6 0.0035800 0.5454545 REAC:R-HSA-196025 REAC Formation of annular gap junctions 10777 907 REAC:R-H…. query_1 TRUE 0.0146103 42 1676 14 0.0083532 0.3333333 REAC:R-HSA-5675221 REAC Negative regulation of MAPK pathway 10777 1488 REAC:R-H…. query_1 TRUE 0.0146103 42 1676 14 0.0083532 0.3333333 REAC:R-HSA-3769402 REAC Deactivation of the beta-catenin transactivating complex 10777 431 REAC:R-H…. query_1 TRUE 0.0146277 69 1676 20 0.0119332 0.2898551 REAC:R-HSA-167172 REAC Transcription of the HIV genome 10777 2407 REAC:R-H…. query_1 TRUE 0.0153455 51 1676 16 0.0095465 0.3137255 REAC:R-HSA-75153 REAC Apoptotic execution phase 10777 156 REAC:R-H…. query_1 TRUE 0.0155599 38 1676 13 0.0077566 0.3421053 REAC:R-HSA-445355 REAC Smooth Muscle Contraction 10777 2210 REAC:R-H…. query_1 TRUE 0.0164147 3 1676 3 0.0017900 1.0000000 REAC:R-HSA-5339700 REAC Signaling by TCF7L2 mutants 10777 2182 REAC:R-H…. query_1 TRUE 0.0164147 34 1676 12 0.0071599 0.3529412 REAC:R-HSA-9615710 REAC Late endosomal microautophagy 10777 1244 REAC:R-H…. query_1 TRUE 0.0164147 3 1676 3 0.0017900 1.0000000 REAC:R-HSA-77305 REAC Beta oxidation of palmitoyl-CoA to myristoyl-CoA 10777 206 REAC:R-H…. query_1 TRUE 0.0168581 56 1676 17 0.0101432 0.3035714 REAC:R-HSA-72187 REAC mRNA 3’-end processing 10777 2560 REAC:R-H…. query_1 TRUE 0.0170007 26 1676 10 0.0059666 0.3846154 REAC:R-HSA-3000170 REAC Syndecan interactions 10777 2236 REAC:R-H…. query_1 TRUE 0.0182448 61 1676 18 0.0107399 0.2950820 REAC:R-HSA-6796648 REAC TP53 Regulates Transcription of DNA Repair Genes 10777 2321 REAC:R-H…. query_1 TRUE 0.0186684 52 1676 16 0.0095465 0.3076923 REAC:R-HSA-9013405 REAC RHOD GTPase cycle 10777 1774 REAC:R-H…. query_1 TRUE 0.0186827 80 1676 22 0.0131265 0.2750000 REAC:R-HSA-674695 REAC RNA Polymerase II Pre-transcription Events 10777 1796 REAC:R-H…. query_1 TRUE 0.0189807 15 1676 7 0.0041766 0.4666667 REAC:R-HSA-430039 REAC mRNA decay by 5’ to 3’ exoribonuclease 10777 2569 REAC:R-H…. query_1 TRUE 0.0189807 15 1676 7 0.0041766 0.4666667 REAC:R-HSA-2173791 REAC TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 10777 2299 REAC:R-H…. query_1 TRUE 0.0217799 19 1676 8 0.0047733 0.4210526 REAC:R-HSA-8876384 REAC Listeria monocytogenes entry into host cells 10777 1257 REAC:R-H…. query_1 TRUE 0.0217799 19 1676 8 0.0047733 0.4210526 REAC:R-HSA-168927 REAC TICAM1, RIP1-mediated IKK complex recruitment 10777 2305 REAC:R-H…. query_1 TRUE 0.0221041 31 1676 11 0.0065632 0.3548387 REAC:R-HSA-917729 REAC Endosomal Sorting Complex Required For Transport (ESCRT) 10777 803 REAC:R-H…. query_1 TRUE 0.0227718 27 1676 10 0.0059666 0.3703704 REAC:R-HSA-1614635 REAC Sulfur amino acid metabolism 10777 2227 REAC:R-H…. query_1 TRUE 0.0227718 23 1676 9 0.0053699 0.3913043 REAC:R-HSA-1643713 REAC Signaling by EGFR in Cancer 10777 2107 REAC:R-H…. query_1 TRUE 0.0231658 449 1676 90 0.0536993 0.2004454 REAC:R-HSA-9012999 REAC RHO GTPase cycle 10777 1755 REAC:R-H…. query_1 TRUE 0.0234393 12 1676 6 0.0035800 0.5000000 REAC:R-HSA-9614399 REAC Regulation of localization of FOXO transcription factors 10777 1927 REAC:R-H…. query_1 TRUE 0.0234393 12 1676 6 0.0035800 0.5000000 REAC:R-HSA-190873 REAC Gap junction degradation 10777 980 REAC:R-H…. query_1 TRUE 0.0236476 72 1676 20 0.0119332 0.2777778 REAC:R-HSA-8854518 REAC AURKA Activation by TPX2 10777 37 REAC:R-H…. query_1 TRUE 0.0244139 40 1676 13 0.0077566 0.3250000 REAC:R-HSA-8875878 REAC MET promotes cell motility 10777 1301 REAC:R-H…. query_1 TRUE 0.0248556 49 1676 15 0.0089499 0.3061224 REAC:R-HSA-6791312 REAC TP53 Regulates Transcription of Cell Cycle Genes 10777 2319 REAC:R-H…. query_1 TRUE 0.0253383 87 1676 23 0.0137232 0.2643678 REAC:R-HSA-3371556 REAC Cellular response to heat stress 10777 322 REAC:R-H…. query_1 TRUE 0.0263877 36 1676 12 0.0071599 0.3333333 REAC:R-HSA-9687139 REAC Aberrant regulation of mitotic cell cycle due to RB1 defects 10777 44 REAC:R-H…. query_1 TRUE 0.0270156 9 1676 5 0.0029833 0.5555556 REAC:R-HSA-162592 REAC Integration of provirus 10777 1154 REAC:R-H…. query_1 TRUE 0.0270156 9 1676 5 0.0029833 0.5555556 REAC:R-HSA-381183 REAC ATF6 (ATF6-alpha) activates chaperone genes 10777 33 REAC:R-H…. query_1 TRUE 0.0270156 9 1676 5 0.0029833 0.5555556 REAC:R-HSA-2142688 REAC Synthesis of 5-eicosatetraenoic acids 10777 2242 REAC:R-H…. query_1 TRUE 0.0270156 9 1676 5 0.0029833 0.5555556 REAC:R-HSA-9636383 REAC Prevention of phagosomal-lysosomal fusion 10777 1704 REAC:R-H…. query_1 TRUE 0.0270156 9 1676 5 0.0029833 0.5555556 REAC:R-HSA-111453 REAC BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members 10777 194 REAC:R-H…. query_1 TRUE 0.0270156 9 1676 5 0.0029833 0.5555556 REAC:R-HSA-977347 REAC Serine biosynthesis 10777 2082 REAC:R-H…. query_1 TRUE 0.0270156 9 1676 5 0.0029833 0.5555556 REAC:R-HSA-167590 REAC Nef Mediated CD4 Down-regulation 10777 1475 REAC:R-H…. query_1 TRUE 0.0272655 6 1676 4 0.0023866 0.6666667 REAC:R-HSA-1237112 REAC Methionine salvage pathway 10777 1370 REAC:R-H…. query_1 TRUE 0.0272655 6 1676 4 0.0023866 0.6666667 REAC:R-HSA-8937144 REAC Aryl hydrocarbon receptor signalling 10777 162 REAC:R-H…. query_1 TRUE 0.0272655 6 1676 4 0.0023866 0.6666667 REAC:R-HSA-3000484 REAC Scavenging by Class F Receptors 10777 2059 REAC:R-H…. query_1 TRUE 0.0272655 6 1676 4 0.0023866 0.6666667 REAC:R-HSA-176417 REAC Phosphorylation of Emi1 10777 1660 REAC:R-H…. query_1 TRUE 0.0272655 6 1676 4 0.0023866 0.6666667 REAC:R-HSA-77288 REAC mitochondrial fatty acid beta-oxidation of unsaturated fatty acids 10777 2573 REAC:R-H…. query_1 TRUE 0.0273957 32 1676 11 0.0065632 0.3437500 REAC:R-HSA-69190 REAC DNA strand elongation 10777 428 REAC:R-H…. query_1 TRUE 0.0273957 16 1676 7 0.0041766 0.4375000 REAC:R-HSA-399954 REAC Sema3A PAK dependent Axon repulsion 10777 2066 REAC:R-H…. query_1 TRUE 0.0273957 32 1676 11 0.0065632 0.3437500 REAC:R-HSA-381042 REAC PERK regulates gene expression 10777 1576 REAC:R-H…. query_1 TRUE 0.0273957 32 1676 11 0.0065632 0.3437500 REAC:R-HSA-5626467 REAC RHO GTPases activate IQGAPs 10777 1762 REAC:R-H…. query_1 TRUE 0.0288079 28 1676 10 0.0059666 0.3571429 REAC:R-HSA-72086 REAC mRNA Capping 10777 2561 REAC:R-H…. query_1 TRUE 0.0288079 28 1676 10 0.0059666 0.3571429 REAC:R-HSA-162588 REAC Budding and maturation of HIV virion 10777 246 REAC:R-H…. query_1 TRUE 0.0292316 20 1676 8 0.0047733 0.4000000 REAC:R-HSA-9687136 REAC Aberrant regulation of mitotic exit in cancer due to RB1 defects 10777 45 REAC:R-H…. query_1 TRUE 0.0292316 20 1676 8 0.0047733 0.4000000 REAC:R-HSA-6807004 REAC Negative regulation of MET activity 10777 1489 REAC:R-H…. query_1 TRUE 0.0292316 20 1676 8 0.0047733 0.4000000 REAC:R-HSA-164938 REAC Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 10777 1480 REAC:R-H…. query_1 TRUE 0.0308858 74 1676 20 0.0119332 0.2702703 REAC:R-HSA-9013408 REAC RHOG GTPase cycle 10777 1776 REAC:R-H…. query_1 TRUE 0.0308858 74 1676 20 0.0119332 0.2702703 REAC:R-HSA-9013106 REAC RHOC GTPase cycle 10777 1773 REAC:R-H…. query_1 TRUE 0.0310050 55 1676 16 0.0095465 0.2909091 REAC:R-HSA-168643 REAC Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 10777 1542 REAC:R-H…. query_1 TRUE 0.0317963 84 1676 22 0.0131265 0.2619048 REAC:R-HSA-70326 REAC Glucose metabolism 10777 999 REAC:R-H…. query_1 TRUE 0.0320997 46 1676 14 0.0083532 0.3043478 REAC:R-HSA-69236 REAC G1 Phase 10777 946 REAC:R-H…. query_1 TRUE 0.0320997 46 1676 14 0.0083532 0.3043478 REAC:R-HSA-69231 REAC Cyclin D associated events in G1 10777 399 REAC:R-H…. query_1 TRUE 0.0349550 13 1676 6 0.0035800 0.4615385 REAC:R-HSA-975110 REAC TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 10777 2331 REAC:R-H…. query_1 TRUE 0.0349550 115 1676 28 0.0167064 0.2434783 REAC:R-HSA-9648025 REAC EML4 and NUDC in mitotic spindle formation 10777 779 REAC:R-H…. query_1 TRUE 0.0349550 13 1676 6 0.0035800 0.4615385 REAC:R-HSA-1679131 REAC Trafficking and processing of endosomal TLR 10777 2398 REAC:R-H…. query_1 TRUE 0.0349550 13 1676 6 0.0035800 0.4615385 REAC:R-HSA-209543 REAC p75NTR recruits signalling complexes 10777 2582 REAC:R-H…. query_1 TRUE 0.0360051 173 1676 39 0.0232697 0.2254335 REAC:R-HSA-8978868 REAC Fatty acid metabolism 10777 889 REAC:R-H…. query_1 TRUE 0.0385429 17 1676 7 0.0041766 0.4117647 REAC:R-HSA-5637815 REAC Signaling by Ligand-Responsive EGFR Variants in Cancer 10777 2142 REAC:R-H…. query_1 TRUE 0.0385429 17 1676 7 0.0041766 0.4117647 REAC:R-HSA-1236382 REAC Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 10777 381 REAC:R-H…. query_1 TRUE 0.0385429 25 1676 9 0.0053699 0.3600000 REAC:R-HSA-429947 REAC Deadenylation of mRNA 10777 432 REAC:R-H…. query_1 TRUE 0.0385429 17 1676 7 0.0041766 0.4117647 REAC:R-HSA-9694614 REAC Attachment and Entry 10777 180 REAC:R-H…. query_1 TRUE 0.0385429 25 1676 9 0.0053699 0.3600000 REAC:R-HSA-9664424 REAC Cell recruitment (pro-inflammatory response) 10777 313 REAC:R-H…. query_1 TRUE 0.0385429 25 1676 9 0.0053699 0.3600000 REAC:R-HSA-9660826 REAC Purinergic signaling in leishmaniasis infection 10777 1733 REAC:R-H…. query_1 TRUE 0.0388985 38 1676 12 0.0071599 0.3157895 REAC:R-HSA-9675126 REAC Diseases of mitotic cell cycle 10777 731 REAC:R-H…. query_1 TRUE 0.0392666 21 1676 8 0.0047733 0.3809524 REAC:R-HSA-5627123 REAC RHO GTPases activate PAKs 10777 1764 REAC:R-H…. query_1 TRUE 0.0398455 71 1676 19 0.0113365 0.2676056 REAC:R-HSA-174824 REAC Plasma lipoprotein assembly, remodeling, and clearance 10777 1666 REAC:R-H…. query_1 TRUE 0.0426995 34 1676 11 0.0065632 0.3235294 REAC:R-HSA-9772572 REAC Early SARS-CoV-2 Infection Events 10777 794 REAC:R-H…. query_1 TRUE 0.0435473 10 1676 5 0.0029833 0.5000000 REAC:R-HSA-3215018 REAC Processing and activation of SUMO 10777 1705 REAC:R-H…. query_1 TRUE 0.0435473 10 1676 5 0.0029833 0.5000000 REAC:R-HSA-111367 REAC SLBP independent Processing of Histone Pre-mRNAs 10777 2022 REAC:R-H…. query_1 TRUE 0.0462359 30 1676 10 0.0059666 0.3333333 REAC:R-HSA-182971 REAC EGFR downregulation 10777 776 REAC:R-H…. query_1 TRUE 0.0462359 30 1676 10 0.0059666 0.3333333 REAC:R-HSA-70268 REAC Pyruvate metabolism 10777 1739 REAC:R-H…. query_1 TRUE 0.0462359 30 1676 10 0.0059666 0.3333333 REAC:R-HSA-8874081 REAC MET activates PTK2 signaling 10777 1295 REAC:R-H…. query_1 TRUE 0.0493872 4 1676 3 0.0017900 0.7500000 REAC:R-HSA-6807047 REAC Cholesterol biosynthesis via desmosterol 10777 335 REAC:R-H…. query_1 TRUE 0.0493872 4 1676 3 0.0017900 0.7500000 REAC:R-HSA-6807062 REAC Cholesterol biosynthesis via lathosterol 10777 336 REAC:R-H…. query_1 TRUE 0.0493872 4 1676 3 0.0017900 0.7500000 REAC:R-HSA-446343 REAC Localization of the PINCH-ILK-PARVIN complex to focal adhesions 10777 1258 REAC:R-H…. query_1 TRUE 0.0493872 26 1676 9 0.0053699 0.3461538 REAC:R-HSA-77075 REAC RNA Pol II CTD phosphorylation and interaction with CE 10777 1787 REAC:R-H…. query_1 TRUE 0.0493872 4 1676 3 0.0017900 0.7500000 REAC:R-HSA-180689 REAC APOBEC3G mediated resistance to HIV-1 infection 10777 28 REAC:R-H…. query_1 TRUE 0.0493872 26 1676 9 0.0053699 0.3461538 REAC:R-HSA-167160 REAC RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 10777 1788 REAC:R-H…. query_1 TRUE 0.0000000 88 1342 77 0.0573770 0.8750000 WP:WP477 WP Cytoplasmic ribosomal proteins 7899 72 WP:000000 query_1 TRUE 0.0000000 62 1342 49 0.0365127 0.7903226 WP:WP183 WP Proteasome degradation 7899 105 WP:000000 query_1 TRUE 0.0000000 103 1342 60 0.0447094 0.5825243 WP:WP111 WP Electron transport chain: OXPHOS system in mitochondria 7899 353 WP:000000 query_1 TRUE 0.0000000 430 1342 148 0.1102832 0.3441860 WP:WP3888 WP VEGFA-VEGFR2 signaling pathway 7899 730 WP:000000 query_1 TRUE 0.0000000 154 1342 72 0.0536513 0.4675325 WP:WP4396 WP Nonalcoholic fatty liver disease 7899 588 WP:000000 query_1 TRUE 0.0000000 125 1342 61 0.0454545 0.4880000 WP:WP411 WP mRNA processing 7899 672 WP:000000 query_1 TRUE 0.0000000 50 1342 34 0.0253353 0.6800000 WP:WP107 WP Translation factors 7899 231 WP:000000 query_1 TRUE 0.0000000 42 1342 30 0.0223547 0.7142857 WP:WP4290 WP Metabolic reprogramming in colon cancer 7899 547 WP:000000 query_1 TRUE 0.0000000 56 1342 34 0.0253353 0.6071429 WP:WP4324 WP Mitochondrial complex I assembly model OXPHOS system 7899 634 WP:000000 query_1 TRUE 0.0000000 60 1342 33 0.0245902 0.5500000 WP:WP623 WP Oxidative phosphorylation 7899 238 WP:000000 query_1 TRUE 0.0000001 16 1342 14 0.0104322 0.8750000 WP:WP5027 WP nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell 7899 137 WP:000000 query_1 TRUE 0.0000065 71 1342 31 0.0230999 0.4366197 WP:WP2359 WP Parkin-ubiquitin proteasomal system pathway 7899 720 WP:000000 query_1 TRUE 0.0000235 64 1342 28 0.0208644 0.4375000 WP:WP4313 WP Ferroptosis 7899 366 WP:000000 query_1 TRUE 0.0000408 42 1342 21 0.0156483 0.5000000 WP:WP5220 WP Metabolic reprogramming in pancreatic cancer 7899 355 WP:000000 query_1 TRUE 0.0000784 47 1342 22 0.0163934 0.4680851 WP:WP4718 WP Cholesterol metabolism with Bloch and Kandutsch-Russell pathways 7899 200 WP:000000 query_1 TRUE 0.0000784 34 1342 18 0.0134128 0.5294118 WP:WP4922 WP Mitochondrial complex IV assembly 7899 549 WP:000000 query_1 TRUE 0.0000784 260 1342 74 0.0551416 0.2846154 WP:WP5124 WP Alzheimer’s disease 7899 77 WP:000000 query_1 TRUE 0.0001190 55 1342 24 0.0178838 0.4363636 WP:WP2272 WP Pathogenic Escherichia coli infection 7899 535 WP:000000 query_1 TRUE 0.0001279 18 1342 12 0.0089419 0.6666667 WP:WP78 WP TCA cycle (aka Krebs or citric acid cycle) 7899 51 WP:000000 query_1 TRUE 0.0001279 18 1342 12 0.0089419 0.6666667 WP:WP5193 WP Cholesterol synthesis disorders 7899 294 WP:000000 query_1 TRUE 0.0001832 53 1342 23 0.0171386 0.4339623 WP:WP2864 WP Apoptosis-related network due to altered Notch3 in ovarian cancer 7899 133 WP:000000 query_1 TRUE 0.0004598 12 1342 9 0.0067064 0.7500000 WP:WP4629 WP Aerobic glycolysis 7899 167 WP:000000 query_1 TRUE 0.0004598 17 1342 11 0.0081967 0.6470588 WP:WP1946 WP Cori cycle 7899 664 WP:000000 query_1 TRUE 0.0007257 15 1342 10 0.0074516 0.6666667 WP:WP197 WP Cholesterol biosynthesis pathway 7899 157 WP:000000 query_1 TRUE 0.0014669 71 1342 26 0.0193741 0.3661972 WP:WP1982 WP Sterol regulatory element-binding proteins (SREBP) signaling 7899 206 WP:000000 query_1 TRUE 0.0015250 45 1342 19 0.0141580 0.4222222 WP:WP534 WP Glycolysis and gluconeogenesis 7899 300 WP:000000 query_1 TRUE 0.0017490 11 1342 8 0.0059613 0.7272727 WP:WP5233 WP Arsenic metabolism and reactive oxygen species generation 7899 763 WP:000000 query_1 TRUE 0.0026789 214 1342 58 0.0432191 0.2710280 WP:WP4352 WP Ciliary landscape 7899 488 WP:000000 query_1 TRUE 0.0026789 90 1342 30 0.0223547 0.3333333 WP:WP2446 WP Retinoblastoma gene in cancer 7899 381 WP:000000 query_1 TRUE 0.0027942 120 1342 37 0.0275708 0.3083333 WP:WP179 WP Cell cycle 7899 207 WP:000000 query_1 TRUE 0.0034846 37 1342 16 0.0119225 0.4324324 WP:WP3614 WP Photodynamic therapy-induced HIF-1 survival signaling 7899 26 WP:000000 query_1 TRUE 0.0035084 48 1342 19 0.0141580 0.3958333 WP:WP410 WP Exercise-induced circadian regulation 7899 691 WP:000000 query_1 TRUE 0.0036438 27 1342 13 0.0096870 0.4814815 WP:WP3613 WP Photodynamic therapy-induced unfolded protein response 7899 693 WP:000000 query_1 TRUE 0.0048091 128 1342 38 0.0283159 0.2968750 WP:WP4217 WP Ebola virus infection in host 7899 738 WP:000000 query_1 TRUE 0.0072234 22 1342 11 0.0081967 0.5000000 WP:WP357 WP Fatty acid biosynthesis 7899 452 WP:000000 query_1 TRUE 0.0077280 16 1342 9 0.0067064 0.5625000 WP:WP2453 WP TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc) 7899 92 WP:000000 query_1 TRUE 0.0077280 16 1342 9 0.0067064 0.5625000 WP:WP4921 WP Mitochondrial complex III assembly 7899 711 WP:000000 query_1 TRUE 0.0081709 114 1342 34 0.0253353 0.2982456 WP:WP4659 WP Gastrin signaling pathway 7899 532 WP:000000 query_1 TRUE 0.0085440 8 1342 6 0.0044709 0.7500000 WP:WP2456 WP HIF1A and PPARG regulation of glycolysis 7899 727 WP:000000 query_1 TRUE 0.0087855 33 1342 14 0.0104322 0.4242424 WP:WP244 WP Alpha 6 beta 4 signaling pathway 7899 267 WP:000000 query_1 TRUE 0.0117142 11 1342 7 0.0052161 0.6363636 WP:WP5049 WP Glycolysis in senescence 7899 455 WP:000000 query_1 TRUE 0.0117884 6 1342 5 0.0037258 0.8333333 WP:WP4918 WP Cellular proteostasis 7899 37 WP:000000 query_1 TRUE 0.0123201 14 1342 8 0.0059613 0.5714286 WP:WP4724 WP Omega-9 fatty acid synthesis 7899 135 WP:000000 query_1 TRUE 0.0128367 131 1342 37 0.0275708 0.2824427 WP:WP366 WP TGF-beta signaling pathway 7899 54 WP:000000 query_1 TRUE 0.0142858 24 1342 11 0.0081967 0.4583333 WP:WP4925 WP Unfolded protein response 7899 453 WP:000000 query_1 TRUE 0.0169451 106 1342 31 0.0230999 0.2924528 WP:WP4932 WP 7q11.23 copy number variation syndrome 7899 29 WP:000000 query_1 TRUE 0.0179547 76 1342 24 0.0178838 0.3157895 WP:WP2037 WP Prolactin signaling pathway 7899 529 WP:000000 query_1 TRUE 0.0179547 9 1342 6 0.0044709 0.6666667 WP:WP5241 WP Mitochondrial beta-oxidation 7899 336 WP:000000 query_1 TRUE 0.0215206 77 1342 24 0.0178838 0.3116883 WP:WP4949 WP 16p11.2 proximal deletion syndrome 7899 45 WP:000000 query_1 TRUE 0.0224798 86 1342 26 0.0193741 0.3023256 WP:WP4018 WP Clear cell renal cell carcinoma pathways 7899 203 WP:000000 query_1 TRUE 0.0228185 22 1342 10 0.0074516 0.4545455 WP:WP4224 WP Purine metabolism and related disorders 7899 611 WP:000000 query_1 TRUE 0.0228185 22 1342 10 0.0074516 0.4545455 WP:WP3580 WP Methionine de novo and salvage pathway 7899 587 WP:000000 query_1 TRUE 0.0260984 96 1342 28 0.0208644 0.2916667 WP:WP4658 WP Small cell lung cancer 7899 495 WP:000000 query_1 TRUE 0.0270808 7 1342 5 0.0037258 0.7142857 WP:WP3953 WP mRNA, protein, and metabolite inducation pathway by cyclosporin A 7899 312 WP:000000 query_1 TRUE 0.0270808 7 1342 5 0.0037258 0.7142857 WP:WP134 WP Pentose phosphate metabolism 7899 281 WP:000000 query_1 TRUE 0.0288015 88 1342 26 0.0193741 0.2954545 WP:WP4263 WP Pancreatic adenocarcinoma pathway 7899 590 WP:000000 query_1 TRUE 0.0289016 13 1342 7 0.0052161 0.5384615 WP:WP4792 WP Purine metabolism 7899 71 WP:000000 query_1 TRUE 0.0289016 23 1342 10 0.0074516 0.4347826 WP:WP4197 WP Immune response to tuberculosis 7899 84 WP:000000 query_1 TRUE 0.0289016 13 1342 7 0.0052161 0.5384615 WP:WP4190 WP Mevalonate arm of cholesterol biosynthesis pathway 7899 44 WP:000000 query_1 TRUE 0.0289016 34 1342 13 0.0096870 0.3823529 WP:WP143 WP Fatty acid beta-oxidation 7899 567 WP:000000 query_1 TRUE 0.0289016 13 1342 7 0.0052161 0.5384615 WP:WP4236 WP Krebs cycle disorders 7899 614 WP:000000 query_1 TRUE 0.0289016 23 1342 10 0.0074516 0.4347826 WP:WP5046 WP NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence 7899 189 WP:000000 query_1 TRUE 0.0289016 84 1342 25 0.0186289 0.2976190 WP:WP4022 WP Pyrimidine metabolism 7899 638 WP:000000 query_1 TRUE 0.0302363 197 1342 49 0.0365127 0.2487310 WP:WP306 WP Focal adhesion 7899 16 WP:000000 query_1 TRUE 0.0330069 72 1342 22 0.0163934 0.3055556 WP:WP2572 WP Primary focal segmental glomerulosclerosis (FSGS) 7899 81 WP:000000 query_1 TRUE 0.0332650 20 1342 9 0.0067064 0.4500000 WP:WP4206 WP Hereditary leiomyomatosis and renal cell carcinoma pathway 7899 321 WP:000000 query_1 TRUE 0.0341695 68 1342 21 0.0156483 0.3088235 WP:WP3303 WP RAC1/PAK1/p38/MMP2 pathway 7899 519 WP:000000 query_1 TRUE 0.0348345 43 1342 15 0.0111773 0.3488372 WP:WP4753 WP Nucleotide excision repair 7899 562 WP:000000 query_1 TRUE 0.0373931 325 1342 74 0.0551416 0.2276923 WP:WP2059 WP Alzheimer’s disease and miRNA effects 7899 246 WP:000000 query_1 TRUE 0.0379103 17 1342 8 0.0059613 0.4705882 WP:WP368 WP Mitochondrial long chain fatty acid beta-oxidation 7899 87 WP:000000 query_1 TRUE 0.0417933 65 1342 20 0.0149031 0.3076923 WP:WP2374 WP Oncostatin M signaling pathway 7899 101 WP:000000 query_1 TRUE 0.0461687 8 1342 5 0.0037258 0.6250000 WP:WP4688 WP Serine metabolism 7899 150 WP:000000 query_1 TRUE 0.0461687 313 1342 71 0.0529061 0.2268371 WP:WP2882 WP Nuclear receptors meta-pathway 7899 365 WP:000000 query_1 TRUE 0.0461687 8 1342 5 0.0037258 0.6250000 WP:WP5211 WP Glucose metabolism in triple-negative breast cancer cells 7899 263 WP:000000 query_1 TRUE 0.0479701 273 1342 63 0.0469449 0.2307692 WP:WP4754 WP IL-18 signaling pathway 7899 361 WP:000000

x AAMDC AAMP AARS AASDHPPT ABCC3 ABCG1 ABCG2 ABHD12 ABHD17C ABHD3 ABRACL ACAA2 ACADVL ACAT1 ACAT2 ACLY ACOT7 ACP1 ACP5 ACP6 ACSL1 ACSL3 ACSL4 ACSL5 ACTB ACTG1 ACTL6A ACTN1 ACTN4 ACTR1A ACTR2 ACTR3 ADAM15 ADAM8 ADAM9 ADAR ADAT3,SCAMP4 ADD1 ADD3 ADGRF1 ADGRG1 ADI1 ADIPOR1 ADK ADORA2B ADRBK1 ADRM1 ADSL ADSS AES AFG3L2 AGPAT1 AGPAT2 AGR2 AGRN AHCY AHR AHRR,PDCD6 AHSA1 AIDA AIP AJUBA AK2 AK6,TAF9 AKAP1 AKIRIN1 AKR1A1 AKR1B1 AKR1B10 AKR1C3 AKT1 ALCAM ALDOA ALG3 ALG8 ALYREF AMD1 AMIGO2 AMZ2 ANAPC11 ANAPC13 ANAPC15 ANAPC16 ANAPC5 ANKRD1 ANKRD10 ANLN ANP32A ANP32B ANXA1 ANXA11 ANXA2 ANXA3 ANXA4 ANXA5 ANXA6 ANXA7 AP1G2 AP1M2 AP1S1 AP2B1 AP2M1 AP2S1 AP3S1 APEH APEX1 APH1A API5 APIP APLP2 APMAP APOA1BP APOE APP APRT ARAP1 ARCN1 ARF1 ARF3 ARF4 ARF5 ARF6 ARHGAP18 ARHGAP23 ARHGAP27 ARHGAP27 ARHGDIA ARHGDIB ARHGEF12 ARHGEF16 ARL2,SNX15 ARL4C ARL6IP1 ARL6IP4,OGFOD2 ARL6IP5 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4,ARPC4-TTLL3,TTLL3 ARPC5 ARPC5L ARPP19 ARRDC1 ASAH1 ASF1B ASNA1 ASNS ASPH ASS1 ATAD1 ATF4 ATF5 ATF6B ATF6B ATF6B ATF6B ATG3 ATIC ATOX1 ATP13A3 ATP1A1 ATP1A1-AS1 ATP1B1 ATP1B3 ATP2A2 ATP2C1 ATP5A1 ATP5B ATP5C1 ATP5D ATP5E,SLMO2 ATP5F1 ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J ATP5J2,ATP5J2-PTCD1,PTCD1 ATP5L ATP5O ATP6AP1 ATP6AP2 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0E1 ATP6V1A ATP6V1D ATP6V1E1 ATP6V1F ATP6V1G1 ATP6V1G2,DDX39B ATP6V1H ATPIF1 ATRAID ATXN2L AUP1 AURKA AURKAIP1 AZIN1 B2M B3GNT3 B4GALT1 B4GALT5 BABAM1 BAD BAG3 BAG6 BAG6 BAG6 BAG6 BAG6 BAG6 BAG6 BAIAP2L1 BANF1 BAX BCAP31 BCCIP BCL2L1 BCL2L2,BCL2L2-PABPN1,PABPN1 BCL7B BCL9L BCYRN1 BECN1 BHLHE41 BID BIRC2 BIRC5 BLOC1S1,RDH5 BLOC1S5,EEF1E1,TXNDC5 BLVRA BLVRB BNIP3 BOD1 BOLA3 BRI3 BRK1 BRMS1 BSCL2,HNRNPUL2 BSG BTF3 BUB3 BUD31 BYSL BZW1 BZW2 C11orf1 C11orf31 C11orf58 C11orf68 C11orf73 C12orf57 C14orf1 C14orf166 C14orf2 C15orf48 C17orf49,RNASEK C17orf89 C18orf32,RPL17,RPL17-C18orf32 C19orf33 C19orf43 C19orf48 C19orf53 C1orf122 C1orf43 C1QBP C20orf24,TGIF2,TGIF2-C20orf24 C21orf33 C4orf48 C5orf15 C5orf45 C6orf48 C6orf48 C6orf48 C6orf48 C6orf48 C6orf62 C7orf50 C7orf55,C7orf55-LUC7L2,LUC7L2 C8orf59 C9orf16 C9orf89 CAB39 CALB2 CALM1 CALM2 CALM3 CALR CALU CAND1 CANT1 CANX CAP1 CAPG CAPN1 CAPN2 CAPNS1 CAPRIN1 CAPZA1 CAPZA2 CAPZB CARD11 CARHSP1 CARM1 CARS CASC4 CASP4 CAST CAV1 CBR1 CBS CBX1 CBX3 CCDC142,MRPL53 CCDC47 CCDC85B CCM2 CCNB1 CCNB1IP1 CCNB2 CCNC CCND1 CCND3 CCNG1 CCNH CCNI CCT2 CCT3 CCT4 CCT5 CCT6A CCT7 CCT8 CD109 CD151 CD164 CD276 CD44 CD46 CD47 CD59 CD63 CD70 CD74 CD81 CD82 CD9 CDC123 CDC20 CDC26 CDC37 CDC42 CDC42EP3 CDC42EP4 CDC42SE2 CDCA4 CDCA5 CDCA7L CDH1 CDIPT CDK1 CDK16 CDK2AP1 CDK2AP2 CDK4 CDK5RAP3 CDK7 CDKN3 CDV3 CEBPB CENPK CEP55 CEP57 CERS2 CETN2 CFL1 CGGBP1 CHCHD1 CHCHD10 CHCHD2 CHCHD3 CHCHD5 CHCHD7 CHKA CHMP1A CHMP1B CHMP2A CHMP3,RNF103,RNF103-CHMP3 CHMP4B CHPF CHTF8 CHURC1,CHURC1-FNTB,FNTB CIB1 CIRBP CITED4 CKAP4 CKLF,CKLF-CMTM1,CMTM1 CKS1B CKS2 CLDN12 CLDN4 CLDN7 CLIC1 CLIC1 CLIC1 CLIC1 CLIC1 CLIC1 CLIC1 CLIC4 CLINT1 CLIP4 CLN6 CLNS1A CLPTM1 CLPTM1L CLSTN1 CLTA CLTC CLU CMC2 CMPK1 CMTM6 CMTM7 CNBP CNIH1 CNIH4 CNN2 CNN3 CNOT11 CNOT7 CNOT8 CNPY2,PAN2 CNPY3 COA1 COA3 COA4 COASY COL18A1 COL6A1 COLGALT1 COMMD4 COMMD7 COMT COMTD1 COPA COPB1 COPB2 COPE COPG1 COPRS COPS3 COPS5 COPS6 COPS8 COPZ1 COQ10B CORO1B CORO1C COTL1 COX11 COX14 COX16,SYNJ2BP,SYNJ2BP-COX16 COX17 COX4I1 COX5A COX5B COX6A1 COX6B1 COX6C COX7A2 COX7A2L COX7B COX7C COX8A CP CPD CPNE1,RBM12 CPNE3 CPSF1 CPT1A CPVL CREG1 CRIP1 CS CSDE1,NRAS CSE1L CSNK1A1 CSNK1D CSNK2B CSNK2B CSNK2B CSNK2B CSNK2B CSNK2B CSNK2B CSRP1 CST1 CST3 CST4 CSTB CTBP1 CTBP2 CTDNEP1 CTDSP2 CTHRC1 CTNNA1 CTNNAL1 CTNNB1 CTNND1,TMX2 CTPS1 CTSA CTSB CTSC CTSD CTSH CTSL CTSZ CTTN CUEDC1 CUTA CUTA CWC15 CX3CL1 CXCL5 CXCL8 CXXC5 CYB561 CYB5A CYB5B CYBA CYC1 CYCS CYP51A1 CYSTM1 DAD1 DAG1 DANCR DAP DAP3 DARS DAZAP1 DAZAP2 DBI DBNDD2,SYS1 DBNL DCAF7 DCBLD2 DCPS DCTD DCTN2 DCTN6 DCTPP1 DDB1 DDIT4 DDOST DDR1 DDR1 DDR1 DDR1 DDR1 DDR1 DDT DDX1 DDX17 DDX18 DDX21 DDX24 DDX39A DDX3X DDX42 DDX5 DDX6 DECR1 DEGS1 DEK DENR DERL1 DGAT1 DGUOK DHCR24 DHCR7 DHFR DHPS DHRS7 DHX15 DHX32 DHX9 DIAPH1 DKC1 DKK1 DLAT DLST DMKN DNAJA1 DNAJB1 DNAJB11 DNAJB6 DNAJC10 DNAJC25,DNAJC25-GNG10,GNG10 DNAJC4 DNAJC5 DNAJC7 DNAJC9 DNM2 DNPEP DNPH1 DNTTIP1 DPAGT1 DPH1,OVCA2 DPM1 DPP7 DPY30 DRAM1 DRAP1 DSG2 DSTN DTYMK DUSP4 DUSP5 DUSP6 DUT DYNLL1 DYNLL2 DYNLRB1 DYNLT1 EBNA1BP2 EBP EBPL ECH1 ECHS1 ECI1 ECT2 EDF1 EDIL3 EEF1A1 EEF1A2 EEF1B2 EEF1D EEF1G EEF2 EFHD2 EFTUD2 EGLN2,MIA,RAB4B EHD1 EHD4 EHF EI24 EIF1 EIF1AX EIF1AY EIF2A EIF2AK1 EIF2B2 EIF2S1 EIF2S2 EIF2S3 EIF3A EIF3B EIF3D EIF3E EIF3F EIF3G EIF3H EIF3I EIF3K EIF3L EIF3M EIF4A1,SENP3 EIF4A2 EIF4A3 EIF4B EIF4E2 EIF4EBP1 EIF4EBP2 EIF4G1 EIF4G2 EIF4H EIF5 EIF5A EIF6 ELF3 ELOF1 ELOVL1 ELOVL5 ELOVL6 EMC10 EMC3 EMC4 EMC7 EMD EML4 EMP1 EMP3 ENC1 ENDOD1 ENO1 ENOPH1 ENSA ENY2 EPAS1 EPB41L1 EPB41L4A-AS1 EPCAM EPHA2 EPN1 ERAP2 EREG ERGIC1 ERGIC3 ERH ERLEC1 ERLIN1 ERO1A ERP29 ERRFI1 ERV3-1,ZNF117 ESD ESRP1 ESRRA ETF1 ETFA ETFB ETS1 ETV4 EWSR1 EXOSC4 EZR F11R F2R F2RL1 FAAP20 FABP5 FADD FAM101A,ZNF664,ZNF664-FAM101A FAM102A FAM120A FAM127B FAM129B FAM162A FAM166A FAM168B FAM210B FAM213A FAM213B FAM32A FAM3C FAM49B FAM60A FAM83D FAM83H FAM89A FAM89B FAM96A FAM96B FASN FASTK FAU FBL FBXO22-AS1 FBXO7 FBXW5 FDFT1 FDPS FGD5-AS1 FH FHL2 FIBP FIS1 FKBP1A,SDCBP2 FKBP2 FKBP3 FKBP8 FLNA FLNB FLOT2 FOSL1 FOXP4 FOXQ1 FSCN1 FTH1 FTL FUBP1 FUCA1 FUCA2 FURIN FUS FUT8 FXYD3 FXYD5 G3BP1 G3BP2 G6PC3 G6PD GABARAP GABARAPL2 GADD45GIP1 GALE GALNT1 GALNT10 GALNT12 GALNT2 GALNT3 GANAB GAPDH GARS GART GAS5 GBAS GDE1 GDF15 GDI1 GDI2 GET4 GGCT GGH GHITM GINM1 GIPC1 GLB1,TMPPE GLO1 GLRX3 GLRX5 GLTSCR2 GLUD1 GLUL GMPR2 GMPS GNA12 GNAI2 GNAS GNB1 GNB2 GNB2L1 GNG5 GNL2 GNPDA1 GNS GOLM1 GOLPH3 GORASP2 GOT1 GOT2 GPAA1 GPC1 GPI GPR87 GPRC5A GPRC5B GPRC5C GPS1 GPX1 GPX2 GPX3 GPX4 GRB10 GRB2 GRHPR GRINA GRN GRPEL1 GSDMD GSN GSPT1 GSR GSTK1 GSTO1 GSTO2 GSTP1 GTF2I GTF3A GTPBP2 GUK1 GULP1 H1F0 H1FX H2AFV H2AFX H2AFY H2AFZ H3F3B HACD3 HADHA HADHB HAT1 HAX1 HDAC1 HDAC3 HDGF HDLBP HEBP2 HEXA HEXB HIATL1 HIF1A HIGD1A HIGD2A HINT1 HINT2 HIST1H2BK HLA-A HLA-A HLA-A HLA-A HLA-A HLA-A HLA-A HLA-A HLA-B HLA-B HLA-B HLA-B HLA-B HLA-B HLA-C HLA-C HLA-C HLA-C HLA-C HLA-C HLA-C HLA-DRA HLA-DRA HLA-DRA HLA-DRA HLA-DRA HLA-DRA HLA-DRA HLA-E HLA-E HLA-E HLA-E HLA-E HLA-E HLA-E HLA-F HLA-F HLA-F HLA-F HLA-F HLA-F HLA-H HLA-H HLA-H HLA-H HLA-H HLA-H HLA-H HLA-H HM13 HMGA1 HMGA2 HMGB1 HMGB2 HMGCR HMGCS1 HMGN1 HMGN2 HMGN3 HN1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH2,RPL36A,RPL36A-HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPU HNRNPUL1 HP1BP3 HPCAL1 HPRT1 HSBP1 HSD17B10 HSD17B11 HSD17B12 HSD17B4 HSP90AA1 HSP90AB1 HSP90B1 HSPA4 HSPA5 HSPA8 HSPA9 HSPB1 HSPB11 HSPH1 HTATIP2 HYOU1 HYPK,SERF2 IAH1 IARS IARS2 ID2 IDH1 IDH2 IDH3G IDI1 IDS IER2 IER3 IER3 IER3 IER3 IER3 IER3 IFI27 IFI27L2 IFI35 IFI44 IFI6 IFIT2 IFIT3 IFITM1 IFITM3 IFNGR1 IFNGR2 IGBP1 IGF2BP2 IGF2BP3 IGFBP4 IGFBP7 IK IL18 ILF2 ILF3 ILK IMMT IMP3 IMP4 IMPA2 IMPAD1 IMPDH1 IMPDH2 INF2 INO80B,WBP1 INPPL1 INSIG1 IPO7 IQGAP1 IRAK1 IRF2BP2 IRF9 ISG15 ITGA2 ITGA3 ITGA6 ITGAV ITGB1 ITGB2 ITGB4 ITGB5 ITM2B ITM2C ITPK1 JKAMP JTB JUN JUNB JUND JUP KARS KCNS3 KCTD14,NDUFC2,NDUFC2-KCTD14 KDELC2 KDELR1 KDELR2 KDM1A KHDRBS1 KHSRP KIAA0100 KIAA0101 KIAA0226 KIAA1191 KIAA1279 KIAA1522 KIF22 KIF5B KLC1 KLF5 KLHDC3 KLHL5 KPNA2 KPNB1 KRAS KRT19 KRT7 KRT80 KRTCAP2 KTN1 KXD1 KYNU LAMA3 LAMA5 LAMB1 LAMB3 LAMC2 LAMP1 LAMP2 LAMTOR1 LAMTOR2 LAMTOR4 LAMTOR5 LAP3 LAPTM4A LAPTM4B LAPTM5 LARP1 LASP1 LCN2 LCP1 LDHA LDHB LDLR LFNG LGALS1 LGALS3 LGALS3BP LGMN LIMK1 LINC00152 LINC00493 LINC00657 LINC00673 LINC00998 LINC01137 LINC01420 LINC01578 LIPA LIPG LIPH LITAF LLPH LMAN1 LMAN2 LMNA LMNB1 LMNB2 LMO7 LOC100129148 LOC284454,MIR24-2 LPCAT1 LPCAT3 LRP10 LRP11 LRP5 LRPPRC LRRC20 LRRC59 LRRC75A-AS1,SNORD49B LRRC8A LSM12 LSM14A LSM2 LSM2 LSM2 LSM2 LSM2 LSM2 LSM3 LSM4 LSM5 LSM7 LSR LSS LTA4H LTB LTB LTB LTB LTB LTB LTB LTB LTBP3 LTBR LUZP6 LY6D LY6E LYPD1 LYPLA1 M6PR MAD2L1 MAD2L1BP MAEA MAF1 MAGED1 MAGED2 MAGOH MAGT1 MAL2 MALL MALSU1 MANBAL MANF MAP2K2 MAP3K11 MAP4K4 MAP7D1 MAPK1 MAPRE1 MARCKSL1 MARS MAT2A MAT2B MATR3 MAX MAZ MBNL1 MBP MCCC2 MCL1 MCM2 MCM3 MCM4 MCM6 MCM7 MCMBP MDFI MDH1 MDH2 MDK MDP1,NEDD8,NEDD8-MDP1 MEA1 MEAF6 MED10 MED20 MET METAP2 METTL23 METTL5 METTL9 MFF MFGE8 MFSD10 MGAT1 MGAT4B MGMT MGST1 MGST2 MGST3 MID1IP1 MIEN1 MIF MILR1 MIR1260B MIR1282 MIR196A1 MIR25 MIR3064 MIR3661 MIR3918 MIR4461 MIR4664 MIR4737 MIR5047 MIR614 MIR6732 MIR6891 MIR6891 MIR6891 MIR6891 MIR6891 MIR6891 MIR6891 MIR6891 MIR6891 MIR6891 MIR7161 MIR762 MKRN1 MLEC MLF2 MMADHC MMP7 MOB1A MORF4L1 MORF4L2 MPC1 MPST MRFAP1 MRFAP1L1 MRPL10 MRPL11 MRPL12 MRPL13 MRPL14 MRPL15 MRPL18 MRPL2 MRPL20 MRPL21 MRPL23 MRPL24 MRPL27 MRPL3 MRPL32 MRPL33 MRPL34 MRPL36 MRPL37 MRPL40 MRPL41 MRPL43 MRPL45 MRPL47 MRPL48 MRPL49 MRPL51 MRPL52 MRPL55 MRPS10 MRPS12 MRPS15 MRPS16 MRPS17 MRPS18A MRPS2 MRPS21 MRPS22 MRPS23 MRPS24,URGCP,URGCP-MRPS24 MRPS28 MRPS33 MRPS34 MRPS35 MRPS36 MRPS6,SLC5A3 MRPS7 MSMO1 MSN MT1E MT1L MT2A MTCH1 MTCH2 MTDH MTHFD1 MTHFD2 MTRNR2L1 MTRNR2L2 MTRNR2L8 MTX2 MVP,PAGR1 MX1 MXD3 MYC MYDGF MYEOV MYEOV2 MYH9 MYL12A MYL12B MYL6 MYO19 MYOF MZT2A MZT2B NAA10 NAA20 NAA50 NACA NADSYN1 NANS NAP1L1 NAP1L4 NARR,RAB34 NARS NASP NBR1 NCBP2 NCK2 NCKAP1 NCL NCOA4 NCSTN NDC80 NDFIP1 NDRG1 NDUFA1 NDUFA11 NDUFA12 NDUFA13 NDUFA2 NDUFA3 NDUFA4 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFAF2 NDUFAF3 NDUFB1 NDUFB10 NDUFB11 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFS1 NDUFS2 NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 NELFCD NELFE NELFE NELFE NELFE NELFE NELFE NET1 NETO2 NEU1 NEU1 NEU1 NEU1 NEU1 NEU1 NEU1 NEU1 NFE2L1 NFE2L2 NFE2L3 NFKBIA NFU1 NFYC NGFRAP1 NGRN NHP2 NHP2L1 NIPA2 NIT2 NME1,NME1-NME2,NME2 NME3 NOC2L NOL11 NOL7 NOLC1 NONO NOP10 NOP56 NOP58 NPC2 NPEPL1,STX16 NPLOC4 NPM1 NPM3 NPTN NQO1 NR2F6 NSA2 NSUN2 NT5C2 NT5C3A NT5DC2 NT5E NUBP2 NUCKS1 NUDC NUDCD2 NUDT22 NUDT3,RPS10,RPS10-NUDT3 NUDT4 NUMA1 NUP37 NUSAP1 NUTF2 OARD1 OAS1 OAT OAZ1 OAZ2 OCIAD1 OCIAD2 ODC1 OGDH OGT OLA1 ORAI1 ORMDL2 OS9 OST4 OSTC OSTF1 OTUB1 OXA1L P2RX5,TAX1BP3 P4HB PA2G4 PABPC1 PABPC4 PACSIN2 PAF1 PAFAH1B2 PAICS PAIP1 PAIP2 PAK1 PAK4 PAM PANK4 PAPOLA PARK7 PARL PARP1 PARP14 PARP4 PARP9 PATL1 PCBD1 PCBP1 PCBP2 PCDH1 PCDHGA1,PCDHGA10,PCDHGA11,PCDHGA12,PCDHGA2,PCDHGA3,PCDHGA4,PCDHGA5,PCDHGA6,PCDHGA7,PCDHGA8,PCDHGA9,PCDHGB1,PCDHGB2,PCDHGB3,PCDHGB4,PCDHGB5,PCDHGB6,PCDHGB7,PCDHGC3,PCDHGC4,PCDHGC5 PCGF5 PCK2 PCMT1 PCNA PCNA-AS1 PCNP PDAP1 PDCD10 PDCD5 PDHB PDIA3 PDIA4 PDIA6 PDLIM1 PDLIM7 PDP1 PDZD11 PEA15 PEBP1 PEG10 PEPD PERP PET100 PEX10 PFDN1 PFDN2 PFDN5 PFDN6 PFDN6 PFDN6 PFDN6 PFDN6 PFKL PFKP PFN1 PFN2 PGAM1 PGD PGK1 PGLS PGRMC1 PHB PHB2 PHC2 PHF19 PHF5A PHGDH PHLDA1 PHLDA2 PICALM PIGF PIGP PIGT PIH1D1 PIM3 PIP4K2C PKIB PKM PKN1 PKP3 PLA2G16 PLAA PLAU PLCH2 PLD3 PLEC PLEK2 PLEKHB1 PLEKHB2 PLEKHJ1 PLIN2 PLK1 PLK2 PLP2 PLS1 PLS3 PLSCR1 PLSCR3,TMEM256 PLXNA1 PLXNB2 PMAIP1 PNKD POLD2 POLD4 POLDIP2 POLE3 POLE4 POLR1C POLR1D POLR2B POLR2G POLR2H POLR2I POLR2K POLR2L POMP PON2 PON3 POP7 POR PP7080 PPA1 PPA2 PPAP2C PPARG PPDPF PPIA PPIB PPIC PPIF PPM1G PPME1 PPP1CA PPP1CB PPP1CC PPP1R14B PPP1R35 PPP1R7 PPP2CA PPP2R1A PPP2R4 PPP2R5C PPP3R1 PPP4C PPP6R3 PPT1 PQBP1 PRC1 PRCP PRDX1 PRDX2 PRDX3 PRDX4 PRDX5 PRDX6 PRELID1 PRKAG1 PRKAR1A PRKCSH PRKRIR PRMT1 PRMT2 PRMT5 PRNP PRPF19 PRPF6 PRR13 PRR15 PRRC2A PRRC2A PRRC2A PRRC2A PRRC2A PRRC2A PRRC2A PRSS22 PRSS23 PRSS8 PSAP PSAT1 PSENEN PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB8 PSMB8 PSMB8 PSMB8 PSMB8 PSMB8 PSMB8 PSMB9 PSMB9 PSMB9 PSMB9 PSMB9 PSMB9 PSMB9 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSME1 PSME2 PSME3 PSMG1 PSMG2 PSMG3 PTBP1 PTBP3 PTDSS1 PTGES2 PTGES3 PTK2 PTMA PTOV1 PTP4A2 PTPN1 PTPN12 PTPRJ PTRH2 PTRHD1 PTS PTTG1 PTTG1IP PUF60 PXN PYCARD PYCR2 PYGB PYURF QARS QSOX1 RAB10 RAB11A RAB11B RAB12 RAB13 RAB14 RAB1A RAB1B RAB25 RAB2A RAB5C RAB6A RAB7A RAB8A RABAC1 RABGGTB RAC1 RAC2 RACGAP1 RAD21 RAD23A RAD23B RAE1 RALB RALBP1 RALY RAN RANBP1 RAP1B RARRES3 RARS RASSF3 RBBP7 RBM14,RBM14-RBM4,RBM4 RBM3 RBM39 RBM42 RBMX RBP1 RBP4 RBX1 RCC2 RCN1 RCN2 RDH10 RDH11 RDX REEP3 REEP5 RELA REPIN1 RER1 REXO2 RFC2 RFC4 RGS2 RHBDD2 RHEB RHOA RHOBTB3 RHOC RHOD RHOF RNASE1 RNASEH2A RNASET2 RNF13 RNF145 RNF149 RNF181 RNF26 RNF4 RNF5 RNF5 RNF5 RNF5 RNF5 RNF5 RNF5 RNF7 RNH1 RNPEPL1 RNPS1 ROMO1 RPA3 RPL10 RPL10A RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL4 RPL41 RPL5 RPL6 RPL7 RPL7A RPL7L1 RPL8 RPL9 RPLP0 RPLP1 RPLP2 RPN1 RPN2 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS18 RPS18 RPS18 RPS18 RPS18 RPS18 RPS19 RPS19BP1 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS6KA4 RPS6KB2 RPS7 RPS8 RPS9 RPSA RRAGA RRM1 RRM2 RRP36 RSL24D1 RTCB RTEL1,TNFRSF6B RTFDC1 RTN3 RTN4 RUVBL1 RUVBL2 RYK S100A10 S100A11 S100A13 S100A16 S100A2 S100A4 S100A6 S100P SAC3D1 SAE1 SAP18 SAR1A SARAF SARNP SARS SAT1 SAYSD1 SBDS SCAMP2 SCAMP3 SCAND1 SCARB2 SCD SCFD1 SCNN1A SCOC SCP2 SCRN1 SCYL1 SDC1 SDC4 SDCBP SDF2 SDF4 SDHA SDHB SDHC SDHD SDR39U1 SEC11A SEC13 SEC14L1 SEC24C SEC61A1 SEC61B SEC61G SEH1L SEL1L3 SELT SEMA3A SEMA4B SEPHS2 SEPW1 SERINC1 SERINC2 SERINC3 SERP1 SERPINA1 SERPINA3 SERPINA5 SERPINH1 SET SETD3 SF1 SF3A3 SF3B1 SF3B2 SF3B4 SF3B5 SF3B6 SFN SFPQ SFT2D1 SFXN4 SGCE SGPL1 SH2B3 SH3BGRL3 SH3BP4 SH3GLB2 SH3KBP1 SH3YL1 SHC1 SHFM1 SHISA5 SHMT2 SIGMAR1 SIVA1 SKA2 SKI SKP1 SLBP SLC12A2 SLC12A7 SLC16A3 SLC1A5 SLC20A1 SLC22A20 SLC25A1 SLC25A3 SLC25A39 SLC25A5 SLC2A1 SLC30A9 SLC35A2 SLC35B1 SLC35B2 SLC35F2 SLC37A2 SLC37A3 SLC37A4 SLC38A1 SLC38A10 SLC38A2 SLC39A1 SLC39A4 SLC39A7 SLC39A7 SLC39A7 SLC39A7 SLC39A7 SLC39A7 SLC39A9 SLC3A2 SLC44A2 SLC4A2 SLC50A1 SLC52A2 SLC7A5 SLC9A3R1 SLC9A3R2 SLCO4A1 SLIRP SMAD3 SMAD6 SMAP2 SMARCD2 SMARCE1 SMC3 SMC4 SMCO4 SMIM14 SMIM15 SMIM7 SMOC1 SMS SND1 SNF8 SNHG15 SNHG16 SNHG25 SNHG5 SNHG6 SNHG7,SNORA17,SNORA43 SNHG8 SNORA1 SNORA10 SNORA18 SNORA32 SNORA40 SNORA61 SNORA63 SNORA70 SNORA8 SNORD104 SNORD16 SNORD22 SNORD28 SNORD29 SNORD35B SNORD36A SNORD47 SNORD4A SNORD58C SNORD76 SNORD80 SNORD83A SNRNP200 SNRNP70 SNRPA SNRPA1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPE SNRPF SNRPG SNW1 SNX12 SNX17 SNX3 SNX5 SNX6 SNX9 SOD1 SOD2 SON SORL1 SOX2 SOX9 SP100 SPATA20 SPATS2L SPCS1 SPG21 SPINT1 SPINT2 SPP1 SPRY2 SPTBN1 SPTLC1 SQLE SQRDL SQSTM1 SREBF1 SREBF2 SRF SRI SRP14 SRP54 SRP68 SRP9 SRPR SRSF1 SRSF2 SRSF3 SRSF5 SRSF6 SRSF7 SRSF9 SSB SSBP1 SSFA2 SSNA1 SSR2 SSR3 SSR4 SSRP1 SSSCA1 SSU72 ST13 ST14 ST3GAL4 STARD10 STARD3NL STARD7 STAT1 STAT3 STAT6 STAU1 STC2 STEAP1 STIM1 STIP1 STK24 STK39 STMN1 STOM STOML2 STRA13 STRAP STS STT3A STT3B STYXL1 SUB1 SUCLG1 SULF2 SUMF2 SUMO1 SUMO2 SUMO3 SUN1 SUPT16H SUPT4H1 SUPT5H SURF4 SYNCRIP SYNGR2 SYPL1 SYVN1 TACSTD2 TAF10 TAF15 TAF1D TAF7 TAGLN2 TALDO1 TANK TAPBP,ZBTB22 TARDBP TARS TAX1BP1 TBCA TBCB TBCC TBRG4 TCEA1 TCEAL8 TCEB1 TCEB2 TCF7L2 TCIRG1 TCN1 TCP1 TECR TES TESC TFDP1 TFF1 TFF2 TFF3 TFG TFPI TFRC TGFA TGFBI TGFBR2 TGIF1 TGM2 TGOLN2 THAP4 THOC7 THYN1 TIAL1 TICAM2,TMED7,TMED7-TICAM2 TIMM17B TIMM23 TIMM8B TIMM9 TIMMDC1 TIMP1 TIMP2 TIMP3 TINAGL1 TJAP1 TJP2 TK1 TKT TLCD1 TM4SF1 TM7SF2,VPS51 TM7SF3 TM9SF1 TM9SF2 TM9SF3 TMA7 TMBIM1 TMBIM4 TMBIM6 TMC6 TMED10 TMED2 TMED3 TMED4 TMED9 TMEM106C TMEM123 TMEM126A TMEM126B TMEM141 TMEM147 TMEM14A TMEM14B TMEM14C TMEM156 TMEM165 TMEM189,TMEM189-UBE2V1,UBE2V1 TMEM205 TMEM219 TMEM230 TMEM248 TMEM258 TMEM259 TMEM30A TMEM30B TMEM45B TMEM50A TMEM55B TMEM59 TMEM60 TMEM63A TMEM97 TMEM9B TMPO TMPRSS3 TMPRSS4 TMSB10 TMSB4X TMUB1 TNFAIP2 TNFRSF10B TNFRSF12A TNFRSF14 TNFRSF21 TNFSF9 TNIP1 TNPO1 TNS3 TNS4 TOB1 TOMM20 TOMM22 TOMM40 TOMM5 TOMM6 TOMM7 TOMM70A TOP1 TOP2A TOR1A TP53 TPBG TPD52L2 TPI1 TPM1 TPM3 TPM4 TPRA1 TPT1 TPX2 TRA2B TRAF4 TRAM1 TRAP1 TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC5 TRIB3 TRIM25 TRIM28 TRIM8 TRIP12 TRIP13 TRMT112 TRPC4AP TRPT1 TSG101 TSKU TSN TSPAN1 TSPAN13 TSPAN14 TSPAN15 TSPAN3 TSPO TST TSTA3 TSTD1 TTYH3 TUBA1B TUBA1C TUBA4A TUBB TUBB TUBB TUBB TUBB TUBB TUBB TUBB TUBB4B TUBB6 TUBG1 TUBGCP2 TUFM TUSC3 TWF1 TWSG1 TXN TXNIP TXNL4A TXNRD1 TYMS U2AF1 U2AF2 UBA1 UBA2 UBA52 UBALD2 UBAP2L UBB UBC UBD UBD UBD UBD UBD UBD UBD UBE2A UBE2C UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2H UBE2L3 UBE2L6 UBE2M UBE2N UBE2S UBE2T UBE2V2 UBE2Z UBE3C UBL5 UBQLN1 UBXN4 UCHL3 UCK2 UCP2 UFC1 UFD1L UGCG UGDH UGP2 UNC50 UNC93B1 UNG UPP1 UQCR10 UQCR11 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH UQCRQ URI1 UROS USF2 USMG5 USP14 USP22 USP39 UTP18 UXS1 UXT VAMP3 VAMP5 VAMP8 VAPA VAT1 VBP1 VCL VCP VDAC1 VDAC2 VDAC3 VEGFA VIMP VKORC1 VMP1 VOPP1 VPS25 VPS26A VPS28 VPS29 VPS35 VPS37B VRK1 VTI1B WAC-AS1 WARS WBP2 WBP5 WBSCR22 WDR1 WDR34 WDR45B WDR61 WDR83OS WFDC2 WFS1 WSB2 WTAP WWTR1 XBP1 XPNPEP1 XPO1 XPO5 XPOT XRCC5 XRCC6 YAP1 YBX1 YBX3 YDJC YES1 YIF1A YIPF2 YIPF3 YIPF4 YKT6 YME1L1 YPEL5 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ YY1 ZC3H12A ZC3H15 ZC3HAV1 ZDHHC12 ZDHHC16 ZDHHC20 ZDHHC24 ZDHHC4 ZDHHC7 ZFAND1 ZFAND6 ZFAS1 ZFP36L1 ZFPL1 ZFYVE21 ZMAT2 ZNF146 ZNF207 ZNF511 ZNHIT1 ZNHIT3 ZPR1 ZWINT ZYX x hsapiens x FALSE x FALSE x TRUE x GO:BP REAC WP x FALSE x ENTREZGENE_ACC x annotated x FALSE x fdr x 0.05 x TRUE x 21128 x 27960 x 10777 x 2611 x 7899 x 767 x AARS ADAT3,SCAMP4 AES AHRR,PDCD6 AK6,TAF9 APOA1BP ARL2,SNX15 ARL6IP4,OGFOD2 ARPC4,ARPC4-TTLL3,TTLL3 ASNA1 ATP5A1 ATP5B ATP5C1 ATP5D ATP5E,SLMO2 ATP5F1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J2,ATP5J2-PTCD1,PTCD1 ATP5L ATP5O ATP6V1G2,DDX39B ATPIF1 BCL2L2,BCL2L2-PABPN1,PABPN1 BLOC1S1,RDH5 BLOC1S5,EEF1E1,TXNDC5 BSCL2,HNRNPUL2 C11orf31 C11orf73 C17orf49,RNASEK C17orf89 C18orf32,RPL17,RPL17-C18orf32 C19orf43 C20orf24,TGIF2,TGIF2-C20orf24 C21orf33 C5orf45 C6orf48 C7orf55,C7orf55-LUC7L2,LUC7L2 C8orf59 C9orf16 CCDC142,MRPL53 CHMP3,RNF103,RNF103-CHMP3 CHURC1,CHURC1-FNTB,FNTB CKLF,CKLF-CMTM1,CMTM1 CNPY2,PAN2 COX16,SYNJ2BP,SYNJ2BP-COX16 CPNE1,RBM12 CSDE1,NRAS CTNND1,TMX2 DARS DBNDD2,SYS1 DNAJC25,DNAJC25-GNG10,GNG10 DPH1,OVCA2 EGLN2,MIA,RAB4B EIF4A1,SENP3 ERV3-1,ZNF117 FAM101A,ZNF664,ZNF664-FAM101A FAM127B FAM129B FAM213A FAM213B FAM60A FAM96A FAM96B FBXO22-AS1 FKBP1A,SDCBP2 GARS GBAS GLB1,TMPPE GLTSCR2 GNB2L1 H1F0 H1FX H2AFV H2AFX H2AFY H2AFZ H3F3B HIATL1 HN1 HNRNPH2,RPL36A,RPL36A-HNRNPH2 HYPK,SERF2 IARS INO80B,WBP1 KARS KCTD14,NDUFC2,NDUFC2-KCTD14 KIAA0101 KIAA0226 KIAA1279 LINC00152 LINC00493 LINC00657 LINC00998 LINC01137 LINC01420 LINC01578 LOC100129148 LOC284454,MIR24-2 LRRC75A-AS1,SNORD49B LUZP6 MARS MDP1,NEDD8,NEDD8-MDP1 MIR4461 MRPS24,URGCP,URGCP-MRPS24 MRPS6,SLC5A3 MTRNR2L1 MTRNR2L2 MTRNR2L8 MVP,PAGR1 MYEOV2 NARR,RAB34 NARS NGFRAP1 NME1,NME1-NME2,NME2 NPEPL1,STX16 NUDT3,RPS10,RPS10-NUDT3 P2RX5,TAX1BP3 PCDHGA1,PCDHGA10,PCDHGA11,PCDHGA12,PCDHGA2,PCDHGA3,PCDHGA4,PCDHGA5,PCDHGA6,PCDHGA7,PCDHGA8,PCDHGA9,PCDHGB1,PCDHGB2,PCDHGB3,PCDHGB4,PCDHGB5,PCDHGB6,PCDHGB7,PCDHGC3,PCDHGC4,PCDHGC5 PCNA-AS1 PLA2G16 PLSCR3,TMEM256 PPAP2C PPP2R4 PRKRIR QARS RARRES3 RARS RBM14,RBM14-RBM4,RBM4 RTEL1,TNFRSF6B RTFDC1 SARS SELT SEPW1 SLC22A20 SNHG7,SNORA17,SNORA43 SNORD47 SNORD76 SNORD80 SQRDL SRPR SSFA2 SSSCA1 STRA13 TAPBP,ZBTB22 TARS TCEB2 TICAM2,TMED7,TMED7-TICAM2 TM7SF2,VPS51 TMEM189,TMEM189-UBE2V1,UBE2V1 TMEM55B TOMM70A TSTA3 UFD1L USMG5 VIMP WBP5 WBSCR22 WDR34 gene_id description number_of_go_annotations ENSG00000105393 BRISC and BRCA1 A complex member 1 [Source:HGNC Symbol;Acc:HGNC:25008] 137 ENSG00000269307 novel transcript 0 gene_id description number_of_go_annotations ENSG00000198668 calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442] 385 ENSG00000160014 calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449] 474 gene_id description number_of_go_annotations ENSG00000198668 calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442] 385 ENSG00000143933 calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445] 353 ENSG00000160014 calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449] 474 gene_id description number_of_go_annotations ENSG00000085063 CD59 molecule (CD59 blood group) [Source:HGNC Symbol;Acc:HGNC:1689] 106 ENSG00000284969 novel protein 35 gene_id description number_of_go_annotations ENSG00000070831 cell division cycle 42 [Source:HGNC Symbol;Acc:HGNC:1736] 587 ENSG00000289694 novel protein 65 gene_id description number_of_go_annotations ENSG00000286140 DERPC proline and glycine rich nuclear protein [Source:HGNC Symbol;Acc:HGNC:54084] 20 ENSG00000168802 chromosome transmission fidelity factor 8 [Source:HGNC Symbol;Acc:HGNC:24353] 118 gene_id description number_of_go_annotations ENSG00000263020 novel protein 31 ENSG00000204435 casein kinase 2 beta [Source:HGNC Symbol;Acc:HGNC:2460] 217 gene_id description number_of_go_annotations ENSG00000010404 iduronate 2-sulfatase [Source:HGNC Symbol;Acc:HGNC:5389] 63 ENSG00000241489 novel protein 5 gene_id description number_of_go_annotations ENSG00000015479 matrin 3 [Source:HGNC Symbol;Acc:HGNC:6912] 101 ENSG00000280987 matrin 3 [Source:NCBI gene (formerly Entrezgene);Acc:9782] 19 gene_id description number_of_go_annotations ENSG00000124641 mediator complex subunit 20 [Source:HGNC Symbol;Acc:HGNC:16840] 130 ENSG00000288721 novel protein 62 gene_id description number_of_go_annotations ENSG00000152082 mitotic spindle organizing protein 2B [Source:HGNC Symbol;Acc:HGNC:25886] 28 ENSG00000173272 mitotic spindle organizing protein 2A [Source:HGNC Symbol;Acc:HGNC:33187] 28 gene_id description number_of_go_annotations ENSG00000255339 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa (NDUFB8) and SEC31 homolog B (S. cerevisiae) (SEC31B) readthrough 46 ENSG00000166136 NADH:ubiquinone oxidoreductase subunit B8 [Source:HGNC Symbol;Acc:HGNC:7703] 130 gene_id description number_of_go_annotations ENSG00000256646 novel PSMA2 and C7orf25 readthrough 40 ENSG00000106588 proteasome 20S subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:9531] 81 gene_id description number_of_go_annotations ENSG00000129538 ribonuclease A family member 1, pancreatic [Source:HGNC Symbol;Acc:HGNC:10044] 60 ENSG00000136238 Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801] 468 gene_id description number_of_go_annotations ENSG00000214046 small integral membrane protein 7 [Source:HGNC Symbol;Acc:HGNC:28419] 3 ENSG00000268790 novel protein 3 gene_id description number_of_go_annotations ENSG00000201229 small nucleolar RNA, H/ACA box 63D [Source:HGNC Symbol;Acc:HGNC:52211] 0 ENSG00000200418 small nucleolar RNA, H/ACA box 63B [Source:HGNC Symbol;Acc:HGNC:52209] 32 ENSG00000199633 Small nucleolar RNA SNORA63 [Source:RFAM;Acc:RF00092] 0 ENSG00000202449 Small nucleolar RNA SNORA63 [Source:RFAM;Acc:RF00092] 0 ENSG00000200320 small nucleolar RNA, H/ACA box 63 [Source:HGNC Symbol;Acc:HGNC:10106] 32 ENSG00000199363 small nucleolar RNA, H/ACA box 63E [Source:HGNC Symbol;Acc:HGNC:52212] 32 ENSG00000252448 Small nucleolar RNA SNORA63 [Source:RFAM;Acc:RF00092] 0 ENSG00000199473 Small nucleolar RNA SNORA63 [Source:RFAM;Acc:RF00092] 0 ENSG00000201448 small nucleolar RNA, H/ACA box 63C [Source:HGNC Symbol;Acc:HGNC:52210] 32 ENSG00000201791 Small nucleolar RNA SNORA63 [Source:RFAM;Acc:RF00092] 0 ENSG00000199552 Small nucleolar RNA SNORA63 [Source:RFAM;Acc:RF00092] 32 gene_id description number_of_go_annotations ENSG00000253027 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000251796 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000252133 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000202379 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000206886 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000252724 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000207268 small nucleolar RNA, H/ACA box 70C [Source:HGNC Symbol;Acc:HGNC:33619] 32 ENSG00000206937 small nucleolar RNA, H/ACA box 70B [Source:HGNC Symbol;Acc:HGNC:33618] 32 ENSG00000206650 small nucleolar RNA, H/ACA box 70G [Source:HGNC Symbol;Acc:HGNC:34359] 32 ENSG00000206909 small nucleolar RNA, H/ACA box 70J [Source:HGNC Symbol;Acc:HGNC:52216] 32 ENSG00000252014 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000263666 small nucleolar RNA, H/ACA box 70D [Source:HGNC Symbol;Acc:HGNC:34356] 32 ENSG00000201376 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000200237 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000207098 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000252505 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000207244 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000252526 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000252969 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000201945 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000278010 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000206958 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000207274 small nucleolar RNA, H/ACA box 70I [Source:HGNC Symbol;Acc:HGNC:52215] 32 ENSG00000251925 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000252657 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000252199 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000276094 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000206637 small nucleolar RNA, H/ACA box 70H [Source:HGNC Symbol;Acc:HGNC:52214] 32 ENSG00000207165 small nucleolar RNA, H/ACA box 70 [Source:HGNC Symbol;Acc:HGNC:10231] 32 ENSG00000206869 small nucleolar RNA, H/ACA box 70F [Source:HGNC Symbol;Acc:HGNC:34358] 32 ENSG00000206661 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000207221 small nucleolar RNA, H/ACA box 70E [Source:HGNC Symbol;Acc:HGNC:34357] 32 ENSG00000253042 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000252258 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000202389 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 ENSG00000251893 Small nucleolar RNA SNORA70 [Source:RFAM;Acc:RF00156] 32 gene_id description number_of_go_annotations ENSG00000277194 small nucleolar RNA, C/D box 22 [Source:HGNC Symbol;Acc:HGNC:10145] 32 ENSG00000278527 Small nucleolar RNA SNORD22 [Source:RFAM;Acc:RF00099] 32 gene_id description number_of_go_annotations ENSG00000252284 small nucleolar RNA, H/ACA box 108 [Source:HGNC Symbol;Acc:HGNC:51401] 0 ENSG00000274544 small nucleolar RNA, C/D box 28 [Source:HGNC Symbol;Acc:HGNC:10150] 32 ENSG00000212295 small nucleolar RNA, C/D box 28B [Source:HGNC Symbol;Acc:HGNC:52225] 32 gene_id description number_of_go_annotations ENSG00000266086 novel transcript 0 ENSG00000136450 serine and arginine rich splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:10780] 94 gene_id description number_of_go_annotations ENSG00000271793 novel protein, SYNCRIP-SNX14 readthrough 9 ENSG00000135316 synaptotagmin binding cytoplasmic RNA interacting protein [Source:HGNC Symbol;Acc:HGNC:16918] 196 x ARHGAP27 ATF6B BAG6 CALM2 CALM3 CLIC1 CSNK2B CUTA DDR1 HLA-A HLA-B HLA-C HLA-DRA HLA-E HLA-F HLA-H IER3 LSM2 LTB MIR6891 MZT2B NELFE NEU1 PFDN6 PRRC2A PSMB8 PSMB9 RNASE1 RNF5 RPS18 SLC39A7 TUBB UBD x ENSG00000087884 x ENSG00000127837 x ENSG00000149313 x ENSG00000108846 x ENSG00000160179 x ENSG00000118777 x ENSG00000100997 x ENSG00000136379 x ENSG00000158201 x ENSG00000146386 x ENSG00000167315 x ENSG00000072778 x ENSG00000075239 x ENSG00000120437 x ENSG00000131473 x ENSG00000097021 x ENSG00000143727 x ENSG00000102575 x ENSG00000162836 x ENSG00000151726 x ENSG00000123983 x ENSG00000068366 x ENSG00000197142 x ENSG00000075624 x ENSG00000184009 x ENSG00000136518 x ENSG00000072110 x ENSG00000130402 x ENSG00000138107 x ENSG00000138071 x ENSG00000115091 x ENSG00000143537 x ENSG00000151651 x ENSG00000168615 x ENSG00000160710 x ENSG00000087274 x ENSG00000148700 x ENSG00000153292 x ENSG00000205336 x ENSG00000182551 x ENSG00000159346 x ENSG00000156110 x ENSG00000170425 x ENSG00000173020 x ENSG00000130706 x ENSG00000239900 x ENSG00000035687 x ENSG00000141385 x ENSG00000204310 x ENSG00000169692 x ENSG00000106541 x ENSG00000188157 x ENSG00000101444 x ENSG00000106546 x ENSG00000100591 x ENSG00000186063 x ENSG00000110711 x ENSG00000129474 x ENSG00000004455 x ENSG00000121057 x ENSG00000174574 x ENSG00000117448 x ENSG00000085662 x ENSG00000198074 x ENSG00000196139 x ENSG00000142208 x ENSG00000170017 x ENSG00000149925 x ENSG00000214160 x ENSG00000159063 x ENSG00000183684 x ENSG00000123505 x ENSG00000139211 x ENSG00000196704 x ENSG00000141552 x ENSG00000129055 x ENSG00000110200 x ENSG00000166295 x ENSG00000089053 x ENSG00000148677 x ENSG00000088448 x ENSG00000011426 x ENSG00000140350 x ENSG00000136938 x ENSG00000135046 x ENSG00000122359 x ENSG00000182718 x ENSG00000138772 x ENSG00000196975 x ENSG00000164111 x ENSG00000197043 x ENSG00000138279 x ENSG00000213983 x ENSG00000129354 x ENSG00000106367 x ENSG00000006125 x ENSG00000161203 x ENSG00000042753 x ENSG00000177879 x ENSG00000164062 x ENSG00000100823 x ENSG00000117362 x ENSG00000166181 x ENSG00000149089 x ENSG00000084234 x ENSG00000101474 x ENSG00000130203 x ENSG00000142192 x ENSG00000198931 x ENSG00000186635 x ENSG00000095139 x ENSG00000143761 x ENSG00000134287 x ENSG00000168374 x ENSG00000004059 x ENSG00000165527 x ENSG00000146376 x ENSG00000275832 x ENSG00000159314 x ENSG00000141522 x ENSG00000111348 x ENSG00000196914 x ENSG00000130762 x ENSG00000188042 x ENSG00000170540 x ENSG00000144746 x ENSG00000241685 x ENSG00000130429 x ENSG00000163466 x ENSG00000111229 x ENSG00000162704 x ENSG00000136950 x ENSG00000128989 x ENSG00000197070 x ENSG00000104763 x ENSG00000105011 x ENSG00000070669 x ENSG00000198363 x ENSG00000130707 x ENSG00000138138 x ENSG00000128272 x ENSG00000169136 x ENSG00000213676 x ENSG00000144848 x ENSG00000138363 x ENSG00000177556 x ENSG00000133657 x ENSG00000163399 x ENSG00000203865 x ENSG00000143153 x ENSG00000069849 x ENSG00000174437 x ENSG00000017260 x ENSG00000159199 x ENSG00000154723 x ENSG00000071553 x ENSG00000182220 x ENSG00000117410 x ENSG00000185883 x ENSG00000159720 x ENSG00000113732 x ENSG00000114573 x ENSG00000100554 x ENSG00000131100 x ENSG00000128524 x ENSG00000136888 x ENSG00000047249 x ENSG00000138085 x ENSG00000168488 x ENSG00000115307 x ENSG00000087586 x ENSG00000175756 x ENSG00000155096 x ENSG00000166710 x ENSG00000179913 x ENSG00000086062 x ENSG00000158470 x ENSG00000002330 x ENSG00000151929 x ENSG00000204463 x ENSG00000006453 x ENSG00000175334 x ENSG00000087088 x ENSG00000185825 x ENSG00000107949 x ENSG00000171552 x ENSG00000106635 x ENSG00000186174 x ENSG00000236824 x ENSG00000126581 x ENSG00000123095 x ENSG00000015475 x ENSG00000110330 x ENSG00000089685 x ENSG00000106605 x ENSG00000090013 x ENSG00000176171 x ENSG00000145919 x ENSG00000163170 x ENSG00000164713 x ENSG00000254999 x ENSG00000174744 x ENSG00000172270 x ENSG00000145741 x ENSG00000154473 x ENSG00000106245 x ENSG00000112578 x ENSG00000082153 x ENSG00000136261 x ENSG00000137720 x ENSG00000110696 x ENSG00000175573 x ENSG00000111678 x ENSG00000133935 x ENSG00000087302 x ENSG00000156411 x ENSG00000166920 x ENSG00000167644 x ENSG00000167747 x ENSG00000104979 x ENSG00000197982 x ENSG00000143612 x ENSG00000108561 x ENSG00000243449 x ENSG00000113583 x ENSG00000112308 x ENSG00000146540 x ENSG00000165233 x ENSG00000135932 x ENSG00000172137 x ENSG00000179218 x ENSG00000128595 x ENSG00000111530 x ENSG00000171302 x ENSG00000127022 x ENSG00000131236 x ENSG00000042493 x ENSG00000014216 x ENSG00000162909 x ENSG00000126247 x ENSG00000135387 x ENSG00000116489 x ENSG00000198898 x ENSG00000077549 x ENSG00000198286 x ENSG00000153048 x ENSG00000142453 x ENSG00000110619 x ENSG00000166734 x ENSG00000196954 x ENSG00000153113 x ENSG00000105974 x ENSG00000159228 x ENSG00000160200 x ENSG00000108468 x ENSG00000122565 x ENSG00000108588 x ENSG00000175602 x ENSG00000136280 x ENSG00000134057 x ENSG00000100814 x ENSG00000157456 x ENSG00000112237 x ENSG00000110092 x ENSG00000112576 x ENSG00000113328 x ENSG00000134480 x ENSG00000118816 x ENSG00000166226 x ENSG00000163468 x ENSG00000115484 x ENSG00000150753 x ENSG00000146731 x ENSG00000135624 x ENSG00000156261 x ENSG00000156535 x ENSG00000177697 x ENSG00000135535 x ENSG00000103855 x ENSG00000026508 x ENSG00000117335 x ENSG00000196776 x ENSG00000135404 x ENSG00000125726 x ENSG00000019582 x ENSG00000110651 x ENSG00000085117 x ENSG00000010278 x ENSG00000151465 x ENSG00000117399 x ENSG00000176386 x ENSG00000105401 x ENSG00000163171 x ENSG00000179604 x ENSG00000158985 x ENSG00000170779 x ENSG00000146670 x ENSG00000164649 x ENSG00000039068 x ENSG00000103502 x ENSG00000170312 x ENSG00000102225 x ENSG00000111328 x ENSG00000167797 x ENSG00000135446 x ENSG00000108465 x ENSG00000134058 x ENSG00000100526 x ENSG00000091527 x ENSG00000172216 x ENSG00000123219 x ENSG00000138180 x ENSG00000166037 x ENSG00000143418 x ENSG00000147400 x ENSG00000172757 x ENSG00000163320 x ENSG00000172586 x ENSG00000250479 x ENSG00000106153 x ENSG00000106554 x ENSG00000125611 x ENSG00000170791 x ENSG00000110721 x ENSG00000131165 x ENSG00000255112 x ENSG00000130724 x ENSG00000101421 x ENSG00000123989 x ENSG00000185043 x ENSG00000099622 x ENSG00000179862 x ENSG00000136026 x ENSG00000173207 x ENSG00000123975 x ENSG00000157224 x ENSG00000189143 x ENSG00000181885 x ENSG00000213719 x ENSG00000169504 x ENSG00000113282 x ENSG00000115295 x ENSG00000128973 x ENSG00000074201 x ENSG00000104853 x ENSG00000049656 x ENSG00000171603 x ENSG00000122705 x ENSG00000141367 x ENSG00000120885 x ENSG00000103121 x ENSG00000162368 x ENSG00000091317 x ENSG00000153551 x ENSG00000169714 x ENSG00000100528 x ENSG00000143771 x ENSG00000064666 x ENSG00000117519 x ENSG00000158435 x ENSG00000198791 x ENSG00000155508 x ENSG00000137161 x ENSG00000106603 x ENSG00000183978 x ENSG00000181924 x ENSG00000068120 x ENSG00000182871 x ENSG00000142156 x ENSG00000130309 x ENSG00000140365 x ENSG00000149600 x ENSG00000093010 x ENSG00000165644 x ENSG00000122218 x ENSG00000129083 x ENSG00000184432 x ENSG00000105669 x ENSG00000181789 x ENSG00000172301 x ENSG00000141030 x ENSG00000121022 x ENSG00000168090 x ENSG00000198612 x ENSG00000111481 x ENSG00000115520 x ENSG00000172725 x ENSG00000110880 x ENSG00000103187 x ENSG00000166260 x ENSG00000178449 x ENSG00000138495 x ENSG00000131143 x ENSG00000178741 x ENSG00000135940 x ENSG00000111775 x ENSG00000126267 x ENSG00000164919 x ENSG00000112695 x ENSG00000115944 x ENSG00000131174 x ENSG00000127184 x ENSG00000176340 x ENSG00000047457 x ENSG00000108582 x ENSG00000085719 x ENSG00000071894 x ENSG00000110090 x ENSG00000106066 x ENSG00000143162 x ENSG00000213145 x ENSG00000062485 x ENSG00000124207 x ENSG00000113712 x ENSG00000141551 x ENSG00000159176 x ENSG00000170373 x ENSG00000101439 x ENSG00000101441 x ENSG00000160213 x ENSG00000159692 x ENSG00000175029 x ENSG00000175826 x ENSG00000175215 x ENSG00000164932 x ENSG00000044115 x ENSG00000119326 x ENSG00000168036 x ENSG00000171793 x ENSG00000064601 x ENSG00000164733 x ENSG00000109861 x ENSG00000117984 x ENSG00000103811 x ENSG00000135047 x ENSG00000101160 x ENSG00000085733 x ENSG00000180891 x ENSG00000112514 x ENSG00000150316 x ENSG00000006210 x ENSG00000163735 x ENSG00000169429 x ENSG00000171604 x ENSG00000008283 x ENSG00000166347 x ENSG00000103018 x ENSG00000051523 x ENSG00000179091 x ENSG00000172115 x ENSG00000001630 x ENSG00000120306 x ENSG00000129562 x ENSG00000173402 x ENSG00000226950 x ENSG00000112977 x ENSG00000132676 x ENSG00000071626 x ENSG00000183283 x ENSG00000155368 x ENSG00000136279 x ENSG00000136485 x ENSG00000057019 x ENSG00000110063 x ENSG00000129187 x ENSG00000175203 x ENSG00000104671 x ENSG00000179958 x ENSG00000167986 x ENSG00000168209 x ENSG00000244038 x ENSG00000204580 x ENSG00000099977 x ENSG00000079785 x ENSG00000100201 x ENSG00000088205 x ENSG00000165732 x ENSG00000089737 x ENSG00000123136 x ENSG00000215301 x ENSG00000198231 x ENSG00000108654 x ENSG00000110367 x ENSG00000104325 x ENSG00000143753 x ENSG00000124795 x ENSG00000139726 x ENSG00000136986 x ENSG00000185000 x ENSG00000114956 x ENSG00000116133 x ENSG00000172893 x ENSG00000228716 x ENSG00000095059 x ENSG00000100612 x ENSG00000109606 x ENSG00000089876 x ENSG00000135829 x ENSG00000131504 x ENSG00000130826 x ENSG00000107984 x ENSG00000150768 x ENSG00000119689 x ENSG00000161249 x ENSG00000086061 x ENSG00000132002 x ENSG00000090520 x ENSG00000105993 x ENSG00000077232 x ENSG00000110011 x ENSG00000101152 x ENSG00000168259 x ENSG00000213551 x ENSG00000079805 x ENSG00000123992 x ENSG00000112667 x ENSG00000101457 x ENSG00000172269 x ENSG00000000419 x ENSG00000176978 x ENSG00000162961 x ENSG00000136048 x ENSG00000175550 x ENSG00000046604 x ENSG00000125868 x ENSG00000168393 x ENSG00000120875 x ENSG00000138166 x ENSG00000139318 x ENSG00000128951 x ENSG00000088986 x ENSG00000264364 x ENSG00000125971 x ENSG00000146425 x ENSG00000117395 x ENSG00000147155 x ENSG00000123179 x ENSG00000104823 x ENSG00000127884 x ENSG00000167969 x ENSG00000114346 x ENSG00000107223 x ENSG00000164176 x ENSG00000156508 x ENSG00000101210 x ENSG00000114942 x ENSG00000104529 x ENSG00000254772 x ENSG00000167658 x ENSG00000142634 x ENSG00000108883 x ENSG00000110047 x ENSG00000103966 x ENSG00000135373 x ENSG00000149547 x ENSG00000173812 x ENSG00000173674 x ENSG00000198692 x ENSG00000144895 x ENSG00000086232 x ENSG00000119718 x ENSG00000134001 x ENSG00000125977 x ENSG00000130741 x ENSG00000107581 x ENSG00000106263 x ENSG00000100353 x ENSG00000104408 x ENSG00000175390 x ENSG00000130811 x ENSG00000147677 x ENSG00000084623 x ENSG00000178982 x ENSG00000100129 x ENSG00000149100 x ENSG00000156976 x ENSG00000141543 x ENSG00000063046 x ENSG00000135930 x ENSG00000187840 x ENSG00000148730 x ENSG00000114867 x ENSG00000110321 x ENSG00000106682 x ENSG00000100664 x ENSG00000132507 x ENSG00000242372 x ENSG00000163435 x ENSG00000130165 x ENSG00000066322 x ENSG00000012660 x ENSG00000170522 x ENSG00000161671 x ENSG00000125037 x ENSG00000128463 x ENSG00000134153 x ENSG00000102119 x ENSG00000143924 x ENSG00000134531 x ENSG00000142227 x ENSG00000171617 x ENSG00000149218 x ENSG00000074800 x ENSG00000145293 x ENSG00000143420 x ENSG00000120533 x ENSG00000116016 x ENSG00000088367 x ENSG00000224032 x ENSG00000119888 x ENSG00000142627 x ENSG00000063245 x ENSG00000164308 x ENSG00000124882 x ENSG00000113719 x ENSG00000125991 x ENSG00000100632 x ENSG00000068912 x ENSG00000107566 x ENSG00000197930 x ENSG00000089248 x ENSG00000116285 x ENSG00000139684 x ENSG00000104413 x ENSG00000173153 x ENSG00000120705 x ENSG00000140374 x ENSG00000105379 x ENSG00000134954 x ENSG00000175832 x ENSG00000182944 x ENSG00000178896 x ENSG00000092820 x ENSG00000158769 x ENSG00000181104 x ENSG00000164251 x ENSG00000162585 x ENSG00000164687 x ENSG00000168040 x ENSG00000167106 x ENSG00000048828 x ENSG00000114023 x ENSG00000188163 x ENSG00000152102 x ENSG00000124098 x ENSG00000105058 x ENSG00000196937 x ENSG00000153310 x ENSG00000101447 x ENSG00000180921 x ENSG00000182118 x ENSG00000176973 x ENSG00000169710 x ENSG00000164896 x ENSG00000149806 x ENSG00000105202 x ENSG00000100225 x ENSG00000159069 x ENSG00000079459 x ENSG00000160752 x ENSG00000225733 x ENSG00000091483 x ENSG00000115641 x ENSG00000172500 x ENSG00000214253 x ENSG00000173486 x ENSG00000100442 x ENSG00000105701 x ENSG00000196924 x ENSG00000136068 x ENSG00000132589 x ENSG00000175592 x ENSG00000137166 x ENSG00000164379 x ENSG00000075618 x ENSG00000167996 x ENSG00000087086 x ENSG00000162613 x ENSG00000179163 x ENSG00000001036 x ENSG00000140564 x ENSG00000089280 x ENSG00000033170 x ENSG00000089356 x ENSG00000089327 x ENSG00000145907 x ENSG00000138757 x ENSG00000141349 x ENSG00000160211 x ENSG00000170296 x ENSG00000034713 x ENSG00000179271 x ENSG00000117308 x ENSG00000141429 x ENSG00000164574 x ENSG00000119514 x ENSG00000143641 x ENSG00000115339 x ENSG00000089597 x ENSG00000111640 x ENSG00000159131 x ENSG00000234741 x ENSG00000006007 x ENSG00000130513 x ENSG00000203879 x ENSG00000057608 x ENSG00000239857 x ENSG00000006625 x ENSG00000137563 x ENSG00000165678 x ENSG00000055211 x ENSG00000123159 x ENSG00000124767 x ENSG00000108010 x ENSG00000182512 x ENSG00000148672 x ENSG00000135821 x ENSG00000100938 x ENSG00000163655 x ENSG00000146535 x ENSG00000114353 x ENSG00000087460 x ENSG00000078369 x ENSG00000172354 x ENSG00000174021 x ENSG00000134697 x ENSG00000113552 x ENSG00000135677 x ENSG00000135052 x ENSG00000113384 x ENSG00000115806 x ENSG00000120053 x ENSG00000125166 x ENSG00000197858 x ENSG00000063660 x ENSG00000105220 x ENSG00000138271 x ENSG00000013588 x ENSG00000167191 x ENSG00000170412 x ENSG00000169727 x ENSG00000233276 x ENSG00000176153 x ENSG00000211445 x ENSG00000167468 x ENSG00000106070 x ENSG00000177885 x ENSG00000137106 x ENSG00000178719 x ENSG00000030582 x ENSG00000109519 x ENSG00000104518 x ENSG00000148180 x ENSG00000103342 x ENSG00000104687 x ENSG00000197448 x ENSG00000148834 x ENSG00000065621 x ENSG00000084207 x ENSG00000263001 x ENSG00000122034 x ENSG00000172432 x ENSG00000143774 x ENSG00000144366 x ENSG00000074696 x ENSG00000084754 x ENSG00000138029 x ENSG00000128708 x ENSG00000143575 x ENSG00000116478 x ENSG00000171720 x ENSG00000143321 x ENSG00000115677 x ENSG00000051620 x ENSG00000213614 x ENSG00000049860 x ENSG00000100644 x ENSG00000181061 x ENSG00000146066 x ENSG00000169567 x ENSG00000137133 x ENSG00000197903 x ENSG00000206503 x ENSG00000234745 x ENSG00000204525 x ENSG00000204287 x ENSG00000204592 x ENSG00000204642 x ENSG00000206341 x ENSG00000101294 x ENSG00000137309 x ENSG00000149948 x ENSG00000189403 x ENSG00000164104 x ENSG00000113161 x ENSG00000112972 x ENSG00000205581 x ENSG00000198830 x ENSG00000118418 x ENSG00000177733 x ENSG00000135486 x ENSG00000122566 x ENSG00000170144 x ENSG00000197451 x ENSG00000092199 x ENSG00000138668 x ENSG00000152795 x ENSG00000169813 x ENSG00000169045 x ENSG00000096746 x ENSG00000165119 x ENSG00000104824 x ENSG00000099783 x ENSG00000153187 x ENSG00000105323 x ENSG00000127483 x ENSG00000115756 x ENSG00000165704 x ENSG00000230989 x ENSG00000072506 x ENSG00000198189 x ENSG00000149084 x ENSG00000133835 x ENSG00000080824 x ENSG00000096384 x ENSG00000166598 x ENSG00000170606 x ENSG00000044574 x ENSG00000109971 x ENSG00000113013 x ENSG00000106211 x ENSG00000081870 x ENSG00000120694 x ENSG00000109854 x ENSG00000149428 x ENSG00000134330 x ENSG00000067704 x ENSG00000115738 x ENSG00000138413 x ENSG00000182054 x ENSG00000067829 x ENSG00000067064 x ENSG00000160888 x ENSG00000137331 x ENSG00000165949 x ENSG00000119632 x ENSG00000068079 x ENSG00000137965 x ENSG00000126709 x ENSG00000119922 x ENSG00000119917 x ENSG00000185885 x ENSG00000142089 x ENSG00000027697 x ENSG00000159128 x ENSG00000089289 x ENSG00000073792 x ENSG00000136231 x ENSG00000141753 x ENSG00000163453 x ENSG00000113141 x ENSG00000150782 x ENSG00000143621 x ENSG00000129351 x ENSG00000166333 x ENSG00000132305 x ENSG00000177971 x ENSG00000136718 x ENSG00000141401 x ENSG00000104331 x ENSG00000106348 x ENSG00000178035 x ENSG00000203485 x ENSG00000165458 x ENSG00000186480 x ENSG00000205339 x ENSG00000140575 x ENSG00000184216 x 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ENSG00000075142 ENSG00000140319 ENSG00000100883 ENSG00000167881 ENSG00000143742 ENSG00000161547 ENSG00000112081 ENSG00000100650 ENSG00000124193 ENSG00000115875 ENSG00000111786 ENSG00000138385 ENSG00000106028 ENSG00000176101 ENSG00000163479 ENSG00000114850 ENSG00000180879 ENSG00000149136 ENSG00000160075 ENSG00000100380 ENSG00000149418 ENSG00000110080 ENSG00000214530 ENSG00000010270 ENSG00000084090 ENSG00000115415 ENSG00000168610 ENSG00000166888 ENSG00000124214 ENSG00000113739 ENSG00000164647 ENSG00000167323 ENSG00000168439 ENSG00000102572 ENSG00000198648 ENSG00000117632 ENSG00000148175 ENSG00000165283 ENSG00000023734 ENSG00000101846 ENSG00000134910 ENSG00000163527 ENSG00000127952 ENSG00000113387 ENSG00000163541 ENSG00000196562 ENSG00000129103 ENSG00000116030 ENSG00000188612 ENSG00000184900 ENSG00000164828 ENSG00000092201 ENSG00000213246 ENSG00000196235 ENSG00000148248 ENSG00000108639 ENSG00000008282 ENSG00000162298 ENSG00000184292 ENSG00000166337 ENSG00000270647 ENSG00000166012 ENSG00000178913 ENSG00000158710 ENSG00000177156 ENSG00000136560 ENSG00000120948 ENSG00000106052 ENSG00000171530 ENSG00000105254 ENSG00000124659 ENSG00000136270 ENSG00000187735 ENSG00000180964 ENSG00000154582 ENSG00000148737 ENSG00000110719 ENSG00000134827 ENSG00000120438 ENSG00000099797 ENSG00000135269 ENSG00000088992 ENSG00000198176 ENSG00000160182 ENSG00000160181 ENSG00000160180 ENSG00000114354 ENSG00000003436 ENSG00000072274 ENSG00000163235 ENSG00000120708 ENSG00000163513 ENSG00000177426 ENSG00000198959 ENSG00000152291 ENSG00000176946 ENSG00000163634 ENSG00000151500 ENSG00000151923 ENSG00000126768 ENSG00000265354 ENSG00000150779 ENSG00000100575 ENSG00000113845 ENSG00000102265 ENSG00000035862 ENSG00000100234 ENSG00000142910 ENSG00000137221 ENSG00000119139 ENSG00000167900 ENSG00000163931 ENSG00000160606 ENSG00000169908 ENSG00000064115 ENSG00000100926 ENSG00000125304 ENSG00000077147 ENSG00000232112 ENSG00000135926 ENSG00000155957 ENSG00000139644 ENSG00000141524 ENSG00000170348 ENSG00000086598 ENSG00000166557 ENSG00000158604 ENSG00000184840 ENSG00000134291 ENSG00000152558 ENSG00000171202 ENSG00000171204 ENSG00000244187 ENSG00000105677 ENSG00000096092 ENSG00000137210 ENSG00000111843 ENSG00000121895 ENSG00000134851 ENSG00000105518 ENSG00000149932 ENSG00000089063 ENSG00000106609 ENSG00000134825 ENSG00000182087 ENSG00000112697 ENSG00000182107 ENSG00000151715 ENSG00000183726 ENSG00000116209 ENSG00000135211 ENSG00000196187 ENSG00000109084 ENSG00000175348 ENSG00000120802 ENSG00000160183 ENSG00000137648 ENSG00000034510 ENSG00000205542 ENSG00000164897 ENSG00000185215 ENSG00000120889 ENSG00000006327 ENSG00000157873 ENSG00000146072 ENSG00000125657 ENSG00000145901 ENSG00000083312 ENSG00000136205 ENSG00000131746 ENSG00000141232 ENSG00000173726 ENSG00000100216 ENSG00000130204 ENSG00000175768 ENSG00000214736 ENSG00000196683 ENSG00000198900 ENSG00000131747 ENSG00000136827 ENSG00000141510 ENSG00000146242 ENSG00000101150 ENSG00000111669 ENSG00000140416 ENSG00000143549 ENSG00000167460 ENSG00000163870 ENSG00000133112 ENSG00000088325 ENSG00000136527 ENSG00000076604 ENSG00000067167 ENSG00000126602 ENSG00000170043 ENSG00000054116 ENSG00000196655 ENSG00000181029 ENSG00000101255 ENSG00000121060 ENSG00000130726 ENSG00000171206 ENSG00000153827 ENSG00000071539 ENSG00000173113 ENSG00000100991 ENSG00000149743 ENSG00000074319 ENSG00000182704 ENSG00000211460 ENSG00000117472 ENSG00000106537 ENSG00000108219 ENSG00000099282 ENSG00000140391 ENSG00000100300 ENSG00000128311 ENSG00000215845 ENSG00000136295 ENSG00000123416 ENSG00000167553 ENSG00000127824 ENSG00000196230 ENSG00000188229 ENSG00000176014 ENSG00000131462 ENSG00000130640 ENSG00000178952 ENSG00000104723 ENSG00000151239 ENSG00000128791 ENSG00000136810 ENSG00000265972 ENSG00000141759 ENSG00000198431 ENSG00000176890 ENSG00000160201 ENSG00000063244 ENSG00000130985 ENSG00000126261 ENSG00000221983 ENSG00000185262 ENSG00000143569 ENSG00000170315 ENSG00000150991 ENSG00000213886 ENSG00000077721 ENSG00000175063 ENSG00000131508 ENSG00000109332 ENSG00000170142 ENSG00000170035 ENSG00000186591 ENSG00000185651 ENSG00000156587 ENSG00000130725 ENSG00000177889 ENSG00000108106 ENSG00000077152 ENSG00000169139 ENSG00000159202 ENSG00000009335 ENSG00000198258 ENSG00000135018 ENSG00000144224 ENSG00000118939 ENSG00000143179 ENSG00000175567 ENSG00000143222 ENSG00000148154 ENSG00000109814 ENSG00000169764 ENSG00000115446 ENSG00000110057 ENSG00000076248 ENSG00000183696 ENSG00000184076 ENSG00000127540 ENSG00000156467 ENSG00000010256 ENSG00000140740 ENSG00000169021 ENSG00000173660 ENSG00000164405 ENSG00000105176 ENSG00000188690 ENSG00000105698 ENSG00000101557 ENSG00000124422 ENSG00000168883 ENSG00000011260 ENSG00000115652 ENSG00000126756 ENSG00000049245 ENSG00000168899 ENSG00000118640 ENSG00000101558 ENSG00000108828 ENSG00000155959 ENSG00000035403 ENSG00000165280 ENSG00000213585 ENSG00000165637 ENSG00000078668 ENSG00000112715 ENSG00000167397 ENSG00000062716 ENSG00000154978 ENSG00000131475 ENSG00000122958 ENSG00000160948 ENSG00000111237 ENSG00000069329 ENSG00000139722 ENSG00000100749 ENSG00000100568 ENSG00000254635 ENSG00000140105 ENSG00000132471 ENSG00000071127 ENSG00000141580 ENSG00000140395 ENSG00000105583 ENSG00000101443 ENSG00000109501 ENSG00000176871 ENSG00000146457 ENSG00000018408 ENSG00000100219 ENSG00000108039 ENSG00000082898 ENSG00000124571 ENSG00000184575 ENSG00000079246 ENSG00000196419 ENSG00000137693 ENSG00000065978 ENSG00000060138 ENSG00000161179 ENSG00000176105 ENSG00000174851 ENSG00000130733 ENSG00000137207 ENSG00000119820 ENSG00000106636 ENSG00000136758 ENSG00000119801 ENSG00000166913 ENSG00000108953 ENSG00000170027 ENSG00000128245 ENSG00000134308 ENSG00000164924 ENSG00000100811 ENSG00000163874 ENSG00000065548 ENSG00000105939 ENSG00000160446 ENSG00000171307 ENSG00000180776 ENSG00000174165 ENSG00000136247 ENSG00000153786 ENSG00000104231 ENSG00000086666 ENSG00000177410 ENSG00000185650 ENSG00000162300 ENSG00000100711 ENSG00000146007 ENSG00000167635 ENSG00000010244 ENSG00000198546 ENSG00000106400 ENSG00000273611 ENSG00000109917 ENSG00000122952 ENSG00000159840 x 2023-03-14T22:49:32.230009+00:00 x e108_eg55_p17_0254fbf

Part 18: Visualizations of the upregualted and the downregulated genes

gprofiler2::gostplot(Upregulated_Gprofiler_validated) %>% plotly::layout(title = "Upregulated genes ", font = list(size = 10))

Continuing

gprofiler2::gostplot(Downregulated_Gprofiler_validated) %>% plotly::layout(title = "Downregulated genes ", font = list(size = 10))

Part 19: GProfiler Analyses for the merged dataset

Complete_Gprofiler_Analyses <- gprofiler2::gost(query = merged_hits$Gene_symbol, 
                                  organism = "hsapiens", 
                                  exclude_iea = TRUE,
                                  correction_method = "fdr",
                                  sources = c("GO:BP", "REAC", "WP"))

Complete_Gprofiler_Analyses_filtered <- data.frame(term_name = Complete_Gprofiler_Analyses$result$term_name[Complete_Gprofiler_Analyses$result$term_size < 200 &
                                               Complete_Gprofiler_Analyses$result$term_size > 1],
  term_id = Complete_Gprofiler_Analyses$result$term_id[Complete_Gprofiler_Analyses$result$term_size < 200 &
                                           Complete_Gprofiler_Analyses$result$term_size > 1],
  source = Complete_Gprofiler_Analyses$result$source[Complete_Gprofiler_Analyses$result$term_size < 200 &
                                         Complete_Gprofiler_Analyses$result$term_size > 1])

length(Complete_Gprofiler_Analyses_filtered$term_name)

## [1] 1927

knitr::kable(head(Complete_Gprofiler_Analyses, 1), format = "html")

query significant p_value term_size query_size intersection_size precision recall term_id source term_name effective_domain_size source_order parents query_1 TRUE 0.0000000 8618 9028 5723 0.6339167 0.6640752 GO:0044237 GO:BP cellular metabolic process 16307 11638 GO:00081…. query_1 TRUE 0.0000000 9002 9028 5874 0.6506424 0.6525217 GO:0044238 GO:BP primary metabolic process 16307 11639 GO:0008152 query_1 TRUE 0.0000000 10003 9028 6410 0.7100133 0.6408078 GO:0008152 GO:BP metabolic process 16307 3213 GO:0008150 query_1 TRUE 0.0000000 2734 9028 2154 0.2385911 0.7878566 GO:0044260 GO:BP cellular macromolecule metabolic process 16307 11650 GO:00431…. query_1 TRUE 0.0000000 8581 9028 5629 0.6235047 0.6559842 GO:0006807 GO:BP nitrogen compound metabolic process 16307 2557 GO:0008152 query_1 TRUE 0.0000000 9567 9028 6143 0.6804386 0.6421031 GO:0071704 GO:BP organic substance metabolic process 16307 17953 GO:0008152 query_1 TRUE 0.0000000 8109 9028 5282 0.5850687 0.6513750 GO:0043170 GO:BP macromolecule metabolic process 16307 11211 GO:0071704 query_1 TRUE 0.0000000 5587 9028 3778 0.4184759 0.6762126 GO:0034641 GO:BP cellular nitrogen compound metabolic process 16307 9210 GO:00068…. query_1 TRUE 0.0000000 5451 9028 3686 0.4082853 0.6762062 GO:1901564 GO:BP organonitrogen compound metabolic process 16307 22679 GO:00068…. query_1 TRUE 0.0000000 4506 9028 3108 0.3442623 0.6897470 GO:0019538 GO:BP protein metabolic process 16307 6224 GO:00431…. query_1 TRUE 0.0000000 5202 9028 3465 0.3838059 0.6660900 GO:0046483 GO:BP heterocycle metabolic process 16307 12974 GO:0044237 query_1 TRUE 0.0000000 5057 9028 3379 0.3742800 0.6681827 GO:0006139 GO:BP nucleobase-containing compound metabolic process 16307 2036 GO:00067…. query_1 TRUE 0.0000000 5086 9028 3388 0.3752769 0.6661424 GO:0044249 GO:BP cellular biosynthetic process 16307 11645 GO:00090…. query_1 TRUE 0.0000000 1637 9028 1268 0.1404519 0.7745877 GO:0033554 GO:BP cellular response to stress 16307 8768 GO:00069…. query_1 TRUE 0.0000000 5147 9028 3422 0.3790430 0.6648533 GO:1901576 GO:BP organic substance biosynthetic process 16307 22687 GO:00090…. query_1 TRUE 0.0000000 5236 9028 3473 0.3846921 0.6632926 GO:0006725 GO:BP cellular aromatic compound metabolic process 16307 2497 GO:0044237 query_1 TRUE 0.0000000 5207 9028 3451 0.3822552 0.6627617 GO:0009058 GO:BP biosynthetic process 16307 3326 GO:0008152 query_1 TRUE 0.0000000 5424 9028 3571 0.3955472 0.6583702 GO:1901360 GO:BP organic cyclic compound metabolic process 16307 22497 GO:0071704 query_1 TRUE 0.0000000 1382 9028 1091 0.1208463 0.7894356 GO:0046907 GO:BP intracellular transport 16307 13236 GO:00068…. query_1 TRUE 0.0000000 4572 9028 3062 0.3391670 0.6697288 GO:0090304 GO:BP nucleic acid metabolic process 16307 19342 GO:00061…. query_1 TRUE 0.0000000 3197 9028 2234 0.2474524 0.6987801 GO:0043412 GO:BP macromolecule modification 16307 11326 GO:0043170 query_1 TRUE 0.0000000 1818 9028 1368 0.1515286 0.7524752 GO:0044248 GO:BP cellular catabolic process 16307 11644 GO:00090…. query_1 TRUE 0.0000000 2153 9028 1568 0.1736819 0.7282861 GO:0009056 GO:BP catabolic process 16307 3324 GO:0008152 query_1 TRUE 0.0000000 1716 9028 1278 0.1415596 0.7447552 GO:0051649 GO:BP establishment of localization in cell 16307 14733 GO:00512…. query_1 TRUE 0.0000000 1175 9028 923 0.1022375 0.7855319 GO:0009057 GO:BP macromolecule catabolic process 16307 3325 GO:00431…. query_1 TRUE 0.0000000 4233 9028 2817 0.3120292 0.6654855 GO:0009059 GO:BP macromolecule biosynthetic process 16307 3327 GO:00431…. query_1 TRUE 0.0000000 2992 9028 2072 0.2295082 0.6925134 GO:0036211 GO:BP protein modification process 16307 10066 GO:00195…. query_1 TRUE 0.0000000 882 9028 720 0.0797519 0.8163265 GO:0044265 GO:BP cellular macromolecule catabolic process 16307 11653 GO:00090…. query_1 TRUE 0.0000000 4274 9028 2832 0.3136907 0.6626111 GO:0044271 GO:BP cellular nitrogen compound biosynthetic process 16307 11656 GO:00346…. query_1 TRUE 0.0000000 858 9028 701 0.0776473 0.8170163 GO:0006396 GO:BP RNA processing 16307 2220 GO:00104…. query_1 TRUE 0.0000000 2733 9028 1901 0.2105671 0.6955726 GO:0051641 GO:BP cellular localization 16307 14725 GO:00099…. query_1 TRUE 0.0000000 5255 9028 3398 0.3763846 0.6466223 GO:0010467 GO:BP gene expression 16307 4270 GO:0043170 query_1 TRUE 0.0000000 1495 9028 1119 0.1239477 0.7484950 GO:1901566 GO:BP organonitrogen compound biosynthetic process 16307 22681 GO:19015…. query_1 TRUE 0.0000000 999 9028 792 0.0877271 0.7927928 GO:0034645 GO:BP cellular macromolecule biosynthetic process 16307 9214 GO:00090…. query_1 TRUE 0.0000000 3183 9028 2167 0.2400310 0.6808043 GO:0006996 GO:BP organelle organization 16307 2686 GO:0016043 query_1 TRUE 0.0000000 1752 9028 1283 0.1421134 0.7323059 GO:1901575 GO:BP organic substance catabolic process 16307 22686 GO:00090…. query_1 TRUE 0.0000000 4090 9028 2706 0.2997342 0.6616137 GO:0016070 GO:BP RNA metabolic process 16307 5254 GO:0090304 query_1 TRUE 0.0000000 14876 9028 8523 0.9440629 0.5729363 GO:0009987 GO:BP cellular process 16307 3905 GO:0008150 query_1 TRUE 0.0000000 776 9028 635 0.0703367 0.8182990 GO:0006974 GO:BP cellular response to DNA damage stimulus 16307 2675 GO:0033554 query_1 TRUE 0.0000000 767 9028 625 0.0692291 0.8148631 GO:0033365 GO:BP protein localization to organelle 16307 8652 GO:0008104 query_1 TRUE 0.0000000 4975 9028 3205 0.3550066 0.6442211 GO:0031323 GO:BP regulation of cellular metabolic process 16307 7549 GO:00192…. query_1 TRUE 0.0000000 598 9028 506 0.0560479 0.8461538 GO:0006412 GO:BP translation 16307 2234 GO:00104…. query_1 TRUE 0.0000000 1880 9028 1347 0.1492025 0.7164894 GO:0070727 GO:BP cellular macromolecule localization 16307 17331 GO:00330…. query_1 TRUE 0.0000000 4978 9028 3201 0.3545636 0.6430293 GO:0051171 GO:BP regulation of nitrogen compound metabolic process 16307 14399 GO:00068…. query_1 TRUE 0.0000000 1874 9028 1341 0.1485379 0.7155816 GO:0008104 GO:BP protein localization 16307 3211 GO:0070727 query_1 TRUE 0.0000000 820 9028 657 0.0727736 0.8012195 GO:0000278 GO:BP mitotic cell cycle 16307 80 GO:0007049 query_1 TRUE 0.0000000 620 9028 518 0.0573770 0.8354839 GO:0043043 GO:BP peptide biosynthetic process 16307 11131 GO:00065…. query_1 TRUE 0.0000000 738 9028 599 0.0663491 0.8116531 GO:0043604 GO:BP amide biosynthetic process 16307 11452 GO:00436…. query_1 TRUE 0.0000000 5100 9028 3264 0.3615419 0.6400000 GO:0080090 GO:BP regulation of primary metabolic process 16307 18924 GO:00192…. query_1 TRUE 0.0000000 2246 9028 1566 0.1734603 0.6972395 GO:0033036 GO:BP macromolecule localization 16307 8466 GO:0051179 query_1 TRUE 0.0000000 856 9028 678 0.0750997 0.7920561 GO:0030163 GO:BP protein catabolic process 16307 7090 GO:00090…. query_1 TRUE 0.0000000 392 9028 351 0.0388790 0.8954082 GO:0022613 GO:BP ribonucleoprotein complex biogenesis 16307 7017 GO:0044085 query_1 TRUE 0.0000000 680 9028 556 0.0615862 0.8176471 GO:1903047 GO:BP mitotic cell cycle process 16307 23916 GO:00002…. query_1 TRUE 0.0000000 690 9028 562 0.0622508 0.8144928 GO:0051603 GO:BP proteolysis involved in protein catabolic process 16307 14691 GO:00065…. query_1 TRUE 0.0000000 763 9028 612 0.0677891 0.8020970 GO:0006518 GO:BP peptide metabolic process 16307 2306 GO:00436…. query_1 TRUE 0.0000000 604 9028 502 0.0556048 0.8311258 GO:0043632 GO:BP modification-dependent macromolecule catabolic process 16307 11474 GO:0044265 query_1 TRUE 0.0000000 5580 9028 3529 0.3908950 0.6324373 GO:0071840 GO:BP cellular component organization or biogenesis 16307 18026 GO:0009987 query_1 TRUE 0.0000000 1006 9028 774 0.0857333 0.7693837 GO:0043603 GO:BP amide metabolic process 16307 11451 GO:0006807 query_1 TRUE 0.0000000 592 9028 493 0.0546079 0.8327703 GO:0019941 GO:BP modification-dependent protein catabolic process 16307 6456 GO:00436…. query_1 TRUE 0.0000000 704 9028 570 0.0631369 0.8096591 GO:0006886 GO:BP intracellular protein transport 16307 2614 GO:00081…. query_1 TRUE 0.0000000 1149 9028 866 0.0959238 0.7536989 GO:1901565 GO:BP organonitrogen compound catabolic process 16307 22680 GO:19015…. query_1 TRUE 0.0000000 1430 9028 1046 0.1158618 0.7314685 GO:0007049 GO:BP cell cycle 16307 2724 GO:0009987 query_1 TRUE 0.0000000 584 9028 485 0.0537218 0.8304795 GO:0006511 GO:BP ubiquitin-dependent protein catabolic process 16307 2301 GO:0019941 query_1 TRUE 0.0000000 884 9028 688 0.0762074 0.7782805 GO:0006259 GO:BP DNA metabolic process 16307 2134 GO:00442…. query_1 TRUE 0.0000000 5908 9028 3702 0.4100576 0.6266080 GO:0019222 GO:BP regulation of metabolic process 16307 5935 GO:00081…. query_1 TRUE 0.0000000 928 9028 711 0.0787550 0.7661638 GO:0051726 GO:BP regulation of cell cycle 16307 14784 GO:00070…. query_1 TRUE 0.0000000 610 9028 497 0.0550510 0.8147541 GO:0016071 GO:BP mRNA metabolic process 16307 5255 GO:0016070 query_1 TRUE 0.0000000 2559 9028 1731 0.1917368 0.6764361 GO:0051173 GO:BP positive regulation of nitrogen compound metabolic process 16307 14401 GO:00068…. query_1 TRUE 0.0000000 2062 9028 1427 0.1580638 0.6920466 GO:0051246 GO:BP regulation of protein metabolic process 16307 14445 GO:00195…. query_1 TRUE 0.0000000 1125 9028 836 0.0926008 0.7431111 GO:0045184 GO:BP establishment of protein localization 16307 12077 GO:00081…. query_1 TRUE 0.0000000 5443 9028 3417 0.3784891 0.6277788 GO:0060255 GO:BP regulation of macromolecule metabolic process 16307 15399 GO:00192…. query_1 TRUE 0.0000000 2770 9028 1850 0.2049180 0.6678700 GO:0044085 GO:BP cellular component biogenesis 16307 11606 GO:0071840 query_1 TRUE 0.0000000 2521 9028 1700 0.1883031 0.6743356 GO:0031325 GO:BP positive regulation of cellular metabolic process 16307 7551 GO:00098…. query_1 TRUE 0.0000000 1622 9028 1140 0.1262738 0.7028360 GO:0045935 GO:BP positive regulation of nucleobase-containing compound metabolic process 16307 12505 GO:00061…. query_1 TRUE 0.0000000 247 9028 228 0.0252548 0.9230769 GO:0042254 GO:BP ribosome biogenesis 16307 10687 GO:0022613 query_1 TRUE 0.0000000 1028 9028 763 0.0845148 0.7422179 GO:0015031 GO:BP protein transport 16307 4945 GO:00451…. query_1 TRUE 0.0000000 510 9028 418 0.0463004 0.8196078 GO:0006281 GO:BP DNA repair 16307 2153 GO:00062…. query_1 TRUE 0.0000000 1121 9028 820 0.0908285 0.7314897 GO:0022402 GO:BP cell cycle process 16307 6990 GO:00070…. query_1 TRUE 0.0000000 5407 9028 3369 0.3731724 0.6230812 GO:0016043 GO:BP cellular component organization 16307 5233 GO:0071840 query_1 TRUE 0.0000000 843 9028 639 0.0707798 0.7580071 GO:0009894 GO:BP regulation of catabolic process 16307 3848 GO:00090…. query_1 TRUE 0.0000000 3176 9028 2072 0.2295082 0.6523929 GO:0009893 GO:BP positive regulation of metabolic process 16307 3847 GO:00081…. query_1 TRUE 0.0000000 492 9028 402 0.0445281 0.8170732 GO:0010498 GO:BP proteasomal protein catabolic process 16307 4287 GO:00301…. query_1 TRUE 0.0000000 548 9028 440 0.0487373 0.8029197 GO:0034660 GO:BP ncRNA metabolic process 16307 9222 GO:0016070 query_1 TRUE 0.0000000 423 9028 353 0.0391006 0.8345154 GO:0043161 GO:BP proteasome-mediated ubiquitin-dependent protein catabolic process 16307 11206 GO:00065…. query_1 TRUE 0.0000000 1497 9028 1052 0.1165264 0.7027388 GO:0010557 GO:BP positive regulation of macromolecule biosynthetic process 16307 4327 GO:00090…. query_1 TRUE 0.0000000 1572 9028 1098 0.1216216 0.6984733 GO:0031328 GO:BP positive regulation of cellular biosynthetic process 16307 7554 GO:00098…. query_1 TRUE 0.0000000 2886 9028 1894 0.2097918 0.6562717 GO:0010604 GO:BP positive regulation of macromolecule metabolic process 16307 4369 GO:00098…. query_1 TRUE 0.0000000 822 9028 621 0.0687860 0.7554745 GO:0070647 GO:BP protein modification by small protein conjugation or removal 16307 17286 GO:0036211 query_1 TRUE 0.0000000 694 9028 535 0.0592601 0.7708934 GO:0031329 GO:BP regulation of cellular catabolic process 16307 7555 GO:00098…. query_1 TRUE 0.0000000 1598 9028 1110 0.1229508 0.6946183 GO:0009891 GO:BP positive regulation of biosynthetic process 16307 3845 GO:00090…. query_1 TRUE 0.0000000 3639 9028 2332 0.2583075 0.6408354 GO:0018130 GO:BP heterocycle biosynthetic process 16307 5537 GO:00442…. query_1 TRUE 0.0000000 3507 9028 2254 0.2496677 0.6427146 GO:0010556 GO:BP regulation of macromolecule biosynthetic process 16307 4326 GO:00090…. query_1 TRUE 0.0000000 390 9028 327 0.0362206 0.8384615 GO:0008380 GO:BP RNA splicing 16307 3277 GO:0006396 query_1 TRUE 0.0000000 478 9028 388 0.0429774 0.8117155 GO:0061919 GO:BP process utilizing autophagic mechanism 16307 16756 GO:0009987 query_1 TRUE 0.0000000 478 9028 388 0.0429774 0.8117155 GO:0006914 GO:BP autophagy 16307 2635 GO:00442…. query_1 TRUE 0.0000000 681 9028 525 0.0581524 0.7709251 GO:0032446 GO:BP protein modification by small protein conjugation 16307 8029 GO:0070647 query_1 TRUE 0.0000000 3625 9028 2322 0.2571998 0.6405517 GO:0031326 GO:BP regulation of cellular biosynthetic process 16307 7552 GO:00098…. query_1 TRUE 0.0000000 1021 9028 746 0.0826318 0.7306562 GO:0033043 GO:BP regulation of organelle organization 16307 8468 GO:00069…. query_1 TRUE 0.0000000 3759 9028 2400 0.2658396 0.6384677 GO:1901362 GO:BP organic cyclic compound biosynthetic process 16307 22499 GO:19013…. query_1 TRUE 0.0000000 367 9028 310 0.0343376 0.8446866 GO:0072594 GO:BP establishment of protein localization to organelle 16307 18564 GO:00333…. query_1 TRUE 0.0000000 1435 9028 1006 0.1114311 0.7010453 GO:0051254 GO:BP positive regulation of RNA metabolic process 16307 14453 GO:00106…. query_1 TRUE 0.0000000 3668 9028 2344 0.2596367 0.6390403 GO:0009889 GO:BP regulation of biosynthetic process 16307 3843 GO:00090…. query_1 TRUE 0.0000000 3660 9028 2339 0.2590829 0.6390710 GO:0019219 GO:BP regulation of nucleobase-containing compound metabolic process 16307 5932 GO:00061…. query_1 TRUE 0.0000000 3647 9028 2331 0.2581967 0.6391555 GO:0019438 GO:BP aromatic compound biosynthetic process 16307 6132 GO:00067…. query_1 TRUE 0.0000000 1849 9028 1256 0.1391227 0.6792861 GO:0031324 GO:BP negative regulation of cellular metabolic process 16307 7550 GO:00098…. query_1 TRUE 0.0000000 2430 9028 1607 0.1780018 0.6613169 GO:0009892 GO:BP negative regulation of metabolic process 16307 3846 GO:00081…. query_1 TRUE 0.0000000 480 9028 386 0.0427559 0.8041667 GO:0044770 GO:BP cell cycle phase transition 16307 11905 GO:0022402 query_1 TRUE 0.0000000 3578 9028 2285 0.2531015 0.6386249 GO:0034654 GO:BP nucleobase-containing compound biosynthetic process 16307 9218 GO:00061…. query_1 TRUE 0.0000000 1931 9028 1304 0.1444395 0.6752978 GO:0051172 GO:BP negative regulation of nitrogen compound metabolic process 16307 14400 GO:00068…. query_1 TRUE 0.0000000 2257 9028 1501 0.1662605 0.6650421 GO:0010605 GO:BP negative regulation of macromolecule metabolic process 16307 4370 GO:00098…. query_1 TRUE 0.0000000 391 9028 323 0.0357776 0.8260870 GO:0016570 GO:BP histone modification 16307 5415 GO:0036211 query_1 TRUE 0.0000000 1434 9028 997 0.1104342 0.6952580 GO:0006508 GO:BP proteolysis 16307 2299 GO:0019538 query_1 TRUE 0.0000000 393 9028 324 0.0358883 0.8244275 GO:0034470 GO:BP ncRNA processing 16307 9152 GO:00063…. query_1 TRUE 0.0000000 389 9028 321 0.0355560 0.8251928 GO:0034248 GO:BP regulation of amide metabolic process 16307 9016 GO:00436…. query_1 TRUE 0.0000000 619 9028 477 0.0528356 0.7705977 GO:0010564 GO:BP regulation of cell cycle process 16307 4334 GO:00224…. query_1 TRUE 0.0000000 613 9028 473 0.0523926 0.7716150 GO:0016567 GO:BP protein ubiquitination 16307 5414 GO:0032446 query_1 TRUE 0.0000000 431 9028 350 0.0387683 0.8120650 GO:0010608 GO:BP post-transcriptional regulation of gene expression 16307 4373 GO:0010468 query_1 TRUE 0.0000000 469 9028 375 0.0415374 0.7995736 GO:0007005 GO:BP mitochondrion organization 16307 2692 GO:0006996 query_1 TRUE 0.0000000 385 9028 317 0.0351130 0.8233766 GO:0044772 GO:BP mitotic cell cycle phase transition 16307 11907 GO:00447…. query_1 TRUE 0.0000000 177 9028 165 0.0182765 0.9322034 GO:0006364 GO:BP rRNA processing 16307 2201 GO:00160…. query_1 TRUE 0.0000000 377 9028 310 0.0343376 0.8222812 GO:0006397 GO:BP mRNA processing 16307 2221 GO:00063…. query_1 TRUE 0.0000000 1413 9028 977 0.1082189 0.6914367 GO:0071705 GO:BP nitrogen compound transport 16307 17954 GO:0006810 query_1 TRUE 0.0000000 609 9028 466 0.0516172 0.7651888 GO:0080135 GO:BP regulation of cellular response to stress 16307 18943 GO:00335…. query_1 TRUE 0.0000000 214 9028 192 0.0212672 0.8971963 GO:0016072 GO:BP rRNA metabolic process 16307 5256 GO:0034660 query_1 TRUE 0.0000000 421 9028 339 0.0375498 0.8052257 GO:0007346 GO:BP regulation of mitotic cell cycle 16307 2942 GO:00002…. query_1 TRUE 0.0000000 292 9028 248 0.0274701 0.8493151 GO:0016236 GO:BP macroautophagy 16307 5336 GO:0006914 query_1 TRUE 0.0000000 372 9028 304 0.0336730 0.8172043 GO:1901987 GO:BP regulation of cell cycle phase transition 16307 23055 GO:00105…. query_1 TRUE 0.0000000 1932 9028 1287 0.1425565 0.6661491 GO:0051128 GO:BP regulation of cellular component organization 16307 14357 GO:00160…. query_1 TRUE 0.0000000 231 9028 203 0.0224856 0.8787879 GO:0006260 GO:BP DNA replication 16307 2135 GO:0006259 query_1 TRUE 0.0000000 336 9028 278 0.0307931 0.8273810 GO:0006417 GO:BP regulation of translation 16307 2238 GO:00064…. query_1 TRUE 0.0000000 1305 9028 903 0.1000222 0.6919540 GO:1902680 GO:BP positive regulation of RNA biosynthetic process 16307 23603 GO:00105…. query_1 TRUE 0.0000000 410 9028 328 0.0363314 0.8000000 GO:2000112 GO:BP regulation of cellular macromolecule biosynthetic process 16307 26871 GO:00105…. query_1 TRUE 0.0000000 281 9028 238 0.0263624 0.8469751 GO:1901990 GO:BP regulation of mitotic cell cycle phase transition 16307 23058 GO:00073…. query_1 TRUE 0.0000000 1297 9028 895 0.0991360 0.6900540 GO:0045893 GO:BP positive regulation of DNA-templated transcription 16307 12467 GO:00063…. query_1 TRUE 0.0000000 3379 9028 2138 0.2368188 0.6327316 GO:0051252 GO:BP regulation of RNA metabolic process 16307 14451 GO:00160…. query_1 TRUE 0.0000000 1297 9028 895 0.0991360 0.6900540 GO:1903508 GO:BP positive regulation of nucleic acid-templated transcription 16307 24288 GO:00976…. query_1 TRUE 0.0000000 289 9028 243 0.0269163 0.8408304 GO:0000375 GO:BP RNA splicing, via transesterification reactions 16307 115 GO:0008380 query_1 TRUE 0.0000000 2558 9028 1655 0.1833186 0.6469898 GO:0022607 GO:BP cellular component assembly 16307 7012 GO:00160…. query_1 TRUE 0.0000000 470 9028 367 0.0406513 0.7808511 GO:0051052 GO:BP regulation of DNA metabolic process 16307 14305 GO:00062…. query_1 TRUE 0.0000000 2361 9028 1536 0.1701374 0.6505718 GO:0006793 GO:BP phosphorus metabolic process 16307 2548 GO:0044237 query_1 TRUE 0.0000000 241 9028 208 0.0230394 0.8630705 GO:0033044 GO:BP regulation of chromosome organization 16307 8469 GO:00330…. query_1 TRUE 0.0000000 554 9028 422 0.0467435 0.7617329 GO:0051276 GO:BP chromosome organization 16307 14465 GO:0006996 query_1 TRUE 0.0000000 285 9028 239 0.0264732 0.8385965 GO:0000398 GO:BP mRNA splicing, via spliceosome 16307 129 GO:00003…. query_1 TRUE 0.0000000 285 9028 239 0.0264732 0.8385965 GO:0000377 GO:BP RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 16307 117 GO:0000375 query_1 TRUE 0.0000000 2342 9028 1521 0.1684759 0.6494449 GO:0006796 GO:BP phosphate-containing compound metabolic process 16307 2551 GO:0006793 query_1 TRUE 0.0000000 1527 9028 1027 0.1137572 0.6725606 GO:0043933 GO:BP protein-containing complex organization 16307 11528 GO:0016043 query_1 TRUE 0.0000000 794 9028 572 0.0633584 0.7204030 GO:0051248 GO:BP negative regulation of protein metabolic process 16307 14447 GO:00106…. query_1 TRUE 0.0000000 158 9028 144 0.0159504 0.9113924 GO:0140053 GO:BP mitochondrial gene expression 16307 20877 GO:0010467 query_1 TRUE 0.0000000 4394 9028 2709 0.3000665 0.6165225 GO:0048519 GO:BP negative regulation of biological process 16307 13623 GO:00081…. query_1 TRUE 0.0000000 4712 9028 2890 0.3201152 0.6133277 GO:0048522 GO:BP positive regulation of cellular process 16307 13626 GO:00099…. query_1 TRUE 0.0000000 482 9028 369 0.0408728 0.7655602 GO:0051640 GO:BP organelle localization 16307 14724 GO:0051179 query_1 TRUE 0.0000000 280 9028 232 0.0256978 0.8285714 GO:0006605 GO:BP protein targeting 16307 2389 GO:0006886 query_1 TRUE 0.0000000 3898 9028 2420 0.2680549 0.6208312 GO:0048523 GO:BP negative regulation of cellular process 16307 13627 GO:00099…. query_1 TRUE 0.0000000 231 9028 196 0.0217102 0.8484848 GO:0034504 GO:BP protein localization to nucleus 16307 9175 GO:0033365 query_1 TRUE 0.0000000 288 9028 236 0.0261409 0.8194444 GO:0048193 GO:BP Golgi vesicle transport 16307 13388 GO:0016192 query_1 TRUE 0.0000000 260 9028 216 0.0239256 0.8307692 GO:0006913 GO:BP nucleocytoplasmic transport 16307 2634 GO:0051169 query_1 TRUE 0.0000000 260 9028 216 0.0239256 0.8307692 GO:0051169 GO:BP nuclear transport 16307 14397 GO:0046907 query_1 TRUE 0.0000000 376 9028 295 0.0326761 0.7845745 GO:0007059 GO:BP chromosome segregation 16307 2733 GO:0022402 query_1 TRUE 0.0000000 268 9028 221 0.0244794 0.8246269 GO:0140014 GO:BP mitotic nuclear division 16307 20857 GO:00002…. query_1 TRUE 0.0000000 202 9028 174 0.0192734 0.8613861 GO:0071826 GO:BP ribonucleoprotein complex subunit organization 16307 18015 GO:0043933 query_1 TRUE 0.0000000 236 9028 198 0.0219318 0.8389831 GO:0000819 GO:BP sister chromatid segregation 16307 253 GO:00512…. query_1 TRUE 0.0000000 147 9028 133 0.0147319 0.9047619 GO:0006261 GO:BP DNA-templated DNA replication 16307 2136 GO:0006260 query_1 TRUE 0.0000000 130 9028 120 0.0132920 0.9230769 GO:0032543 GO:BP mitochondrial translation 16307 8100 GO:00064…. query_1 TRUE 0.0000000 4286 9028 2630 0.2913159 0.6136258 GO:0010468 GO:BP regulation of gene expression 16307 4271 GO:00104…. query_1 TRUE 0.0000000 3212 9028 2010 0.2226407 0.6257783 GO:0032774 GO:BP RNA biosynthetic process 16307 8281 GO:00090…. query_1 TRUE 0.0000000 194 9028 167 0.0184980 0.8608247 GO:0022618 GO:BP ribonucleoprotein complex assembly 16307 7022 GO:00226…. query_1 TRUE 0.0000000 1257 9028 849 0.0940408 0.6754177 GO:0010558 GO:BP negative regulation of macromolecule biosynthetic process 16307 4328 GO:00090…. query_1 TRUE 0.0000000 457 9028 346 0.0383252 0.7571116 GO:0009896 GO:BP positive regulation of catabolic process 16307 3850 GO:00090…. query_1 TRUE 0.0000000 1297 9028 872 0.0965884 0.6723207 GO:0031327 GO:BP negative regulation of cellular biosynthetic process 16307 7553 GO:00098…. query_1 TRUE 0.0000000 3177 9028 1984 0.2197607 0.6244885 GO:0097659 GO:BP nucleic acid-templated transcription 16307 19903 GO:00104…. query_1 TRUE 0.0000000 1321 9028 885 0.0980284 0.6699470 GO:0009890 GO:BP negative regulation of biosynthetic process 16307 3844 GO:00090…. query_1 TRUE 0.0000000 231 9028 192 0.0212672 0.8311688 GO:0034976 GO:BP response to endoplasmic reticulum stress 16307 9268 GO:0033554 query_1 TRUE 0.0000000 193 9028 165 0.0182765 0.8549223 GO:0000070 GO:BP mitotic sister chromatid segregation 16307 25 GO:00008…. query_1 TRUE 0.0000000 3173 9028 1980 0.2193177 0.6240151 GO:0006351 GO:BP DNA-templated transcription 16307 2189 GO:0097659 query_1 TRUE 0.0000000 156 9028 138 0.0152858 0.8846154 GO:0002181 GO:BP cytoplasmic translation 16307 753 GO:0006412 query_1 TRUE 0.0000000 227 9028 189 0.0209349 0.8325991 GO:0043543 GO:BP protein acylation 16307 11413 GO:0036211 query_1 TRUE 0.0000000 365 9028 283 0.0313469 0.7753425 GO:0034655 GO:BP nucleobase-containing compound catabolic process 16307 9219 GO:00061…. query_1 TRUE 0.0000000 1758 9028 1146 0.1269384 0.6518771 GO:0071702 GO:BP organic substance transport 16307 17951 GO:0006810 query_1 TRUE 0.0000000 379 9028 292 0.0323438 0.7704485 GO:0031331 GO:BP positive regulation of cellular catabolic process 16307 7557 GO:00098…. query_1 TRUE 0.0000000 373 9028 288 0.0319008 0.7721180 GO:0051656 GO:BP establishment of organelle localization 16307 14740 GO:00512…. query_1 TRUE 0.0000000 261 9028 212 0.0234825 0.8122605 GO:0010948 GO:BP negative regulation of cell cycle process 16307 4668 GO:00105…. query_1 TRUE 0.0000000 113 9028 105 0.0116305 0.9292035 GO:0006354 GO:BP DNA-templated transcription elongation 16307 2192 GO:00063…. query_1 TRUE 0.0000000 172 9028 149 0.0165042 0.8662791 GO:0000075 GO:BP cell cycle checkpoint signaling 16307 27 GO:00355…. query_1 TRUE 0.0000000 1397 9028 928 0.1027913 0.6642806 GO:0012501 GO:BP programmed cell death 16307 4716 GO:0008219 query_1 TRUE 0.0000000 332 9028 260 0.0287993 0.7831325 GO:0018205 GO:BP peptidyl-lysine modification 16307 5601 GO:0018193 query_1 TRUE 0.0000000 1356 9028 902 0.0999114 0.6651917 GO:0065003 GO:BP protein-containing complex assembly 16307 16924 GO:00226…. query_1 TRUE 0.0000000 309 9028 244 0.0270270 0.7896440 GO:0010506 GO:BP regulation of autophagy 16307 4291 GO:00069…. query_1 TRUE 0.0000000 283 9028 226 0.0250332 0.7985866 GO:2001020 GO:BP regulation of response to DNA damage stimulus 16307 27714 GO:00069…. query_1 TRUE 0.0000000 221 9028 183 0.0202703 0.8280543 GO:1901988 GO:BP negative regulation of cell cycle phase transition 16307 23056 GO:00109…. query_1 TRUE 0.0000000 2197 9028 1402 0.1552946 0.6381429 GO:0035556 GO:BP intracellular signal transduction 16307 9639 GO:0007165 query_1 TRUE 0.0000000 96 9028 91 0.0100798 0.9479167 GO:0006368 GO:BP transcription elongation by RNA polymerase II 16307 2204 GO:00063…. query_1 TRUE 0.0000000 343 9028 266 0.0294639 0.7755102 GO:0016032 GO:BP viral process 16307 5227 GO:0008150 query_1 TRUE 0.0000000 142 9028 126 0.0139566 0.8873239 GO:0016573 GO:BP histone acetylation 16307 5417 GO:00165…. query_1 TRUE 0.0000000 333 9028 259 0.0286885 0.7777778 GO:0045786 GO:BP negative regulation of cell cycle 16307 12392 GO:00070…. query_1 TRUE 0.0000000 1342 9028 891 0.0986930 0.6639344 GO:0006915 GO:BP apoptotic process 16307 2636 GO:0012501 query_1 TRUE 0.0000000 1538 9028 1009 0.1117634 0.6560468 GO:0008219 GO:BP cell death 16307 3234 GO:0009987 query_1 TRUE 0.0000000 153 9028 134 0.0148427 0.8758170 GO:0018394 GO:BP peptidyl-lysine acetylation 16307 5721 GO:00064…. query_1 TRUE 0.0000000 145 9028 128 0.0141781 0.8827586 GO:0018393 GO:BP internal peptidyl-lysine acetylation 16307 5720 GO:00064…. query_1 TRUE 0.0000000 235 9028 192 0.0212672 0.8170213 GO:0097193 GO:BP intrinsic apoptotic signaling pathway 16307 19706 GO:00355…. query_1 TRUE 0.0000000 933 9028 640 0.0708906 0.6859593 GO:1901135 GO:BP carbohydrate derivative metabolic process 16307 22307 GO:0071704 query_1 TRUE 0.0000000 951 9028 651 0.0721090 0.6845426 GO:0045944 GO:BP positive regulation of transcription by RNA polymerase II 16307 12513 GO:00063…. query_1 TRUE 0.0000000 456 9028 339 0.0375498 0.7434211 GO:0097190 GO:BP apoptotic signaling pathway 16307 19703 GO:00069…. query_1 TRUE 0.0000000 3088 9028 1919 0.2125609 0.6214378 GO:2001141 GO:BP regulation of RNA biosynthetic process 16307 27809 GO:00105…. query_1 TRUE 0.0000000 147 9028 129 0.0142889 0.8775510 GO:0006475 GO:BP internal protein amino acid acetylation 16307 2276 GO:0006473 query_1 TRUE 0.0000000 290 9028 229 0.0253655 0.7896552 GO:0006302 GO:BP double-strand break repair 16307 2167 GO:0006281 query_1 TRUE 0.0000000 265 9028 212 0.0234825 0.8000000 GO:0006401 GO:BP RNA catabolic process 16307 2225 GO:00160…. query_1 TRUE 0.0000000 233 9028 190 0.0210456 0.8154506 GO:0000209 GO:BP protein polyubiquitination 16307 63 GO:0016567 query_1 TRUE 0.0000000 186 9028 157 0.0173903 0.8440860 GO:0006473 GO:BP protein acetylation 16307 2274 GO:0043543 query_1 TRUE 0.0000000 1249 9028 832 0.0921577 0.6661329 GO:0031399 GO:BP regulation of protein modification process 16307 7591 GO:00362…. query_1 TRUE 0.0000000 3065 9028 1904 0.2108994 0.6212072 GO:1903506 GO:BP regulation of nucleic acid-templated transcription 16307 24286 GO:00976…. query_1 TRUE 0.0000000 765 9028 534 0.0591493 0.6980392 GO:0060341 GO:BP regulation of cellular localization 16307 15480 GO:00328…. query_1 TRUE 0.0000000 5329 9028 3197 0.3541205 0.5999249 GO:0048518 GO:BP positive regulation of biological process 16307 13622 GO:00081…. query_1 TRUE 0.0000000 3060 9028 1899 0.2103456 0.6205882 GO:0006355 GO:BP regulation of DNA-templated transcription 16307 2193 GO:00063…. query_1 TRUE 0.0000000 671 9028 474 0.0525033 0.7064083 GO:0032880 GO:BP regulation of protein localization 16307 8345 GO:00081…. query_1 TRUE 0.0000000 3185 9028 1969 0.2180992 0.6182104 GO:0006950 GO:BP response to stress 16307 2656 GO:0050896 query_1 TRUE 0.0000000 402 9028 301 0.0333407 0.7487562 GO:0044270 GO:BP cellular nitrogen compound catabolic process 16307 11655 GO:00346…. query_1 TRUE 0.0000000 194 9028 161 0.0178334 0.8298969 GO:0000082 GO:BP G1/S transition of mitotic cell cycle 16307 32 GO:00447…. query_1 TRUE 0.0000000 398 9028 298 0.0330084 0.7487437 GO:0046700 GO:BP heterocycle catabolic process 16307 13113 GO:00442…. query_1 TRUE 0.0000000 257 9028 204 0.0225964 0.7937743 GO:0051054 GO:BP positive regulation of DNA metabolic process 16307 14307 GO:00062…. query_1 TRUE 0.0000000 158 9028 135 0.0149535 0.8544304 GO:0071897 GO:BP DNA biosynthetic process 16307 18061 GO:00062…. query_1 TRUE 0.0000000 96 9028 89 0.0098582 0.9270833 GO:0032784 GO:BP regulation of DNA-templated transcription elongation 16307 8287 GO:00063…. query_1 TRUE 0.0000000 1006 9028 678 0.0750997 0.6739563 GO:0018193 GO:BP peptidyl-amino acid modification 16307 5590 GO:0036211 query_1 TRUE 0.0000000 146 9028 126 0.0139566 0.8630137 GO:0006403 GO:BP RNA localization 16307 2227 GO:0033036 query_1 TRUE 0.0000000 414 9028 307 0.0340053 0.7415459 GO:0019439 GO:BP aromatic compound catabolic process 16307 6133 GO:00067…. query_1 TRUE 0.0000000 517 9028 373 0.0413159 0.7214700 GO:0090407 GO:BP organophosphate biosynthetic process 16307 19433 GO:00196…. query_1 TRUE 0.0000000 166 9028 140 0.0155073 0.8433735 GO:0042770 GO:BP signal transduction in response to DNA damage 16307 10987 GO:00069…. query_1 TRUE 0.0000000 401 9028 298 0.0330084 0.7431421 GO:0031400 GO:BP negative regulation of protein modification process 16307 7592 GO:00313…. query_1 TRUE 0.0000000 80 9028 76 0.0084183 0.9500000 GO:0034243 GO:BP regulation of transcription elongation by RNA polymerase II 16307 9013 GO:00063…. query_1 TRUE 0.0000000 1280 9028 842 0.0932654 0.6578125 GO:0045934 GO:BP negative regulation of nucleobase-containing compound metabolic process 16307 12504 GO:00061…. query_1 TRUE 0.0000000 295 9028 228 0.0252548 0.7728814 GO:0031647 GO:BP regulation of protein stability 16307 7700 GO:0065008 query_1 TRUE 0.0000000 1249 9028 823 0.0911608 0.6589271 GO:0051247 GO:BP positive regulation of protein metabolic process 16307 14446 GO:00106…. query_1 TRUE 0.0000000 439 9028 322 0.0356668 0.7334852 GO:0010638 GO:BP positive regulation of organelle organization 16307 4402 GO:00069…. query_1 TRUE 0.0000000 132 9028 115 0.0127381 0.8712121 GO:0007093 GO:BP mitotic cell cycle checkpoint signaling 16307 2755 GO:00000…. query_1 TRUE 0.0000000 1082 9028 721 0.0798626 0.6663586 GO:0043067 GO:BP regulation of programmed cell death 16307 11152 GO:00109…. query_1 TRUE 0.0000000 423 9028 311 0.0344484 0.7352246 GO:0022411 GO:BP cellular component disassembly 16307 6999 GO:0016043 query_1 TRUE 0.0000000 277 9028 215 0.0238148 0.7761733 GO:0032386 GO:BP regulation of intracellular transport 16307 8001 GO:00469…. query_1 TRUE 0.0000000 199 9028 162 0.0179442 0.8140704 GO:0045930 GO:BP negative regulation of mitotic cell cycle 16307 12500 GO:00002…. query_1 TRUE 0.0000000 1208 9028 796 0.0881701 0.6589404 GO:0010941 GO:BP regulation of cell death 16307 4663 GO:00082…. query_1 TRUE 0.0000000 725 9028 501 0.0554940 0.6910345 GO:0051338 GO:BP regulation of transferase activity 16307 14517 GO:0050790 query_1 TRUE 0.0000000 300 9028 230 0.0254763 0.7666667 GO:0042176 GO:BP regulation of protein catabolic process 16307 10631 GO:00098…. query_1 TRUE 0.0000000 151 9028 128 0.0141781 0.8476821 GO:0051168 GO:BP nuclear export 16307 14396 GO:0006913 query_1 TRUE 0.0000000 188 9028 154 0.0170580 0.8191489 GO:0007033 GO:BP vacuole organization 16307 2713 GO:0006996 query_1 TRUE 0.0000000 223 9028 178 0.0197164 0.7982063 GO:0044843 GO:BP cell cycle G1/S phase transition 16307 11951 GO:0044770 query_1 TRUE 0.0000000 174 9028 144 0.0159504 0.8275862 GO:0007051 GO:BP spindle organization 16307 2725 GO:00002…. query_1 TRUE 0.0000000 177 9028 146 0.0161719 0.8248588 GO:0006399 GO:BP tRNA metabolic process 16307 2223 GO:0034660 query_1 TRUE 0.0000000 209 9028 168 0.0186088 0.8038278 GO:1903320 GO:BP regulation of protein modification by small protein conjugation or removal 16307 24123 GO:00313…. query_1 TRUE 0.0000000 582 9028 410 0.0454143 0.7044674 GO:0051668 GO:BP localization within membrane 16307 14751 GO:0051641 query_1 TRUE 0.0000000 1057 9028 702 0.0777581 0.6641438 GO:0042981 GO:BP regulation of apoptotic process 16307 11103 GO:00069…. query_1 TRUE 0.0000000 179 9028 147 0.0162827 0.8212291 GO:0034249 GO:BP negative regulation of amide metabolic process 16307 9017 GO:00342…. query_1 TRUE 0.0000000 152 9028 128 0.0141781 0.8421053 GO:1902850 GO:BP microtubule cytoskeleton organization involved in mitosis 16307 23739 GO:00002…. query_1 TRUE 0.0000000 162 9028 135 0.0149535 0.8333333 GO:0009451 GO:BP RNA modification 16307 3591 GO:00160…. query_1 TRUE 0.0000000 278 9028 214 0.0237040 0.7697842 GO:1903311 GO:BP regulation of mRNA metabolic process 16307 24114 GO:00160…. query_1 TRUE 0.0000000 220 9028 175 0.0193841 0.7954545 GO:0006402 GO:BP mRNA catabolic process 16307 2226 GO:00064…. query_1 TRUE 0.0000000 226 9028 179 0.0198272 0.7920354 GO:0008654 GO:BP phospholipid biosynthetic process 16307 3317 GO:00066…. query_1 TRUE 0.0000000 435 9028 316 0.0350022 0.7264368 GO:1901361 GO:BP organic cyclic compound catabolic process 16307 22498 GO:19013…. query_1 TRUE 0.0000000 115 9028 101 0.0111874 0.8782609 GO:0051983 GO:BP regulation of chromosome segregation 16307 14922 GO:00070…. query_1 TRUE 0.0000000 174 9028 143 0.0158396 0.8218391 GO:2000113 GO:BP negative regulation of cellular macromolecule biosynthetic process 16307 26872 GO:00105…. query_1 TRUE 0.0000000 822 9028 557 0.0616969 0.6776156 GO:0070925 GO:BP organelle assembly 16307 17435 GO:00069…. query_1 TRUE 0.0000000 118 9028 103 0.0114089 0.8728814 GO:0008033 GO:BP tRNA processing 16307 3186 GO:00063…. query_1 TRUE 0.0000000 1165 9028 765 0.0847364 0.6566524 GO:0051253 GO:BP negative regulation of RNA metabolic process 16307 14452 GO:00106…. query_1 TRUE 0.0000000 139 9028 118 0.0130704 0.8489209 GO:0000723 GO:BP telomere maintenance 16307 216 GO:00062…. query_1 TRUE 0.0000000 156 9028 130 0.0143996 0.8333333 GO:1901991 GO:BP negative regulation of mitotic cell cycle phase transition 16307 23059 GO:00447…. query_1 TRUE 0.0000000 4385 9028 2634 0.2917590 0.6006842 GO:0051179 GO:BP localization 16307 14406 GO:0008150 query_1 TRUE 0.0000000 312 9028 235 0.0260301 0.7532051 GO:0016050 GO:BP vesicle organization 16307 5238 GO:0006996 query_1 TRUE 0.0000000 158 9028 131 0.0145104 0.8291139 GO:0017148 GO:BP negative regulation of translation 16307 5452 GO:00064…. query_1 TRUE 0.0000000 112 9028 98 0.0108551 0.8750000 GO:0006413 GO:BP translational initiation 16307 2235 GO:00064…. query_1 TRUE 0.0000000 119 9028 103 0.0114089 0.8655462 GO:0031570 GO:BP DNA integrity checkpoint signaling 16307 7662 GO:0000075 query_1 TRUE 0.0000000 157 9028 130 0.0143996 0.8280255 GO:0006839 GO:BP mitochondrial transport 16307 2578 GO:0046907 query_1 TRUE 0.0000000 183 9028 148 0.0163934 0.8087432 GO:0033157 GO:BP regulation of intracellular protein transport 16307 8537 GO:00068…. query_1 TRUE 0.0000000 118 9028 102 0.0112982 0.8644068 GO:0006275 GO:BP regulation of DNA replication 16307 2148 GO:00062…. query_1 TRUE 0.0000000 297 9028 224 0.0248117 0.7542088 GO:0098813 GO:BP nuclear chromosome segregation 16307 20093 GO:0007059 query_1 TRUE 0.0000000 99 9028 88 0.0097475 0.8888889 GO:0033045 GO:BP regulation of sister chromatid segregation 16307 8470 GO:00008…. query_1 TRUE 0.0000000 551 9028 386 0.0427559 0.7005445 GO:0030162 GO:BP regulation of proteolysis 16307 7089 GO:00065…. query_1 TRUE 0.0000000 74 9028 69 0.0076429 0.9324324 GO:0042273 GO:BP ribosomal large subunit biogenesis 16307 10698 GO:00226…. query_1 TRUE 0.0000000 145 9028 121 0.0134027 0.8344828 GO:0007034 GO:BP vacuolar transport 16307 2714 GO:0046907 query_1 TRUE 0.0000000 138 9028 116 0.0128489 0.8405797 GO:2000045 GO:BP regulation of G1/S transition of mitotic cell cycle 16307 26806 GO:00000…. query_1 TRUE 0.0000000 571 9028 398 0.0440851 0.6970228 GO:1901137 GO:BP carbohydrate derivative biosynthetic process 16307 22309 GO:19011…. query_1 TRUE 0.0000000 1443 9028 926 0.1025698 0.6417186 GO:0016310 GO:BP phosphorylation 16307 5357 GO:0006796 query_1 TRUE 0.0000000 127 9028 108 0.0119628 0.8503937 GO:1903008 GO:BP organelle disassembly 16307 23879 GO:00069…. query_1 TRUE 0.0000000 332 9028 246 0.0272486 0.7409639 GO:0140694 GO:BP non-membrane-bounded organelle assembly 16307 21093 GO:0070925 query_1 TRUE 0.0000000 226 9028 176 0.0194949 0.7787611 GO:0051348 GO:BP negative regulation of transferase activity 16307 14527 GO:00430…. query_1 TRUE 0.0000000 247 9028 190 0.0210456 0.7692308 GO:0062197 GO:BP cellular response to chemical stress 16307 16898 GO:00335…. query_1 TRUE 0.0000000 198 9028 157 0.0173903 0.7929293 GO:1903050 GO:BP regulation of proteolysis involved in protein catabolic process 16307 23919 GO:00301…. query_1 TRUE 0.0000000 811 9028 545 0.0603677 0.6720099 GO:0010629 GO:BP negative regulation of gene expression 16307 4393 GO:00104…. query_1 TRUE 0.0000000 89 9028 80 0.0088613 0.8988764 GO:0007091 GO:BP metaphase/anaphase transition of mitotic cell cycle 16307 2754 GO:00447…. query_1 TRUE 0.0000000 63 9028 60 0.0066460 0.9523810 GO:0071103 GO:BP DNA conformation change 16307 17522 GO:0051276 query_1 TRUE 0.0000000 104 9028 91 0.0100798 0.8750000 GO:1905037 GO:BP autophagosome organization 16307 25635 GO:00070…. query_1 TRUE 0.0000000 1213 9028 787 0.0871732 0.6488046 GO:0080134 GO:BP regulation of response to stress 16307 18942 GO:00069…. query_1 TRUE 0.0000000 1437 9028 920 0.1019052 0.6402227 GO:1902531 GO:BP regulation of intracellular signal transduction 16307 23502 GO:00099…. query_1 TRUE 0.0000000 125 9028 106 0.0117412 0.8480000 GO:0035966 GO:BP response to topologically incorrect protein 16307 9928 GO:00069…. query_1 TRUE 0.0000000 1052 9028 690 0.0764289 0.6558935 GO:1903507 GO:BP negative regulation of nucleic acid-templated transcription 16307 24287 GO:00976…. query_1 TRUE 0.0000000 885 9028 589 0.0652415 0.6655367 GO:0019637 GO:BP organophosphate metabolic process 16307 6315 GO:00067…. query_1 TRUE 0.0000000 99 9028 87 0.0096367 0.8787879 GO:0019080 GO:BP viral gene expression 16307 5899 GO:0016032 query_1 TRUE 0.0000000 235 9028 181 0.0200487 0.7702128 GO:0016197 GO:BP endosomal transport 16307 5326 GO:00161…. query_1 TRUE 0.0000000 403 9028 290 0.0321223 0.7196030 GO:0006325 GO:BP chromatin organization 16307 2182 GO:0016043 query_1 TRUE 0.0000000 367 9028 267 0.0295747 0.7275204 GO:1903829 GO:BP positive regulation of protein localization 16307 24571 GO:00081…. query_1 TRUE 0.0000000 1047 9028 686 0.0759858 0.6552053 GO:0045892 GO:BP negative regulation of DNA-templated transcription 16307 12466 GO:00063…. query_1 TRUE 0.0000000 273 9028 206 0.0228179 0.7545788 GO:0043414 GO:BP macromolecule methylation 16307 11328 GO:00322…. query_1 TRUE 0.0000000 91 9028 81 0.0089721 0.8901099 GO:0044784 GO:BP metaphase/anaphase transition of cell cycle 16307 11915 GO:00330…. query_1 TRUE 0.0000000 492 9028 346 0.0383252 0.7032520 GO:0072657 GO:BP protein localization to membrane 16307 18584 GO:00081…. query_1 TRUE 0.0000000 1514 9028 964 0.1067789 0.6367239 GO:0050790 GO:BP regulation of catalytic activity 16307 14088 GO:0065009 query_1 TRUE 0.0000000 341 9028 250 0.0276916 0.7331378 GO:0010563 GO:BP negative regulation of phosphorus metabolic process 16307 4333 GO:00067…. query_1 TRUE 0.0000000 1534 9028 975 0.1079973 0.6355932 GO:0044281 GO:BP small molecule metabolic process 16307 11662 GO:0008152 query_1 TRUE 0.0000000 340 9028 249 0.0275809 0.7323529 GO:0045936 GO:BP negative regulation of phosphate metabolic process 16307 12506 GO:00067…. query_1 TRUE 0.0000000 197 9028 155 0.0171688 0.7868020 GO:0006282 GO:BP regulation of DNA repair 16307 2154 GO:00062…. query_1 TRUE 0.0000000 172 9028 138 0.0152858 0.8023256 GO:0031396 GO:BP regulation of protein ubiquitination 16307 7588 GO:00165…. query_1 TRUE 0.0000000 86 9028 77 0.0085290 0.8953488 GO:0030071 GO:BP regulation of mitotic metaphase/anaphase transition 16307 7069 GO:00070…. query_1 TRUE 0.0000000 86 9028 77 0.0085290 0.8953488 GO:0006400 GO:BP tRNA modification 16307 2224 GO:00080…. query_1 TRUE 0.0000000 233 9028 179 0.0198272 0.7682403 GO:0090150 GO:BP establishment of protein localization to membrane 16307 19203 GO:00451…. query_1 TRUE 0.0000000 146 9028 120 0.0132920 0.8219178 GO:0072331 GO:BP signal transduction by p53 class mediator 16307 18456 GO:0035556 query_1 TRUE 0.0000000 146 9028 120 0.0132920 0.8219178 GO:0016241 GO:BP regulation of macroautophagy 16307 5340 GO:00105…. query_1 TRUE 0.0000000 777 9028 521 0.0577093 0.6705277 GO:0044087 GO:BP regulation of cellular component biogenesis 16307 11607 GO:00440…. query_1 TRUE 0.0000000 1065 9028 695 0.0769827 0.6525822 GO:1902679 GO:BP negative regulation of RNA biosynthetic process 16307 23602 GO:00105…. query_1 TRUE 0.0000000 316 9028 233 0.0258086 0.7373418 GO:0045862 GO:BP positive regulation of proteolysis 16307 12450 GO:00065…. query_1 TRUE 0.0000000 171 9028 137 0.0151750 0.8011696 GO:0032388 GO:BP positive regulation of intracellular transport 16307 8003 GO:00323…. query_1 TRUE 0.0000000 125 9028 105 0.0116305 0.8400000 GO:0007052 GO:BP mitotic spindle organization 16307 2726 GO:00070…. query_1 TRUE 0.0000000 111 9028 95 0.0105228 0.8558559 GO:0000077 GO:BP DNA damage checkpoint signaling 16307 29 GO:00315…. query_1 TRUE 0.0000000 100 9028 87 0.0096367 0.8700000 GO:0000045 GO:BP autophagosome assembly 16307 18 GO:00709…. query_1 TRUE 0.0000000 131 9028 109 0.0120735 0.8320611 GO:0090316 GO:BP positive regulation of intracellular protein transport 16307 19354 GO:00068…. query_1 TRUE 0.0000000 68 9028 63 0.0069783 0.9264706 GO:0051310 GO:BP metaphase plate congression 16307 14493 GO:00513…. query_1 TRUE 0.0000000 68 9028 63 0.0069783 0.9264706 GO:0042274 GO:BP ribosomal small subunit biogenesis 16307 10699 GO:00226…. query_1 TRUE 0.0000000 516 9028 359 0.0397652 0.6957364 GO:0010256 GO:BP endomembrane system organization 16307 4131 GO:0016043 query_1 TRUE 0.0000000 88 9028 78 0.0086398 0.8863636 GO:1902099 GO:BP regulation of metaphase/anaphase transition of cell cycle 16307 23153 GO:00330…. query_1 TRUE 0.0000000 200 9028 156 0.0172796 0.7800000 GO:0050821 GO:BP protein stabilization 16307 14112 GO:0031647 query_1 TRUE 0.0000000 150 9028 122 0.0135135 0.8133333 GO:0042594 GO:BP response to starvation 16307 10885 GO:00069…. query_1 TRUE 0.0000000 102 9028 88 0.0097475 0.8627451 GO:0035967 GO:BP cellular response to topologically incorrect protein 16307 9929 GO:00335…. query_1 TRUE 0.0000000 133 9028 110 0.0121843 0.8270677 GO:0009267 GO:BP cellular response to starvation 16307 3524 GO:00316…. query_1 TRUE 0.0000000 284 9028 211 0.0233717 0.7429577 GO:0032259 GO:BP methylation 16307 7906 GO:0008152 query_1 TRUE 0.0000000 168 9028 134 0.0148427 0.7976190 GO:0000725 GO:BP recombinational repair 16307 218 GO:00062…. query_1 TRUE 0.0000000 174 9028 138 0.0152858 0.7931034 GO:0051650 GO:BP establishment of vesicle localization 16307 14734 GO:00516…. query_1 TRUE 0.0000000 78 9028 70 0.0077537 0.8974359 GO:0001510 GO:BP RNA methylation 16307 345 GO:00094…. query_1 TRUE 0.0000000 227 9028 173 0.0191626 0.7621145 GO:0071496 GO:BP cellular response to external stimulus 16307 17805 GO:0009605 query_1 TRUE 0.0000000 2141 9028 1324 0.1466549 0.6184026 GO:0065009 GO:BP regulation of molecular function 16307 16929 GO:0065007 query_1 TRUE 0.0000000 100 9028 86 0.0095259 0.8600000 GO:0006892 GO:BP post-Golgi vesicle-mediated transport 16307 2619 GO:0048193 query_1 TRUE 0.0000000 147 9028 119 0.0131812 0.8095238 GO:2000058 GO:BP regulation of ubiquitin-dependent protein catabolic process 16307 26818 GO:00065…. query_1 TRUE 0.0000000 96 9028 83 0.0091936 0.8645833 GO:0045931 GO:BP positive regulation of mitotic cell cycle 16307 12501 GO:00002…. query_1 TRUE 0.0000000 110 9028 93 0.0103013 0.8454545 GO:2000278 GO:BP regulation of DNA biosynthetic process 16307 27031 GO:00105…. query_1 TRUE 0.0000000 81 9028 72 0.0079752 0.8888889 GO:0000422 GO:BP autophagy of mitochondrion 16307 137 GO:00069…. query_1 TRUE 0.0000000 81 9028 72 0.0079752 0.8888889 GO:0061726 GO:BP mitochondrion disassembly 16307 16661 GO:00070…. query_1 TRUE 0.0000000 143 9028 116 0.0128489 0.8111888 GO:0031023 GO:BP microtubule organizing center organization 16307 7405 GO:00002…. query_1 TRUE 0.0000000 165 9028 131 0.0145104 0.7939394 GO:0000724 GO:BP double-strand break repair via homologous recombination 16307 217 GO:00007…. query_1 TRUE 0.0000000 165 9028 131 0.0145104 0.7939394 GO:1902806 GO:BP regulation of cell cycle G1/S phase transition 16307 23700 GO:00448…. query_1 TRUE 0.0000000 231 9028 175 0.0193841 0.7575758 GO:0045017 GO:BP glycerolipid biosynthetic process 16307 11994 GO:00086…. query_1 TRUE 0.0000000 288 9028 212 0.0234825 0.7361111 GO:0006979 GO:BP response to oxidative stress 16307 2678 GO:0006950 query_1 TRUE 0.0000000 401 9028 284 0.0314577 0.7082294 GO:0070201 GO:BP regulation of establishment of protein localization 16307 17025 GO:00328…. query_1 TRUE 0.0000000 129 9028 106 0.0117412 0.8217054 GO:0007098 GO:BP centrosome cycle 16307 2760 GO:00224…. query_1 TRUE 0.0000000 55 9028 52 0.0057599 0.9454545 GO:0032392 GO:BP DNA geometric change 16307 8004 GO:0071103 query_1 TRUE 0.0000000 844 9028 556 0.0615862 0.6587678 GO:0051130 GO:BP positive regulation of cellular component organization 16307 14359 GO:00160…. query_1 TRUE 0.0000000 170 9028 134 0.0148427 0.7882353 GO:0043484 GO:BP regulation of RNA splicing 16307 11381 GO:00083…. query_1 TRUE 0.0000000 170 9028 134 0.0148427 0.7882353 GO:0031669 GO:BP cellular response to nutrient levels 16307 7716 GO:00316…. query_1 TRUE 0.0000000 170 9028 134 0.0148427 0.7882353 GO:0061136 GO:BP regulation of proteasomal protein catabolic process 16307 16216 GO:00104…. query_1 TRUE 0.0000000 112 9028 94 0.0104121 0.8392857 GO:0072655 GO:BP establishment of protein localization to mitochondrion 16307 18582 GO:00705…. query_1 TRUE 0.0000000 122 9028 101 0.0111874 0.8278689 GO:0006661 GO:BP phosphatidylinositol biosynthetic process 16307 2437 GO:00464…. query_1 TRUE 0.0000000 206 9028 158 0.0175011 0.7669903 GO:0034599 GO:BP cellular response to oxidative stress 16307 9189 GO:00069…. query_1 TRUE 0.0000000 197 9028 152 0.0168365 0.7715736 GO:0046474 GO:BP glycerophospholipid biosynthetic process 16307 12967 GO:00066…. query_1 TRUE 0.0000000 108 9028 91 0.0100798 0.8425926 GO:0036503 GO:BP ERAD pathway 16307 10226 GO:00102…. query_1 TRUE 0.0000000 118 9028 98 0.0108551 0.8305085 GO:0000956 GO:BP nuclear-transcribed mRNA catabolic process 16307 281 GO:0006402 query_1 TRUE 0.0000000 181 9028 141 0.0156181 0.7790055 GO:0051648 GO:BP vesicle localization 16307 14732 GO:0051640 query_1 TRUE 0.0000000 505 9028 348 0.0385467 0.6891089 GO:0045859 GO:BP regulation of protein kinase activity 16307 12447 GO:00019…. query_1 TRUE 0.0000000 111 9028 93 0.0103013 0.8378378 GO:0051225 GO:BP spindle assembly 16307 14430 GO:00070…. query_1 TRUE 0.0000000 124 9028 102 0.0112982 0.8225806 GO:1903313 GO:BP positive regulation of mRNA metabolic process 16307 24116 GO:00160…. query_1 TRUE 0.0000000 171 9028 134 0.0148427 0.7836257 GO:0006469 GO:BP negative regulation of protein kinase activity 16307 2272 GO:00019…. query_1 TRUE 0.0000000 117 9028 97 0.0107444 0.8290598 GO:0070585 GO:BP protein localization to mitochondrion 16307 17244 GO:0033365 query_1 TRUE 0.0000000 174 9028 136 0.0150642 0.7816092 GO:0043123 GO:BP positive regulation of I-kappaB kinase/NF-kappaB signaling 16307 11183 GO:00072…. query_1 TRUE 0.0000000 149 9028 119 0.0131812 0.7986577 GO:0034250 GO:BP positive regulation of amide metabolic process 16307 9018 GO:00342…. query_1 TRUE 0.0000000 62 9028 57 0.0063137 0.9193548 GO:0030968 GO:BP endoplasmic reticulum unfolded protein response 16307 7387 GO:00071…. query_1 TRUE 0.0000000 89 9028 77 0.0085290 0.8651685 GO:0032204 GO:BP regulation of telomere maintenance 16307 7857 GO:00007…. query_1 TRUE 0.0000000 576 9028 391 0.0433097 0.6788194 GO:0000226 GO:BP microtubule cytoskeleton organization 16307 65 GO:00070…. query_1 TRUE 0.0000000 70 9028 63 0.0069783 0.9000000 GO:0051304 GO:BP chromosome separation 16307 14487 GO:00070…. query_1 TRUE 0.0000000 306 9028 222 0.0245902 0.7254902 GO:0010639 GO:BP negative regulation of organelle organization 16307 4403 GO:00069…. query_1 TRUE 0.0000000 188 9028 145 0.0160611 0.7712766 GO:0033673 GO:BP negative regulation of kinase activity 16307 8830 GO:00423…. query_1 TRUE 0.0000000 182 9028 141 0.0156181 0.7747253 GO:0031668 GO:BP cellular response to extracellular stimulus 16307 7715 GO:00071…. query_1 TRUE 0.0000000 77 9028 68 0.0075321 0.8831169 GO:0006446 GO:BP regulation of translational initiation 16307 2260 GO:00064…. query_1 TRUE 0.0000000 2486 9028 1516 0.1679220 0.6098150 GO:0009966 GO:BP regulation of signal transduction 16307 3898 GO:00071…. query_1 TRUE 0.0000000 381 9028 269 0.0297962 0.7060367 GO:0006091 GO:BP generation of precursor metabolites and energy 16307 2006 GO:0044237 query_1 TRUE 0.0000000 69 9028 62 0.0068675 0.8985507 GO:2000142 GO:BP regulation of DNA-templated transcription initiation 16307 26900 GO:00063…. query_1 TRUE 0.0000000 262 9028 193 0.0213779 0.7366412 GO:0045787 GO:BP positive regulation of cell cycle 16307 12393 GO:00070…. query_1 TRUE 0.0000000 128 9028 104 0.0115197 0.8125000 GO:0006888 GO:BP endoplasmic reticulum to Golgi vesicle-mediated transport 16307 2616 GO:00469…. query_1 TRUE 0.0000000 91 9028 78 0.0086398 0.8571429 GO:0010212 GO:BP response to ionizing radiation 16307 4091 GO:0009314 query_1 TRUE 0.0000000 47 9028 45 0.0049845 0.9574468 GO:0032968 GO:BP positive regulation of transcription elongation by RNA polymerase II 16307 8421 GO:00063…. query_1 TRUE 0.0000000 118 9028 97 0.0107444 0.8220339 GO:0007041 GO:BP lysosomal transport 16307 2720 GO:0007034 query_1 TRUE 0.0000000 56 9028 52 0.0057599 0.9285714 GO:0007080 GO:BP mitotic metaphase plate congression 16307 2748 GO:00000…. query_1 TRUE 0.0000000 56 9028 52 0.0057599 0.9285714 GO:0032786 GO:BP positive regulation of DNA-templated transcription, elongation 16307 8289 GO:00063…. query_1 TRUE 0.0000000 72 9028 64 0.0070891 0.8888889 GO:1901992 GO:BP positive regulation of mitotic cell cycle phase transition 16307 23060 GO:00447…. query_1 TRUE 0.0000000 241 9028 179 0.0198272 0.7427386 GO:0019058 GO:BP viral life cycle 16307 5883 GO:0016032 query_1 TRUE 0.0000000 371 9028 262 0.0290208 0.7061995 GO:0043065 GO:BP positive regulation of apoptotic process 16307 11150 GO:00069…. query_1 TRUE 0.0000000 258 9028 190 0.0210456 0.7364341 GO:0007249 GO:BP I-kappaB kinase/NF-kappaB signaling 16307 2868 GO:0035556 query_1 TRUE 0.0000000 68 9028 61 0.0067568 0.8970588 GO:0043966 GO:BP histone H3 acetylation 16307 11550 GO:0016573 query_1 TRUE 0.0000000 297 9028 215 0.0238148 0.7239057 GO:0042326 GO:BP negative regulation of phosphorylation 16307 10722 GO:00163…. query_1 TRUE 0.0000000 114 9028 94 0.0104121 0.8245614 GO:0051236 GO:BP establishment of RNA localization 16307 14438 GO:00064…. query_1 TRUE 0.0000000 97 9028 82 0.0090829 0.8453608 GO:0006626 GO:BP protein targeting to mitochondrion 16307 2407 GO:00066…. query_1 TRUE 0.0000000 2404 9028 1466 0.1623837 0.6098170 GO:0006366 GO:BP transcription by RNA polymerase II 16307 2202 GO:0006351 query_1 TRUE 0.0000000 167 9028 130 0.0143996 0.7784431 GO:0061013 GO:BP regulation of mRNA catabolic process 16307 16103 GO:00064…. query_1 TRUE 0.0000000 120 9028 98 0.0108551 0.8166667 GO:0051170 GO:BP import into nucleus 16307 14398 GO:0006913 query_1 TRUE 0.0000000 110 9028 91 0.0100798 0.8272727 GO:0098732 GO:BP macromolecule deacylation 16307 20047 GO:0043412 query_1 TRUE 0.0000000 110 9028 91 0.0100798 0.8272727 GO:0035601 GO:BP protein deacylation 16307 9664 GO:00362…. query_1 TRUE 0.0000000 93 9028 79 0.0087506 0.8494624 GO:2001252 GO:BP positive regulation of chromosome organization 16307 27899 GO:00106…. query_1 TRUE 0.0000000 600 9028 403 0.0446389 0.6716667 GO:0043549 GO:BP regulation of kinase activity 16307 11416 GO:00423…. query_1 TRUE 0.0000000 82 9028 71 0.0078644 0.8658537 GO:0000281 GO:BP mitotic cytokinesis 16307 83 GO:00616…. query_1 TRUE 0.0000000 1268 9028 803 0.0889455 0.6332808 GO:0006468 GO:BP protein phosphorylation 16307 2271 GO:00163…. query_1 TRUE 0.0000000 67 9028 60 0.0066460 0.8955224 GO:2000573 GO:BP positive regulation of DNA biosynthetic process 16307 27304 GO:00105…. query_1 TRUE 0.0000000 385 9028 270 0.0299070 0.7012987 GO:0043068 GO:BP positive regulation of programmed cell death 16307 11153 GO:00109…. query_1 TRUE 0.0000000 63 9028 57 0.0063137 0.9047619 GO:0070936 GO:BP protein K48-linked ubiquitination 16307 17445 GO:0000209 query_1 TRUE 0.0000000 96 9028 81 0.0089721 0.8437500 GO:1900180 GO:BP regulation of protein localization to nucleus 16307 21488 GO:00328…. query_1 TRUE 0.0000000 163 9028 127 0.0140673 0.7791411 GO:0043487 GO:BP regulation of RNA stability 16307 11383 GO:00064…. query_1 TRUE 0.0000000 172 9028 133 0.0147319 0.7732558 GO:1902115 GO:BP regulation of organelle assembly 16307 23169 GO:00330…. query_1 TRUE 0.0000000 132 9028 106 0.0117412 0.8030303 GO:0010508 GO:BP positive regulation of autophagy 16307 4293 GO:00069…. query_1 TRUE 0.0000000 78 9028 68 0.0075321 0.8717949 GO:0006289 GO:BP nucleotide-excision repair 16307 2160 GO:0006281 query_1 TRUE 0.0000001 261 9028 191 0.0211564 0.7318008 GO:0001933 GO:BP negative regulation of protein phosphorylation 16307 569 GO:00019…. query_1 TRUE 0.0000001 85 9028 73 0.0080860 0.8588235 GO:0030433 GO:BP ubiquitin-dependent ERAD pathway 16307 7202 GO:00365…. query_1 TRUE 0.0000001 92 9028 78 0.0086398 0.8478261 GO:2001251 GO:BP negative regulation of chromosome organization 16307 27898 GO:00106…. query_1 TRUE 0.0000001 74 9028 65 0.0071998 0.8783784 GO:0051303 GO:BP establishment of chromosome localization 16307 14486 GO:00500…. query_1 TRUE 0.0000001 70 9028 62 0.0068675 0.8857143 GO:0072665 GO:BP protein localization to vacuole 16307 18591 GO:0033365 query_1 TRUE 0.0000001 70 9028 62 0.0068675 0.8857143 GO:0006278 GO:BP RNA-templated DNA biosynthetic process 16307 2151 GO:0071897 query_1 TRUE 0.0000001 70 9028 62 0.0068675 0.8857143 GO:0007004 GO:BP telomere maintenance via telomerase 16307 2691 GO:00062…. query_1 TRUE 0.0000001 212 9028 159 0.0176119 0.7500000 GO:0032984 GO:BP protein-containing complex disassembly 16307 8433 GO:00224…. query_1 TRUE 0.0000001 115 9028 94 0.0104121 0.8173913 GO:0006606 GO:BP protein import into nucleus 16307 2390 GO:00068…. query_1 TRUE 0.0000001 62 9028 56 0.0062029 0.9032258 GO:0060260 GO:BP regulation of transcription initiation by RNA polymerase II 16307 15404 GO:00063…. query_1 TRUE 0.0000001 860 9028 559 0.0619185 0.6500000 GO:0044255 GO:BP cellular lipid metabolic process 16307 11647 GO:00066…. query_1 TRUE 0.0000001 620 9028 414 0.0458573 0.6677419 GO:0008610 GO:BP lipid biosynthetic process 16307 3297 GO:00066…. query_1 TRUE 0.0000001 433 9028 299 0.0331192 0.6905312 GO:1902532 GO:BP negative regulation of intracellular signal transduction 16307 23503 GO:00099…. query_1 TRUE 0.0000001 152 9028 119 0.0131812 0.7828947 GO:2001022 GO:BP positive regulation of response to DNA damage stimulus 16307 27716 GO:00069…. query_1 TRUE 0.0000001 111 9028 91 0.0100798 0.8198198 GO:0050658 GO:BP RNA transport 16307 14025 GO:00506…. query_1 TRUE 0.0000001 111 9028 91 0.0100798 0.8198198 GO:0050657 GO:BP nucleic acid transport 16307 14024 GO:0015931 query_1 TRUE 0.0000001 73 9028 64 0.0070891 0.8767123 GO:0006900 GO:BP vesicle budding from membrane 16307 2625 GO:00160…. query_1 TRUE 0.0000001 127 9028 102 0.0112982 0.8031496 GO:0031056 GO:BP regulation of histone modification 16307 7430 GO:00165…. query_1 TRUE 0.0000001 245 9028 180 0.0199380 0.7346939 GO:1904951 GO:BP positive regulation of establishment of protein localization 16307 25552 GO:00451…. query_1 TRUE 0.0000001 104 9028 86 0.0095259 0.8269231 GO:0006986 GO:BP response to unfolded protein 16307 2682 GO:0035966 query_1 TRUE 0.0000001 87 9028 74 0.0081967 0.8505747 GO:0007032 GO:BP endosome organization 16307 2712 GO:00102…. query_1 TRUE 0.0000001 429 9028 296 0.0327869 0.6899767 GO:0048285 GO:BP organelle fission 16307 13447 GO:0006996 query_1 TRUE 0.0000001 65 9028 58 0.0064245 0.8923077 GO:0090501 GO:BP RNA phosphodiester bond hydrolysis 16307 19482 GO:00160…. query_1 TRUE 0.0000001 61 9028 55 0.0060922 0.9016393 GO:2000144 GO:BP positive regulation of DNA-templated transcription initiation 16307 26902 GO:00063…. query_1 TRUE 0.0000001 97 9028 81 0.0089721 0.8350515 GO:0007006 GO:BP mitochondrial membrane organization 16307 2693 GO:00070…. query_1 TRUE 0.0000001 154 9028 120 0.0132920 0.7792208 GO:0015931 GO:BP nucleobase-containing compound transport 16307 5172 GO:00717…. query_1 TRUE 0.0000001 123 9028 99 0.0109659 0.8048780 GO:0032434 GO:BP regulation of proteasomal ubiquitin-dependent protein catabolic process 16307 8024 GO:00431…. query_1 TRUE 0.0000001 83 9028 71 0.0078644 0.8554217 GO:0010833 GO:BP telomere maintenance via telomere lengthening 16307 4577 GO:0000723 query_1 TRUE 0.0000001 126 9028 101 0.0111874 0.8015873 GO:0045727 GO:BP positive regulation of translation 16307 12343 GO:00064…. query_1 TRUE 0.0000001 761 9028 498 0.0551617 0.6544021 GO:0044092 GO:BP negative regulation of molecular function 16307 11612 GO:0065009 query_1 TRUE 0.0000002 162 9028 125 0.0138458 0.7716049 GO:0016482 GO:BP cytosolic transport 16307 5392 GO:0046907 query_1 TRUE 0.0000002 64 9028 57 0.0063137 0.8906250 GO:1905818 GO:BP regulation of chromosome separation 16307 26303 GO:00513…. query_1 TRUE 0.0000002 64 9028 57 0.0063137 0.8906250 GO:0043967 GO:BP histone H4 acetylation 16307 11551 GO:0016573 query_1 TRUE 0.0000002 96 9028 80 0.0088613 0.8333333 GO:0061014 GO:BP positive regulation of mRNA catabolic process 16307 16104 GO:00064…. query_1 TRUE 0.0000002 379 9028 264 0.0292424 0.6965699 GO:0051223 GO:BP regulation of protein transport 16307 14428 GO:00150…. query_1 TRUE 0.0000002 60 9028 54 0.0059814 0.9000000 GO:0051306 GO:BP mitotic sister chromatid separation 16307 14489 GO:00000…. query_1 TRUE 0.0000002 75 9028 65 0.0071998 0.8666667 GO:0046822 GO:BP regulation of nucleocytoplasmic transport 16307 13175 GO:00069…. query_1 TRUE 0.0000002 703 9028 462 0.0511741 0.6571835 GO:0060548 GO:BP negative regulation of cell death 16307 15674 GO:00082…. query_1 TRUE 0.0000002 47 9028 44 0.0048737 0.9361702 GO:0032508 GO:BP DNA duplex unwinding 16307 8078 GO:0032392 query_1 TRUE 0.0000002 47 9028 44 0.0048737 0.9361702 GO:0030490 GO:BP maturation of SSU-rRNA 16307 7216 GO:00063…. query_1 TRUE 0.0000002 152 9028 118 0.0130704 0.7763158 GO:0043488 GO:BP regulation of mRNA stability 16307 11384 GO:00434…. query_1 TRUE 0.0000002 118 9028 95 0.0105228 0.8050847 GO:0006997 GO:BP nucleus organization 16307 2687 GO:0006996 query_1 TRUE 0.0000002 78 9028 67 0.0074214 0.8589744 GO:0044774 GO:BP mitotic DNA integrity checkpoint signaling 16307 11909 GO:00070…. query_1 TRUE 0.0000002 78 9028 67 0.0074214 0.8589744 GO:0050000 GO:BP chromosome localization 16307 14006 GO:0051640 query_1 TRUE 0.0000002 230 9028 169 0.0187195 0.7347826 GO:0043122 GO:BP regulation of I-kappaB kinase/NF-kappaB signaling 16307 11182 GO:00072…. query_1 TRUE 0.0000002 51 9028 47 0.0052060 0.9215686 GO:0006383 GO:BP transcription by RNA polymerase III 16307 2211 GO:0006351 query_1 TRUE 0.0000003 42 9028 40 0.0044307 0.9523810 GO:0090148 GO:BP membrane fission 16307 19201 GO:0061024 query_1 TRUE 0.0000003 37 9028 36 0.0039876 0.9729730 GO:0030488 GO:BP tRNA methylation 16307 7215 GO:00015…. query_1 TRUE 0.0000003 59 9028 53 0.0058706 0.8983051 GO:0006903 GO:BP vesicle targeting 16307 2627 GO:00099…. query_1 TRUE 0.0000003 55 9028 50 0.0055383 0.9090909 GO:0060261 GO:BP positive regulation of transcription initiation by RNA polymerase II 16307 15405 GO:00063…. query_1 TRUE 0.0000003 136 9028 107 0.0118520 0.7867647 GO:0098876 GO:BP vesicle-mediated transport to the plasma membrane 16307 20121 GO:00161…. query_1 TRUE 0.0000003 101 9028 83 0.0091936 0.8217822 GO:0006476 GO:BP protein deacetylation 16307 2277 GO:0035601 query_1 TRUE 0.0000003 276 9028 198 0.0219318 0.7173913 GO:1990778 GO:BP protein localization to cell periphery 16307 26682 GO:0008104 query_1 TRUE 0.0000003 568 9028 379 0.0419805 0.6672535 GO:0055086 GO:BP nucleobase-containing small molecule metabolic process 16307 15162 GO:00061…. query_1 TRUE 0.0000004 94 9028 78 0.0086398 0.8297872 GO:0042158 GO:BP lipoprotein biosynthetic process 16307 10623 GO:00346…. query_1 TRUE 0.0000004 129 9028 102 0.0112982 0.7906977 GO:0009411 GO:BP response to UV 16307 3568 GO:0009416 query_1 TRUE 0.0000004 87 9028 73 0.0080860 0.8390805 GO:0090305 GO:BP nucleic acid phosphodiester bond hydrolysis 16307 19343 GO:0090304 query_1 TRUE 0.0000004 87 9028 73 0.0080860 0.8390805 GO:0006405 GO:BP RNA export from nucleus 16307 2229 GO:00506…. query_1 TRUE 0.0000004 135 9028 106 0.0117412 0.7851852 GO:0010821 GO:BP regulation of mitochondrion organization 16307 4565 GO:00070…. query_1 TRUE 0.0000004 50 9028 46 0.0050953 0.9200000 GO:0016574 GO:BP histone ubiquitination 16307 5418 GO:00165…. query_1 TRUE 0.0000004 58 9028 52 0.0057599 0.8965517 GO:0010965 GO:BP regulation of mitotic sister chromatid separation 16307 4683 GO:00513…. query_1 TRUE 0.0000004 54 9028 49 0.0054276 0.9074074 GO:0032206 GO:BP positive regulation of telomere maintenance 16307 7859 GO:00007…. query_1 TRUE 0.0000004 41 9028 39 0.0043199 0.9512195 GO:0006984 GO:BP ER-nucleus signaling pathway 16307 2681 GO:0007165 query_1 TRUE 0.0000004 36 9028 35 0.0038768 0.9722222 GO:0006623 GO:BP protein targeting to vacuole 16307 2404 GO:00066…. query_1 TRUE 0.0000005 83 9028 70 0.0077537 0.8433735 GO:0034620 GO:BP cellular response to unfolded protein 16307 9198 GO:00069…. query_1 TRUE 0.0000005 83 9028 70 0.0077537 0.8433735 GO:0016575 GO:BP histone deacetylation 16307 5419 GO:00064…. query_1 TRUE 0.0000005 566 9028 377 0.0417590 0.6660777 GO:0051129 GO:BP negative regulation of cellular component organization 16307 14358 GO:00160…. query_1 TRUE 0.0000005 93 9028 77 0.0085290 0.8279570 GO:1901989 GO:BP positive regulation of cell cycle phase transition 16307 23057 GO:00447…. query_1 TRUE 0.0000005 93 9028 77 0.0085290 0.8279570 GO:0006497 GO:BP protein lipidation 16307 2291 GO:00362…. query_1 TRUE 0.0000006 470 9028 318 0.0352237 0.6765957 GO:0043086 GO:BP negative regulation of catalytic activity 16307 11158 GO:00440…. query_1 TRUE 0.0000006 61 9028 54 0.0059814 0.8852459 GO:0070972 GO:BP protein localization to endoplasmic reticulum 16307 17473 GO:0033365 query_1 TRUE 0.0000006 79 9028 67 0.0074214 0.8481013 GO:0006513 GO:BP protein monoubiquitination 16307 2302 GO:0016567 query_1 TRUE 0.0000007 178 9028 134 0.0148427 0.7528090 GO:0045732 GO:BP positive regulation of protein catabolic process 16307 12347 GO:00098…. query_1 TRUE 0.0000007 57 9028 51 0.0056491 0.8947368 GO:0006998 GO:BP nuclear envelope organization 16307 2688 GO:00069…. query_1 TRUE 0.0000008 130 9028 102 0.0112982 0.7846154 GO:0006352 GO:BP DNA-templated transcription initiation 16307 2190 GO:00063…. query_1 TRUE 0.0000008 92 9028 76 0.0084183 0.8260870 GO:0061157 GO:BP mRNA destabilization 16307 16237 GO:00171…. query_1 TRUE 0.0000008 267 9028 191 0.0211564 0.7153558 GO:0051098 GO:BP regulation of binding 16307 14336 GO:0065009 query_1 TRUE 0.0000008 2309 9028 1398 0.1548516 0.6054569 GO:0006357 GO:BP regulation of transcription by RNA polymerase II 16307 2195 GO:00063…. query_1 TRUE 0.0000009 95 9028 78 0.0086398 0.8210526 GO:0050779 GO:BP RNA destabilization 16307 14082 GO:00064…. query_1 TRUE 0.0000009 71 9028 61 0.0067568 0.8591549 GO:0061912 GO:BP selective autophagy 16307 16752 GO:0016236 query_1 TRUE 0.0000011 52 9028 47 0.0052060 0.9038462 GO:0045839 GO:BP negative regulation of mitotic nuclear division 16307 12431 GO:00070…. query_1 TRUE 0.0000011 52 9028 47 0.0052060 0.9038462 GO:0090329 GO:BP regulation of DNA-templated DNA replication 16307 19367 GO:00062…. query_1 TRUE 0.0000011 81 9028 68 0.0075321 0.8395062 GO:0000079 GO:BP regulation of cyclin-dependent protein serine/threonine kinase activity 16307 30 GO:00719…. query_1 TRUE 0.0000012 74 9028 63 0.0069783 0.8513514 GO:0044773 GO:BP mitotic DNA damage checkpoint signaling 16307 11908 GO:00000…. query_1 TRUE 0.0000012 74 9028 63 0.0069783 0.8513514 GO:1905897 GO:BP regulation of response to endoplasmic reticulum stress 16307 26370 GO:00349…. query_1 TRUE 0.0000012 107 9028 86 0.0095259 0.8037383 GO:0022900 GO:BP electron transport chain 16307 7027 GO:0006091 query_1 TRUE 0.0000013 94 9028 77 0.0085290 0.8191489 GO:0033108 GO:BP mitochondrial respiratory chain complex assembly 16307 8512 GO:00070…. query_1 TRUE 0.0000013 314 9028 220 0.0243686 0.7006369 GO:0006338 GO:BP chromatin remodeling 16307 2186 GO:0006325 query_1 TRUE 0.0000013 84 9028 70 0.0077537 0.8333333 GO:1904029 GO:BP regulation of cyclin-dependent protein kinase activity 16307 24742 GO:00458…. query_1 TRUE 0.0000013 1339 9028 834 0.0923793 0.6228529 GO:0016192 GO:BP vesicle-mediated transport 16307 5325 GO:0006810 query_1 TRUE 0.0000015 59 9028 52 0.0057599 0.8813559 GO:0072332 GO:BP intrinsic apoptotic signaling pathway by p53 class mediator 16307 18457 GO:00723…. query_1 TRUE 0.0000017 1012 9028 641 0.0710013 0.6333992 GO:0009968 GO:BP negative regulation of signal transduction 16307 3900 GO:00071…. query_1 TRUE 0.0000017 267 9028 190 0.0210456 0.7116105 GO:0051301 GO:BP cell division 16307 14484 GO:0009987 query_1 TRUE 0.0000017 172 9028 129 0.0142889 0.7500000 GO:0007179 GO:BP transforming growth factor beta receptor signaling pathway 16307 2820 GO:00071…. query_1 TRUE 0.0000017 80 9028 67 0.0074214 0.8375000 GO:0008630 GO:BP intrinsic apoptotic signaling pathway in response to DNA damage 16307 3309 GO:00069…. query_1 TRUE 0.0000017 106 9028 85 0.0094152 0.8018868 GO:0007088 GO:BP regulation of mitotic nuclear division 16307 2752 GO:00073…. query_1 TRUE 0.0000017 47 9028 43 0.0047630 0.9148936 GO:0044380 GO:BP protein localization to cytoskeleton 16307 11707 GO:0033365 query_1 TRUE 0.0000017 206 9028 151 0.0167257 0.7330097 GO:0090068 GO:BP positive regulation of cell cycle process 16307 19133 GO:00105…. query_1 TRUE 0.0000021 438 9028 296 0.0327869 0.6757991 GO:0010942 GO:BP positive regulation of cell death 16307 4664 GO:00082…. query_1 TRUE 0.0000021 145 9028 111 0.0122951 0.7655172 GO:0046488 GO:BP phosphatidylinositol metabolic process 16307 12979 GO:0006650 query_1 TRUE 0.0000021 139 9028 107 0.0118520 0.7697842 GO:0032869 GO:BP cellular response to insulin stimulus 16307 8334 GO:00328…. query_1 TRUE 0.0000021 130 9028 101 0.0111874 0.7769231 GO:2000779 GO:BP regulation of double-strand break repair 16307 27478 GO:00062…. query_1 TRUE 0.0000030 129 9028 100 0.0110767 0.7751938 GO:0050684 GO:BP regulation of mRNA processing 16307 14042 GO:00063…. query_1 TRUE 0.0000031 229 9028 165 0.0182765 0.7205240 GO:0051222 GO:BP positive regulation of protein transport 16307 14427 GO:00150…. query_1 TRUE 0.0000031 1325 9028 823 0.0911608 0.6211321 GO:0007010 GO:BP cytoskeleton organization 16307 2697 GO:0006996 query_1 TRUE 0.0000032 75 9028 63 0.0069783 0.8400000 GO:0031058 GO:BP positive regulation of histone modification 16307 7432 GO:00165…. query_1 TRUE 0.0000035 37 9028 35 0.0038768 0.9459459 GO:0022616 GO:BP DNA strand elongation 16307 7020 GO:0006259 query_1 TRUE 0.0000035 264 9028 187 0.0207133 0.7083333 GO:2001233 GO:BP regulation of apoptotic signaling pathway 16307 27880 GO:00099…. query_1 TRUE 0.0000035 386 9028 263 0.0291316 0.6813472 GO:0000280 GO:BP nuclear division 16307 82 GO:0048285 query_1 TRUE 0.0000039 341 9028 235 0.0260301 0.6891496 GO:0006644 GO:BP phospholipid metabolic process 16307 2422 GO:00067…. query_1 TRUE 0.0000039 628 9028 410 0.0454143 0.6528662 GO:0043069 GO:BP negative regulation of programmed cell death 16307 11154 GO:00125…. query_1 TRUE 0.0000041 71 9028 60 0.0066460 0.8450704 GO:0031397 GO:BP negative regulation of protein ubiquitination 16307 7589 GO:00165…. query_1 TRUE 0.0000041 1127 9028 706 0.0782012 0.6264419 GO:0051174 GO:BP regulation of phosphorus metabolic process 16307 14402 GO:00067…. query_1 TRUE 0.0000042 53 9028 47 0.0052060 0.8867925 GO:0032210 GO:BP regulation of telomere maintenance via telomerase 16307 7863 GO:00070…. query_1 TRUE 0.0000042 53 9028 47 0.0052060 0.8867925 GO:0071479 GO:BP cellular response to ionizing radiation 16307 17788 GO:00102…. query_1 TRUE 0.0000042 53 9028 47 0.0052060 0.8867925 GO:0042255 GO:BP ribosome assembly 16307 10688 GO:00422…. query_1 TRUE 0.0000046 45 9028 41 0.0045414 0.9111111 GO:0072698 GO:BP protein localization to microtubule cytoskeleton 16307 18616 GO:0044380 query_1 TRUE 0.0000047 1126 9028 705 0.0780904 0.6261101 GO:0019220 GO:BP regulation of phosphate metabolic process 16307 5933 GO:00067…. query_1 TRUE 0.0000050 151 9028 114 0.0126274 0.7549669 GO:0032868 GO:BP response to insulin 16307 8333 GO:0043434 query_1 TRUE 0.0000059 56 9028 49 0.0054276 0.8750000 GO:0045005 GO:BP DNA-templated DNA replication maintenance of fidelity 16307 11986 GO:00062…. query_1 TRUE 0.0000059 56 9028 49 0.0054276 0.8750000 GO:2000756 GO:BP regulation of peptidyl-lysine acetylation 16307 27458 GO:00183…. query_1 TRUE 0.0000066 31 9028 30 0.0033230 0.9677419 GO:0099022 GO:BP vesicle tethering 16307 20209 GO:00069…. query_1 TRUE 0.0000067 52 9028 46 0.0050953 0.8846154 GO:0072666 GO:BP establishment of protein localization to vacuole 16307 18592 GO:00725…. query_1 TRUE 0.0000067 52 9028 46 0.0050953 0.8846154 GO:0033047 GO:BP regulation of mitotic sister chromatid segregation 16307 8472 GO:00000…. query_1 TRUE 0.0000069 99 9028 79 0.0087506 0.7979798 GO:0022904 GO:BP respiratory electron transport chain 16307 7028 GO:00229…. query_1 TRUE 0.0000069 506 9028 335 0.0371068 0.6620553 GO:0006753 GO:BP nucleoside phosphate metabolic process 16307 2518 GO:00067…. query_1 TRUE 0.0000070 83 9028 68 0.0075321 0.8192771 GO:0010389 GO:BP regulation of G2/M transition of mitotic cell cycle 16307 4202 GO:00000…. query_1 TRUE 0.0000072 144 9028 109 0.0120735 0.7569444 GO:0043393 GO:BP regulation of protein binding 16307 11313 GO:0051098 query_1 TRUE 0.0000072 48 9028 43 0.0047630 0.8958333 GO:0051972 GO:BP regulation of telomerase activity 16307 14915 GO:00513…. query_1 TRUE 0.0000072 73 9028 61 0.0067568 0.8356164 GO:0070828 GO:BP heterochromatin organization 16307 17383 GO:0006338 query_1 TRUE 0.0000074 751 9028 482 0.0533895 0.6418109 GO:0000122 GO:BP negative regulation of transcription by RNA polymerase II 16307 51 GO:00063…. query_1 TRUE 0.0000074 3797 9028 2236 0.2476739 0.5888860 GO:0051234 GO:BP establishment of localization 16307 14436 GO:0051179 query_1 TRUE 0.0000078 66 9028 56 0.0062029 0.8484848 GO:1900182 GO:BP positive regulation of protein localization to nucleus 16307 21490 GO:00345…. query_1 TRUE 0.0000079 117 9028 91 0.0100798 0.7777778 GO:1903052 GO:BP positive regulation of proteolysis involved in protein catabolic process 16307 23921 GO:00458…. query_1 TRUE 0.0000079 126 9028 97 0.0107444 0.7698413 GO:0016571 GO:BP histone methylation 16307 5416 GO:00064…. query_1 TRUE 0.0000080 282 9028 197 0.0218210 0.6985816 GO:0006650 GO:BP glycerophospholipid metabolic process 16307 2427 GO:00066…. query_1 TRUE 0.0000082 89 9028 72 0.0079752 0.8089888 GO:1901796 GO:BP regulation of signal transduction by p53 class mediator 16307 22870 GO:00723…. query_1 TRUE 0.0000086 2739 9028 1634 0.1809925 0.5965681 GO:0023051 GO:BP regulation of signaling 16307 7036 GO:00230…. query_1 TRUE 0.0000086 25 9028 25 0.0027692 1.0000000 GO:0006622 GO:BP protein targeting to lysosome 16307 2403 GO:00066…. query_1 TRUE 0.0000096 62 9028 53 0.0058706 0.8548387 GO:0048524 GO:BP positive regulation of viral process 16307 13628 GO:00160…. query_1 TRUE 0.0000096 62 9028 53 0.0058706 0.8548387 GO:1904356 GO:BP regulation of telomere maintenance via telomere lengthening 16307 25033 GO:00108…. query_1 TRUE 0.0000097 98 9028 78 0.0086398 0.7959184 GO:0034968 GO:BP histone lysine methylation 16307 9262 GO:00165…. query_1 TRUE 0.0000103 205 9028 148 0.0163934 0.7219512 GO:0070085 GO:BP glycosylation 16307 16944 GO:0008152 query_1 TRUE 0.0000103 246 9028 174 0.0192734 0.7073171 GO:0072659 GO:BP protein localization to plasma membrane 16307 18586 GO:00726…. query_1 TRUE 0.0000103 134 9028 102 0.0112982 0.7611940 GO:0048284 GO:BP organelle fusion 16307 13446 GO:0006996 query_1 TRUE 0.0000105 496 9028 328 0.0363314 0.6612903 GO:0009117 GO:BP nucleotide metabolic process 16307 3378 GO:0006753 query_1 TRUE 0.0000105 131 9028 100 0.0110767 0.7633588 GO:2001242 GO:BP regulation of intrinsic apoptotic signaling pathway 16307 27889 GO:00971…. query_1 TRUE 0.0000105 191 9028 139 0.0153965 0.7277487 GO:0045333 GO:BP cellular respiration 16307 12133 GO:0015980 query_1 TRUE 0.0000108 122 9028 94 0.0104121 0.7704918 GO:0000086 GO:BP G2/M transition of mitotic cell cycle 16307 36 GO:00447…. query_1 TRUE 0.0000109 119 9028 92 0.0101905 0.7731092 GO:0019079 GO:BP viral genome replication 16307 5898 GO:00160…. query_1 TRUE 0.0000112 39 9028 36 0.0039876 0.9230769 GO:0007020 GO:BP microtubule nucleation 16307 2703 GO:00002…. query_1 TRUE 0.0000113 47 9028 42 0.0046522 0.8936170 GO:0071806 GO:BP protein transmembrane transport 16307 18005 GO:00150…. query_1 TRUE 0.0000115 65 9028 55 0.0060922 0.8461538 GO:0031507 GO:BP heterochromatin formation 16307 7631 GO:00458…. query_1 TRUE 0.0000132 94 9028 75 0.0083075 0.7978723 GO:0071901 GO:BP negative regulation of protein serine/threonine kinase activity 16307 18063 GO:00064…. query_1 TRUE 0.0000134 162 9028 120 0.0132920 0.7407407 GO:0043281 GO:BP regulation of cysteine-type endopeptidase activity involved in apoptotic process 16307 11247 GO:2000116 query_1 TRUE 0.0000136 68 9028 57 0.0063137 0.8382353 GO:0030330 GO:BP DNA damage response, signal transduction by p53 class mediator 16307 7178 GO:00427…. query_1 TRUE 0.0000136 68 9028 57 0.0063137 0.8382353 GO:1902117 GO:BP positive regulation of organelle assembly 16307 23171 GO:00106…. query_1 TRUE 0.0000136 68 9028 57 0.0063137 0.8382353 GO:0090307 GO:BP mitotic spindle assembly 16307 19345 GO:00000…. query_1 TRUE 0.0000157 71 9028 59 0.0065352 0.8309859 GO:0051028 GO:BP mRNA transport 16307 14285 GO:0050658 query_1 TRUE 0.0000157 71 9028 59 0.0065352 0.8309859 GO:0010822 GO:BP positive regulation of mitochondrion organization 16307 4566 GO:00070…. query_1 TRUE 0.0000158 34 9028 32 0.0035445 0.9411765 GO:0000460 GO:BP maturation of 5.8S rRNA 16307 162 GO:0006364 query_1 TRUE 0.0000158 34 9028 32 0.0035445 0.9411765 GO:0035520 GO:BP monoubiquitinated protein deubiquitination 16307 9619 GO:0016579 query_1 TRUE 0.0000160 50 9028 44 0.0048737 0.8800000 GO:0035065 GO:BP regulation of histone acetylation 16307 9312 GO:00165…. query_1 TRUE 0.0000167 614 9028 398 0.0440851 0.6482085 GO:0043066 GO:BP negative regulation of apoptotic process 16307 11151 GO:00069…. query_1 TRUE 0.0000174 64 9028 54 0.0059814 0.8437500 GO:0043687 GO:BP post-translational protein modification 16307 11501 GO:0036211 query_1 TRUE 0.0000174 64 9028 54 0.0059814 0.8437500 GO:0006406 GO:BP mRNA export from nucleus 16307 2230 GO:00064…. query_1 TRUE 0.0000177 57 9028 49 0.0054276 0.8596491 GO:0034033 GO:BP purine nucleoside bisphosphate biosynthetic process 16307 8863 GO:00338…. query_1 TRUE 0.0000177 57 9028 49 0.0054276 0.8596491 GO:0033866 GO:BP nucleoside bisphosphate biosynthetic process 16307 8850 GO:00338…. query_1 TRUE 0.0000177 46 9028 41 0.0045414 0.8913043 GO:0071985 GO:BP multivesicular body sorting pathway 16307 18125 GO:0016192 query_1 TRUE 0.0000177 57 9028 49 0.0054276 0.8596491 GO:0034030 GO:BP ribonucleoside bisphosphate biosynthetic process 16307 8860 GO:00338…. query_1 TRUE 0.0000177 46 9028 41 0.0045414 0.8913043 GO:0065002 GO:BP intracellular protein transmembrane transport 16307 16923 GO:00068…. query_1 TRUE 0.0000177 90 9028 72 0.0079752 0.8000000 GO:0009062 GO:BP fatty acid catabolic process 16307 3330 GO:00066…. query_1 TRUE 0.0000185 29 9028 28 0.0031015 0.9655172 GO:1900101 GO:BP regulation of endoplasmic reticulum unfolded protein response 16307 21413 GO:00099…. query_1 TRUE 0.0000186 42 9028 38 0.0042091 0.9047619 GO:0071763 GO:BP nuclear membrane organization 16307 17979 GO:00069…. query_1 TRUE 0.0000186 42 9028 38 0.0042091 0.9047619 GO:0009299 GO:BP mRNA transcription 16307 3538 GO:00063…. query_1 TRUE 0.0000194 254 9028 178 0.0197164 0.7007874 GO:0015980 GO:BP energy derivation by oxidation of organic compounds 16307 5216 GO:0006091 query_1 TRUE 0.0000202 1066 9028 665 0.0736597 0.6238274 GO:0023057 GO:BP negative regulation of signaling 16307 7039 GO:00230…. query_1 TRUE 0.0000204 117 9028 90 0.0099690 0.7692308 GO:0045739 GO:BP positive regulation of DNA repair 16307 12353 GO:00062…. query_1 TRUE 0.0000214 325 9028 222 0.0245902 0.6830769 GO:0009100 GO:BP glycoprotein metabolic process 16307 3364 GO:00195…. query_1 TRUE 0.0000226 248 9028 174 0.0192734 0.7016129 GO:0071214 GO:BP cellular response to abiotic stimulus 16307 17545 GO:00096…. query_1 TRUE 0.0000226 248 9028 174 0.0192734 0.7016129 GO:0104004 GO:BP cellular response to environmental stimulus 16307 20403 GO:0051716 query_1 TRUE 0.0000229 70 9028 58 0.0064245 0.8285714 GO:0051298 GO:BP centrosome duplication 16307 14481 GO:00070…. query_1 TRUE 0.0000244 277 9028 192 0.0212672 0.6931408 GO:0006310 GO:BP DNA recombination 16307 2175 GO:0006259 query_1 TRUE 0.0000248 134 9028 101 0.0111874 0.7537313 GO:0044839 GO:BP cell cycle G2/M phase transition 16307 11950 GO:0044770 query_1 TRUE 0.0000255 154 9028 114 0.0126274 0.7402597 GO:0050792 GO:BP regulation of viral process 16307 14089 GO:00160…. query_1 TRUE 0.0000256 290 9028 200 0.0221533 0.6896552 GO:0071900 GO:BP regulation of protein serine/threonine kinase activity 16307 18062 GO:0045859 query_1 TRUE 0.0000256 73 9028 60 0.0066460 0.8219178 GO:0045814 GO:BP negative regulation of gene expression, epigenetic 16307 12410 GO:00106…. query_1 TRUE 0.0000257 33 9028 31 0.0034338 0.9393939 GO:0032212 GO:BP positive regulation of telomere maintenance via telomerase 16307 7865 GO:00070…. query_1 TRUE 0.0000258 23 9028 23 0.0025476 1.0000000 GO:0000469 GO:BP cleavage involved in rRNA processing 16307 171 GO:00063…. query_1 TRUE 0.0000260 128 9028 97 0.0107444 0.7578125 GO:0040029 GO:BP epigenetic regulation of gene expression 16307 10536 GO:00063…. query_1 TRUE 0.0000275 119 9028 91 0.0100798 0.7647059 GO:0031929 GO:BP TOR signaling 16307 7732 GO:0035556 query_1 TRUE 0.0000275 45 9028 40 0.0044307 0.8888889 GO:0045841 GO:BP negative regulation of mitotic metaphase/anaphase transition 16307 12433 GO:00070…. query_1 TRUE 0.0000275 45 9028 40 0.0044307 0.8888889 GO:0044088 GO:BP regulation of vacuole organization 16307 11608 GO:00070…. query_1 TRUE 0.0000275 45 9028 40 0.0044307 0.8888889 GO:0031577 GO:BP spindle checkpoint signaling 16307 7665 GO:0000075 query_1 TRUE 0.0000281 104 9028 81 0.0089721 0.7788462 GO:1901800 GO:BP positive regulation of proteasomal protein catabolic process 16307 22874 GO:00104…. query_1 TRUE 0.0000291 37 9028 34 0.0037661 0.9189189 GO:0044786 GO:BP cell cycle DNA replication 16307 11917 GO:00062…. query_1 TRUE 0.0000293 41 9028 37 0.0040984 0.9024390 GO:0043620 GO:BP regulation of DNA-templated transcription in response to stress 16307 11467 GO:00063…. query_1 TRUE 0.0000293 41 9028 37 0.0040984 0.9024390 GO:0098927 GO:BP vesicle-mediated transport between endosomal compartments 16307 20154 GO:0016192 query_1 TRUE 0.0000310 28 9028 27 0.0029907 0.9642857 GO:0000470 GO:BP maturation of LSU-rRNA 16307 172 GO:00063…. query_1 TRUE 0.0000317 195 9028 140 0.0155073 0.7179487 GO:2000116 GO:BP regulation of cysteine-type endopeptidase activity 16307 26875 GO:0052548 query_1 TRUE 0.0000323 59 9028 50 0.0055383 0.8474576 GO:0033059 GO:BP cellular pigmentation 16307 8483 GO:00099…. query_1 TRUE 0.0000334 69 9028 57 0.0063137 0.8260870 GO:1901983 GO:BP regulation of protein acetylation 16307 23051 GO:00064…. query_1 TRUE 0.0000354 88 9028 70 0.0077537 0.7954545 GO:0042773 GO:BP ATP synthesis coupled electron transport 16307 10990 GO:00061…. query_1 TRUE 0.0000354 88 9028 70 0.0077537 0.7954545 GO:0042775 GO:BP mitochondrial ATP synthesis coupled electron transport 16307 10992 GO:0042773 query_1 TRUE 0.0000369 730 9028 465 0.0515064 0.6369863 GO:0061024 GO:BP membrane organization 16307 16108 GO:0016043 query_1 TRUE 0.0000376 118 9028 90 0.0099690 0.7627119 GO:1903322 GO:BP positive regulation of protein modification by small protein conjugation or removal 16307 24125 GO:00314…. query_1 TRUE 0.0000382 115 9028 88 0.0097475 0.7652174 GO:0042157 GO:BP lipoprotein metabolic process 16307 10622 GO:0019538 query_1 TRUE 0.0000403 55 9028 47 0.0052060 0.8545455 GO:0031122 GO:BP cytoplasmic microtubule organization 16307 7468 GO:00002…. query_1 TRUE 0.0000409 183 9028 132 0.0146212 0.7213115 GO:0006457 GO:BP protein folding 16307 2267 GO:0009987 query_1 TRUE 0.0000413 293 9028 201 0.0222641 0.6860068 GO:0016311 GO:BP dephosphorylation 16307 5358 GO:0006796 query_1 TRUE 0.0000418 1060 9028 659 0.0729951 0.6216981 GO:0010648 GO:BP negative regulation of cell communication 16307 4412 GO:00071…. query_1 TRUE 0.0000419 32 9028 30 0.0033230 0.9375000 GO:0006270 GO:BP DNA replication initiation 16307 2143 GO:00062…. query_1 TRUE 0.0000419 32 9028 30 0.0033230 0.9375000 GO:1905898 GO:BP positive regulation of response to endoplasmic reticulum stress 16307 26371 GO:00349…. query_1 TRUE 0.0000419 32 9028 30 0.0033230 0.9375000 GO:0036257 GO:BP multivesicular body organization 16307 10094 GO:0007032 query_1 TRUE 0.0000419 32 9028 30 0.0033230 0.9375000 GO:0033522 GO:BP histone H2A ubiquitination 16307 8741 GO:0016574 query_1 TRUE 0.0000426 44 9028 39 0.0043199 0.8863636 GO:1901976 GO:BP regulation of cell cycle checkpoint 16307 23046 GO:00000…. query_1 TRUE 0.0000426 44 9028 39 0.0043199 0.8863636 GO:0071174 GO:BP mitotic spindle checkpoint signaling 16307 17539 GO:00070…. query_1 TRUE 0.0000426 44 9028 39 0.0043199 0.8863636 GO:0071173 GO:BP spindle assembly checkpoint signaling 16307 17538 GO:0031577 query_1 TRUE 0.0000426 44 9028 39 0.0043199 0.8863636 GO:0007094 GO:BP mitotic spindle assembly checkpoint signaling 16307 2756 GO:00458…. query_1 TRUE 0.0000426 221 9028 156 0.0172796 0.7058824 GO:0140546 GO:BP defense response to symbiont 16307 21051 GO:0098542 query_1 TRUE 0.0000426 221 9028 156 0.0172796 0.7058824 GO:0051607 GO:BP defense response to virus 16307 14694 GO:00096…. query_1 TRUE 0.0000435 152 9028 112 0.0124058 0.7368421 GO:0007030 GO:BP Golgi organization 16307 2710 GO:00069…. query_1 TRUE 0.0000438 132 9028 99 0.0109659 0.7500000 GO:1901136 GO:BP carbohydrate derivative catabolic process 16307 22308 GO:19011…. query_1 TRUE 0.0000440 22 9028 22 0.0024369 1.0000000 GO:0000466 GO:BP maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 16307 168 GO:0000460 query_1 TRUE 0.0000440 22 9028 22 0.0024369 1.0000000 GO:0043968 GO:BP histone H2A acetylation 16307 11552 GO:0016573 query_1 TRUE 0.0000452 81 9028 65 0.0071998 0.8024691 GO:1903321 GO:BP negative regulation of protein modification by small protein conjugation or removal 16307 24124 GO:00314…. query_1 TRUE 0.0000459 40 9028 36 0.0039876 0.9000000 GO:0032509 GO:BP endosome transport via multivesicular body sorting pathway 16307 8079 GO:00161…. query_1 TRUE 0.0000461 36 9028 33 0.0036553 0.9166667 GO:1904358 GO:BP positive regulation of telomere maintenance via telomere lengthening 16307 25035 GO:00108…. query_1 TRUE 0.0000474 84 9028 67 0.0074214 0.7976190 GO:0045185 GO:BP maintenance of protein location 16307 12078 GO:00081…. query_1 TRUE 0.0000482 51 9028 44 0.0048737 0.8627451 GO:0019083 GO:BP viral transcription 16307 5902 GO:00160…. query_1 TRUE 0.0000519 93 9028 73 0.0080860 0.7849462 GO:1902749 GO:BP regulation of cell cycle G2/M phase transition 16307 23647 GO:00448…. query_1 TRUE 0.0000520 111 9028 85 0.0094152 0.7657658 GO:0030010 GO:BP establishment of cell polarity 16307 7047 GO:0007163 query_1 TRUE 0.0000576 47 9028 41 0.0045414 0.8723404 GO:1902100 GO:BP negative regulation of metaphase/anaphase transition of cell cycle 16307 23154 GO:00447…. query_1 TRUE 0.0000576 47 9028 41 0.0045414 0.8723404 GO:0033046 GO:BP negative regulation of sister chromatid segregation 16307 8471 GO:00008…. query_1 TRUE 0.0000576 47 9028 41 0.0045414 0.8723404 GO:0033048 GO:BP negative regulation of mitotic sister chromatid segregation 16307 8473 GO:00000…. query_1 TRUE 0.0000576 47 9028 41 0.0045414 0.8723404 GO:2000816 GO:BP negative regulation of mitotic sister chromatid separation 16307 27515 GO:00109…. query_1 TRUE 0.0000636 2752 9028 1631 0.1806602 0.5926599 GO:0010646 GO:BP regulation of cell communication 16307 4410 GO:00071…. query_1 TRUE 0.0000665 1003 9028 624 0.0691183 0.6221336 GO:0042325 GO:BP regulation of phosphorylation 16307 10721 GO:00163…. query_1 TRUE 0.0000670 119 9028 90 0.0099690 0.7563025 GO:0051783 GO:BP regulation of nuclear division 16307 14807 GO:00002…. query_1 TRUE 0.0000686 31 9028 29 0.0032122 0.9354839 GO:0036258 GO:BP multivesicular body assembly 16307 10095 GO:00362…. query_1 TRUE 0.0000698 386 9028 257 0.0284670 0.6658031 GO:0019693 GO:BP ribose phosphate metabolic process 16307 6365 GO:00067…. query_1 TRUE 0.0000698 86 9028 68 0.0075321 0.7906977 GO:2000781 GO:BP positive regulation of double-strand break repair 16307 27480 GO:00063…. query_1 TRUE 0.0000709 713 9028 453 0.0501772 0.6353436 GO:0009628 GO:BP response to abiotic stimulus 16307 3642 GO:0050896 query_1 TRUE 0.0000714 57 9028 48 0.0053168 0.8421053 GO:0051784 GO:BP negative regulation of nuclear division 16307 14808 GO:00002…. query_1 TRUE 0.0000727 39 9028 35 0.0038768 0.8974359 GO:0045022 GO:BP early endosome to late endosome transport 16307 11997 GO:00164…. query_1 TRUE 0.0000727 39 9028 35 0.0038768 0.8974359 GO:0002183 GO:BP cytoplasmic translational initiation 16307 755 GO:00021…. query_1 TRUE 0.0000727 39 9028 35 0.0038768 0.8974359 GO:0090114 GO:BP COPII-coated vesicle budding 16307 19173 GO:00068…. query_1 TRUE 0.0000731 95 9028 74 0.0081967 0.7789474 GO:2000060 GO:BP positive regulation of ubiquitin-dependent protein catabolic process 16307 26820 GO:00065…. query_1 TRUE 0.0000736 35 9028 32 0.0035445 0.9142857 GO:0043162 GO:BP ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 16307 11207 GO:0006511 query_1 TRUE 0.0000736 35 9028 32 0.0035445 0.9142857 GO:0010390 GO:BP histone monoubiquitination 16307 4203 GO:00065…. query_1 TRUE 0.0000736 35 9028 32 0.0035445 0.9142857 GO:0032506 GO:BP cytokinetic process 16307 8076 GO:00009…. query_1 TRUE 0.0000736 35 9028 32 0.0035445 0.9142857 GO:0006301 GO:BP postreplication repair 16307 2166 GO:0006281 query_1 TRUE 0.0000736 35 9028 32 0.0035445 0.9142857 GO:0072595 GO:BP maintenance of protein localization in organelle 16307 18565 GO:00325…. query_1 TRUE 0.0000736 35 9028 32 0.0035445 0.9142857 GO:0043618 GO:BP regulation of transcription from RNA polymerase II promoter in response to stress 16307 11465 GO:00063…. query_1 TRUE 0.0000736 35 9028 32 0.0035445 0.9142857 GO:0019068 GO:BP virion assembly 16307 5889 GO:00160…. query_1 TRUE 0.0000751 175 9028 126 0.0139566 0.7200000 GO:0070646 GO:BP protein modification by small protein removal 16307 17285 GO:00065…. query_1 TRUE 0.0000755 21 9028 21 0.0023261 1.0000000 GO:0034508 GO:BP centromere complex assembly 16307 9177 GO:00512…. query_1 TRUE 0.0000755 21 9028 21 0.0023261 1.0000000 GO:0051315 GO:BP attachment of mitotic spindle microtubules to kinetochore 16307 14495 GO:00070…. query_1 TRUE 0.0000755 21 9028 21 0.0023261 1.0000000 GO:0036498 GO:BP IRE1-mediated unfolded protein response 16307 10223 GO:0030968 query_1 TRUE 0.0000755 70 9028 57 0.0063137 0.8142857 GO:0016441 GO:BP post-transcriptional gene silencing 16307 5381 GO:00106…. query_1 TRUE 0.0000795 183 9028 131 0.0145104 0.7158470 GO:0043413 GO:BP macromolecule glycosylation 16307 11327 GO:00434…. query_1 TRUE 0.0000795 183 9028 131 0.0145104 0.7158470 GO:0006486 GO:BP protein glycosylation 16307 2284 GO:00091…. query_1 TRUE 0.0000824 158 9028 115 0.0127381 0.7278481 GO:0008213 GO:BP protein alkylation 16307 3228 GO:0036211 query_1 TRUE 0.0000824 158 9028 115 0.0127381 0.7278481 GO:0006479 GO:BP protein methylation 16307 2280 GO:00082…. query_1 TRUE 0.0000840 1310 9028 802 0.0888347 0.6122137 GO:0044093 GO:BP positive regulation of molecular function 16307 11613 GO:0065009 query_1 TRUE 0.0000845 169 9028 122 0.0135135 0.7218935 GO:0032200 GO:BP telomere organization 16307 7853 GO:0051276 query_1 TRUE 0.0000849 26 9028 25 0.0027692 0.9615385 GO:0006515 GO:BP protein quality control for misfolded or incompletely synthesized proteins 16307 2303 GO:0051603 query_1 TRUE 0.0000883 53 9028 45 0.0049845 0.8490566 GO:0006360 GO:BP transcription by RNA polymerase I 16307 2197 GO:0006351 query_1 TRUE 0.0000883 118 9028 89 0.0098582 0.7542373 GO:0017015 GO:BP regulation of transforming growth factor beta receptor signaling pathway 16307 5443 GO:00071…. query_1 TRUE 0.0000883 53 9028 45 0.0049845 0.8490566 GO:0098781 GO:BP ncRNA transcription 16307 20080 GO:0006351 query_1 TRUE 0.0000899 79 9028 63 0.0069783 0.7974684 GO:0034644 GO:BP cellular response to UV 16307 9213 GO:00094…. query_1 TRUE 0.0000951 109 9028 83 0.0091936 0.7614679 GO:0071453 GO:BP cellular response to oxygen levels 16307 17763 GO:00704…. query_1 TRUE 0.0000976 244 9028 169 0.0187195 0.6926230 GO:0031667 GO:BP response to nutrient levels 16307 7714 GO:0009991 query_1 TRUE 0.0000992 100 9028 77 0.0085290 0.7700000 GO:0048024 GO:BP regulation of mRNA splicing, via spliceosome 16307 13291 GO:00003…. query_1 TRUE 0.0001014 42 9028 37 0.0040984 0.8809524 GO:0006284 GO:BP base-excision repair 16307 2156 GO:0006281 query_1 TRUE 0.0001099 49 9028 42 0.0046522 0.8571429 GO:0051985 GO:BP negative regulation of chromosome segregation 16307 14924 GO:00070…. query_1 TRUE 0.0001099 49 9028 42 0.0046522 0.8571429 GO:0051438 GO:BP regulation of ubiquitin-protein transferase activity 16307 14567 GO:0051338 query_1 TRUE 0.0001099 30 9028 28 0.0031015 0.9333333 GO:0070979 GO:BP protein K11-linked ubiquitination 16307 17477 GO:0000209 query_1 TRUE 0.0001099 49 9028 42 0.0046522 0.8571429 GO:1905819 GO:BP negative regulation of chromosome separation 16307 26304 GO:00513…. query_1 TRUE 0.0001119 396 9028 262 0.0290208 0.6616162 GO:0007264 GO:BP small GTPase mediated signal transduction 16307 2877 GO:0035556 query_1 TRUE 0.0001126 38 9028 34 0.0037661 0.8947368 GO:0000387 GO:BP spliceosomal snRNP assembly 16307 122 GO:00003…. query_1 TRUE 0.0001128 812 9028 510 0.0564909 0.6280788 GO:0007017 GO:BP microtubule-based process 16307 2700 GO:0009987 query_1 TRUE 0.0001168 259 9028 178 0.0197164 0.6872587 GO:0009991 GO:BP response to extracellular stimulus 16307 3909 GO:0009605 query_1 TRUE 0.0001168 34 9028 31 0.0034338 0.9117647 GO:0042771 GO:BP intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 16307 10988 GO:00086…. query_1 TRUE 0.0001168 34 9028 31 0.0034338 0.9117647 GO:0051973 GO:BP positive regulation of telomerase activity 16307 14916 GO:00513…. query_1 TRUE 0.0001188 59 9028 49 0.0054276 0.8305085 GO:2000134 GO:BP negative regulation of G1/S transition of mitotic cell cycle 16307 26893 GO:00000…. query_1 TRUE 0.0001213 184 9028 131 0.0145104 0.7119565 GO:0007163 GO:BP establishment or maintenance of cell polarity 16307 2806 GO:0009987 query_1 TRUE 0.0001220 75 9028 60 0.0066460 0.8000000 GO:0051865 GO:BP protein autoubiquitination 16307 14830 GO:0016567 query_1 TRUE 0.0001226 219 9028 153 0.0169473 0.6986301 GO:0006470 GO:BP protein dephosphorylation 16307 2273 GO:00163…. query_1 TRUE 0.0001227 162 9028 117 0.0129597 0.7222222 GO:0009060 GO:BP aerobic respiration 16307 3328 GO:0045333 query_1 TRUE 0.0001283 248 9028 171 0.0189411 0.6895161 GO:0009165 GO:BP nucleotide biosynthetic process 16307 3423 GO:00091…. query_1 TRUE 0.0001321 52 9028 44 0.0048737 0.8461538 GO:0006890 GO:BP retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 16307 2617 GO:0048193 query_1 TRUE 0.0001356 458 9028 299 0.0331192 0.6528384 GO:0044283 GO:BP small molecule biosynthetic process 16307 11664 GO:00090…. query_1 TRUE 0.0001444 392 9028 259 0.0286885 0.6607143 GO:0005975 GO:BP carbohydrate metabolic process 16307 1894 GO:00442…. query_1 TRUE 0.0001453 65 9028 53 0.0058706 0.8153846 GO:0006635 GO:BP fatty acid beta-oxidation 16307 2413 GO:00090…. query_1 TRUE 0.0001453 65 9028 53 0.0058706 0.8153846 GO:0035194 GO:BP RNA-mediated post-transcriptional gene silencing 16307 9412 GO:00164…. query_1 TRUE 0.0001563 255 9028 175 0.0193841 0.6862745 GO:1901293 GO:BP nucleoside phosphate biosynthetic process 16307 22439 GO:00067…. query_1 TRUE 0.0001567 68 9028 55 0.0060922 0.8088235 GO:0006487 GO:BP protein N-linked glycosylation 16307 2285 GO:0006486 query_1 TRUE 0.0001568 41 9028 36 0.0039876 0.8780488 GO:2000785 GO:BP regulation of autophagosome assembly 16307 27484 GO:00000…. query_1 TRUE 0.0001659 48 9028 41 0.0045414 0.8541667 GO:0042149 GO:BP cellular response to glucose starvation 16307 10619 GO:0009267 query_1 TRUE 0.0001659 48 9028 41 0.0045414 0.8541667 GO:0061462 GO:BP protein localization to lysosome 16307 16510 GO:0072665 query_1 TRUE 0.0001659 48 9028 41 0.0045414 0.8541667 GO:0006611 GO:BP protein export from nucleus 16307 2393 GO:00068…. query_1 TRUE 0.0001772 37 9028 33 0.0036553 0.8918919 GO:0000731 GO:BP DNA synthesis involved in DNA repair 16307 222 GO:00062…. query_1 TRUE 0.0001772 345 9028 230 0.0254763 0.6666667 GO:0046486 GO:BP glycerolipid metabolic process 16307 12977 GO:0044255 query_1 TRUE 0.0001782 29 9028 27 0.0029907 0.9310345 GO:0035521 GO:BP monoubiquitinated histone deubiquitination 16307 9620 GO:00165…. query_1 TRUE 0.0001782 29 9028 27 0.0029907 0.9310345 GO:0035522 GO:BP monoubiquitinated histone H2A deubiquitination 16307 9621 GO:0035521 query_1 TRUE 0.0001782 29 9028 27 0.0029907 0.9310345 GO:1905508 GO:BP protein localization to microtubule organizing center 16307 26044 GO:0072698 query_1 TRUE 0.0001782 29 9028 27 0.0029907 0.9310345 GO:0045047 GO:BP protein targeting to ER 16307 12009 GO:00066…. query_1 TRUE 0.0001808 378 9028 250 0.0276916 0.6613757 GO:0009259 GO:BP ribonucleotide metabolic process 16307 3516 GO:00091…. query_1 TRUE 0.0001818 101 9028 77 0.0085290 0.7623762 GO:0031398 GO:BP positive regulation of protein ubiquitination 16307 7590 GO:00165…. query_1 TRUE 0.0001861 33 9028 30 0.0033230 0.9090909 GO:0033260 GO:BP nuclear DNA replication 16307 8579 GO:0044786 query_1 TRUE 0.0001861 33 9028 30 0.0033230 0.9090909 GO:0072599 GO:BP establishment of protein localization to endoplasmic reticulum 16307 18569 GO:00709…. query_1 TRUE 0.0001882 86 9028 67 0.0074214 0.7790698 GO:0007040 GO:BP lysosome organization 16307 2719 GO:0080171 query_1 TRUE 0.0001882 86 9028 67 0.0074214 0.7790698 GO:0080171 GO:BP lytic vacuole organization 16307 18972 GO:0007033 query_1 TRUE 0.0001902 201 9028 141 0.0156181 0.7014925 GO:0046390 GO:BP ribose phosphate biosynthetic process 16307 12900 GO:00196…. query_1 TRUE 0.0001921 61 9028 50 0.0055383 0.8196721 GO:0035195 GO:BP miRNA-mediated gene silencing 16307 9413 GO:0035194 query_1 TRUE 0.0001958 182 9028 129 0.0142889 0.7087912 GO:0030705 GO:BP cytoskeleton-dependent intracellular transport 16307 7288 GO:0046907 query_1 TRUE 0.0002019 44 9028 38 0.0042091 0.8636364 GO:0000959 GO:BP mitochondrial RNA metabolic process 16307 284 GO:0016070 query_1 TRUE 0.0002022 453 9028 295 0.0326761 0.6512141 GO:0051493 GO:BP regulation of cytoskeleton organization 16307 14611 GO:00070…. query_1 TRUE 0.0002063 206 9028 144 0.0159504 0.6990291 GO:0071559 GO:BP response to transforming growth factor beta 16307 17838 GO:0070848 query_1 TRUE 0.0002100 264 9028 180 0.0199380 0.6818182 GO:0009101 GO:BP glycoprotein biosynthetic process 16307 3365 GO:00091…. query_1 TRUE 0.0002136 308 9028 207 0.0229287 0.6720779 GO:0009314 GO:BP response to radiation 16307 3552 GO:0009628 query_1 TRUE 0.0002192 112 9028 84 0.0093044 0.7500000 GO:0006612 GO:BP protein targeting to membrane 16307 2394 GO:00066…. query_1 TRUE 0.0002227 67 9028 54 0.0059814 0.8059701 GO:0008333 GO:BP endosome to lysosome transport 16307 3254 GO:00070…. query_1 TRUE 0.0002233 19 9028 19 0.0021046 1.0000000 GO:0090670 GO:BP RNA localization to Cajal body 16307 19566 GO:0090685 query_1 TRUE 0.0002233 19 9028 19 0.0021046 1.0000000 GO:0000291 GO:BP nuclear-transcribed mRNA catabolic process, exonucleolytic 16307 88 GO:0000956 query_1 TRUE 0.0002233 19 9028 19 0.0021046 1.0000000 GO:0090671 GO:BP telomerase RNA localization to Cajal body 16307 19567 GO:00906…. query_1 TRUE 0.0002233 19 9028 19 0.0021046 1.0000000 GO:0090672 GO:BP telomerase RNA localization 16307 19568 GO:0006403 query_1 TRUE 0.0002233 19 9028 19 0.0021046 1.0000000 GO:0090685 GO:BP RNA localization to nucleus 16307 19577 GO:0006403 query_1 TRUE 0.0002248 143 9028 104 0.0115197 0.7272727 GO:0019318 GO:BP hexose metabolic process 16307 6018 GO:0005996 query_1 TRUE 0.0002271 274 9028 186 0.0206026 0.6788321 GO:0009895 GO:BP negative regulation of catabolic process 16307 3849 GO:00090…. query_1 TRUE 0.0002344 24 9028 23 0.0025476 0.9583333 GO:1903241 GO:BP U2-type prespliceosome assembly 16307 24062 GO:0000245 query_1 TRUE 0.0002344 24 9028 23 0.0025476 0.9583333 GO:0031468 GO:BP nuclear membrane reassembly 16307 7623 GO:00717…. query_1 TRUE 0.0002373 200 9028 140 0.0155073 0.7000000 GO:0071560 GO:BP cellular response to transforming growth factor beta stimulus 16307 17839 GO:00713…. query_1 TRUE 0.0002379 208 9028 145 0.0160611 0.6971154 GO:0031330 GO:BP negative regulation of cellular catabolic process 16307 7556 GO:00098…. query_1 TRUE 0.0002460 47 9028 40 0.0044307 0.8510638 GO:0031297 GO:BP replication fork processing 16307 7544 GO:0045005 query_1 TRUE 0.0002512 137 9028 100 0.0110767 0.7299270 GO:0031503 GO:BP protein-containing complex localization 16307 7627 GO:0051179 query_1 TRUE 0.0002519 57 9028 47 0.0052060 0.8245614 GO:0006893 GO:BP Golgi to plasma membrane transport 16307 2620 GO:00068…. query_1 TRUE 0.0002565 120 9028 89 0.0098582 0.7416667 GO:1903844 GO:BP regulation of cellular response to transforming growth factor beta stimulus 16307 24583 GO:00715…. query_1 TRUE 0.0002565 82 9028 64 0.0070891 0.7804878 GO:0019646 GO:BP aerobic electron transport chain 16307 6321 GO:00061…. query_1 TRUE 0.0002565 82 9028 64 0.0070891 0.7804878 GO:0022406 GO:BP membrane docking 16307 6994 GO:0009987 query_1 TRUE 0.0002582 148 9028 107 0.0118520 0.7229730 GO:0071478 GO:BP cellular response to radiation 16307 17787 GO:00093…. query_1 TRUE 0.0002596 330 9028 220 0.0243686 0.6666667 GO:0043254 GO:BP regulation of protein-containing complex assembly 16307 11233 GO:00440…. query_1 TRUE 0.0002712 36 9028 32 0.0035445 0.8888889 GO:0045324 GO:BP late endosome to vacuole transport 16307 12126 GO:00070…. query_1 TRUE 0.0002712 36 9028 32 0.0035445 0.8888889 GO:0042789 GO:BP mRNA transcription by RNA polymerase II 16307 11002 GO:00063…. query_1 TRUE 0.0002712 36 9028 32 0.0035445 0.8888889 GO:0040001 GO:BP establishment of mitotic spindle localization 16307 10510 GO:00512…. query_1 TRUE 0.0002718 167 9028 119 0.0131812 0.7125749 GO:0097191 GO:BP extrinsic apoptotic signaling pathway 16307 19704 GO:00071…. query_1 TRUE 0.0002757 156 9028 112 0.0124058 0.7179487 GO:0005996 GO:BP monosaccharide metabolic process 16307 1915 GO:00059…. query_1 TRUE 0.0003043 43 9028 37 0.0040984 0.8604651 GO:0008608 GO:BP attachment of spindle microtubules to kinetochore 16307 3296 GO:00224…. query_1 TRUE 0.0003127 161 9028 115 0.0127381 0.7142857 GO:0010952 GO:BP positive regulation of peptidase activity 16307 4672 GO:00458…. query_1 TRUE 0.0003148 150 9028 108 0.0119628 0.7200000 GO:0044272 GO:BP sulfur compound biosynthetic process 16307 11657 GO:00067…. query_1 TRUE 0.0003150 66 9028 53 0.0058706 0.8030303 GO:0000288 GO:BP nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 16307 85 GO:00009…. query_1 TRUE 0.0003363 177 9028 125 0.0138458 0.7062147 GO:0000910 GO:BP cytokinesis 16307 260 GO:00224…. query_1 TRUE 0.0003521 452 9028 293 0.0324546 0.6482301 GO:0006163 GO:BP purine nucleotide metabolic process 16307 2050 GO:00091…. query_1 TRUE 0.0003579 1291 9028 785 0.0869517 0.6080558 GO:0048585 GO:BP negative regulation of response to stimulus 16307 13679 GO:00485…. query_1 TRUE 0.0003579 84 9028 65 0.0071998 0.7738095 GO:0032436 GO:BP positive regulation of proteasomal ubiquitin-dependent protein catabolic process 16307 8026 GO:00324…. query_1 TRUE 0.0003681 39 9028 34 0.0037661 0.8717949 GO:0016233 GO:BP telomere capping 16307 5335 GO:0000723 query_1 TRUE 0.0003701 46 9028 39 0.0043199 0.8478261 GO:0032527 GO:BP protein exit from endoplasmic reticulum 16307 8086 GO:0006886 query_1 TRUE 0.0003729 113 9028 84 0.0093044 0.7433628 GO:0038127 GO:BP ERBB signaling pathway 16307 10321 GO:0007169 query_1 TRUE 0.0003736 198 9028 138 0.0152858 0.6969697 GO:0046777 GO:BP protein autophosphorylation 16307 13154 GO:0006468 query_1 TRUE 0.0003864 18 9028 18 0.0019938 1.0000000 GO:1904872 GO:BP regulation of telomerase RNA localization to Cajal body 16307 25483 GO:00328…. query_1 TRUE 0.0003864 18 9028 18 0.0019938 1.0000000 GO:0032785 GO:BP negative regulation of DNA-templated transcription, elongation 16307 8288 GO:00063…. query_1 TRUE 0.0003913 23 9028 22 0.0024369 0.9565217 GO:0051788 GO:BP response to misfolded protein 16307 14810 GO:0035966 query_1 TRUE 0.0003997 59 9028 48 0.0053168 0.8135593 GO:0010257 GO:BP NADH dehydrogenase complex assembly 16307 4132 GO:0065003 query_1 TRUE 0.0003997 59 9028 48 0.0053168 0.8135593 GO:0032981 GO:BP mitochondrial respiratory chain complex I assembly 16307 8432 GO:00102…. query_1 TRUE 0.0004268 35 9028 31 0.0034338 0.8857143 GO:0009123 GO:BP nucleoside monophosphate metabolic process 16307 3382 GO:0006753 query_1 TRUE 0.0004272 135 9028 98 0.0108551 0.7259259 GO:1903900 GO:BP regulation of viral life cycle 16307 24630 GO:00190…. query_1 TRUE 0.0004301 49 9028 41 0.0045414 0.8367347 GO:0032608 GO:BP interferon-beta production 16307 8121 GO:0032606 query_1 TRUE 0.0004301 49 9028 41 0.0045414 0.8367347 GO:0032648 GO:BP regulation of interferon-beta production 16307 8160 GO:00324…. query_1 TRUE 0.0004469 98 9028 74 0.0081967 0.7551020 GO:0007173 GO:BP epidermal growth factor receptor signaling pathway 16307 2815 GO:0038127 query_1 TRUE 0.0004492 65 9028 52 0.0057599 0.8000000 GO:1902807 GO:BP negative regulation of cell cycle G1/S phase transition 16307 23701 GO:00448…. query_1 TRUE 0.0004492 65 9028 52 0.0057599 0.8000000 GO:0016239 GO:BP positive regulation of macroautophagy 16307 5338 GO:00105…. query_1 TRUE 0.0004628 31 9028 28 0.0031015 0.9032258 GO:0000462 GO:BP maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 16307 164 GO:0030490 query_1 TRUE 0.0004628 27 9028 25 0.0027692 0.9259259 GO:1903146 GO:BP regulation of autophagy of mitochondrion 16307 23992 GO:00004…. query_1 TRUE 0.0004628 31 9028 28 0.0031015 0.9032258 GO:0019082 GO:BP viral protein processing 16307 5901 GO:00160…. query_1 TRUE 0.0004628 27 9028 25 0.0027692 0.9259259 GO:0031571 GO:BP mitotic G1 DNA damage checkpoint signaling 16307 7663 GO:00447…. query_1 TRUE 0.0004628 27 9028 25 0.0027692 0.9259259 GO:0071539 GO:BP protein localization to centrosome 16307 17827 GO:1905508 query_1 TRUE 0.0004628 31 9028 28 0.0031015 0.9032258 GO:0070198 GO:BP protein localization to chromosome, telomeric region 16307 17022 GO:0034502 query_1 TRUE 0.0004628 31 9028 28 0.0031015 0.9032258 GO:0006298 GO:BP mismatch repair 16307 2165 GO:0006281 query_1 TRUE 0.0004663 92 9028 70 0.0077537 0.7608696 GO:0008637 GO:BP apoptotic mitochondrial changes 16307 3312 GO:00069…. query_1 TRUE 0.0004681 390 9028 255 0.0282455 0.6538462 GO:0051090 GO:BP regulation of DNA-binding transcription factor activity 16307 14328 GO:00063…. query_1 TRUE 0.0004896 77 9028 60 0.0066460 0.7792208 GO:0051851 GO:BP modulation by host of symbiont process 16307 14828 GO:0051702 query_1 TRUE 0.0005007 194 9028 135 0.0149535 0.6958763 GO:0009260 GO:BP ribonucleotide biosynthetic process 16307 3517 GO:00091…. query_1 TRUE 0.0005190 137 9028 99 0.0109659 0.7226277 GO:0070507 GO:BP regulation of microtubule cytoskeleton organization 16307 17211 GO:00002…. query_1 TRUE 0.0005326 55 9028 45 0.0049845 0.8181818 GO:0097352 GO:BP autophagosome maturation 16307 19798 GO:00162…. query_1 TRUE 0.0005359 106 9028 79 0.0087506 0.7452830 GO:0090174 GO:BP organelle membrane fusion 16307 19226 GO:00482…. query_1 TRUE 0.0005497 45 9028 38 0.0042091 0.8444444 GO:0046824 GO:BP positive regulation of nucleocytoplasmic transport 16307 13177 GO:00069…. query_1 TRUE 0.0005497 45 9028 38 0.0042091 0.8444444 GO:0016578 GO:BP histone deubiquitination 16307 5421 GO:00165…. query_1 TRUE 0.0005549 272 9028 183 0.0202703 0.6727941 GO:0018105 GO:BP peptidyl-serine phosphorylation 16307 5525 GO:00064…. query_1 TRUE 0.0005589 38 9028 33 0.0036553 0.8684211 GO:0140467 GO:BP integrated stress response signaling 16307 21017 GO:0033554 query_1 TRUE 0.0005589 38 9028 33 0.0036553 0.8684211 GO:0008631 GO:BP intrinsic apoptotic signaling pathway in response to oxidative stress 16307 3310 GO:00364…. query_1 TRUE 0.0005718 58 9028 47 0.0052060 0.8103448 GO:0051568 GO:BP histone H3-K4 methylation 16307 14661 GO:0034968 query_1 TRUE 0.0005718 58 9028 47 0.0052060 0.8103448 GO:0032507 GO:BP maintenance of protein location in cell 16307 8077 GO:00451…. query_1 TRUE 0.0005759 100 9028 75 0.0083075 0.7500000 GO:0006367 GO:BP transcription initiation at RNA polymerase II promoter 16307 2203 GO:00063…. query_1 TRUE 0.0005861 328 9028 217 0.0240363 0.6615854 GO:0009615 GO:BP response to virus 16307 3634 GO:0051707 query_1 TRUE 0.0005959 97 9028 73 0.0080860 0.7525773 GO:0018107 GO:BP peptidyl-threonine phosphorylation 16307 5527 GO:00064…. query_1 TRUE 0.0006249 177 9028 124 0.0137350 0.7005650 GO:0070482 GO:BP response to oxygen levels 16307 17191 GO:0009628 query_1 TRUE 0.0006269 185 9028 129 0.0142889 0.6972973 GO:0006643 GO:BP membrane lipid metabolic process 16307 2421 GO:0044255 query_1 TRUE 0.0006311 48 9028 40 0.0044307 0.8333333 GO:0046605 GO:BP regulation of centrosome cycle 16307 13042 GO:00070…. query_1 TRUE 0.0006349 235 9028 160 0.0177226 0.6808511 GO:0030522 GO:BP intracellular receptor signaling pathway 16307 7237 GO:0007165 query_1 TRUE 0.0006456 22 9028 21 0.0023261 0.9545455 GO:0006268 GO:BP DNA unwinding involved in DNA replication 16307 2141 GO:00062…. query_1 TRUE 0.0006456 22 9028 21 0.0023261 0.9545455 GO:0010971 GO:BP positive regulation of G2/M transition of mitotic cell cycle 16307 4689 GO:00000…. query_1 TRUE 0.0006552 34 9028 30 0.0033230 0.8823529 GO:0006220 GO:BP pyrimidine nucleotide metabolic process 16307 2101 GO:00091…. query_1 TRUE 0.0006552 34 9028 30 0.0033230 0.8823529 GO:1903749 GO:BP positive regulation of establishment of protein localization to mitochondrion 16307 24509 GO:00726…. query_1 TRUE 0.0006592 17 9028 17 0.0018830 1.0000000 GO:0071243 GO:BP cellular response to arsenic-containing substance 16307 17574 GO:00466…. query_1 TRUE 0.0006592 17 9028 17 0.0018830 1.0000000 GO:0035720 GO:BP intraciliary anterograde transport 16307 9747 GO:0042073 query_1 TRUE 0.0006592 17 9028 17 0.0018830 1.0000000 GO:0051383 GO:BP kinetochore organization 16307 14544 GO:0051276 query_1 TRUE 0.0006592 17 9028 17 0.0018830 1.0000000 GO:0007097 GO:BP nuclear migration 16307 2759 GO:00469…. query_1 TRUE 0.0006641 82 9028 63 0.0069783 0.7682927 GO:0045069 GO:BP regulation of viral genome replication 16307 12031 GO:00190…. query_1 TRUE 0.0006705 778 9028 484 0.0536110 0.6221080 GO:0019752 GO:BP carboxylic acid metabolic process 16307 6401 GO:0043436 query_1 TRUE 0.0007215 286 9028 191 0.0211564 0.6678322 GO:0007265 GO:BP Ras protein signal transduction 16307 2878 GO:0007264 query_1 TRUE 0.0007271 30 9028 27 0.0029907 0.9000000 GO:0043276 GO:BP anoikis 16307 11242 GO:0006915 query_1 TRUE 0.0007271 30 9028 27 0.0029907 0.9000000 GO:1903955 GO:BP positive regulation of protein targeting to mitochondrion 16307 24684 GO:00066…. query_1 TRUE 0.0007271 30 9028 27 0.0029907 0.9000000 GO:0048199 GO:BP vesicle targeting, to, from or within Golgi 16307 13393 GO:00069…. query_1 TRUE 0.0007408 26 9028 24 0.0026584 0.9230769 GO:0046755 GO:BP viral budding 16307 13143 GO:00160…. query_1 TRUE 0.0007408 26 9028 24 0.0026584 0.9230769 GO:0032511 GO:BP late endosome to vacuole transport via multivesicular body sorting pathway 16307 8081 GO:00325…. query_1 TRUE 0.0007609 417 9028 270 0.0299070 0.6474820 GO:0044089 GO:BP positive regulation of cellular component biogenesis 16307 11609 GO:00440…. query_1 TRUE 0.0007609 200 9028 138 0.0152858 0.6900000 GO:0031098 GO:BP stress-activated protein kinase signaling cascade 16307 7445 GO:00335…. query_1 TRUE 0.0007645 99 9028 74 0.0081967 0.7474747 GO:0032006 GO:BP regulation of TOR signaling 16307 7757 GO:00319…. query_1 TRUE 0.0008126 44 9028 37 0.0040984 0.8409091 GO:1990928 GO:BP response to amino acid starvation 16307 26739 GO:0042594 query_1 TRUE 0.0008162 57 9028 46 0.0050953 0.8070175 GO:0032481 GO:BP positive regulation of type I interferon production 16307 8053 GO:00018…. query_1 TRUE 0.0008684 285 9028 190 0.0210456 0.6666667 GO:0018209 GO:BP peptidyl-serine modification 16307 5605 GO:0018193 query_1 TRUE 0.0008749 87 9028 66 0.0073106 0.7586207 GO:1990542 GO:BP mitochondrial transmembrane transport 16307 26594 GO:0055085 query_1 TRUE 0.0008946 84 9028 64 0.0070891 0.7619048 GO:2001235 GO:BP positive regulation of apoptotic signaling pathway 16307 27882 GO:00099…. query_1 TRUE 0.0008946 84 9028 64 0.0070891 0.7619048 GO:0008286 GO:BP insulin receptor signaling pathway 16307 3242 GO:00071…. query_1 TRUE 0.0008946 107 9028 79 0.0087506 0.7383178 GO:0043467 GO:BP regulation of generation of precursor metabolites and energy 16307 11365 GO:00060…. query_1 TRUE 0.0009065 802 9028 497 0.0550510 0.6197007 GO:0043436 GO:BP oxoacid metabolic process 16307 11340 GO:0006082 query_1 TRUE 0.0009224 78 9028 60 0.0066460 0.7692308 GO:0032456 GO:BP endocytic recycling 16307 8032 GO:00161…. query_1 TRUE 0.0009224 78 9028 60 0.0066460 0.7692308 GO:0046785 GO:BP microtubule polymerization 16307 13160 GO:00311…. query_1 TRUE 0.0009366 104 9028 77 0.0085290 0.7403846 GO:0006906 GO:BP vesicle fusion 16307 2629 GO:00160…. query_1 TRUE 0.0010101 115 9028 84 0.0093044 0.7304348 GO:0031109 GO:BP microtubule polymerization or depolymerization 16307 7455 GO:0000226 query_1 TRUE 0.0010241 50 9028 41 0.0045414 0.8200000 GO:0051293 GO:BP establishment of spindle localization 16307 14477 GO:00002…. query_1 TRUE 0.0010241 50 9028 41 0.0045414 0.8200000 GO:0046854 GO:BP phosphatidylinositol phosphate biosynthetic process 16307 13202 GO:0006661 query_1 TRUE 0.0010386 40 9028 34 0.0037661 0.8500000 GO:1902459 GO:BP positive regulation of stem cell population maintenance 16307 23455 GO:00198…. query_1 TRUE 0.0010416 477 9028 305 0.0337838 0.6394130 GO:0072521 GO:BP purine-containing compound metabolic process 16307 18528 GO:00067…. query_1 TRUE 0.0010551 317 9028 209 0.0231502 0.6593060 GO:0006790 GO:BP sulfur compound metabolic process 16307 2545 GO:0044237 query_1 TRUE 0.0010695 21 9028 20 0.0022153 0.9523810 GO:1905820 GO:BP positive regulation of chromosome separation 16307 26305 GO:00513…. query_1 TRUE 0.0010695 21 9028 20 0.0022153 0.9523810 GO:0034453 GO:BP microtubule anchoring 16307 9145 GO:0000226 query_1 TRUE 0.0010938 810 9028 501 0.0554940 0.6185185 GO:0006082 GO:BP organic acid metabolic process 16307 1999 GO:00442…. query_1 TRUE 0.0011312 367 9028 239 0.0264732 0.6512262 GO:0009150 GO:BP purine ribonucleotide metabolic process 16307 3409 GO:00061…. query_1 TRUE 0.0011401 16 9028 16 0.0017723 1.0000000 GO:0043982 GO:BP histone H4-K8 acetylation 16307 11563 GO:0043967 query_1 TRUE 0.0011401 89 9028 67 0.0074214 0.7528090 GO:0042147 GO:BP retrograde transport, endosome to Golgi 16307 10617 GO:00161…. query_1 TRUE 0.0011401 16 9028 16 0.0017723 1.0000000 GO:0043981 GO:BP histone H4-K5 acetylation 16307 11562 GO:0043967 query_1 TRUE 0.0011401 16 9028 16 0.0017723 1.0000000 GO:0000028 GO:BP ribosomal small subunit assembly 16307 14 GO:00226…. query_1 TRUE 0.0011401 89 9028 67 0.0074214 0.7528090 GO:0032606 GO:BP type I interferon production 16307 8119 GO:0001816 query_1 TRUE 0.0011401 89 9028 67 0.0074214 0.7528090 GO:0032479 GO:BP regulation of type I interferon production 16307 8051 GO:00018…. query_1 TRUE 0.0011422 29 9028 26 0.0028799 0.8965517 GO:0000423 GO:BP mitophagy 16307 138 GO:00004…. query_1 TRUE 0.0011422 29 9028 26 0.0028799 0.8965517 GO:0009161 GO:BP ribonucleoside monophosphate metabolic process 16307 3419 GO:0009123 query_1 TRUE 0.0011736 106 9028 78 0.0086398 0.7358491 GO:0018210 GO:BP peptidyl-threonine modification 16307 5606 GO:0018193 query_1 TRUE 0.0011881 25 9028 23 0.0025476 0.9200000 GO:0000002 GO:BP mitochondrial genome maintenance 16307 2 GO:0007005 query_1 TRUE 0.0011881 25 9028 23 0.0025476 0.9200000 GO:0009081 GO:BP branched-chain amino acid metabolic process 16307 3346 GO:0006520 query_1 TRUE 0.0011881 25 9028 23 0.0025476 0.9200000 GO:0019985 GO:BP translesion synthesis 16307 6459 GO:00007…. query_1 TRUE 0.0011881 25 9028 23 0.0025476 0.9200000 GO:1902751 GO:BP positive regulation of cell cycle G2/M phase transition 16307 23649 GO:00448…. query_1 TRUE 0.0011958 43 9028 36 0.0039876 0.8372093 GO:0034198 GO:BP cellular response to amino acid starvation 16307 8985 GO:00092…. query_1 TRUE 0.0012074 59 9028 47 0.0052060 0.7966102 GO:2000036 GO:BP regulation of stem cell population maintenance 16307 26797 GO:00198…. query_1 TRUE 0.0012194 203 9028 139 0.0153965 0.6847291 GO:0022604 GO:BP regulation of cell morphogenesis 16307 7009 GO:00009…. query_1 TRUE 0.0012245 117 9028 85 0.0094152 0.7264957 GO:0033865 GO:BP nucleoside bisphosphate metabolic process 16307 8849 GO:0006753 query_1 TRUE 0.0012245 117 9028 85 0.0094152 0.7264957 GO:0033875 GO:BP ribonucleoside bisphosphate metabolic process 16307 8852 GO:0033865 query_1 TRUE 0.0012245 80 9028 61 0.0067568 0.7625000 GO:0007029 GO:BP endoplasmic reticulum organization 16307 2709 GO:00069…. query_1 TRUE 0.0012245 117 9028 85 0.0094152 0.7264957 GO:0034032 GO:BP purine nucleoside bisphosphate metabolic process 16307 8862 GO:00338…. query_1 TRUE 0.0012615 65 9028 51 0.0056491 0.7846154 GO:0051205 GO:BP protein insertion into membrane 16307 14414 GO:00081…. query_1 TRUE 0.0012723 71 9028 55 0.0060922 0.7746479 GO:0000245 GO:BP spliceosomal complex assembly 16307 73 GO:00003…. query_1 TRUE 0.0012754 36 9028 31 0.0034338 0.8611111 GO:0006901 GO:BP vesicle coating 16307 2626 GO:00069…. query_1 TRUE 0.0012964 114 9028 83 0.0091936 0.7280702 GO:0018022 GO:BP peptidyl-lysine methylation 16307 5494 GO:00064…. query_1 TRUE 0.0013122 610 9028 383 0.0424236 0.6278689 GO:0010243 GO:BP response to organonitrogen compound 16307 4119 GO:00100…. query_1 TRUE 0.0013436 1258 9028 760 0.0841825 0.6041335 GO:0009967 GO:BP positive regulation of signal transduction 16307 3899 GO:00071…. query_1 TRUE 0.0013852 231 9028 156 0.0172796 0.6753247 GO:0072522 GO:BP purine-containing compound biosynthetic process 16307 18529 GO:00181…. query_1 TRUE 0.0014083 882 9028 542 0.0600354 0.6145125 GO:0001932 GO:BP regulation of protein phosphorylation 16307 568 GO:00064…. query_1 TRUE 0.0014579 1127 9028 684 0.0757643 0.6069210 GO:0006629 GO:BP lipid metabolic process 16307 2409 GO:00442…. query_1 TRUE 0.0014665 49 9028 40 0.0044307 0.8163265 GO:0043112 GO:BP receptor metabolic process 16307 11177 GO:0044260 query_1 TRUE 0.0014977 130 9028 93 0.0103013 0.7153846 GO:0051099 GO:BP positive regulation of binding 16307 14337 GO:00440…. query_1 TRUE 0.0015368 39 9028 33 0.0036553 0.8461538 GO:0036297 GO:BP interstrand cross-link repair 16307 10126 GO:0006281 query_1 TRUE 0.0015368 39 9028 33 0.0036553 0.8461538 GO:1905168 GO:BP positive regulation of double-strand break repair via homologous recombination 16307 25742 GO:00007…. query_1 TRUE 0.0015476 32 9028 28 0.0031015 0.8750000 GO:0009262 GO:BP deoxyribonucleotide metabolic process 16307 3519 GO:00091…. query_1 TRUE 0.0015677 52 9028 42 0.0046522 0.8076923 GO:0051653 GO:BP spindle localization 16307 14737 GO:00224…. query_1 TRUE 0.0016171 3640 9028 2113 0.2340496 0.5804945 GO:0006810 GO:BP transport 16307 2560 GO:0051234 query_1 TRUE 0.0016988 113 9028 82 0.0090829 0.7256637 GO:0006006 GO:BP glucose metabolic process 16307 1925 GO:0019318 query_1 TRUE 0.0017094 58 9028 46 0.0050953 0.7931034 GO:0072527 GO:BP pyrimidine-containing compound metabolic process 16307 18534 GO:00346…. query_1 TRUE 0.0017423 73 9028 56 0.0062029 0.7671233 GO:0140056 GO:BP organelle localization by membrane tethering 16307 20878 GO:00224…. query_1 TRUE 0.0017454 319 9028 209 0.0231502 0.6551724 GO:0006631 GO:BP fatty acid metabolic process 16307 2410 GO:00327…. query_1 TRUE 0.0017454 20 9028 19 0.0021046 0.9500000 GO:0051220 GO:BP cytoplasmic sequestering of protein 16307 14425 GO:0045185 query_1 TRUE 0.0017454 20 9028 19 0.0021046 0.9500000 GO:1904292 GO:BP regulation of ERAD pathway 16307 24970 GO:00365…. query_1 TRUE 0.0017454 20 9028 19 0.0021046 0.9500000 GO:0051984 GO:BP positive regulation of chromosome segregation 16307 14923 GO:00070…. query_1 TRUE 0.0017454 151 9028 106 0.0117412 0.7019868 GO:0010950 GO:BP positive regulation of endopeptidase activity 16307 4670 GO:00109…. query_1 TRUE 0.0017454 20 9028 19 0.0021046 0.9500000 GO:0071218 GO:BP cellular response to misfolded protein 16307 17549 GO:00359…. query_1 TRUE 0.0017454 20 9028 19 0.0021046 0.9500000 GO:1903232 GO:BP melanosome assembly 16307 24055 GO:00324…. query_1 TRUE 0.0017454 20 9028 19 0.0021046 0.9500000 GO:0046685 GO:BP response to arsenic-containing substance 16307 13103 GO:0042221 query_1 TRUE 0.0017458 196 9028 134 0.0148427 0.6836735 GO:0051403 GO:BP stress-activated MAPK cascade 16307 14555 GO:00001…. query_1 TRUE 0.0017501 64 9028 50 0.0055383 0.7812500 GO:0008625 GO:BP extrinsic apoptotic signaling pathway via death domain receptors 16307 3305 GO:0097191 query_1 TRUE 0.0017513 42 9028 35 0.0038768 0.8333333 GO:0072583 GO:BP clathrin-dependent endocytosis 16307 18560 GO:0006898 query_1 TRUE 0.0017648 28 9028 25 0.0027692 0.8928571 GO:0044819 GO:BP mitotic G1/S transition checkpoint signaling 16307 11935 GO:00070…. query_1 TRUE 0.0017648 28 9028 25 0.0027692 0.8928571 GO:0019076 GO:BP viral release from host cell 16307 5897 GO:00160…. query_1 TRUE 0.0017648 28 9028 25 0.0027692 0.8928571 GO:0016556 GO:BP mRNA modification 16307 5407 GO:00094…. query_1 TRUE 0.0017648 28 9028 25 0.0027692 0.8928571 GO:0090502 GO:BP RNA phosphodiester bond hydrolysis, endonucleolytic 16307 19483 GO:0090501 query_1 TRUE 0.0017648 28 9028 25 0.0027692 0.8928571 GO:0035891 GO:BP exit from host cell 16307 9874 GO:0044000 query_1 TRUE 0.0017719 110 9028 80 0.0088613 0.7272727 GO:0043280 GO:BP positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 16307 11246 GO:00432…. query_1 TRUE 0.0018479 93 9028 69 0.0076429 0.7419355 GO:0019395 GO:BP fatty acid oxidation 16307 6092 GO:00066…. query_1 TRUE 0.0018781 156 9028 109 0.0120735 0.6987179 GO:0016579 GO:BP protein deubiquitination 16307 5422 GO:0070646 query_1 TRUE 0.0018781 24 9028 22 0.0024369 0.9166667 GO:0018279 GO:BP protein N-linked glycosylation via asparagine 16307 5661 GO:0006487 query_1 TRUE 0.0018781 24 9028 22 0.0024369 0.9166667 GO:0009124 GO:BP nucleoside monophosphate biosynthetic process 16307 3383 GO:00091…. query_1 TRUE 0.0018781 24 9028 22 0.0024369 0.9166667 GO:0031145 GO:BP anaphase-promoting complex-dependent catabolic process 16307 7486 GO:0043161 query_1 TRUE 0.0018781 24 9028 22 0.0024369 0.9166667 GO:0070129 GO:BP regulation of mitochondrial translation 16307 16969 GO:00064…. query_1 TRUE 0.0019103 35 9028 30 0.0033230 0.8571429 GO:0007031 GO:BP peroxisome organization 16307 2711 GO:0006996 query_1 TRUE 0.0019103 118 9028 85 0.0094152 0.7203390 GO:0008360 GO:BP regulation of cell shape 16307 3269 GO:0022604 query_1 TRUE 0.0019148 15 9028 15 0.0016615 1.0000000 GO:1903894 GO:BP regulation of IRE1-mediated unfolded protein response 16307 24624 GO:00364…. query_1 TRUE 0.0019148 15 9028 15 0.0016615 1.0000000 GO:1904874 GO:BP positive regulation of telomerase RNA localization to Cajal body 16307 25485 GO:00485…. query_1 TRUE 0.0019148 15 9028 15 0.0016615 1.0000000 GO:0006271 GO:BP DNA strand elongation involved in DNA replication 16307 2144 GO:00062…. query_1 TRUE 0.0019148 15 9028 15 0.0016615 1.0000000 GO:0071025 GO:BP RNA surveillance 16307 17492 GO:0006401 query_1 TRUE 0.0019148 15 9028 15 0.0016615 1.0000000 GO:0006266 GO:BP DNA ligation 16307 2139 GO:0006259 query_1 TRUE 0.0019148 15 9028 15 0.0016615 1.0000000 GO:0006488 GO:BP dolichol-linked oligosaccharide biosynthetic process 16307 2286 GO:00064…. query_1 TRUE 0.0019705 104 9028 76 0.0084183 0.7307692 GO:0034614 GO:BP cellular response to reactive oxygen species 16307 9196 GO:00003…. query_1 TRUE 0.0019731 643 9028 401 0.0444174 0.6236392 GO:0030036 GO:BP actin cytoskeleton organization 16307 7057 GO:00070…. query_1 TRUE 0.0020062 161 9028 112 0.0124058 0.6956522 GO:0036293 GO:BP response to decreased oxygen levels 16307 10122 GO:0070482 query_1 TRUE 0.0020205 821 9028 505 0.0559371 0.6151035 GO:1902533 GO:BP positive regulation of intracellular signal transduction 16307 23504 GO:00099…. query_1 TRUE 0.0020847 285 9028 188 0.0208241 0.6596491 GO:0051604 GO:BP protein maturation 16307 14692 GO:00104…. query_1 TRUE 0.0021414 142 9028 100 0.0110767 0.7042254 GO:0010970 GO:BP transport along microtubule 16307 4688 GO:00070…. query_1 TRUE 0.0021989 98 9028 72 0.0079752 0.7346939 GO:0019827 GO:BP stem cell population maintenance 16307 6416 GO:00325…. query_1 TRUE 0.0023106 139 9028 98 0.0108551 0.7050360 GO:0046467 GO:BP membrane lipid biosynthetic process 16307 12961 GO:00066…. query_1 TRUE 0.0023274 31 9028 27 0.0029907 0.8709677 GO:0006506 GO:BP GPI anchor biosynthetic process 16307 2297 GO:00064…. query_1 TRUE 0.0023274 31 9028 27 0.0029907 0.8709677 GO:0000184 GO:BP nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 16307 61 GO:0000956 query_1 TRUE 0.0023274 31 9028 27 0.0029907 0.8709677 GO:2000758 GO:BP positive regulation of peptidyl-lysine acetylation 16307 27460 GO:00183…. query_1 TRUE 0.0023274 31 9028 27 0.0029907 0.8709677 GO:0070849 GO:BP response to epidermal growth factor 16307 17398 GO:0070848 query_1 TRUE 0.0023274 31 9028 27 0.0029907 0.8709677 GO:0000132 GO:BP establishment of mitotic spindle orientation 16307 53 GO:00400…. query_1 TRUE 0.0023274 31 9028 27 0.0029907 0.8709677 GO:0019692 GO:BP deoxyribose phosphate metabolic process 16307 6364 GO:00067…. query_1 TRUE 0.0023274 72 9028 55 0.0060922 0.7638889 GO:1901184 GO:BP regulation of ERBB signaling pathway 16307 22351 GO:00099…. query_1 TRUE 0.0023274 31 9028 27 0.0029907 0.8709677 GO:0009394 GO:BP 2’-deoxyribonucleotide metabolic process 16307 3555 GO:00092…. query_1 TRUE 0.0023422 57 9028 45 0.0049845 0.7894737 GO:0070534 GO:BP protein K63-linked ubiquitination 16307 17218 GO:0000209 query_1 TRUE 0.0023422 57 9028 45 0.0049845 0.7894737 GO:0010972 GO:BP negative regulation of G2/M transition of mitotic cell cycle 16307 4690 GO:00000…. query_1 TRUE 0.0023747 60 9028 47 0.0052060 0.7833333 GO:0006303 GO:BP double-strand break repair via nonhomologous end joining 16307 2168 GO:0006302 query_1 TRUE 0.0023747 60 9028 47 0.0052060 0.7833333 GO:0031124 GO:BP mRNA 3’-end processing 16307 7470 GO:00063…. query_1 TRUE 0.0023846 63 9028 49 0.0054276 0.7777778 GO:0032092 GO:BP positive regulation of protein binding 16307 7808 GO:00433…. query_1 TRUE 0.0024115 3358 9028 1951 0.2161054 0.5810006 GO:0048583 GO:BP regulation of response to stimulus 16307 13677 GO:00507…. query_1 TRUE 0.0024115 92 9028 68 0.0075321 0.7391304 GO:0042177 GO:BP negative regulation of protein catabolic process 16307 10632 GO:00098…. query_1 TRUE 0.0025310 41 9028 34 0.0037661 0.8292683 GO:0007099 GO:BP centriole replication 16307 2761 GO:00224…. query_1 TRUE 0.0025310 41 9028 34 0.0037661 0.8292683 GO:1901985 GO:BP positive regulation of protein acetylation 16307 23053 GO:00064…. query_1 TRUE 0.0025310 41 9028 34 0.0037661 0.8292683 GO:0006356 GO:BP regulation of transcription by RNA polymerase I 16307 2194 GO:00063…. query_1 TRUE 0.0026022 114 9028 82 0.0090829 0.7192982 GO:0031047 GO:BP RNA-mediated gene silencing 16307 7423 GO:0010629 query_1 TRUE 0.0026109 225 9028 151 0.0167257 0.6711111 GO:0006164 GO:BP purine nucleotide biosynthetic process 16307 2051 GO:00061…. query_1 TRUE 0.0027270 27 9028 24 0.0026584 0.8888889 GO:0062125 GO:BP regulation of mitochondrial gene expression 16307 16869 GO:00104…. query_1 TRUE 0.0027270 27 9028 24 0.0026584 0.8888889 GO:1901798 GO:BP positive regulation of signal transduction by p53 class mediator 16307 22872 GO:00723…. query_1 TRUE 0.0027270 27 9028 24 0.0026584 0.8888889 GO:2000819 GO:BP regulation of nucleotide-excision repair 16307 27517 GO:00062…. query_1 TRUE 0.0027624 301 9028 197 0.0218210 0.6544850 GO:0052547 GO:BP regulation of peptidase activity 16307 15045 GO:00301…. query_1 TRUE 0.0027715 44 9028 36 0.0039876 0.8181818 GO:0090224 GO:BP regulation of spindle organization 16307 19270 GO:00070…. query_1 TRUE 0.0027715 44 9028 36 0.0039876 0.8181818 GO:0032365 GO:BP intracellular lipid transport 16307 7980 GO:00068…. query_1 TRUE 0.0027715 44 9028 36 0.0039876 0.8181818 GO:0032008 GO:BP positive regulation of TOR signaling 16307 7759 GO:00319…. query_1 TRUE 0.0028090 19 9028 18 0.0019938 0.9473684 GO:0006743 GO:BP ubiquinone metabolic process 16307 2510 GO:1901661 query_1 TRUE 0.0028090 19 9028 18 0.0019938 0.9473684 GO:1901970 GO:BP positive regulation of mitotic sister chromatid separation 16307 23042 GO:00109…. query_1 TRUE 0.0028090 19 9028 18 0.0019938 0.9473684 GO:0009301 GO:BP snRNA transcription 16307 3540 GO:00160…. query_1 TRUE 0.0028090 19 9028 18 0.0019938 0.9473684 GO:0044090 GO:BP positive regulation of vacuole organization 16307 11610 GO:00070…. query_1 TRUE 0.0028090 19 9028 18 0.0019938 0.9473684 GO:0051647 GO:BP nucleus localization 16307 14731 GO:0051640 query_1 TRUE 0.0028331 34 9028 29 0.0032122 0.8529412 GO:0090151 GO:BP establishment of protein localization to mitochondrial membrane 16307 19204 GO:00070…. query_1 TRUE 0.0028331 34 9028 29 0.0032122 0.8529412 GO:0044743 GO:BP protein transmembrane import into intracellular organelle 16307 11896 GO:00718…. query_1 TRUE 0.0028416 97 9028 71 0.0078644 0.7319588 GO:0036294 GO:BP cellular response to decreased oxygen levels 16307 10123 GO:00362…. query_1 TRUE 0.0029542 47 9028 38 0.0042091 0.8085106 GO:0044818 GO:BP mitotic G2/M transition checkpoint 16307 11934 GO:00070…. query_1 TRUE 0.0029556 23 9028 21 0.0023261 0.9130435 GO:0035518 GO:BP histone H2A monoubiquitination 16307 9617 GO:00103…. query_1 TRUE 0.0030525 219 9028 147 0.0162827 0.6712329 GO:0009141 GO:BP nucleoside triphosphate metabolic process 16307 3400 GO:0006753 query_1 TRUE 0.0031308 71 9028 54 0.0059814 0.7605634 GO:0010569 GO:BP regulation of double-strand break repair via homologous recombination 16307 4339 GO:00000…. query_1 TRUE 0.0032587 14 9028 14 0.0015507 1.0000000 GO:0046112 GO:BP nucleobase biosynthetic process 16307 12665 GO:00091…. query_1 TRUE 0.0032587 14 9028 14 0.0015507 1.0000000 GO:0000463 GO:BP maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 16307 165 GO:0000470 query_1 TRUE 0.0032587 14 9028 14 0.0015507 1.0000000 GO:0030033 GO:BP microvillus assembly 16307 7054 GO:00325…. query_1 TRUE 0.0032587 14 9028 14 0.0015507 1.0000000 GO:0006999 GO:BP nuclear pore organization 16307 2689 GO:00069…. query_1 TRUE 0.0032587 65 9028 50 0.0055383 0.7692308 GO:0016073 GO:BP snRNA metabolic process 16307 5257 GO:0034660 query_1 TRUE 0.0032587 14 9028 14 0.0015507 1.0000000 GO:0034244 GO:BP negative regulation of transcription elongation by RNA polymerase II 16307 9014 GO:00063…. query_1 TRUE 0.0032587 14 9028 14 0.0015507 1.0000000 GO:1904294 GO:BP positive regulation of ERAD pathway 16307 24972 GO:00365…. query_1 TRUE 0.0032587 14 9028 14 0.0015507 1.0000000 GO:0070816 GO:BP phosphorylation of RNA polymerase II C-terminal domain 16307 17381 GO:00063…. query_1 TRUE 0.0032587 14 9028 14 0.0015507 1.0000000 GO:0071027 GO:BP nuclear RNA surveillance 16307 17494 GO:0071025 query_1 TRUE 0.0032587 185 9028 126 0.0139566 0.6810811 GO:0009152 GO:BP purine ribonucleotide biosynthetic process 16307 3411 GO:00061…. query_1 TRUE 0.0032647 59 9028 46 0.0050953 0.7796610 GO:1902750 GO:BP negative regulation of cell cycle G2/M phase transition 16307 23648 GO:00448…. query_1 TRUE 0.0032698 37 9028 31 0.0034338 0.8378378 GO:0051294 GO:BP establishment of spindle orientation 16307 14478 GO:00300…. query_1 TRUE 0.0032698 37 9028 31 0.0034338 0.8378378 GO:0042306 GO:BP regulation of protein import into nucleus 16307 10707 GO:00066…. query_1 TRUE 0.0032698 37 9028 31 0.0034338 0.8378378 GO:0017004 GO:BP cytochrome complex assembly 16307 5433 GO:0065003 query_1 TRUE 0.0032698 37 9028 31 0.0034338 0.8378378 GO:0032728 GO:BP positive regulation of interferon-beta production 16307 8238 GO:00324…. query_1 TRUE 0.0032892 88 9028 65 0.0071998 0.7386364 GO:0006637 GO:BP acyl-CoA metabolic process 16307 2415 GO:00091…. query_1 TRUE 0.0032892 88 9028 65 0.0071998 0.7386364 GO:0035383 GO:BP thioester metabolic process 16307 9545 GO:00067…. query_1 TRUE 0.0032892 113 9028 81 0.0089721 0.7168142 GO:0031123 GO:BP RNA 3’-end processing 16307 7469 GO:0006396 query_1 TRUE 0.0034588 85 9028 63 0.0069783 0.7411765 GO:0090263 GO:BP positive regulation of canonical Wnt signaling pathway 16307 19306 GO:00301…. query_1 TRUE 0.0034838 99 9028 72 0.0079752 0.7272727 GO:0098727 GO:BP maintenance of cell number 16307 20042 GO:0032502 query_1 TRUE 0.0034929 30 9028 26 0.0028799 0.8666667 GO:0045070 GO:BP positive regulation of viral genome replication 16307 12032 GO:00190…. query_1 TRUE 0.0034929 30 9028 26 0.0028799 0.8666667 GO:0045740 GO:BP positive regulation of DNA replication 16307 12354 GO:00062…. query_1 TRUE 0.0035344 129 9028 91 0.0100798 0.7054264 GO:2001056 GO:BP positive regulation of cysteine-type endopeptidase activity 16307 27746 GO:00109…. query_1 TRUE 0.0036504 40 9028 33 0.0036553 0.8250000 GO:0048753 GO:BP pigment granule organization 16307 13827 GO:00160…. query_1 TRUE 0.0036504 40 9028 33 0.0036553 0.8250000 GO:0032438 GO:BP melanosome organization 16307 8027 GO:0048753 query_1 TRUE 0.0037405 205 9028 138 0.0152858 0.6731707 GO:0044262 GO:BP cellular carbohydrate metabolic process 16307 11651 GO:00059…. query_1 TRUE 0.0037525 107 9028 77 0.0085290 0.7196262 GO:0061640 GO:BP cytoskeleton-dependent cytokinesis 16307 16622 GO:0000910 query_1 TRUE 0.0037685 79 9028 59 0.0065352 0.7468354 GO:2001243 GO:BP negative regulation of intrinsic apoptotic signaling pathway 16307 27890 GO:00971…. query_1 TRUE 0.0037901 158 9028 109 0.0120735 0.6898734 GO:0001666 GO:BP response to hypoxia 16307 398 GO:00069…. query_1 TRUE 0.0038585 134 9028 94 0.0104121 0.7014925 GO:0010634 GO:BP positive regulation of epithelial cell migration 16307 4398 GO:00106…. query_1 TRUE 0.0039552 43 9028 35 0.0038768 0.8139535 GO:0070265 GO:BP necrotic cell death 16307 17070 GO:0008219 query_1 TRUE 0.0039552 43 9028 35 0.0038768 0.8139535 GO:0010824 GO:BP regulation of centrosome duplication 16307 4568 GO:00466…. query_1 TRUE 0.0039701 962 9028 584 0.0646876 0.6070686 GO:0043085 GO:BP positive regulation of catalytic activity 16307 11157 GO:00440…. query_1 TRUE 0.0039924 104 9028 75 0.0083075 0.7211538 GO:1904375 GO:BP regulation of protein localization to cell periphery 16307 25052 GO:00328…. query_1 TRUE 0.0041816 26 9028 23 0.0025476 0.8846154 GO:0010458 GO:BP exit from mitosis 16307 4263 GO:00447…. query_1 TRUE 0.0041816 26 9028 23 0.0025476 0.8846154 GO:0090200 GO:BP positive regulation of release of cytochrome c from mitochondria 16307 19248 GO:00018…. query_1 TRUE 0.0041859 46 9028 37 0.0040984 0.8043478 GO:0006120 GO:BP mitochondrial electron transport, NADH to ubiquinone 16307 2030 GO:00196…. query_1 TRUE 0.0042069 33 9028 28 0.0031015 0.8484848 GO:0060606 GO:BP tube closure 16307 15724 GO:0035148 query_1 TRUE 0.0042069 33 9028 28 0.0031015 0.8484848 GO:0045943 GO:BP positive regulation of transcription by RNA polymerase I 16307 12512 GO:00063…. query_1 TRUE 0.0042069 33 9028 28 0.0031015 0.8484848 GO:0001843 GO:BP neural tube closure 16307 521 GO:00140…. query_1 TRUE 0.0043341 87 9028 64 0.0070891 0.7356322 GO:0030038 GO:BP contractile actin filament bundle assembly 16307 7059 GO:0051017 query_1 TRUE 0.0043341 87 9028 64 0.0070891 0.7356322 GO:0043149 GO:BP stress fiber assembly 16307 11197 GO:00300…. query_1 TRUE 0.0043500 278 9028 182 0.0201595 0.6546763 GO:0052548 GO:BP regulation of endopeptidase activity 16307 15046 GO:0052547 query_1 TRUE 0.0044429 52 9028 41 0.0045414 0.7884615 GO:0043154 GO:BP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 16307 11202 GO:00430…. query_1 TRUE 0.0044871 444 9028 281 0.0311254 0.6328829 GO:0051347 GO:BP positive regulation of transferase activity 16307 14526 GO:00430…. query_1 TRUE 0.0045380 18 9028 17 0.0018830 0.9444444 GO:0001522 GO:BP pseudouridine synthesis 16307 349 GO:0009451 query_1 TRUE 0.0045380 18 9028 17 0.0018830 0.9444444 GO:1903083 GO:BP protein localization to condensed chromosome 16307 23950 GO:0034502 query_1 TRUE 0.0045380 18 9028 17 0.0018830 0.9444444 GO:1901978 GO:BP positive regulation of cell cycle checkpoint 16307 23048 GO:00000…. query_1 TRUE 0.0045380 18 9028 17 0.0018830 0.9444444 GO:0006896 GO:BP Golgi to vacuole transport 16307 2622 GO:00068…. query_1 TRUE 0.0045380 18 9028 17 0.0018830 0.9444444 GO:0034501 GO:BP protein localization to kinetochore 16307 9172 GO:00714…. query_1 TRUE 0.0045380 84 9028 62 0.0068675 0.7380952 GO:0150115 GO:BP cell-substrate junction organization 16307 21244 GO:0034330 query_1 TRUE 0.0045380 18 9028 17 0.0018830 0.9444444 GO:0009083 GO:BP branched-chain amino acid catabolic process 16307 3348 GO:00090…. query_1 TRUE 0.0045380 18 9028 17 0.0018830 0.9444444 GO:0051988 GO:BP regulation of attachment of spindle microtubules to kinetochore 16307 14927 GO:00086…. query_1 TRUE 0.0045380 18 9028 17 0.0018830 0.9444444 GO:0032042 GO:BP mitochondrial DNA metabolic process 16307 7772 GO:00000…. query_1 TRUE 0.0046259 22 9028 20 0.0022153 0.9090909 GO:0039702 GO:BP viral budding via host ESCRT complex 16307 10498 GO:0046755 query_1 TRUE 0.0046259 22 9028 20 0.0022153 0.9090909 GO:2000209 GO:BP regulation of anoikis 16307 26962 GO:00429…. query_1 TRUE 0.0047714 125 9028 88 0.0097475 0.7040000 GO:0000302 GO:BP response to reactive oxygen species 16307 93 GO:00069…. query_1 TRUE 0.0047752 305 9028 198 0.0219318 0.6491803 GO:0044282 GO:BP small molecule catabolic process 16307 11663 GO:00090…. query_1 TRUE 0.0047819 36 9028 30 0.0033230 0.8333333 GO:0014020 GO:BP primary neural tube formation 16307 4737 GO:00018…. query_1 TRUE 0.0052070 807 9028 493 0.0546079 0.6109046 GO:0031401 GO:BP positive regulation of protein modification process 16307 7593 GO:00313…. query_1 TRUE 0.0052848 29 9028 25 0.0027692 0.8620690 GO:0051443 GO:BP positive regulation of ubiquitin-protein transferase activity 16307 14568 GO:00313…. query_1 TRUE 0.0052848 39 9028 32 0.0035445 0.8205128 GO:1902116 GO:BP negative regulation of organelle assembly 16307 23170 GO:00106…. query_1 TRUE 0.0052848 29 9028 25 0.0027692 0.8620690 GO:0033014 GO:BP tetrapyrrole biosynthetic process 16307 8449 GO:00181…. query_1 TRUE 0.0052848 29 9028 25 0.0027692 0.8620690 GO:0006779 GO:BP porphyrin-containing compound biosynthetic process 16307 2534 GO:00067…. query_1 TRUE 0.0052848 39 9028 32 0.0035445 0.8205128 GO:0007007 GO:BP inner mitochondrial membrane organization 16307 2694 GO:0007006 query_1 TRUE 0.0054661 151 9028 104 0.0115197 0.6887417 GO:0043433 GO:BP negative regulation of DNA-binding transcription factor activity 16307 11337 GO:00440…. query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:0000478 GO:BP endonucleolytic cleavage involved in rRNA processing 16307 180 GO:00004…. query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:0000479 GO:BP endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 16307 181 GO:0000478 query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:0043928 GO:BP exonucleolytic catabolism of deadenylated mRNA 16307 11523 GO:00002…. query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:0090235 GO:BP regulation of metaphase plate congression 16307 19280 GO:00328…. query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:1904816 GO:BP positive regulation of protein localization to chromosome, telomeric region 16307 25434 GO:00701…. query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:0051382 GO:BP kinetochore assembly 16307 14543 GO:00345…. query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:0032933 GO:BP SREBP signaling pathway 16307 8392 GO:00069…. query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:0000394 GO:BP RNA splicing, via endonucleolytic cleavage and ligation 16307 127 GO:0008380 query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:1900103 GO:BP positive regulation of endoplasmic reticulum unfolded protein response 16307 21415 GO:00099…. query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:0035331 GO:BP negative regulation of hippo signaling 16307 9508 GO:00353…. query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:1900025 GO:BP negative regulation of substrate adhesion-dependent cell spreading 16307 21349 GO:00108…. query_1 TRUE 0.0055058 13 9028 13 0.0014400 1.0000000 GO:0070262 GO:BP peptidyl-serine dephosphorylation 16307 17069 GO:0006470 query_1 TRUE 0.0055427 164 9028 112 0.0124058 0.6829268 GO:0070302 GO:BP regulation of stress-activated protein kinase signaling cascade 16307 17091 GO:00310…. query_1 TRUE 0.0055969 42 9028 34 0.0037661 0.8095238 GO:0044788 GO:BP modulation by host of viral process 16307 11919 GO:0051851 query_1 TRUE 0.0055969 42 9028 34 0.0037661 0.8095238 GO:0035384 GO:BP thioester biosynthetic process 16307 9546 GO:00353…. query_1 TRUE 0.0055969 42 9028 34 0.0037661 0.8095238 GO:0071616 GO:BP acyl-CoA biosynthetic process 16307 17879 GO:00066…. query_1 TRUE 0.0057410 66 9028 50 0.0055383 0.7575758 GO:0042058 GO:BP regulation of epidermal growth factor receptor signaling pathway 16307 10567 GO:00071…. query_1 TRUE 0.0057640 97 9028 70 0.0077537 0.7216495 GO:1903509 GO:BP liposaccharide metabolic process 16307 24289 GO:00066…. query_1 TRUE 0.0058624 45 9028 36 0.0039876 0.8000000 GO:0098534 GO:BP centriole assembly 16307 19977 GO:00310…. query_1 TRUE 0.0058624 45 9028 36 0.0039876 0.8000000 GO:0046902 GO:BP regulation of mitochondrial membrane permeability 16307 13234 GO:00068…. query_1 TRUE 0.0058879 63 9028 48 0.0053168 0.7619048 GO:0061077 GO:BP chaperone-mediated protein folding 16307 16160 GO:0006457 query_1 TRUE 0.0059634 124 9028 87 0.0096367 0.7016129 GO:0051100 GO:BP negative regulation of binding 16307 14338 GO:00440…. query_1 TRUE 0.0059764 132 9028 92 0.0101905 0.6969697 GO:0051017 GO:BP actin filament bundle assembly 16307 14282 GO:00226…. query_1 TRUE 0.0060195 48 9028 38 0.0042091 0.7916667 GO:0030865 GO:BP cortical cytoskeleton organization 16307 7348 GO:0007010 query_1 TRUE 0.0060195 48 9028 38 0.0042091 0.7916667 GO:0050435 GO:BP amyloid-beta metabolic process 16307 14012 GO:0006518 query_1 TRUE 0.0060835 57 9028 44 0.0048737 0.7719298 GO:0044091 GO:BP membrane biogenesis 16307 11611 GO:0044085 query_1 TRUE 0.0060835 57 9028 44 0.0048737 0.7719298 GO:0090559 GO:BP regulation of membrane permeability 16307 19518 GO:0065008 query_1 TRUE 0.0060987 51 9028 40 0.0044307 0.7843137 GO:0001836 GO:BP release of cytochrome c from mitochondria 16307 514 GO:00086…. query_1 TRUE 0.0061054 94 9028 68 0.0075321 0.7234043 GO:0071456 GO:BP cellular response to hypoxia 16307 17766 GO:00016…. query_1 TRUE 0.0061082 54 9028 42 0.0046522 0.7777778 GO:0071709 GO:BP membrane assembly 16307 17958 GO:00226…. query_1 TRUE 0.0061481 32 9028 27 0.0029907 0.8437500 GO:0051204 GO:BP protein insertion into mitochondrial membrane 16307 14413 GO:00068…. query_1 TRUE 0.0061481 32 9028 27 0.0029907 0.8437500 GO:0006505 GO:BP GPI anchor metabolic process 16307 2296 GO:00066…. query_1 TRUE 0.0061481 32 9028 27 0.0029907 0.8437500 GO:0000154 GO:BP rRNA modification 16307 55 GO:00063…. query_1 TRUE 0.0062590 113 9028 80 0.0088613 0.7079646 GO:0046165 GO:BP alcohol biosynthetic process 16307 12712 GO:00060…. query_1 TRUE 0.0062590 113 9028 80 0.0088613 0.7079646 GO:0044000 GO:BP movement in host 16307 11567 GO:0051701 query_1 TRUE 0.0062942 25 9028 22 0.0024369 0.8800000 GO:1903846 GO:BP positive regulation of cellular response to transforming growth factor beta stimulus 16307 24585 GO:00485…. query_1 TRUE 0.0062942 25 9028 22 0.0024369 0.8800000 GO:1904353 GO:BP regulation of telomere capping 16307 25030 GO:00162…. query_1 TRUE 0.0062942 25 9028 22 0.0024369 0.8800000 GO:0006099 GO:BP tricarboxylic acid cycle 16307 2011 GO:00090…. query_1 TRUE 0.0062942 25 9028 22 0.0024369 0.8800000 GO:0030511 GO:BP positive regulation of transforming growth factor beta receptor signaling pathway 16307 7228 GO:00071…. query_1 TRUE 0.0062942 25 9028 22 0.0024369 0.8800000 GO:0034063 GO:BP stress granule assembly 16307 8876 GO:0140694 query_1 TRUE 0.0063809 129 9028 90 0.0099690 0.6976744 GO:0006119 GO:BP oxidative phosphorylation 16307 2029 GO:0009060 query_1 TRUE 0.0067172 110 9028 78 0.0086398 0.7090909 GO:0034502 GO:BP protein localization to chromosome 16307 9173 GO:0033365 query_1 TRUE 0.0069573 394 9028 250 0.0276916 0.6345178 GO:0007015 GO:BP actin filament organization 16307 2699 GO:00300…. query_1 TRUE 0.0071331 71 9028 53 0.0058706 0.7464789 GO:0009408 GO:BP response to heat 16307 3565 GO:00069…. query_1 TRUE 0.0071406 204 9028 136 0.0150642 0.6666667 GO:0009199 GO:BP ribonucleoside triphosphate metabolic process 16307 3457 GO:0009141 query_1 TRUE 0.0071418 232 9028 153 0.0169473 0.6594828 GO:0044403 GO:BP biological process involved in symbiotic interaction 16307 11717 GO:0044419 query_1 TRUE 0.0072023 21 9028 19 0.0021046 0.9047619 GO:1903504 GO:BP regulation of mitotic spindle checkpoint 16307 24284 GO:00073…. query_1 TRUE 0.0072023 21 9028 19 0.0021046 0.9047619 GO:0090231 GO:BP regulation of spindle checkpoint 16307 19276 GO:00315…. query_1 TRUE 0.0072023 107 9028 76 0.0084183 0.7102804 GO:0072329 GO:BP monocarboxylic acid catabolic process 16307 18454 GO:00327…. query_1 TRUE 0.0072023 21 9028 19 0.0021046 0.9047619 GO:0033119 GO:BP negative regulation of RNA splicing 16307 8513 GO:00083…. query_1 TRUE 0.0072023 21 9028 19 0.0021046 0.9047619 GO:0032400 GO:BP melanosome localization 16307 8005 GO:0051875 query_1 TRUE 0.0072023 21 9028 19 0.0021046 0.9047619 GO:0051875 GO:BP pigment granule localization 16307 14836 GO:00330…. query_1 TRUE 0.0072023 21 9028 19 0.0021046 0.9047619 GO:0090266 GO:BP regulation of mitotic cell cycle spindle assembly checkpoint 16307 19309 GO:00070…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:2000811 GO:BP negative regulation of anoikis 16307 27510 GO:00430…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0006085 GO:BP acetyl-CoA biosynthetic process 16307 2002 GO:00060…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0044804 GO:BP autophagy of nucleus 16307 11924 GO:0006914 query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0044794 GO:BP positive regulation by host of viral process 16307 11922 GO:00160…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0043984 GO:BP histone H4-K16 acetylation 16307 11565 GO:0043967 query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0000076 GO:BP DNA replication checkpoint signaling 16307 28 GO:0031570 query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:2000786 GO:BP positive regulation of autophagosome assembly 16307 27485 GO:00000…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0043923 GO:BP positive regulation by host of viral transcription 16307 11521 GO:00190…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0061952 GO:BP midbody abscission 16307 16778 GO:00610…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0032510 GO:BP endosome to lysosome transport via multivesicular body sorting pathway 16307 8080 GO:00083…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0010755 GO:BP regulation of plasminogen activation 16307 4502 GO:00316…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:1901663 GO:BP quinone biosynthetic process 16307 22753 GO:00421…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0060382 GO:BP regulation of DNA strand elongation 16307 15519 GO:00226…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0006744 GO:BP ubiquinone biosynthetic process 16307 2511 GO:00067…. query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0055070 GO:BP copper ion homeostasis 16307 15149 GO:0055076 query_1 TRUE 0.0072039 17 9028 16 0.0017723 0.9411765 GO:0070200 GO:BP establishment of protein localization to telomere 16307 17024 GO:00701…. query_1 TRUE 0.0072510 96 9028 69 0.0076429 0.7187500 GO:0006664 GO:BP glycolipid metabolic process 16307 2440 GO:00066…. query_1 TRUE 0.0072708 68 9028 51 0.0056491 0.7500000 GO:0032922 GO:BP circadian regulation of gene expression 16307 8382 GO:00076…. query_1 TRUE 0.0073900 38 9028 31 0.0034338 0.8157895 GO:0001841 GO:BP neural tube formation 16307 519 GO:00018…. query_1 TRUE 0.0075512 65 9028 49 0.0054276 0.7538462 GO:2000117 GO:BP negative regulation of cysteine-type endopeptidase activity 16307 26876 GO:00109…. query_1 TRUE 0.0076991 28 9028 24 0.0026584 0.8571429 GO:0006084 GO:BP acetyl-CoA metabolic process 16307 2001 GO:0006637 query_1 TRUE 0.0076991 28 9028 24 0.0026584 0.8571429 GO:1901185 GO:BP negative regulation of ERBB signaling pathway 16307 22352 GO:00099…. query_1 TRUE 0.0076991 28 9028 24 0.0026584 0.8571429 GO:0001778 GO:BP plasma membrane repair 16307 464 GO:00070…. query_1 TRUE 0.0076991 28 9028 24 0.0026584 0.8571429 GO:1903513 GO:BP endoplasmic reticulum to cytosol transport 16307 24293 GO:0046907 query_1 TRUE 0.0076991 28 9028 24 0.0026584 0.8571429 GO:0071364 GO:BP cellular response to epidermal growth factor stimulus 16307 17688 GO:00708…. query_1 TRUE 0.0076991 28 9028 24 0.0026584 0.8571429 GO:0030970 GO:BP retrograde protein transport, ER to cytosol 16307 7388 GO:00325…. query_1 TRUE 0.0076991 28 9028 24 0.0026584 0.8571429 GO:0006359 GO:BP regulation of transcription by RNA polymerase III 16307 2196 GO:00063…. query_1 TRUE 0.0077309 170 9028 115 0.0127381 0.6764706 GO:2001234 GO:BP negative regulation of apoptotic signaling pathway 16307 27881 GO:00099…. query_1 TRUE 0.0077550 62 9028 47 0.0052060 0.7580645 GO:0035148 GO:BP tube formation 16307 9373 GO:00352…. query_1 TRUE 0.0077716 41 9028 33 0.0036553 0.8048780 GO:0035329 GO:BP hippo signaling 16307 9506 GO:0035556 query_1 TRUE 0.0077716 41 9028 33 0.0036553 0.8048780 GO:0060236 GO:BP regulation of mitotic spindle organization 16307 15384 GO:00070…. query_1 TRUE 0.0080637 44 9028 35 0.0038768 0.7954545 GO:2001244 GO:BP positive regulation of intrinsic apoptotic signaling pathway 16307 27891 GO:00971…. query_1 TRUE 0.0080637 162 9028 110 0.0121843 0.6790123 GO:0032872 GO:BP regulation of stress-activated MAPK cascade 16307 8337 GO:00434…. query_1 TRUE 0.0081194 56 9028 43 0.0047630 0.7678571 GO:0038202 GO:BP TORC1 signaling 16307 10373 GO:0031929 query_1 TRUE 0.0081194 56 9028 43 0.0047630 0.7678571 GO:0009166 GO:BP nucleotide catabolic process 16307 3424 GO:00091…. query_1 TRUE 0.0082126 47 9028 37 0.0040984 0.7872340 GO:0043536 GO:BP positive regulation of blood vessel endothelial cell migration 16307 11409 GO:00105…. query_1 TRUE 0.0082218 53 9028 41 0.0045414 0.7735849 GO:0031060 GO:BP regulation of histone methylation 16307 7433 GO:00165…. query_1 TRUE 0.0086865 98 9028 70 0.0077537 0.7142857 GO:0034440 GO:BP lipid oxidation 16307 9137 GO:0030258 query_1 TRUE 0.0086865 98 9028 70 0.0077537 0.7142857 GO:0006304 GO:BP DNA modification 16307 2169 GO:00062…. query_1 TRUE 0.0089598 31 9028 26 0.0028799 0.8387097 GO:0090169 GO:BP regulation of spindle assembly 16307 19221 GO:00512…. query_1 TRUE 0.0091524 12 9028 12 0.0013292 1.0000000 GO:0007000 GO:BP nucleolus organization 16307 2690 GO:0006997 query_1 TRUE 0.0091524 12 9028 12 0.0013292 1.0000000 GO:0006388 GO:BP tRNA splicing, via endonucleolytic cleavage and ligation 16307 2215 GO:00003…. query_1 TRUE 0.0091524 12 9028 12 0.0013292 1.0000000 GO:0009147 GO:BP pyrimidine nucleoside triphosphate metabolic process 16307 3406 GO:0009141 query_1 TRUE 0.0091524 12 9028 12 0.0013292 1.0000000 GO:2000105 GO:BP positive regulation of DNA-templated DNA replication 16307 26864 GO:00062…. query_1 TRUE 0.0091524 12 9028 12 0.0013292 1.0000000 GO:1904867 GO:BP protein localization to Cajal body 16307 25478 GO:1903405 query_1 TRUE 0.0091524 12 9028 12 0.0013292 1.0000000 GO:0070202 GO:BP regulation of establishment of protein localization to chromosome 16307 17026 GO:00701…. query_1 TRUE 0.0091524 12 9028 12 0.0013292 1.0000000 GO:1903405 GO:BP protein localization to nuclear body 16307 24202 GO:1990173 query_1 TRUE 0.0091524 12 9028 12 0.0013292 1.0000000 GO:0046831 GO:BP regulation of RNA export from nucleus 16307 13184 GO:00064…. query_1 TRUE 0.0091524 12 9028 12 0.0013292 1.0000000 GO:0090232 GO:BP positive regulation of spindle checkpoint 16307 19277 GO:00315…. query_1 TRUE 0.0091524 12 9028 12 0.0013292 1.0000000 GO:0090267 GO:BP positive regulation of mitotic cell cycle spindle assembly checkpoint 16307 19310 GO:00070…. query_1 TRUE 0.0092283 70 9028 52 0.0057599 0.7428571 GO:1903533 GO:BP regulation of protein targeting 16307 24313 GO:00066…. query_1 TRUE 0.0092468 84 9028 61 0.0067568 0.7261905 GO:0009185 GO:BP ribonucleoside diphosphate metabolic process 16307 3443 GO:0009132 query_1 TRUE 0.0094789 24 9028 21 0.0023261 0.8750000 GO:0032801 GO:BP receptor catabolic process 16307 8298 GO:00090…. query_1 TRUE 0.0094789 24 9028 21 0.0023261 0.8750000 GO:0070861 GO:BP regulation of protein exit from endoplasmic reticulum 16307 17402 GO:00325…. query_1 TRUE 0.0094789 24 9028 21 0.0023261 0.8750000 GO:0042059 GO:BP negative regulation of epidermal growth factor receptor signaling pathway 16307 10568 GO:00071…. query_1 TRUE 0.0094789 24 9028 21 0.0023261 0.8750000 GO:0009126 GO:BP purine nucleoside monophosphate metabolic process 16307 3385 GO:0009123 query_1 TRUE 0.0095569 135 9028 93 0.0103013 0.6888889 GO:0061572 GO:BP actin filament bundle organization 16307 16587 GO:0007015 query_1 TRUE 0.0096205 67 9028 50 0.0055383 0.7462687 GO:0036473 GO:BP cell death in response to oxidative stress 16307 10203 GO:00082…. query_1 TRUE 0.0096205 67 9028 50 0.0055383 0.7462687 GO:1901292 GO:BP nucleoside phosphate catabolic process 16307 22438 GO:00067…. query_1 TRUE 0.0097546 111 9028 78 0.0086398 0.7027027 GO:2001236 GO:BP regulation of extrinsic apoptotic signaling pathway 16307 27883 GO:00971…. query_1 TRUE 0.0097904 81 9028 59 0.0065352 0.7283951 GO:0030512 GO:BP negative regulation of transforming growth factor beta receptor signaling pathway 16307 7229 GO:00071…. query_1 TRUE 0.0098221 34 9028 28 0.0031015 0.8235294 GO:1900087 GO:BP positive regulation of G1/S transition of mitotic cell cycle 16307 21400 GO:00000…. query_1 TRUE 0.0098221 34 9028 28 0.0031015 0.8235294 GO:0097300 GO:BP programmed necrotic cell death 16307 19759 GO:00125…. query_1 TRUE 0.0104293 61 9028 46 0.0050953 0.7540984 GO:0033143 GO:BP regulation of intracellular steroid hormone receptor signaling pathway 16307 8527 GO:00099…. query_1 TRUE 0.0107923 58 9028 44 0.0048737 0.7586207 GO:0048278 GO:BP vesicle docking 16307 13440 GO:00161…. query_1 TRUE 0.0110758 40 9028 32 0.0035445 0.8000000 GO:1903573 GO:BP negative regulation of response to endoplasmic reticulum stress 16307 24351 GO:00349…. query_1 TRUE 0.0110758 40 9028 32 0.0035445 0.8000000 GO:1903214 GO:BP regulation of protein targeting to mitochondrion 16307 24039 GO:00066…. query_1 TRUE 0.0111266 20 9028 18 0.0019938 0.9000000 GO:2000434 GO:BP regulation of protein neddylation 16307 27179 GO:00451…. query_1 TRUE 0.0111266 20 9028 18 0.0019938 0.9000000 GO:0009156 GO:BP ribonucleoside monophosphate biosynthetic process 16307 3415 GO:00091…. query_1 TRUE 0.0111266 20 9028 18 0.0019938 0.9000000 GO:0008334 GO:BP histone mRNA metabolic process 16307 3255 GO:0016071 query_1 TRUE 0.0111266 20 9028 18 0.0019938 0.9000000 GO:0036003 GO:BP positive regulation of transcription from RNA polymerase II promoter in response to stress 16307 9949 GO:00436…. query_1 TRUE 0.0113324 43 9028 34 0.0037661 0.7906977 GO:2000059 GO:BP negative regulation of ubiquitin-dependent protein catabolic process 16307 26819 GO:00065…. query_1 TRUE 0.0114202 49 9028 38 0.0042091 0.7755102 GO:0034605 GO:BP cellular response to heat 16307 9190 GO:00094…. query_1 TRUE 0.0114362 46 9028 36 0.0039876 0.7826087 GO:1903747 GO:BP regulation of establishment of protein localization to mitochondrion 16307 24507 GO:00702…. query_1 TRUE 0.0115189 27 9028 23 0.0025476 0.8518519 GO:0070199 GO:BP establishment of protein localization to chromosome 16307 17023 GO:00345…. query_1 TRUE 0.0115189 27 9028 23 0.0025476 0.8518519 GO:0007064 GO:BP mitotic sister chromatid cohesion 16307 2737 GO:00000…. query_1 TRUE 0.0115189 27 9028 23 0.0025476 0.8518519 GO:0042307 GO:BP positive regulation of protein import into nucleus 16307 10708 GO:00066…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0033750 GO:BP ribosome localization 16307 8843 GO:0051640 query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0048308 GO:BP organelle inheritance 16307 13466 GO:0006996 query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0000054 GO:BP ribosomal subunit export from nucleus 16307 22 GO:00315…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0048313 GO:BP Golgi inheritance 16307 13470 GO:00070…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0034497 GO:BP protein localization to phagophore assembly site 16307 9169 GO:00000…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0006490 GO:BP oligosaccharide-lipid intermediate biosynthetic process 16307 2288 GO:00442…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:2000232 GO:BP regulation of rRNA processing 16307 26985 GO:00063…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0036499 GO:BP PERK-mediated unfolded protein response 16307 10224 GO:00069…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0006221 GO:BP pyrimidine nucleotide biosynthetic process 16307 2102 GO:00062…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0060339 GO:BP negative regulation of type I interferon-mediated signaling pathway 16307 15478 GO:00019…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0015936 GO:BP coenzyme A metabolic process 16307 5173 GO:00091…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0042795 GO:BP snRNA transcription by RNA polymerase II 16307 11007 GO:00063…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:1903358 GO:BP regulation of Golgi organization 16307 24160 GO:00070…. query_1 TRUE 0.0115216 16 9028 15 0.0016615 0.9375000 GO:0080009 GO:BP mRNA methylation 16307 18896 GO:00015…. query_1 TRUE 0.0115715 196 9028 130 0.0143996 0.6632653 GO:0071375 GO:BP cellular response to peptide hormone stimulus 16307 17699 GO:00328…. query_1 TRUE 0.0115828 274 9028 177 0.0196057 0.6459854 GO:0030111 GO:BP regulation of Wnt signaling pathway 16307 7080 GO:00099…. query_1 TRUE 0.0117505 201 9028 133 0.0147319 0.6616915 GO:0009144 GO:BP purine nucleoside triphosphate metabolic process 16307 3403 GO:0009141 query_1 TRUE 0.0120902 1383 9028 820 0.0908285 0.5929140 GO:0023056 GO:BP positive regulation of signaling 16307 7038 GO:00230…. query_1 TRUE 0.0120902 343 9028 218 0.0241471 0.6355685 GO:0198738 GO:BP cell-cell signaling by wnt 16307 21329 GO:0007267 query_1 TRUE 0.0126600 80 9028 58 0.0064245 0.7250000 GO:0043473 GO:BP pigmentation 16307 11370 GO:0008150 query_1 TRUE 0.0130365 30 9028 25 0.0027692 0.8333333 GO:0032366 GO:BP intracellular sterol transport 16307 7981 GO:00159…. query_1 TRUE 0.0130365 30 9028 25 0.0027692 0.8333333 GO:0070266 GO:BP necroptotic process 16307 17071 GO:0097300 query_1 TRUE 0.0134897 77 9028 56 0.0062029 0.7272727 GO:0032091 GO:BP negative regulation of protein binding 16307 7807 GO:00433…. query_1 TRUE 0.0134897 88 9028 63 0.0069783 0.7159091 GO:0032465 GO:BP regulation of cytokinesis 16307 8041 GO:00009…. query_1 TRUE 0.0136260 233 9028 152 0.0168365 0.6523605 GO:0051258 GO:BP protein polymerization 16307 14457 GO:0065003 query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:0009167 GO:BP purine ribonucleoside monophosphate metabolic process 16307 3425 GO:00091…. query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:0048207 GO:BP vesicle targeting, rough ER to cis-Golgi 16307 13401 GO:00068…. query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:1900370 GO:BP positive regulation of post-transcriptional gene silencing by RNA 16307 21666 GO:00351…. query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:1901658 GO:BP glycosyl compound catabolic process 16307 22748 GO:19011…. query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:0048208 GO:BP COPII vesicle coating 16307 13402 GO:00069…. query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:0006658 GO:BP phosphatidylserine metabolic process 16307 2434 GO:00065…. query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:0060155 GO:BP platelet dense granule organization 16307 15320 GO:0033363 query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:2000001 GO:BP regulation of DNA damage checkpoint 16307 26763 GO:00000…. query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:0045048 GO:BP protein insertion into ER membrane 16307 12010 GO:00070…. query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:0046825 GO:BP regulation of protein export from nucleus 16307 13178 GO:00066…. query_1 TRUE 0.0143987 23 9028 20 0.0022153 0.8695652 GO:0060148 GO:BP positive regulation of post-transcriptional gene silencing 16307 15315 GO:00164…. query_1 TRUE 0.0146431 1736 9028 1020 0.1129818 0.5875576 GO:0010033 GO:BP response to organic substance 16307 3939 GO:0042221 query_1 TRUE 0.0147826 240 9028 156 0.0172796 0.6500000 GO:1901653 GO:BP cellular response to peptide 16307 22743 GO:00714…. query_1 TRUE 0.0149456 339 9028 215 0.0238148 0.6342183 GO:0016055 GO:BP Wnt signaling pathway 16307 5243 GO:01987…. query_1 TRUE 0.0149456 36 9028 29 0.0032122 0.8055556 GO:0043001 GO:BP Golgi to plasma membrane protein transport 16307 11115 GO:00068…. query_1 TRUE 0.0149456 36 9028 29 0.0032122 0.8055556 GO:0035794 GO:BP positive regulation of mitochondrial membrane permeability 16307 9808 GO:00469…. query_1 TRUE 0.0149456 36 9028 29 0.0032122 0.8055556 GO:0031062 GO:BP positive regulation of histone methylation 16307 7435 GO:00165…. query_1 TRUE 0.0149456 36 9028 29 0.0032122 0.8055556 GO:0032205 GO:BP negative regulation of telomere maintenance 16307 7858 GO:00007…. query_1 TRUE 0.0149456 36 9028 29 0.0032122 0.8055556 GO:0035305 GO:BP negative regulation of dephosphorylation 16307 9489 GO:00163…. query_1 TRUE 0.0153351 82 9028 59 0.0065352 0.7195122 GO:0033209 GO:BP tumor necrosis factor-mediated signaling pathway 16307 8549 GO:00192…. query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0000338 GO:BP protein deneddylation 16307 103 GO:0070646 query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0051987 GO:BP positive regulation of attachment of spindle microtubules to kinetochore 16307 14926 GO:00086…. query_1 TRUE 0.0153495 48 9028 37 0.0040984 0.7708333 GO:0032007 GO:BP negative regulation of TOR signaling 16307 7758 GO:00319…. query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0015937 GO:BP coenzyme A biosynthetic process 16307 5174 GO:00091…. query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0042276 GO:BP error-prone translesion synthesis 16307 10701 GO:0019985 query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0036295 GO:BP cellular response to increased oxygen levels 16307 10124 GO:00362…. query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:1904869 GO:BP regulation of protein localization to Cajal body 16307 25480 GO:19001…. query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:1902969 GO:BP mitotic DNA replication 16307 23840 GO:00332…. query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:1904871 GO:BP positive regulation of protein localization to Cajal body 16307 25482 GO:19001…. query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0006825 GO:BP copper ion transport 16307 2570 GO:0000041 query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0034616 GO:BP response to laminar fluid shear stress 16307 9197 GO:0034405 query_1 TRUE 0.0153495 48 9028 37 0.0040984 0.7708333 GO:0031146 GO:BP SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 16307 7487 GO:0043161 query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0070213 GO:BP protein auto-ADP-ribosylation 16307 17032 GO:0043687 query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0043558 GO:BP regulation of translational initiation in response to stress 16307 11425 GO:00064…. query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0070203 GO:BP regulation of establishment of protein localization to telomere 16307 17027 GO:00702…. query_1 TRUE 0.0153495 11 9028 11 0.0012184 1.0000000 GO:0051127 GO:BP positive regulation of actin nucleation 16307 14356 GO:00450…. query_1 TRUE 0.0154459 42 9028 33 0.0036553 0.7857143 GO:0060966 GO:BP regulation of gene silencing by RNA 16307 16062 GO:00104…. query_1 TRUE 0.0154459 42 9028 33 0.0036553 0.7857143 GO:1902653 GO:BP secondary alcohol biosynthetic process 16307 23587 GO:00461…. query_1 TRUE 0.0154459 42 9028 33 0.0036553 0.7857143 GO:0034205 GO:BP amyloid-beta formation 16307 8990 GO:00429…. query_1 TRUE 0.0154459 42 9028 33 0.0036553 0.7857143 GO:0090199 GO:BP regulation of release of cytochrome c from mitochondria 16307 19247 GO:00018…. query_1 TRUE 0.0154459 42 9028 33 0.0036553 0.7857143 GO:0006695 GO:BP cholesterol biosynthetic process 16307 2470 GO:00082…. query_1 TRUE 0.0162033 98 9028 69 0.0076429 0.7040816 GO:0009132 GO:BP nucleoside diphosphate metabolic process 16307 3391 GO:0006753 query_1 TRUE 0.0166557 204 9028 134 0.0148427 0.6568627 GO:0010632 GO:BP regulation of epithelial cell migration 16307 4396 GO:00106…. query_1 TRUE 0.0168518 26 9028 22 0.0024369 0.8461538 GO:0006783 GO:BP heme biosynthetic process 16307 2538 GO:00067…. query_1 TRUE 0.0168518 26 9028 22 0.0024369 0.8461538 GO:0008053 GO:BP mitochondrial fusion 16307 3194 GO:00070…. query_1 TRUE 0.0168518 26 9028 22 0.0024369 0.8461538 GO:0030866 GO:BP cortical actin cytoskeleton organization 16307 7349 GO:00300…. query_1 TRUE 0.0168518 26 9028 22 0.0024369 0.8461538 GO:0035066 GO:BP positive regulation of histone acetylation 16307 9313 GO:00165…. query_1 TRUE 0.0168518 26 9028 22 0.0024369 0.8461538 GO:0072529 GO:BP pyrimidine-containing compound catabolic process 16307 18536 GO:00442…. query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0000963 GO:BP mitochondrial RNA processing 16307 288 GO:00009…. query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0035455 GO:BP response to interferon-alpha 16307 9576 GO:0034097 query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0150105 GO:BP protein localization to cell-cell junction 16307 21240 GO:1902414 query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0051571 GO:BP positive regulation of histone H3-K4 methylation 16307 14664 GO:00310…. query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0043555 GO:BP regulation of translation in response to stress 16307 11422 GO:00064…. query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0051457 GO:BP maintenance of protein location in nucleus 16307 14580 GO:00345…. query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0007042 GO:BP lysosomal lumen acidification 16307 2721 GO:00070…. query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0045947 GO:BP negative regulation of translational initiation 16307 12515 GO:00064…. query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0006613 GO:BP cotranslational protein targeting to membrane 16307 2395 GO:0006612 query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:1904666 GO:BP regulation of ubiquitin protein ligase activity 16307 25305 GO:0051438 query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0032401 GO:BP establishment of melanosome localization 16307 8006 GO:00324…. query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0043628 GO:BP regulatory ncRNA 3’-end processing 16307 11470 GO:0031123 query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0051905 GO:BP establishment of pigment granule localization 16307 14862 GO:00516…. query_1 TRUE 0.0168719 19 9028 17 0.0018830 0.8947368 GO:0046782 GO:BP regulation of viral transcription 16307 13157 GO:00190…. query_1 TRUE 0.0177182 196 9028 129 0.0142889 0.6581633 GO:0044242 GO:BP cellular lipid catabolic process 16307 11641 GO:00160…. query_1 TRUE 0.0179778 124 9028 85 0.0094152 0.6854839 GO:0046434 GO:BP organophosphate catabolic process 16307 12928 GO:00196…. query_1 TRUE 0.0181081 261 9028 168 0.0186088 0.6436782 GO:0010631 GO:BP epithelial cell migration 16307 4395 GO:00016…. query_1 TRUE 0.0181136 137 9028 93 0.0103013 0.6788321 GO:0043409 GO:BP negative regulation of MAPK cascade 16307 11324 GO:00001…. query_1 TRUE 0.0181253 59 9028 44 0.0048737 0.7457627 GO:1901657 GO:BP glycosyl compound metabolic process 16307 22747 GO:1901135 query_1 TRUE 0.0182352 15 9028 14 0.0015507 0.9333333 GO:1904814 GO:BP regulation of protein localization to chromosome, telomeric region 16307 25432 GO:00328…. query_1 TRUE 0.0182352 15 9028 14 0.0015507 0.9333333 GO:0001732 GO:BP formation of cytoplasmic translation initiation complex 16307 432 GO:00021…. query_1 TRUE 0.0182352 231 9028 150 0.0166150 0.6493506 GO:0043434 GO:BP response to peptide hormone 16307 11338 GO:00097…. query_1 TRUE 0.0182352 15 9028 14 0.0015507 0.9333333 GO:0043328 GO:BP protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 16307 11282 GO:00068…. query_1 TRUE 0.0182352 15 9028 14 0.0015507 0.9333333 GO:0045842 GO:BP positive regulation of mitotic metaphase/anaphase transition 16307 12434 GO:00070…. query_1 TRUE 0.0182352 15 9028 14 0.0015507 0.9333333 GO:1902018 GO:BP negative regulation of cilium assembly 16307 23085 GO:00602…. query_1 TRUE 0.0182352 15 9028 14 0.0015507 0.9333333 GO:1902101 GO:BP positive regulation of metaphase/anaphase transition of cell cycle 16307 23155 GO:00447…. query_1 TRUE 0.0182352 15 9028 14 0.0015507 0.9333333 GO:0035067 GO:BP negative regulation of histone acetylation 16307 9314 GO:00165…. query_1 TRUE 0.0182352 15 9028 14 0.0015507 0.9333333 GO:0006620 GO:BP post-translational protein targeting to endoplasmic reticulum membrane 16307 2401 GO:00066…. query_1 TRUE 0.0182352 15 9028 14 0.0015507 0.9333333 GO:0090110 GO:BP COPII-coated vesicle cargo loading 16307 19170 GO:00354…. query_1 TRUE 0.0182352 15 9028 14 0.0015507 0.9333333 GO:0031573 GO:BP mitotic intra-S DNA damage checkpoint signaling 16307 7664 GO:0044773 query_1 TRUE 0.0182404 722 9028 438 0.0485157 0.6066482 GO:0030029 GO:BP actin filament-based process 16307 7050 GO:0009987 query_1 TRUE 0.0184589 92 9028 65 0.0071998 0.7065217 GO:0002262 GO:BP myeloid cell homeostasis 16307 819 GO:00023…. query_1 TRUE 0.0185350 29 9028 24 0.0026584 0.8275862 GO:0140718 GO:BP facultative heterochromatin formation 16307 21102 GO:0031507 query_1 TRUE 0.0187708 56 9028 42 0.0046522 0.7500000 GO:0072175 GO:BP epithelial tube formation 16307 18307 GO:00351…. query_1 TRUE 0.0190823 310 9028 197 0.0218210 0.6354839 GO:1902903 GO:BP regulation of supramolecular fiber organization 16307 23782 GO:00511…. query_1 TRUE 0.0191847 70 9028 51 0.0056491 0.7285714 GO:0070897 GO:BP transcription preinitiation complex assembly 16307 17421 GO:00063…. query_1 TRUE 0.0191868 81 9028 58 0.0064245 0.7160494 GO:0090398 GO:BP cellular senescence 16307 19428 GO:00335…. query_1 TRUE 0.0191982 198 9028 130 0.0143996 0.6565657 GO:0009205 GO:BP purine ribonucleoside triphosphate metabolic process 16307 3463 GO:00091…. query_1 TRUE 0.0192629 263 9028 169 0.0187195 0.6425856 GO:0090132 GO:BP epithelium migration 16307 19189 GO:0090130 query_1 TRUE 0.0195159 170 9028 113 0.0125166 0.6647059 GO:0030258 GO:BP lipid modification 16307 7146 GO:0044255 query_1 TRUE 0.0197602 113 9028 78 0.0086398 0.6902655 GO:0030177 GO:BP positive regulation of Wnt signaling pathway 16307 7096 GO:00099…. query_1 TRUE 0.0198782 32 9028 26 0.0028799 0.8125000 GO:0060338 GO:BP regulation of type I interferon-mediated signaling pathway 16307 15477 GO:00019…. query_1 TRUE 0.0201484 50 9028 38 0.0042091 0.7600000 GO:0035196 GO:BP miRNA processing 16307 9414 GO:0070918 query_1 TRUE 0.0202256 126 9028 86 0.0095259 0.6825397 GO:0016052 GO:BP carbohydrate catabolic process 16307 5240 GO:00059…. query_1 TRUE 0.0205326 78 9028 56 0.0062029 0.7179487 GO:0007044 GO:BP cell-substrate junction assembly 16307 2723 GO:00343…. query_1 TRUE 0.0207379 35 9028 28 0.0031015 0.8000000 GO:1902686 GO:BP mitochondrial outer membrane permeabilization involved in programmed cell death 16307 23609 GO:00125…. query_1 TRUE 0.0210905 44 9028 34 0.0037661 0.7727273 GO:0034661 GO:BP ncRNA catabolic process 16307 9223 GO:00064…. query_1 TRUE 0.0211542 38 9028 30 0.0033230 0.7894737 GO:1902275 GO:BP regulation of chromatin organization 16307 23312 GO:00063…. query_1 TRUE 0.0211542 38 9028 30 0.0033230 0.7894737 GO:0006739 GO:BP NADP metabolic process 16307 2506 GO:00061…. query_1 TRUE 0.0211742 210 9028 137 0.0151750 0.6523810 GO:0060828 GO:BP regulation of canonical Wnt signaling pathway 16307 15935 GO:00301…. query_1 TRUE 0.0211778 22 9028 19 0.0021046 0.8636364 GO:2000637 GO:BP positive regulation of miRNA-mediated gene silencing 16307 27355 GO:00351…. query_1 TRUE 0.0211778 22 9028 19 0.0021046 0.8636364 GO:1902410 GO:BP mitotic cytokinetic process 16307 23418 GO:00002…. query_1 TRUE 0.0211778 22 9028 19 0.0021046 0.8636364 GO:0032069 GO:BP regulation of nuclease activity 16307 7787 GO:00513…. query_1 TRUE 0.0211778 22 9028 19 0.0021046 0.8636364 GO:0009112 GO:BP nucleobase metabolic process 16307 3373 GO:00550…. query_1 TRUE 0.0211778 22 9028 19 0.0021046 0.8636364 GO:0043574 GO:BP peroxisomal transport 16307 11435 GO:0046907 query_1 TRUE 0.0211778 22 9028 19 0.0021046 0.8636364 GO:0008299 GO:BP isoprenoid biosynthetic process 16307 3248 GO:00067…. query_1 TRUE 0.0211778 22 9028 19 0.0021046 0.8636364 GO:1904263 GO:BP positive regulation of TORC1 signaling 16307 24945 GO:00320…. query_1 TRUE 0.0211991 86 9028 61 0.0067568 0.7093023 GO:0048525 GO:BP negative regulation of viral process 16307 13629 GO:00160…. query_1 TRUE 0.0215555 102 9028 71 0.0078644 0.6960784 GO:0043244 GO:BP regulation of protein-containing complex disassembly 16307 11227 GO:00329…. query_1 TRUE 0.0224859 159 9028 106 0.0117412 0.6666667 GO:0030100 GO:BP regulation of endocytosis 16307 7076 GO:00068…. query_1 TRUE 0.0229531 164 9028 109 0.0120735 0.6646341 GO:0007623 GO:BP circadian rhythm 16307 3168 GO:0048511 query_1 TRUE 0.0237976 133 9028 90 0.0099690 0.6766917 GO:0051302 GO:BP regulation of cell division 16307 14485 GO:00507…. query_1 TRUE 0.0239801 495 9028 305 0.0337838 0.6161616 GO:0032787 GO:BP monocarboxylic acid metabolic process 16307 8290 GO:0019752 query_1 TRUE 0.0241103 1380 9028 814 0.0901639 0.5898551 GO:0010647 GO:BP positive regulation of cell communication 16307 4411 GO:00071…. query_1 TRUE 0.0246389 244 9028 157 0.0173903 0.6434426 GO:0051091 GO:BP positive regulation of DNA-binding transcription factor activity 16307 14329 GO:00440…. query_1 TRUE 0.0246389 80 9028 57 0.0063137 0.7125000 GO:0043535 GO:BP regulation of blood vessel endothelial cell migration 16307 11408 GO:00105…. query_1 TRUE 0.0247092 25 9028 21 0.0023261 0.8400000 GO:0051569 GO:BP regulation of histone H3-K4 methylation 16307 14662 GO:00310…. query_1 TRUE 0.0251333 55 9028 41 0.0045414 0.7454545 GO:0061951 GO:BP establishment of protein localization to plasma membrane 16307 16777 GO:00726…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:1903897 GO:BP regulation of PERK-mediated unfolded protein response 16307 24627 GO:00364…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:2000615 GO:BP regulation of histone H3-K9 acetylation 16307 27333 GO:00350…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:1904851 GO:BP positive regulation of establishment of protein localization to telomere 16307 25466 GO:00702…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0034427 GO:BP nuclear-transcribed mRNA catabolic process, exonucleolytic, 3’-5’ 16307 9131 GO:0000291 query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:1904896 GO:BP ESCRT complex disassembly 16307 25507 GO:0032984 query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:1904903 GO:BP ESCRT III complex disassembly 16307 25514 GO:1904896 query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0031118 GO:BP rRNA pseudouridine synthesis 16307 7464 GO:00001…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0031293 GO:BP membrane protein intracellular domain proteolysis 16307 7540 GO:0033619 query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0045050 GO:BP protein insertion into ER membrane by stop-transfer membrane-anchor sequence 16307 12012 GO:0045048 query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0035435 GO:BP phosphate ion transmembrane transport 16307 9567 GO:00068…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0006054 GO:BP N-acetylneuraminate metabolic process 16307 1971 GO:00060…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0033523 GO:BP histone H2B ubiquitination 16307 8742 GO:0016574 query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0031125 GO:BP rRNA 3’-end processing 16307 7471 GO:00063…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0043970 GO:BP histone H3-K9 acetylation 16307 11554 GO:00439…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0036490 GO:BP regulation of translation in response to endoplasmic reticulum stress 16307 10215 GO:00349…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:1903069 GO:BP regulation of ER-associated ubiquitin-dependent protein catabolic process 16307 23937 GO:00304…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0042532 GO:BP negative regulation of tyrosine phosphorylation of STAT protein 16307 10858 GO:00072…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0006265 GO:BP DNA topological change 16307 2138 GO:00062…. query_1 TRUE 0.0256602 10 9028 10 0.0011077 1.0000000 GO:0071028 GO:BP nuclear mRNA surveillance 16307 17495 GO:00009…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0042659 GO:BP regulation of cell fate specification 16307 10905 GO:00017…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0006625 GO:BP protein targeting to peroxisome 16307 2406 GO:00066…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0050686 GO:BP negative regulation of mRNA processing 16307 14044 GO:00063…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0072663 GO:BP establishment of protein localization to peroxisome 16307 18589 GO:00725…. query_1 TRUE 0.0256839 52 9028 39 0.0043199 0.7500000 GO:0070059 GO:BP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 16307 16933 GO:00349…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0051904 GO:BP pigment granule transport 16307 14861 GO:00068…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0044154 GO:BP histone H3-K14 acetylation 16307 11627 GO:0043966 query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0006379 GO:BP mRNA cleavage 16307 2209 GO:00160…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0046931 GO:BP pore complex assembly 16307 13245 GO:0065003 query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0001919 GO:BP regulation of receptor recycling 16307 556 GO:00018…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0006098 GO:BP pentose-phosphate shunt 16307 2010 GO:00067…. query_1 TRUE 0.0256839 52 9028 39 0.0043199 0.7500000 GO:0043407 GO:BP negative regulation of MAP kinase activity 16307 11322 GO:00434…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0032402 GO:BP melanosome transport 16307 8007 GO:00324…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0019081 GO:BP viral translation 16307 5900 GO:00160…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0006977 GO:BP DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 16307 2676 GO:00303…. query_1 TRUE 0.0256839 18 9028 16 0.0017723 0.8888889 GO:0072662 GO:BP protein localization to peroxisome 16307 18588 GO:00070…. query_1 TRUE 0.0265055 28 9028 23 0.0025476 0.8214286 GO:0060765 GO:BP regulation of androgen receptor signaling pathway 16307 15877 GO:00305…. query_1 TRUE 0.0265055 211 9028 137 0.0151750 0.6492891 GO:0016054 GO:BP organic acid catabolic process 16307 5242 GO:00060…. query_1 TRUE 0.0265055 28 9028 23 0.0025476 0.8214286 GO:0045116 GO:BP protein neddylation 16307 12050 GO:0032446 query_1 TRUE 0.0265055 28 9028 23 0.0025476 0.8214286 GO:0061647 GO:BP histone H3-K9 modification 16307 16627 GO:0016570 query_1 TRUE 0.0276638 46 9028 35 0.0038768 0.7608696 GO:0001838 GO:BP embryonic epithelial tube formation 16307 516 GO:00163…. query_1 TRUE 0.0276638 46 9028 35 0.0038768 0.7608696 GO:0016126 GO:BP sterol biosynthetic process 16307 5301 GO:00066…. query_1 TRUE 0.0276638 46 9028 35 0.0038768 0.7608696 GO:0010718 GO:BP positive regulation of epithelial to mesenchymal transition 16307 4469 GO:00018…. query_1 TRUE 0.0277347 74 9028 53 0.0058706 0.7162162 GO:2001021 GO:BP negative regulation of response to DNA damage stimulus 16307 27715 GO:00069…. query_1 TRUE 0.0280436 243 9028 156 0.0172796 0.6419753 GO:0051056 GO:BP regulation of small GTPase mediated signal transduction 16307 14309 GO:00072…. query_1 TRUE 0.0281930 106 9028 73 0.0080860 0.6886792 GO:0035303 GO:BP regulation of dephosphorylation 16307 9487 GO:00163…. query_1 TRUE 0.0283851 43 9028 33 0.0036553 0.7674419 GO:0006414 GO:BP translational elongation 16307 2236 GO:00064…. query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:0072393 GO:BP microtubule anchoring at microtubule organizing center 16307 18492 GO:0034453 query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:0071501 GO:BP cellular response to sterol depletion 16307 17810 GO:00069…. query_1 TRUE 0.0285972 34 9028 27 0.0029907 0.7941176 GO:0070316 GO:BP regulation of G0 to G1 transition 16307 17101 GO:00105…. query_1 TRUE 0.0285972 34 9028 27 0.0029907 0.7941176 GO:0044273 GO:BP sulfur compound catabolic process 16307 11658 GO:00067…. query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:0006878 GO:BP cellular copper ion homeostasis 16307 2606 GO:00469…. query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:0032239 GO:BP regulation of nucleobase-containing compound transport 16307 7886 GO:00159…. query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:2000104 GO:BP negative regulation of DNA-templated DNA replication 16307 26863 GO:00062…. query_1 TRUE 0.0285972 40 9028 31 0.0034338 0.7750000 GO:0060147 GO:BP regulation of post-transcriptional gene silencing 16307 15314 GO:00104…. query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:0098787 GO:BP mRNA cleavage involved in mRNA processing 16307 20084 GO:00063…. query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:1990173 GO:BP protein localization to nucleoplasm 16307 26486 GO:0034504 query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:0042994 GO:BP cytoplasmic sequestering of transcription factor 16307 11111 GO:00434…. query_1 TRUE 0.0285972 34 9028 27 0.0029907 0.7941176 GO:0043516 GO:BP regulation of DNA damage response, signal transduction by p53 class mediator 16307 11398 GO:00303…. query_1 TRUE 0.0285972 40 9028 31 0.0034338 0.7750000 GO:1905710 GO:BP positive regulation of membrane permeability 16307 26221 GO:0090559 query_1 TRUE 0.0285972 40 9028 31 0.0034338 0.7750000 GO:1900368 GO:BP regulation of post-transcriptional gene silencing by RNA 16307 21664 GO:00351…. query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:0016078 GO:BP tRNA catabolic process 16307 5262 GO:00063…. query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:1900102 GO:BP negative regulation of endoplasmic reticulum unfolded protein response 16307 21414 GO:00099…. query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:0046753 GO:BP non-lytic viral release 16307 13141 GO:0019076 query_1 TRUE 0.0285972 14 9028 13 0.0014400 0.9285714 GO:0090503 GO:BP RNA phosphodiester bond hydrolysis, exonucleolytic 16307 19484 GO:0090501 query_1 TRUE 0.0285972 40 9028 31 0.0034338 0.7750000 GO:1901661 GO:BP quinone metabolic process 16307 22751 GO:0042180 query_1 TRUE 0.0286944 37 9028 29 0.0032122 0.7837838 GO:0070536 GO:BP protein K63-linked deubiquitination 16307 17220 GO:0016579 query_1 TRUE 0.0305766 129 9028 87 0.0096367 0.6744186 GO:0051053 GO:BP negative regulation of DNA metabolic process 16307 14306 GO:00062…. query_1 TRUE 0.0306675 220 9028 142 0.0157288 0.6454545 GO:0032886 GO:BP regulation of microtubule-based process 16307 8351 GO:00070…. query_1 TRUE 0.0307739 57 9028 42 0.0046522 0.7368421 GO:0046364 GO:BP monosaccharide biosynthetic process 16307 12875 GO:00059…. query_1 TRUE 0.0307739 57 9028 42 0.0046522 0.7368421 GO:1900407 GO:BP regulation of cellular response to oxidative stress 16307 21686 GO:00345…. query_1 TRUE 0.0313333 21 9028 18 0.0019938 0.8571429 GO:1902774 GO:BP late endosome to lysosome transport 16307 23670 GO:0007041 query_1 TRUE 0.0313333 21 9028 18 0.0019938 0.8571429 GO:0045736 GO:BP negative regulation of cyclin-dependent protein serine/threonine kinase activity 16307 12350 GO:00000…. query_1 TRUE 0.0313333 21 9028 18 0.0019938 0.8571429 GO:0016075 GO:BP rRNA catabolic process 16307 5259 GO:00160…. query_1 TRUE 0.0313333 21 9028 18 0.0019938 0.8571429 GO:1904030 GO:BP negative regulation of cyclin-dependent protein kinase activity 16307 24743 GO:00064…. query_1 TRUE 0.0314031 134 9028 90 0.0099690 0.6716418 GO:0060759 GO:BP regulation of response to cytokine stimulus 16307 15871 GO:00340…. query_1 TRUE 0.0328269 100 9028 69 0.0076429 0.6900000 GO:0009266 GO:BP response to temperature stimulus 16307 3523 GO:0009628 query_1 TRUE 0.0330717 779 9028 468 0.0518387 0.6007702 GO:0051336 GO:BP regulation of hydrolase activity 16307 14515 GO:0050790 query_1 TRUE 0.0333804 207 9028 134 0.0148427 0.6473430 GO:0046395 GO:BP carboxylic acid catabolic process 16307 12904 GO:00160…. query_1 TRUE 0.0356804 24 9028 20 0.0022153 0.8333333 GO:0051642 GO:BP centrosome localization 16307 14726 GO:0061842 query_1 TRUE 0.0356804 24 9028 20 0.0022153 0.8333333 GO:0010332 GO:BP response to gamma radiation 16307 4165 GO:0010212 query_1 TRUE 0.0356804 24 9028 20 0.0022153 0.8333333 GO:1903902 GO:BP positive regulation of viral life cycle 16307 24632 GO:00190…. query_1 TRUE 0.0356804 24 9028 20 0.0022153 0.8333333 GO:0061842 GO:BP microtubule organizing center localization 16307 16711 GO:00099…. query_1 TRUE 0.0358536 48 9028 36 0.0039876 0.7500000 GO:1902808 GO:BP positive regulation of cell cycle G1/S phase transition 16307 23702 GO:00448…. query_1 TRUE 0.0361773 81 9028 57 0.0063137 0.7037037 GO:0034101 GO:BP erythrocyte homeostasis 16307 8895 GO:0002262 query_1 TRUE 0.0362432 693 9028 418 0.0463004 0.6031746 GO:1901698 GO:BP response to nitrogen compound 16307 22778 GO:0042221 query_1 TRUE 0.0373635 45 9028 34 0.0037661 0.7555556 GO:0090311 GO:BP regulation of protein deacetylation 16307 19349 GO:00064…. query_1 TRUE 0.0373635 45 9028 34 0.0037661 0.7555556 GO:0050732 GO:BP negative regulation of peptidyl-tyrosine phosphorylation 16307 14058 GO:00019…. query_1 TRUE 0.0384537 27 9028 22 0.0024369 0.8148148 GO:0032367 GO:BP intracellular cholesterol transport 16307 7982 GO:00303…. query_1 TRUE 0.0391507 78 9028 55 0.0060922 0.7051282 GO:0030218 GO:BP erythrocyte differentiation 16307 7125 GO:00300…. query_1 TRUE 0.0392545 86 9028 60 0.0066460 0.6976744 GO:0002753 GO:BP cytosolic pattern recognition receptor signaling pathway 16307 1290 GO:00022…. query_1 TRUE 0.0395249 30 9028 24 0.0026584 0.8000000 GO:0007035 GO:BP vacuolar acidification 16307 2715 GO:0051452 query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:2000641 GO:BP regulation of early endosome to late endosome transport 16307 27359 GO:00450…. query_1 TRUE 0.0395249 30 9028 24 0.0026584 0.8000000 GO:0008214 GO:BP protein dealkylation 16307 3229 GO:0036211 query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:1900034 GO:BP regulation of cellular response to heat 16307 21357 GO:00346…. query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0046426 GO:BP negative regulation of receptor signaling pathway via JAK-STAT 16307 12922 GO:00072…. query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0042407 GO:BP cristae formation 16307 10780 GO:0007007 query_1 TRUE 0.0395249 30 9028 24 0.0026584 0.8000000 GO:0006482 GO:BP protein demethylation 16307 2283 GO:00082…. query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0045945 GO:BP positive regulation of transcription by RNA polymerase III 16307 12514 GO:00063…. query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0016137 GO:BP glycoside metabolic process 16307 5312 GO:1901657 query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0033962 GO:BP P-body assembly 16307 8853 GO:0140694 query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0031065 GO:BP positive regulation of histone deacetylation 16307 7438 GO:00165…. query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0097202 GO:BP activation of cysteine-type endopeptidase activity 16307 19711 GO:00316…. query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0071816 GO:BP tail-anchored membrane protein insertion into ER membrane 16307 18011 GO:0045048 query_1 TRUE 0.0395249 39 9028 30 0.0033230 0.7692308 GO:0060964 GO:BP regulation of miRNA-mediated gene silencing 16307 16060 GO:00351…. query_1 TRUE 0.0395249 30 9028 24 0.0026584 0.8000000 GO:0031365 GO:BP N-terminal protein amino acid modification 16307 7577 GO:0036211 query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0045292 GO:BP mRNA cis splicing, via spliceosome 16307 12115 GO:0000398 query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0009219 GO:BP pyrimidine deoxyribonucleotide metabolic process 16307 3477 GO:00062…. query_1 TRUE 0.0395249 17 9028 15 0.0016615 0.8823529 GO:0080182 GO:BP histone H3-K4 trimethylation 16307 18981 GO:00180…. query_1 TRUE 0.0399271 36 9028 28 0.0031015 0.7777778 GO:1902108 GO:BP regulation of mitochondrial membrane permeability involved in apoptotic process 16307 23162 GO:00086…. query_1 TRUE 0.0399271 36 9028 28 0.0031015 0.7777778 GO:0045023 GO:BP G0 to G1 transition 16307 11998 GO:0022402 query_1 TRUE 0.0399271 36 9028 28 0.0031015 0.7777778 GO:1902041 GO:BP regulation of extrinsic apoptotic signaling pathway via death domain receptors 16307 23103 GO:00086…. query_1 TRUE 0.0400056 33 9028 26 0.0028799 0.7878788 GO:1902110 GO:BP positive regulation of mitochondrial membrane permeability involved in apoptotic process 16307 23164 GO:19021…. query_1 TRUE 0.0400056 33 9028 26 0.0028799 0.7878788 GO:0033120 GO:BP positive regulation of RNA splicing 16307 8514 GO:00083…. query_1 TRUE 0.0404288 67 9028 48 0.0053168 0.7164179 GO:0051123 GO:BP RNA polymerase II preinitiation complex assembly 16307 14352 GO:00063…. query_1 TRUE 0.0412249 355 9028 221 0.0244794 0.6225352 GO:0016049 GO:BP cell growth 16307 5237 GO:00099…. query_1 TRUE 0.0416623 75 9028 53 0.0058706 0.7066667 GO:0043648 GO:BP dicarboxylic acid metabolic process 16307 11490 GO:0019752 query_1 TRUE 0.0416623 75 9028 53 0.0058706 0.7066667 GO:0051492 GO:BP regulation of stress fiber assembly 16307 14610 GO:00322…. query_1 TRUE 0.0417411 168 9028 110 0.0121843 0.6547619 GO:0031334 GO:BP positive regulation of protein-containing complex assembly 16307 7559 GO:00432…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0101024 GO:BP mitotic nuclear membrane organization 16307 20398 GO:00717…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0070922 GO:BP RISC complex assembly 16307 17434 GO:00226…. query_1 TRUE 0.0425971 53 9028 39 0.0043199 0.7358491 GO:0042987 GO:BP amyloid precursor protein catabolic process 16307 11109 GO:0042982 query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:1904668 GO:BP positive regulation of ubiquitin protein ligase activity 16307 25307 GO:00514…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0090522 GO:BP vesicle tethering involved in exocytosis 16307 19501 GO:00990…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0016237 GO:BP lysosomal microautophagy 16307 5337 GO:0006914 query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0019184 GO:BP nonribosomal peptide biosynthetic process 16307 5928 GO:0043043 query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0009113 GO:BP purine nucleobase biosynthetic process 16307 3374 GO:00061…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0072697 GO:BP protein localization to cell cortex 16307 18615 GO:1990778 query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0061418 GO:BP regulation of transcription from RNA polymerase II promoter in response to hypoxia 16307 16476 GO:00436…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0000467 GO:BP exonucleolytic trimming to generate mature 3’-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 16307 169 GO:00004…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0031848 GO:BP protection from non-homologous end joining at telomere 16307 7719 GO:00162…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0000459 GO:BP exonucleolytic trimming involved in rRNA processing 16307 161 GO:00004…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0051292 GO:BP nuclear pore complex assembly 16307 14476 GO:00069…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:1990481 GO:BP mRNA pseudouridine synthesis 16307 26570 GO:00015…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:1990700 GO:BP nucleolar chromatin organization 16307 26656 GO:00063…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:1902915 GO:BP negative regulation of protein polyubiquitination 16307 23792 GO:00002…. query_1 TRUE 0.0425971 9 9028 9 0.0009969 1.0000000 GO:0007084 GO:BP mitotic nuclear membrane reassembly 16307 2749 GO:00314…. query_1 TRUE 0.0426309 267 9028 169 0.0187195 0.6329588 GO:0090130 GO:BP tissue migration 16307 19187 GO:0032501 query_1 TRUE 0.0428854 64 9028 46 0.0050953 0.7187500 GO:0010906 GO:BP regulation of glucose metabolic process 16307 4629 GO:00060…. query_1 TRUE 0.0437087 150 9028 99 0.0109659 0.6600000 GO:0016051 GO:BP carbohydrate biosynthetic process 16307 5239 GO:00059…. query_1 TRUE 0.0439564 1618 9028 945 0.1046743 0.5840544 GO:0032879 GO:BP regulation of localization 16307 8344 GO:00507…. query_1 TRUE 0.0444673 88 9028 61 0.0067568 0.6931818 GO:1903076 GO:BP regulation of protein localization to plasma membrane 16307 23944 GO:00726…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:1900264 GO:BP positive regulation of DNA-directed DNA polymerase activity 16307 21563 GO:00513…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0015693 GO:BP magnesium ion transport 16307 4964 GO:0030001 query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0006264 GO:BP mitochondrial DNA replication 16307 2137 GO:00062…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:1900262 GO:BP regulation of DNA-directed DNA polymerase activity 16307 21561 GO:00513…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0007008 GO:BP outer mitochondrial membrane organization 16307 2695 GO:0007006 query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0000244 GO:BP spliceosomal tri-snRNP complex assembly 16307 72 GO:0000387 query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0009218 GO:BP pyrimidine ribonucleotide metabolic process 16307 3476 GO:00062…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:2000479 GO:BP regulation of cAMP-dependent protein kinase activity 16307 27221 GO:0071900 query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0045040 GO:BP protein insertion into mitochondrial outer membrane 16307 12006 GO:00066…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0030174 GO:BP regulation of DNA-templated DNA replication initiation 16307 7095 GO:00062…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0110156 GO:BP methylguanosine-cap decapping 16307 20662 GO:0110154 query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0007175 GO:BP negative regulation of epidermal growth factor-activated receptor activity 16307 2817 GO:00071…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0070932 GO:BP histone H3 deacetylation 16307 17441 GO:0016575 query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0098789 GO:BP pre-mRNA cleavage required for polyadenylation 16307 20085 GO:00311…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0046761 GO:BP viral budding from plasma membrane 16307 13145 GO:00467…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0009048 GO:BP dosage compensation by inactivation of X chromosome 16307 3320 GO:0007549 query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0006287 GO:BP base-excision repair, gap-filling 16307 2158 GO:00062…. query_1 TRUE 0.0451837 13 9028 12 0.0013292 0.9230769 GO:0006465 GO:BP signal peptide processing 16307 2270 GO:00065…. query_1 TRUE 0.0460157 20 9028 17 0.0018830 0.8500000 GO:0036260 GO:BP RNA capping 16307 10097 GO:0006396 query_1 TRUE 0.0460157 20 9028 17 0.0018830 0.8500000 GO:0034405 GO:BP response to fluid shear stress 16307 9117 GO:0006950 query_1 TRUE 0.0460157 20 9028 17 0.0018830 0.8500000 GO:0044827 GO:BP modulation by host of viral genome replication 16307 11939 GO:00190…. query_1 TRUE 0.0460157 20 9028 17 0.0018830 0.8500000 GO:1990182 GO:BP exosomal secretion 16307 26490 GO:00068…. query_1 TRUE 0.0460157 20 9028 17 0.0018830 0.8500000 GO:0072528 GO:BP pyrimidine-containing compound biosynthetic process 16307 18535 GO:00181…. query_1 TRUE 0.0460157 20 9028 17 0.0018830 0.8500000 GO:0009264 GO:BP deoxyribonucleotide catabolic process 16307 3521 GO:00091…. query_1 TRUE 0.0460157 20 9028 17 0.0018830 0.8500000 GO:0031440 GO:BP regulation of mRNA 3’-end processing 16307 7605 GO:00311…. query_1 TRUE 0.0470922 106 9028 72 0.0079752 0.6792453 GO:0043401 GO:BP steroid hormone mediated signaling pathway 16307 11317 GO:00097…. query_1 TRUE 0.0479831 77 9028 54 0.0059814 0.7012987 GO:0009135 GO:BP purine nucleoside diphosphate metabolic process 16307 3394 GO:0009132 query_1 TRUE 0.0486445 58 9028 42 0.0046522 0.7241379 GO:1903051 GO:BP negative regulation of proteolysis involved in protein catabolic process 16307 23920 GO:00458…. query_1 TRUE 0.0488479 44 9028 33 0.0036553 0.7500000 GO:0051058 GO:BP negative regulation of small GTPase mediated signal transduction 16307 14311 GO:00072…. query_1 TRUE 0.0488479 44 9028 33 0.0036553 0.7500000 GO:1900076 GO:BP regulation of cellular response to insulin stimulus 16307 21390 GO:00328…. query_1 TRUE 0.0488479 44 9028 33 0.0036553 0.7500000 GO:0072523 GO:BP purine-containing compound catabolic process 16307 18530 GO:00194…. query_1 TRUE 0.0499361 411 9028 253 0.0280239 0.6155718 GO:0032870 GO:BP cellular response to hormone stimulus 16307 8335 GO:00097…. query_1 TRUE 0.0000000 661 6279 599 0.0953974 0.9062027 REAC:R-HSA-8953854 REAC Metabolism of RNA 10777 1343 REAC:0000000 query_1 TRUE 0.0000000 359 6279 323 0.0514413 0.8997214 REAC:R-HSA-3700989 REAC Transcriptional Regulation by TP53 10777 2413 REAC:R-H…. query_1 TRUE 0.0000000 679 6279 547 0.0871158 0.8055965 REAC:R-HSA-1640170 REAC Cell Cycle 10777 308 REAC:0000000 query_1 TRUE 0.0000000 778 6279 613 0.0976270 0.7879177 REAC:R-HSA-2262752 REAC Cellular responses to stress 10777 326 REAC:R-H…. query_1 TRUE 0.0000000 792 6279 622 0.0990604 0.7853535 REAC:R-HSA-8953897 REAC Cellular responses to stimuli 10777 325 REAC:0000000 query_1 TRUE 0.0000000 292 6279 263 0.0418857 0.9006849 REAC:R-HSA-72766 REAC Translation 10777 2429 REAC:R-H…. query_1 TRUE 0.0000000 1945 6279 1369 0.2180283 0.7038560 REAC:R-HSA-392499 REAC Metabolism of proteins 10777 1359 REAC:0000000 query_1 TRUE 0.0000000 237 6279 220 0.0350374 0.9282700 REAC:R-HSA-72203 REAC Processing of Capped Intron-Containing Pre-mRNA 10777 1706 REAC:R-H…. query_1 TRUE 0.0000000 549 6279 447 0.0711897 0.8142077 REAC:R-HSA-69278 REAC Cell Cycle, Mitotic 10777 310 REAC:R-H…. query_1 TRUE 0.0000000 1476 6279 1061 0.1689760 0.7188347 REAC:R-HSA-74160 REAC Gene expression (Transcription) 10777 989 REAC:0000000 query_1 TRUE 0.0000000 624 6279 493 0.0785157 0.7900641 REAC:R-HSA-199991 REAC Membrane Trafficking 10777 1338 REAC:R-H…. query_1 TRUE 0.0000000 178 6279 169 0.0269151 0.9494382 REAC:R-HSA-72163 REAC mRNA Splicing - Major Pathway 10777 2566 REAC:R-H…. query_1 TRUE 0.0000000 162 6279 156 0.0248447 0.9629630 REAC:R-HSA-69242 REAC S Phase 10777 1989 REAC:R-H…. query_1 TRUE 0.0000000 186 6279 175 0.0278707 0.9408602 REAC:R-HSA-72172 REAC mRNA Splicing 10777 2565 REAC:R-H…. query_1 TRUE 0.0000000 229 6279 205 0.0326485 0.8951965 REAC:R-HSA-2555396 REAC Mitotic Metaphase and Anaphase 10777 1402 REAC:R-H…. query_1 TRUE 0.0000000 228 6279 204 0.0324892 0.8947368 REAC:R-HSA-68882 REAC Mitotic Anaphase 10777 1399 REAC:R-H…. query_1 TRUE 0.0000000 224 6279 199 0.0316929 0.8883929 REAC:R-HSA-162906 REAC HIV Infection 10777 1044 REAC:R-H…. query_1 TRUE 0.0000000 147 6279 139 0.0221373 0.9455782 REAC:R-HSA-453279 REAC Mitotic G1 phase and G1/S transition 10777 1400 REAC:R-H…. query_1 TRUE 0.0000000 1415 6279 995 0.1584647 0.7031802 REAC:R-HSA-597592 REAC Post-translational protein modification 10777 1686 REAC:R-H…. query_1 TRUE 0.0000000 1340 6279 947 0.1508202 0.7067164 REAC:R-HSA-73857 REAC RNA Polymerase II Transcription 10777 1798 REAC:R-H…. query_1 TRUE 0.0000000 192 6279 174 0.0277114 0.9062500 REAC:R-HSA-8868773 REAC rRNA processing in the nucleus and cytosol 10777 2593 REAC:R-H…. query_1 TRUE 0.0000000 130 6279 125 0.0199076 0.9615385 REAC:R-HSA-69206 REAC G1/S Transition 10777 948 REAC:R-H…. query_1 TRUE 0.0000000 202 6279 181 0.0288262 0.8960396 REAC:R-HSA-72312 REAC rRNA processing 10777 2591 REAC:R-H…. query_1 TRUE 0.0000000 449 6279 356 0.0566969 0.7928731 REAC:R-HSA-9012999 REAC RHO GTPase cycle 10777 1755 REAC:R-H…. query_1 TRUE 0.0000000 308 6279 257 0.0409301 0.8344156 REAC:R-HSA-983168 REAC Antigen processing: Ubiquitination & Proteasome degradation 10777 148 REAC:R-H…. query_1 TRUE 0.0000000 182 6279 164 0.0261188 0.9010989 REAC:R-HSA-6791226 REAC Major pathway of rRNA processing in the nucleolus and cytosol 10777 1319 REAC:R-H…. query_1 TRUE 0.0000000 121 6279 116 0.0184743 0.9586777 REAC:R-HSA-69239 REAC Synthesis of DNA 10777 2245 REAC:R-H…. query_1 TRUE 0.0000000 2072 6279 1395 0.2221691 0.6732625 REAC:R-HSA-1430728 REAC Metabolism 10777 1341 REAC:0000000 query_1 TRUE 0.0000000 152 6279 140 0.0222965 0.9210526 REAC:R-HSA-168255 REAC Influenza Infection 10777 1125 REAC:R-H…. query_1 TRUE 0.0000000 380 6279 306 0.0487339 0.8052632 REAC:R-HSA-983169 REAC Class I MHC mediated antigen processing & presentation 10777 353 REAC:R-H…. query_1 TRUE 0.0000000 717 6279 532 0.0847269 0.7419805 REAC:R-HSA-9716542 REAC Signaling by Rho GTPases, Miro GTPases and RHOBTB3 10777 2180 REAC:R-H…. query_1 TRUE 0.0000000 417 6279 330 0.0525561 0.7913669 REAC:R-HSA-5663202 REAC Diseases of signal transduction by growth factor receptors and second messengers 10777 735 REAC:R-H…. query_1 TRUE 0.0000000 133 6279 124 0.0197484 0.9323308 REAC:R-HSA-168273 REAC Influenza Viral RNA Transcription and Replication 10777 1126 REAC:R-H…. query_1 TRUE 0.0000000 200 6279 175 0.0278707 0.8750000 REAC:R-HSA-68877 REAC Mitotic Prometaphase 10777 1404 REAC:R-H…. query_1 TRUE 0.0000000 188 6279 166 0.0264373 0.8829787 REAC:R-HSA-2467813 REAC Separation of Sister Chromatids 10777 2081 REAC:R-H…. query_1 TRUE 0.0000000 289 6279 239 0.0380634 0.8269896 REAC:R-HSA-69620 REAC Cell Cycle Checkpoints 10777 309 REAC:R-H…. query_1 TRUE 0.0000000 109 6279 104 0.0165631 0.9541284 REAC:R-HSA-5696398 REAC Nucleotide Excision Repair 10777 1536 REAC:R-H…. query_1 TRUE 0.0000000 138 6279 127 0.0202262 0.9202899 REAC:R-HSA-6807070 REAC PTEN Regulation 10777 1614 REAC:R-H…. query_1 TRUE 0.0000000 702 6279 518 0.0824972 0.7378917 REAC:R-HSA-194315 REAC Signaling by Rho GTPases 10777 2179 REAC:R-H…. query_1 TRUE 0.0000000 198 6279 172 0.0273929 0.8686869 REAC:R-HSA-453274 REAC Mitotic G2-G2/M phases 10777 1401 REAC:R-H…. query_1 TRUE 0.0000000 116 6279 109 0.0173595 0.9396552 REAC:R-HSA-927802 REAC Nonsense-Mediated Decay (NMD) 10777 1522 REAC:R-H…. query_1 TRUE 0.0000000 196 6279 170 0.0270744 0.8673469 REAC:R-HSA-69275 REAC G2/M Transition 10777 954 REAC:R-H…. query_1 TRUE 0.0000000 116 6279 109 0.0173595 0.9396552 REAC:R-HSA-975957 REAC Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 10777 1520 REAC:R-H…. query_1 TRUE 0.0000000 145 6279 131 0.0208632 0.9034483 REAC:R-HSA-162587 REAC HIV Life Cycle 10777 1045 REAC:R-H…. query_1 TRUE 0.0000000 132 6279 121 0.0192706 0.9166667 REAC:R-HSA-162599 REAC Late Phase of HIV Life Cycle 10777 1242 REAC:R-H…. query_1 TRUE 0.0000000 330 6279 264 0.0420449 0.8000000 REAC:R-HSA-73894 REAC DNA Repair 10777 423 REAC:0000000 query_1 TRUE 0.0000000 120 6279 111 0.0176780 0.9250000 REAC:R-HSA-72737 REAC Cap-dependent Translation Initiation 10777 293 REAC:R-H…. query_1 TRUE 0.0000000 120 6279 111 0.0176780 0.9250000 REAC:R-HSA-72613 REAC Eukaryotic Translation Initiation 10777 828 REAC:R-H…. query_1 TRUE 0.0000000 408 6279 317 0.0504857 0.7769608 REAC:R-HSA-68886 REAC M Phase 10777 1278 REAC:R-H…. query_1 TRUE 0.0000000 354 6279 280 0.0445931 0.7909605 REAC:R-HSA-9679506 REAC SARS-CoV Infections 10777 1990 REAC:R-H…. query_1 TRUE 0.0000000 239 6279 199 0.0316929 0.8326360 REAC:R-HSA-8951664 REAC Neddylation 10777 1474 REAC:R-H…. query_1 TRUE 0.0000000 157 6279 139 0.0221373 0.8853503 REAC:R-HSA-9711097 REAC Cellular response to starvation 10777 324 REAC:R-H…. query_1 TRUE 0.0000000 109 6279 102 0.0162446 0.9357798 REAC:R-HSA-69618 REAC Mitotic Spindle Checkpoint 10777 1406 REAC:R-H…. query_1 TRUE 0.0000000 160 6279 141 0.0224558 0.8812500 REAC:R-HSA-5633007 REAC Regulation of TP53 Activity 10777 1901 REAC:R-H…. query_1 TRUE 0.0000000 113 6279 105 0.0167224 0.9292035 REAC:R-HSA-1799339 REAC SRP-dependent cotranslational protein targeting to membrane 10777 2034 REAC:R-H…. query_1 TRUE 0.0000000 93 6279 89 0.0141742 0.9569892 REAC:R-HSA-5368287 REAC Mitochondrial translation 10777 1394 REAC:R-H…. query_1 TRUE 0.0000000 171 6279 149 0.0237299 0.8713450 REAC:R-HSA-9010553 REAC Regulation of expression of SLITs and ROBOs 10777 1916 REAC:R-H…. query_1 TRUE 0.0000000 205 6279 173 0.0275522 0.8439024 REAC:R-HSA-5357801 REAC Programmed Cell Death 10777 1713 REAC:0000000 query_1 TRUE 0.0000000 84 6279 81 0.0129001 0.9642857 REAC:R-HSA-5696399 REAC Global Genome Nucleotide Excision Repair (GG-NER) 10777 993 REAC:R-H…. query_1 TRUE 0.0000000 84 6279 81 0.0129001 0.9642857 REAC:R-HSA-69656 REAC Cyclin A:Cdk2-associated events at S phase entry 10777 398 REAC:R-H…. query_1 TRUE 0.0000000 113 6279 104 0.0165631 0.9203540 REAC:R-HSA-72706 REAC GTP hydrolysis and joining of the 60S ribosomal subunit 10777 973 REAC:R-H…. query_1 TRUE 0.0000000 112 6279 103 0.0164039 0.9196429 REAC:R-HSA-156827 REAC L13a-mediated translational silencing of Ceruloplasmin expression 10777 1231 REAC:R-H…. query_1 TRUE 0.0000000 191 6279 162 0.0258003 0.8481675 REAC:R-HSA-9711123 REAC Cellular response to chemical stress 10777 321 REAC:R-H…. query_1 TRUE 0.0000000 82 6279 79 0.0125816 0.9634146 REAC:R-HSA-69202 REAC Cyclin E associated events during G1/S transition 10777 400 REAC:R-H…. query_1 TRUE 0.0000000 87 6279 83 0.0132187 0.9540230 REAC:R-HSA-5419276 REAC Mitochondrial translation termination 10777 1397 REAC:R-H…. query_1 TRUE 0.0000000 87 6279 83 0.0132187 0.9540230 REAC:R-HSA-5368286 REAC Mitochondrial translation initiation 10777 1396 REAC:R-H…. query_1 TRUE 0.0000000 87 6279 83 0.0132187 0.9540230 REAC:R-HSA-5389840 REAC Mitochondrial translation elongation 10777 1395 REAC:R-H…. query_1 TRUE 0.0000000 92 6279 87 0.0138557 0.9456522 REAC:R-HSA-69052 REAC Switching of origins to a post-replicative state 10777 2234 REAC:R-H…. query_1 TRUE 0.0000000 279 6279 224 0.0356745 0.8028674 REAC:R-HSA-9694516 REAC SARS-CoV-2 Infection 10777 2000 REAC:R-H…. query_1 TRUE 0.0000000 1219 6279 835 0.1329830 0.6849877 REAC:R-HSA-212436 REAC Generic Transcription Pathway 10777 991 REAC:R-H…. query_1 TRUE 0.0000000 217 6279 179 0.0285077 0.8248848 REAC:R-HSA-376176 REAC Signaling by ROBO receptors 10777 2176 REAC:R-H…. query_1 TRUE 0.0000000 78 6279 75 0.0119446 0.9615385 REAC:R-HSA-1169410 REAC Antiviral mechanism by IFN-stimulated genes 10777 151 REAC:R-H…. query_1 TRUE 0.0000000 102 6279 94 0.0149705 0.9215686 REAC:R-HSA-9633012 REAC Response of EIF2AK4 (GCN2) to amino acid deficiency 10777 1966 REAC:R-H…. query_1 TRUE 0.0000000 102 6279 94 0.0149705 0.9215686 REAC:R-HSA-72689 REAC Formation of a pool of free 40S subunits 10777 906 REAC:R-H…. query_1 TRUE 0.0000000 176 6279 149 0.0237299 0.8465909 REAC:R-HSA-109581 REAC Apoptosis 10777 152 REAC:R-H…. query_1 TRUE 0.0000000 96 6279 89 0.0141742 0.9270833 REAC:R-HSA-975956 REAC Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 10777 1521 REAC:R-H…. query_1 TRUE 0.0000000 305 6279 239 0.0380634 0.7836066 REAC:R-HSA-446203 REAC Asparagine N-linked glycosylation 10777 163 REAC:R-H…. query_1 TRUE 0.0000000 94 6279 87 0.0138557 0.9255319 REAC:R-HSA-72764 REAC Eukaryotic Translation Termination 10777 829 REAC:R-H…. query_1 TRUE 0.0000000 94 6279 87 0.0138557 0.9255319 REAC:R-HSA-156842 REAC Eukaryotic Translation Elongation 10777 827 REAC:R-H…. query_1 TRUE 0.0000000 101 6279 92 0.0146520 0.9108911 REAC:R-HSA-9755511 REAC KEAP1-NFE2L2 pathway 10777 1220 REAC:R-H…. query_1 TRUE 0.0000000 92 6279 85 0.0135372 0.9239130 REAC:R-HSA-141424 REAC Amplification of signal from the kinetochores 10777 138 REAC:R-H…. query_1 TRUE 0.0000000 92 6279 85 0.0135372 0.9239130 REAC:R-HSA-141444 REAC Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 10777 137 REAC:R-H…. query_1 TRUE 0.0000000 125 6279 110 0.0175187 0.8800000 REAC:R-HSA-162909 REAC Host Interactions of HIV factors 10777 1073 REAC:R-H…. query_1 TRUE 0.0000000 77 6279 73 0.0116261 0.9480519 REAC:R-HSA-6781827 REAC Transcription-Coupled Nucleotide Excision Repair (TC-NER) 10777 2408 REAC:R-H…. query_1 TRUE 0.0000000 86 6279 80 0.0127409 0.9302326 REAC:R-HSA-2565942 REAC Regulation of PLK1 Activity at G2/M Transition 10777 1890 REAC:R-H…. query_1 TRUE 0.0000000 86 6279 80 0.0127409 0.9302326 REAC:R-HSA-450531 REAC Regulation of mRNA stability by proteins that bind AU-rich elements 10777 1928 REAC:R-H…. query_1 TRUE 0.0000000 90 6279 83 0.0132187 0.9222222 REAC:R-HSA-156902 REAC Peptide chain elongation 10777 1633 REAC:R-H…. query_1 TRUE 0.0000000 90 6279 83 0.0132187 0.9222222 REAC:R-HSA-192823 REAC Viral mRNA Translation 10777 2511 REAC:R-H…. query_1 TRUE 0.0000000 294 6279 229 0.0364708 0.7789116 REAC:R-HSA-1852241 REAC Organelle biogenesis and maintenance 10777 1558 REAC:0000000 query_1 TRUE 0.0000000 103 6279 93 0.0148113 0.9029126 REAC:R-HSA-72306 REAC tRNA processing 10777 2602 REAC:R-H…. query_1 TRUE 0.0000000 94 6279 86 0.0136964 0.9148936 REAC:R-HSA-2408557 REAC Selenocysteine synthesis 10777 2065 REAC:R-H…. query_1 TRUE 0.0000000 70 6279 67 0.0106705 0.9571429 REAC:R-HSA-1169408 REAC ISG15 antiviral mechanism 10777 1106 REAC:R-H…. query_1 TRUE 0.0000000 64 6279 62 0.0098742 0.9687500 REAC:R-HSA-174084 REAC Autodegradation of Cdh1 by Cdh1:APC/C 10777 183 REAC:R-H…. query_1 TRUE 0.0000000 97 6279 88 0.0140150 0.9072165 REAC:R-HSA-5620912 REAC Anchoring of the basal body to the plasma membrane 10777 141 REAC:R-H…. query_1 TRUE 0.0000000 74 6279 70 0.0111483 0.9459459 REAC:R-HSA-174178 REAC APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 10777 25 REAC:R-H…. query_1 TRUE 0.0000000 88 6279 81 0.0129001 0.9204545 REAC:R-HSA-174143 REAC APC/C-mediated degradation of cell cycle proteins 10777 21 REAC:R-H…. query_1 TRUE 0.0000000 88 6279 81 0.0129001 0.9204545 REAC:R-HSA-453276 REAC Regulation of mitotic cell cycle 10777 1929 REAC:R-H…. query_1 TRUE 0.0000000 92 6279 84 0.0133779 0.9130435 REAC:R-HSA-168164 REAC Toll Like Receptor 3 (TLR3) Cascade 10777 2382 REAC:R-H…. query_1 TRUE 0.0000000 92 6279 84 0.0133779 0.9130435 REAC:R-HSA-6804756 REAC Regulation of TP53 Activity through Phosphorylation 10777 1905 REAC:R-H…. query_1 TRUE 0.0000000 252 6279 199 0.0316929 0.7896825 REAC:R-HSA-1257604 REAC PIP3 activates AKT signaling 10777 1591 REAC:R-H…. query_1 TRUE 0.0000000 96 6279 87 0.0138557 0.9062500 REAC:R-HSA-937061 REAC TRIF(TICAM1)-mediated TLR4 signaling 10777 2336 REAC:R-H…. query_1 TRUE 0.0000000 96 6279 87 0.0138557 0.9062500 REAC:R-HSA-166166 REAC MyD88-independent TLR4 cascade 10777 1420 REAC:R-H…. query_1 TRUE 0.0000000 78 6279 73 0.0116261 0.9358974 REAC:R-HSA-9759194 REAC Nuclear events mediated by NFE2L2 10777 1531 REAC:R-H…. query_1 TRUE 0.0000000 73 6279 69 0.0109890 0.9452055 REAC:R-HSA-6807505 REAC RNA polymerase II transcribes snRNA genes 10777 1812 REAC:R-H…. query_1 TRUE 0.0000000 202 6279 164 0.0261188 0.8118812 REAC:R-HSA-5617833 REAC Cilium Assembly 10777 346 REAC:R-H…. query_1 TRUE 0.0000000 202 6279 164 0.0261188 0.8118812 REAC:R-HSA-6811442 REAC Intra-Golgi and retrograde Golgi-to-ER traffic 10777 1202 REAC:R-H…. query_1 TRUE 0.0000000 149 6279 126 0.0200669 0.8456376 REAC:R-HSA-9612973 REAC Autophagy 10777 186 REAC:0000000 query_1 TRUE 0.0000000 718 6279 505 0.0804268 0.7033426 REAC:R-HSA-5653656 REAC Vesicle-mediated transport 10777 2507 REAC:0000000 query_1 TRUE 0.0000000 81 6279 75 0.0119446 0.9259259 REAC:R-HSA-176408 REAC Regulation of APC/C activators between G1/S and early anaphase 10777 1870 REAC:R-H…. query_1 TRUE 0.0000000 94 6279 85 0.0135372 0.9042553 REAC:R-HSA-8878159 REAC Transcriptional regulation by RUNX3 10777 2420 REAC:R-H…. query_1 TRUE 0.0000000 176 6279 145 0.0230928 0.8238636 REAC:R-HSA-2990846 REAC SUMOylation 10777 2044 REAC:R-H…. query_1 TRUE 0.0000000 170 6279 140 0.0222965 0.8235294 REAC:R-HSA-3108232 REAC SUMO E3 ligases SUMOylate target proteins 10777 2040 REAC:R-H…. query_1 TRUE 0.0000000 53 6279 52 0.0082816 0.9811321 REAC:R-HSA-1655829 REAC Regulation of cholesterol biosynthesis by SREBP (SREBF) 10777 1912 REAC:R-H…. query_1 TRUE 0.0000000 134 6279 114 0.0181558 0.8507463 REAC:R-HSA-1632852 REAC Macroautophagy 10777 1318 REAC:R-H…. query_1 TRUE 0.0000000 87 6279 79 0.0125816 0.9080460 REAC:R-HSA-170834 REAC Signaling by TGF-beta Receptor Complex 10777 2183 REAC:R-H…. query_1 TRUE 0.0000000 91 6279 82 0.0130594 0.9010989 REAC:R-HSA-381119 REAC Unfolded Protein Response (UPR) 10777 2486 REAC:R-H…. query_1 TRUE 0.0000000 73 6279 68 0.0108297 0.9315068 REAC:R-HSA-69017 REAC CDK-mediated phosphorylation and removal of Cdc6 10777 260 REAC:R-H…. query_1 TRUE 0.0000000 63 6279 60 0.0095557 0.9523810 REAC:R-HSA-6782210 REAC Gap-filling DNA repair synthesis and ligation in TC-NER 10777 984 REAC:R-H…. query_1 TRUE 0.0000000 68 6279 64 0.0101927 0.9411765 REAC:R-HSA-174154 REAC APC/C:Cdc20 mediated degradation of Securin 10777 23 REAC:R-H…. query_1 TRUE 0.0000000 77 6279 71 0.0113075 0.9220779 REAC:R-HSA-176814 REAC Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 10777 70 REAC:R-H…. query_1 TRUE 0.0000000 72 6279 67 0.0106705 0.9305556 REAC:R-HSA-3108214 REAC SUMOylation of DNA damage response and repair proteins 10777 2045 REAC:R-H…. query_1 TRUE 0.0000000 76 6279 70 0.0111483 0.9210526 REAC:R-HSA-176409 REAC APC/C:Cdc20 mediated degradation of mitotic proteins 10777 24 REAC:R-H…. query_1 TRUE 0.0000000 97 6279 86 0.0136964 0.8865979 REAC:R-HSA-5607764 REAC CLEC7A (Dectin-1) signaling 10777 263 REAC:R-H…. query_1 TRUE 0.0000000 1823 6279 1186 0.1888836 0.6505760 REAC:R-HSA-1643685 REAC Disease 10777 710 REAC:0000000 query_1 TRUE 0.0000000 80 6279 73 0.0116261 0.9125000 REAC:R-HSA-72202 REAC Transport of Mature Transcript to Cytoplasm 10777 2447 REAC:R-H…. query_1 TRUE 0.0000000 71 6279 66 0.0105112 0.9295775 REAC:R-HSA-68949 REAC Orc1 removal from chromatin 10777 1556 REAC:R-H…. query_1 TRUE 0.0000000 123 6279 105 0.0167224 0.8536585 REAC:R-HSA-2500257 REAC Resolution of Sister Chromatid Cohesion 10777 1962 REAC:R-H…. query_1 TRUE 0.0000000 158 6279 130 0.0207039 0.8227848 REAC:R-HSA-9609507 REAC Protein localization 10777 1722 REAC:0000000 query_1 TRUE 0.0000000 83 6279 75 0.0119446 0.9036145 REAC:R-HSA-195253 REAC Degradation of beta-catenin by the destruction complex 10777 690 REAC:R-H…. query_1 TRUE 0.0000000 60 6279 57 0.0090779 0.9500000 REAC:R-HSA-187577 REAC SCF(Skp2)-mediated degradation of p27/p21 10777 2007 REAC:R-H…. query_1 TRUE 0.0000000 136 6279 114 0.0181558 0.8382353 REAC:R-HSA-5663220 REAC RHO GTPases Activate Formins 10777 1756 REAC:R-H…. query_1 TRUE 0.0000000 74 6279 68 0.0108297 0.9189189 REAC:R-HSA-179419 REAC APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 10777 26 REAC:R-H…. query_1 TRUE 0.0000000 64 6279 60 0.0095557 0.9375000 REAC:R-HSA-6782135 REAC Dual incision in TC-NER 10777 770 REAC:R-H…. query_1 TRUE 0.0000000 73 6279 67 0.0106705 0.9178082 REAC:R-HSA-174184 REAC Cdc20:Phospho-APC/C mediated degradation of Cyclin A 10777 307 REAC:R-H…. query_1 TRUE 0.0000000 292 6279 221 0.0351967 0.7568493 REAC:R-HSA-9006925 REAC Intracellular signaling by second messengers 10777 1206 REAC:R-H…. query_1 TRUE 0.0000000 68 6279 63 0.0100334 0.9264706 REAC:R-HSA-5685942 REAC HDR through Homologous Recombination (HRR) 10777 1039 REAC:R-H…. query_1 TRUE 0.0000000 63 6279 59 0.0093964 0.9365079 REAC:R-HSA-450294 REAC MAP kinase activation 10777 1279 REAC:R-H…. query_1 TRUE 0.0000000 72 6279 66 0.0105112 0.9166667 REAC:R-HSA-8854518 REAC AURKA Activation by TPX2 10777 37 REAC:R-H…. query_1 TRUE 0.0000000 115 6279 98 0.0156076 0.8521739 REAC:R-HSA-9648025 REAC EML4 and NUDC in mitotic spindle formation 10777 779 REAC:R-H…. query_1 TRUE 0.0000000 67 6279 62 0.0098742 0.9253731 REAC:R-HSA-1169091 REAC Activation of NF-kappaB in B cells 10777 83 REAC:R-H…. query_1 TRUE 0.0000000 80 6279 72 0.0114668 0.9000000 REAC:R-HSA-674695 REAC RNA Polymerase II Pre-transcription Events 10777 1796 REAC:R-H…. query_1 TRUE 0.0000000 84 6279 75 0.0119446 0.8928571 REAC:R-HSA-5628897 REAC TP53 Regulates Metabolic Genes 10777 2317 REAC:R-H…. query_1 TRUE 0.0000000 52 6279 50 0.0079631 0.9615385 REAC:R-HSA-9762114 REAC GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 10777 972 REAC:R-H…. query_1 TRUE 0.0000000 74 6279 67 0.0106705 0.9054054 REAC:R-HSA-9013106 REAC RHOC GTPase cycle 10777 1773 REAC:R-H…. query_1 TRUE 0.0000000 120 6279 101 0.0160854 0.8416667 REAC:R-HSA-9007101 REAC Rab regulation of trafficking 10777 1846 REAC:R-H…. query_1 TRUE 0.0000000 65 6279 60 0.0095557 0.9230769 REAC:R-HSA-73856 REAC RNA Polymerase II Transcription Termination 10777 1803 REAC:R-H…. query_1 TRUE 0.0000000 101 6279 87 0.0138557 0.8613861 REAC:R-HSA-9020702 REAC Interleukin-1 signaling 10777 1173 REAC:R-H…. query_1 TRUE 0.0000000 732 6279 503 0.0801083 0.6871585 REAC:R-HSA-556833 REAC Metabolism of lipids 10777 1353 REAC:R-H…. query_1 TRUE 0.0000000 69 6279 63 0.0100334 0.9130435 REAC:R-HSA-380284 REAC Loss of proteins required for interphase microtubule organization from the centrosome 10777 1273 REAC:R-H…. query_1 TRUE 0.0000000 69 6279 63 0.0100334 0.9130435 REAC:R-HSA-8948751 REAC Regulation of PTEN stability and activity 10777 1894 REAC:R-H…. query_1 TRUE 0.0000000 60 6279 56 0.0089186 0.9333333 REAC:R-HSA-5607761 REAC Dectin-1 mediated noncanonical NF-kB signaling 10777 435 REAC:R-H…. query_1 TRUE 0.0000000 69 6279 63 0.0100334 0.9130435 REAC:R-HSA-380259 REAC Loss of Nlp from mitotic centrosomes 10777 1269 REAC:R-H…. query_1 TRUE 0.0000000 50 6279 48 0.0076445 0.9600000 REAC:R-HSA-9675135 REAC Diseases of DNA repair 10777 721 REAC:R-H…. query_1 TRUE 0.0000000 81 6279 72 0.0114668 0.8888889 REAC:R-HSA-380270 REAC Recruitment of mitotic centrosome proteins and complexes 10777 1858 REAC:R-H…. query_1 TRUE 0.0000000 81 6279 72 0.0114668 0.8888889 REAC:R-HSA-380287 REAC Centrosome maturation 10777 327 REAC:R-H…. query_1 TRUE 0.0000000 59 6279 55 0.0087594 0.9322034 REAC:R-HSA-5676590 REAC NIK–>noncanonical NF-kB signaling 10777 1443 REAC:R-H…. query_1 TRUE 0.0000000 54 6279 51 0.0081223 0.9444444 REAC:R-HSA-8941858 REAC Regulation of RUNX3 expression and activity 10777 1898 REAC:R-H…. query_1 TRUE 0.0000000 103 6279 88 0.0140150 0.8543689 REAC:R-HSA-611105 REAC Respiratory electron transport 10777 1963 REAC:R-H…. query_1 TRUE 0.0000000 71 6279 64 0.0101927 0.9014085 REAC:R-HSA-159236 REAC Transport of Mature mRNA derived from an Intron-Containing Transcript 10777 2449 REAC:R-H…. query_1 TRUE 0.0000000 48 6279 46 0.0073260 0.9583333 REAC:R-HSA-73893 REAC DNA Damage Bypass 10777 417 REAC:R-H…. query_1 TRUE 0.0000000 53 6279 50 0.0079631 0.9433962 REAC:R-HSA-9604323 REAC Negative regulation of NOTCH4 signaling 10777 1491 REAC:R-H…. query_1 TRUE 0.0000000 36 6279 36 0.0057334 1.0000000 REAC:R-HSA-76046 REAC RNA Polymerase III Transcription Initiation 10777 1807 REAC:R-H…. query_1 TRUE 0.0000001 94 6279 81 0.0129001 0.8617021 REAC:R-HSA-168138 REAC Toll Like Receptor 9 (TLR9) Cascade 10777 2386 REAC:R-H…. query_1 TRUE 0.0000001 57 6279 53 0.0084408 0.9298246 REAC:R-HSA-9694635 REAC Translation of Structural Proteins 10777 2435 REAC:R-H…. query_1 TRUE 0.0000001 57 6279 53 0.0084408 0.9298246 REAC:R-HSA-9772573 REAC Late SARS-CoV-2 Infection Events 10777 1243 REAC:R-H…. query_1 TRUE 0.0000001 52 6279 49 0.0078038 0.9423077 REAC:R-HSA-6781823 REAC Formation of TC-NER Pre-Incision Complex 10777 905 REAC:R-H…. query_1 TRUE 0.0000001 61 6279 56 0.0089186 0.9180328 REAC:R-HSA-6796648 REAC TP53 Regulates Transcription of DNA Repair Genes 10777 2321 REAC:R-H…. query_1 TRUE 0.0000001 89 6279 77 0.0122631 0.8651685 REAC:R-HSA-975138 REAC TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 10777 2333 REAC:R-H…. query_1 TRUE 0.0000001 41 6279 40 0.0063704 0.9756098 REAC:R-HSA-749476 REAC RNA Polymerase III Abortive And Retractive Initiation 10777 1804 REAC:R-H…. query_1 TRUE 0.0000001 41 6279 40 0.0063704 0.9756098 REAC:R-HSA-74158 REAC RNA Polymerase III Transcription 10777 1806 REAC:R-H…. query_1 TRUE 0.0000001 56 6279 52 0.0082816 0.9285714 REAC:R-HSA-5362768 REAC Hh mutants are degraded by ERAD 10777 1064 REAC:R-H…. query_1 TRUE 0.0000001 56 6279 52 0.0082816 0.9285714 REAC:R-HSA-72187 REAC mRNA 3’-end processing 10777 2560 REAC:R-H…. query_1 TRUE 0.0000001 56 6279 52 0.0082816 0.9285714 REAC:R-HSA-429914 REAC Deadenylation-dependent mRNA decay 10777 433 REAC:R-H…. query_1 TRUE 0.0000001 69 6279 62 0.0098742 0.8985507 REAC:R-HSA-167172 REAC Transcription of the HIV genome 10777 2407 REAC:R-H…. query_1 TRUE 0.0000001 81 6279 71 0.0113075 0.8765432 REAC:R-HSA-9013694 REAC Signaling by NOTCH4 10777 2158 REAC:R-H…. query_1 TRUE 0.0000001 114 6279 95 0.0151298 0.8333333 REAC:R-HSA-400206 REAC Regulation of lipid metabolism by PPARalpha 10777 1926 REAC:R-H…. query_1 TRUE 0.0000001 60 6279 55 0.0087594 0.9166667 REAC:R-HSA-72662 REAC Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 10777 101 REAC:R-H…. query_1 TRUE 0.0000001 84 6279 73 0.0116261 0.8690476 REAC:R-HSA-168142 REAC Toll Like Receptor 10 (TLR10) Cascade 10777 2380 REAC:R-H…. query_1 TRUE 0.0000001 84 6279 73 0.0116261 0.8690476 REAC:R-HSA-168176 REAC Toll Like Receptor 5 (TLR5) Cascade 10777 2384 REAC:R-H…. query_1 TRUE 0.0000001 84 6279 73 0.0116261 0.8690476 REAC:R-HSA-975871 REAC MyD88 cascade initiated on plasma membrane 10777 1416 REAC:R-H…. query_1 TRUE 0.0000001 113 6279 94 0.0149705 0.8318584 REAC:R-HSA-1989781 REAC PPARA activates gene expression 10777 1611 REAC:R-H…. query_1 TRUE 0.0000001 80 6279 70 0.0111483 0.8750000 REAC:R-HSA-1168372 REAC Downstream signaling events of B Cell Receptor (BCR) 10777 753 REAC:R-H…. query_1 TRUE 0.0000001 68 6279 61 0.0097149 0.8970588 REAC:R-HSA-204005 REAC COPII-mediated vesicle transport 10777 268 REAC:R-H…. query_1 TRUE 0.0000001 68 6279 61 0.0097149 0.8970588 REAC:R-HSA-69615 REAC G1/S DNA Damage Checkpoints 10777 947 REAC:R-H…. query_1 TRUE 0.0000001 55 6279 51 0.0081223 0.9272727 REAC:R-HSA-6784531 REAC tRNA processing in the nucleus 10777 2604 REAC:R-H…. query_1 TRUE 0.0000001 72 6279 64 0.0101927 0.8888889 REAC:R-HSA-199992 REAC trans-Golgi Network Vesicle Budding 10777 2608 REAC:R-H…. query_1 TRUE 0.0000001 55 6279 51 0.0081223 0.9272727 REAC:R-HSA-174113 REAC SCF-beta-TrCP mediated degradation of Emi1 10777 2008 REAC:R-H…. query_1 TRUE 0.0000001 40 6279 39 0.0062112 0.9750000 REAC:R-HSA-2426168 REAC Activation of gene expression by SREBF (SREBP) 10777 97 REAC:R-H…. query_1 TRUE 0.0000002 59 6279 54 0.0086001 0.9152542 REAC:R-HSA-72649 REAC Translation initiation complex formation 10777 2430 REAC:R-H…. query_1 TRUE 0.0000002 59 6279 54 0.0086001 0.9152542 REAC:R-HSA-8943724 REAC Regulation of PTEN gene transcription 10777 1891 REAC:R-H…. query_1 TRUE 0.0000002 59 6279 54 0.0086001 0.9152542 REAC:R-HSA-72702 REAC Ribosomal scanning and start codon recognition 10777 1984 REAC:R-H…. query_1 TRUE 0.0000002 75 6279 66 0.0105112 0.8800000 REAC:R-HSA-1234174 REAC Cellular response to hypoxia 10777 323 REAC:R-H…. query_1 TRUE 0.0000002 71 6279 63 0.0100334 0.8873239 REAC:R-HSA-448424 REAC Interleukin-17 signaling 10777 1178 REAC:R-H…. query_1 TRUE 0.0000002 155 6279 123 0.0195891 0.7935484 REAC:R-HSA-199977 REAC ER to Golgi Anterograde Transport 10777 785 REAC:R-H…. query_1 TRUE 0.0000002 54 6279 50 0.0079631 0.9259259 REAC:R-HSA-109606 REAC Intrinsic Pathway for Apoptosis 10777 1208 REAC:R-H…. query_1 TRUE 0.0000002 90 6279 77 0.0122631 0.8555556 REAC:R-HSA-975155 REAC MyD88 dependent cascade initiated on endosome 10777 1419 REAC:R-H…. query_1 TRUE 0.0000003 49 6279 46 0.0073260 0.9387755 REAC:R-HSA-6791312 REAC TP53 Regulates Transcription of Cell Cycle Genes 10777 2319 REAC:R-H…. query_1 TRUE 0.0000003 186 6279 144 0.0229336 0.7741935 REAC:R-HSA-948021 REAC Transport to the Golgi and subsequent modification 10777 2467 REAC:R-H…. query_1 TRUE 0.0000003 66 6279 59 0.0093964 0.8939394 REAC:R-HSA-69563 REAC p53-Dependent G1 DNA Damage Response 10777 2576 REAC:R-H…. query_1 TRUE 0.0000003 66 6279 59 0.0093964 0.8939394 REAC:R-HSA-69580 REAC p53-Dependent G1/S DNA damage checkpoint 10777 2577 REAC:R-H…. query_1 TRUE 0.0000003 66 6279 59 0.0093964 0.8939394 REAC:R-HSA-1234176 REAC Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 10777 1567 REAC:R-H…. query_1 TRUE 0.0000003 70 6279 62 0.0098742 0.8857143 REAC:R-HSA-9013026 REAC RHOB GTPase cycle 10777 1768 REAC:R-H…. query_1 TRUE 0.0000003 53 6279 49 0.0078038 0.9245283 REAC:R-HSA-9700206 REAC Signaling by ALK in cancer 10777 2096 REAC:R-H…. query_1 TRUE 0.0000003 53 6279 49 0.0078038 0.9245283 REAC:R-HSA-169911 REAC Regulation of Apoptosis 10777 1871 REAC:R-H…. query_1 TRUE 0.0000003 53 6279 49 0.0078038 0.9245283 REAC:R-HSA-9725370 REAC Signaling by ALK fusions and activated point mutants 10777 2095 REAC:R-H…. query_1 TRUE 0.0000003 32 6279 32 0.0050964 1.0000000 REAC:R-HSA-69190 REAC DNA strand elongation 10777 428 REAC:R-H…. query_1 TRUE 0.0000003 117 6279 96 0.0152891 0.8205128 REAC:R-HSA-2408522 REAC Selenoamino acid metabolism 10777 2064 REAC:R-H…. query_1 TRUE 0.0000004 38 6279 37 0.0058927 0.9736842 REAC:R-HSA-9675126 REAC Diseases of mitotic cell cycle 10777 731 REAC:R-H…. query_1 TRUE 0.0000004 38 6279 37 0.0058927 0.9736842 REAC:R-HSA-5696394 REAC DNA Damage Recognition in GG-NER 10777 418 REAC:R-H…. query_1 TRUE 0.0000004 140 6279 112 0.0178372 0.8000000 REAC:R-HSA-73887 REAC Death Receptor Signaling 10777 434 REAC:R-H…. query_1 TRUE 0.0000004 57 6279 52 0.0082816 0.9122807 REAC:R-HSA-75955 REAC RNA Polymerase II Transcription Elongation 10777 1799 REAC:R-H…. query_1 TRUE 0.0000004 57 6279 52 0.0082816 0.9122807 REAC:R-HSA-112382 REAC Formation of RNA Pol II elongation complex 10777 903 REAC:R-H…. query_1 TRUE 0.0000004 197 6279 151 0.0240484 0.7664975 REAC:R-HSA-9705683 REAC SARS-CoV-2-host interactions 10777 2006 REAC:R-H…. query_1 TRUE 0.0000004 43 6279 41 0.0065297 0.9534884 REAC:R-HSA-4615885 REAC SUMOylation of DNA replication proteins 10777 2047 REAC:R-H…. query_1 TRUE 0.0000004 43 6279 41 0.0065297 0.9534884 REAC:R-HSA-5696395 REAC Formation of Incision Complex in GG-NER 10777 902 REAC:R-H…. query_1 TRUE 0.0000004 43 6279 41 0.0065297 0.9534884 REAC:R-HSA-5693579 REAC Homologous DNA Pairing and Strand Exchange 10777 1070 REAC:R-H…. query_1 TRUE 0.0000004 61 6279 55 0.0087594 0.9016393 REAC:R-HSA-5678895 REAC Defective CFTR causes cystic fibrosis 10777 484 REAC:R-H…. query_1 TRUE 0.0000005 52 6279 48 0.0076445 0.9230769 REAC:R-HSA-75815 REAC Ubiquitin-dependent degradation of Cyclin D 10777 2482 REAC:R-H…. query_1 TRUE 0.0000005 52 6279 48 0.0076445 0.9230769 REAC:R-HSA-69613 REAC p53-Independent G1/S DNA damage checkpoint 10777 2579 REAC:R-H…. query_1 TRUE 0.0000005 52 6279 48 0.0076445 0.9230769 REAC:R-HSA-69610 REAC p53-Independent DNA Damage Response 10777 2578 REAC:R-H…. query_1 TRUE 0.0000005 52 6279 48 0.0076445 0.9230769 REAC:R-HSA-69601 REAC Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 10777 2481 REAC:R-H…. query_1 TRUE 0.0000005 52 6279 48 0.0076445 0.9230769 REAC:R-HSA-72695 REAC Formation of the ternary complex, and subsequently, the 43S complex 10777 920 REAC:R-H…. query_1 TRUE 0.0000005 91 6279 77 0.0122631 0.8461538 REAC:R-HSA-168181 REAC Toll Like Receptor 7/8 (TLR7/8) Cascade 10777 2385 REAC:R-H…. query_1 TRUE 0.0000006 37 6279 36 0.0057334 0.9729730 REAC:R-HSA-5685938 REAC HDR through Single Strand Annealing (SSA) 10777 1042 REAC:R-H…. query_1 TRUE 0.0000006 37 6279 36 0.0057334 0.9729730 REAC:R-HSA-176187 REAC Activation of ATR in response to replication stress 10777 71 REAC:R-H…. query_1 TRUE 0.0000006 47 6279 44 0.0070075 0.9361702 REAC:R-HSA-2980766 REAC Nuclear Envelope Breakdown 10777 1527 REAC:R-H…. query_1 TRUE 0.0000006 60 6279 54 0.0086001 0.9000000 REAC:R-HSA-5610783 REAC Degradation of GLI2 by the proteasome 10777 689 REAC:R-H…. query_1 TRUE 0.0000006 60 6279 54 0.0086001 0.9000000 REAC:R-HSA-5610785 REAC GLI3 is processed to GLI3R by the proteasome 10777 962 REAC:R-H…. query_1 TRUE 0.0000007 64 6279 57 0.0090779 0.8906250 REAC:R-HSA-4608870 REAC Asymmetric localization of PCP proteins 10777 177 REAC:R-H…. query_1 TRUE 0.0000008 51 6279 47 0.0074853 0.9215686 REAC:R-HSA-350562 REAC Regulation of ornithine decarboxylase (ODC) 10777 1931 REAC:R-H…. query_1 TRUE 0.0000008 51 6279 47 0.0074853 0.9215686 REAC:R-HSA-72165 REAC mRNA Splicing - Minor Pathway 10777 2567 REAC:R-H…. query_1 TRUE 0.0000009 55 6279 50 0.0079631 0.9090909 REAC:R-HSA-4641257 REAC Degradation of AXIN 10777 685 REAC:R-H…. query_1 TRUE 0.0000009 30 6279 30 0.0047778 1.0000000 REAC:R-HSA-8866652 REAC Synthesis of active ubiquitin: roles of E1 and E2 enzymes 10777 2270 REAC:R-H…. query_1 TRUE 0.0000009 30 6279 30 0.0047778 1.0000000 REAC:R-HSA-110314 REAC Recognition of DNA damage by PCNA-containing replication complex 10777 1855 REAC:R-H…. query_1 TRUE 0.0000009 55 6279 50 0.0079631 0.9090909 REAC:R-HSA-8854050 REAC FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 10777 846 REAC:R-H…. query_1 TRUE 0.0000009 36 6279 35 0.0055741 0.9722222 REAC:R-HSA-73933 REAC Resolution of Abasic Sites (AP sites) 10777 1958 REAC:R-H…. query_1 TRUE 0.0000009 36 6279 35 0.0055741 0.9722222 REAC:R-HSA-9687139 REAC Aberrant regulation of mitotic cell cycle due to RB1 defects 10777 44 REAC:R-H…. query_1 TRUE 0.0000009 46 6279 43 0.0068482 0.9347826 REAC:R-HSA-2173793 REAC Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 10777 2417 REAC:R-H…. query_1 TRUE 0.0000009 59 6279 53 0.0084408 0.8983051 REAC:R-HSA-5387390 REAC Hh mutants abrogate ligand secretion 10777 1063 REAC:R-H…. query_1 TRUE 0.0000009 59 6279 53 0.0084408 0.8983051 REAC:R-HSA-6790901 REAC rRNA modification in the nucleus and cytosol 10777 2590 REAC:R-H…. query_1 TRUE 0.0000010 41 6279 39 0.0062112 0.9512195 REAC:R-HSA-9675136 REAC Diseases of DNA Double-Strand Break Repair 10777 720 REAC:R-H…. query_1 TRUE 0.0000010 41 6279 39 0.0062112 0.9512195 REAC:R-HSA-165159 REAC MTOR signalling 10777 1317 REAC:R-H…. query_1 TRUE 0.0000010 41 6279 39 0.0062112 0.9512195 REAC:R-HSA-3899300 REAC SUMOylation of transcription cofactors 10777 2054 REAC:R-H…. query_1 TRUE 0.0000010 41 6279 39 0.0062112 0.9512195 REAC:R-HSA-5696400 REAC Dual Incision in GG-NER 10777 769 REAC:R-H…. query_1 TRUE 0.0000010 41 6279 39 0.0062112 0.9512195 REAC:R-HSA-9701190 REAC Defective homologous recombination repair (HRR) due to BRCA2 loss of function 10777 674 REAC:R-H…. query_1 TRUE 0.0000011 89 6279 75 0.0119446 0.8426966 REAC:R-HSA-5687128 REAC MAPK6/MAPK4 signaling 10777 1287 REAC:R-H…. query_1 TRUE 0.0000011 50 6279 46 0.0073260 0.9200000 REAC:R-HSA-211733 REAC Regulation of activated PAK-2p34 by proteasome mediated degradation 10777 1910 REAC:R-H…. query_1 TRUE 0.0000012 149 6279 117 0.0186335 0.7852349 REAC:R-HSA-8980692 REAC RHOA GTPase cycle 10777 1767 REAC:R-H…. query_1 TRUE 0.0000012 177 6279 136 0.0216595 0.7683616 REAC:R-HSA-1428517 REAC The citric acid (TCA) cycle and respiratory electron transport 10777 2365 REAC:R-H…. query_1 TRUE 0.0000013 92 6279 77 0.0122631 0.8369565 REAC:R-HSA-4086400 REAC PCP/CE pathway 10777 1571 REAC:R-H…. query_1 TRUE 0.0000013 54 6279 49 0.0078038 0.9074074 REAC:R-HSA-450408 REAC AUF1 (hnRNP D0) binds and destabilizes mRNA 10777 36 REAC:R-H…. query_1 TRUE 0.0000013 116 6279 94 0.0149705 0.8103448 REAC:R-HSA-9006936 REAC Signaling by TGFB family members 10777 2185 REAC:R-H…. query_1 TRUE 0.0000014 35 6279 34 0.0054149 0.9714286 REAC:R-HSA-9709570 REAC Impaired BRCA2 binding to RAD51 10777 1113 REAC:R-H…. query_1 TRUE 0.0000015 88 6279 74 0.0117853 0.8409091 REAC:R-HSA-8876198 REAC RAB GEFs exchange GTP for GDP on RABs 10777 1742 REAC:R-H…. query_1 TRUE 0.0000015 95 6279 79 0.0125816 0.8315789 REAC:R-HSA-380320 REAC Recruitment of NuMA to mitotic centrosomes 10777 1857 REAC:R-H…. query_1 TRUE 0.0000015 40 6279 38 0.0060519 0.9500000 REAC:R-HSA-168325 REAC Viral Messenger RNA Synthesis 10777 2509 REAC:R-H…. query_1 TRUE 0.0000015 40 6279 38 0.0060519 0.9500000 REAC:R-HSA-5693616 REAC Presynaptic phase of homologous DNA pairing and strand exchange 10777 1703 REAC:R-H…. query_1 TRUE 0.0000017 49 6279 45 0.0071667 0.9183673 REAC:R-HSA-381070 REAC IRE1alpha activates chaperones 10777 1100 REAC:R-H…. query_1 TRUE 0.0000019 53 6279 48 0.0076445 0.9056604 REAC:R-HSA-180585 REAC Vif-mediated degradation of APOBEC3G 10777 2508 REAC:R-H…. query_1 TRUE 0.0000021 57 6279 51 0.0081223 0.8947368 REAC:R-HSA-69541 REAC Stabilization of p53 10777 2221 REAC:R-H…. query_1 TRUE 0.0000021 57 6279 51 0.0081223 0.8947368 REAC:R-HSA-4641258 REAC Degradation of DVL 10777 686 REAC:R-H…. query_1 TRUE 0.0000021 87 6279 73 0.0116261 0.8390805 REAC:R-HSA-3371556 REAC Cellular response to heat stress 10777 322 REAC:R-H…. query_1 TRUE 0.0000023 34 6279 33 0.0052556 0.9705882 REAC:R-HSA-8953750 REAC Transcriptional Regulation by E2F6 10777 2410 REAC:R-H…. query_1 TRUE 0.0000023 28 6279 28 0.0044593 1.0000000 REAC:R-HSA-76071 REAC RNA Polymerase III Transcription Initiation From Type 3 Promoter 10777 1810 REAC:R-H…. query_1 TRUE 0.0000023 28 6279 28 0.0044593 1.0000000 REAC:R-HSA-76061 REAC RNA Polymerase III Transcription Initiation From Type 1 Promoter 10777 1808 REAC:R-H…. query_1 TRUE 0.0000024 39 6279 37 0.0058927 0.9487179 REAC:R-HSA-159234 REAC Transport of Mature mRNAs Derived from Intronless Transcripts 10777 2450 REAC:R-H…. query_1 TRUE 0.0000024 39 6279 37 0.0058927 0.9487179 REAC:R-HSA-110313 REAC Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 10777 2440 REAC:R-H…. query_1 TRUE 0.0000029 100 6279 82 0.0130594 0.8200000 REAC:R-HSA-168188 REAC Toll Like Receptor TLR6:TLR2 Cascade 10777 2388 REAC:R-H…. query_1 TRUE 0.0000029 100 6279 82 0.0130594 0.8200000 REAC:R-HSA-166058 REAC MyD88:MAL(TIRAP) cascade initiated on plasma membrane 10777 1421 REAC:R-H…. query_1 TRUE 0.0000029 133 6279 105 0.0167224 0.7894737 REAC:R-HSA-8856688 REAC Golgi-to-ER retrograde transport 10777 1027 REAC:R-H…. query_1 TRUE 0.0000029 64 6279 56 0.0089186 0.8750000 REAC:R-HSA-1834949 REAC Cytosolic sensors of pathogen-associated DNA 10777 407 REAC:R-H…. query_1 TRUE 0.0000029 52 6279 47 0.0074853 0.9038462 REAC:R-HSA-9678108 REAC SARS-CoV-1 Infection 10777 1992 REAC:R-H…. query_1 TRUE 0.0000029 52 6279 47 0.0074853 0.9038462 REAC:R-HSA-180534 REAC Vpu mediated degradation of CD4 10777 2527 REAC:R-H…. query_1 TRUE 0.0000029 52 6279 47 0.0074853 0.9038462 REAC:R-HSA-9013405 REAC RHOD GTPase cycle 10777 1774 REAC:R-H…. query_1 TRUE 0.0000029 52 6279 47 0.0074853 0.9038462 REAC:R-HSA-349425 REAC Autodegradation of the E3 ubiquitin ligase COP1 10777 184 REAC:R-H…. query_1 TRUE 0.0000030 60 6279 53 0.0084408 0.8833333 REAC:R-HSA-5610780 REAC Degradation of GLI1 by the proteasome 10777 688 REAC:R-H…. query_1 TRUE 0.0000033 43 6279 40 0.0063704 0.9302326 REAC:R-HSA-4570464 REAC SUMOylation of RNA binding proteins 10777 2048 REAC:R-H…. query_1 TRUE 0.0000034 297 6279 214 0.0340819 0.7205387 REAC:R-HSA-5688426 REAC Deubiquitination 10777 702 REAC:R-H…. query_1 TRUE 0.0000036 71 6279 61 0.0097149 0.8591549 REAC:R-HSA-8939902 REAC Regulation of RUNX2 expression and activity 10777 1897 REAC:R-H…. query_1 TRUE 0.0000036 33 6279 32 0.0050964 0.9696970 REAC:R-HSA-68962 REAC Activation of the pre-replicative complex 10777 103 REAC:R-H…. query_1 TRUE 0.0000037 27 6279 27 0.0043000 1.0000000 REAC:R-HSA-76066 REAC RNA Polymerase III Transcription Initiation From Type 2 Promoter 10777 1809 REAC:R-H…. query_1 TRUE 0.0000037 38 6279 36 0.0057334 0.9473684 REAC:R-HSA-159231 REAC Transport of Mature mRNA Derived from an Intronless Transcript 10777 2448 REAC:R-H…. query_1 TRUE 0.0000037 38 6279 36 0.0057334 0.9473684 REAC:R-HSA-390471 REAC Association of TriC/CCT with target proteins during biosynthesis 10777 175 REAC:R-H…. query_1 TRUE 0.0000039 47 6279 43 0.0068482 0.9148936 REAC:R-HSA-381038 REAC XBP1(S) activates chaperone genes 10777 2537 REAC:R-H…. query_1 TRUE 0.0000039 67 6279 58 0.0092371 0.8656716 REAC:R-HSA-400253 REAC Circadian Clock 10777 348 REAC:0000000 query_1 TRUE 0.0000039 47 6279 43 0.0068482 0.9148936 REAC:R-HSA-73762 REAC RNA Polymerase I Transcription Initiation 10777 1793 REAC:R-H…. query_1 TRUE 0.0000039 67 6279 58 0.0092371 0.8656716 REAC:R-HSA-3371453 REAC Regulation of HSF1-mediated heat shock response 10777 1878 REAC:R-H…. query_1 TRUE 0.0000039 67 6279 58 0.0092371 0.8656716 REAC:R-HSA-5658442 REAC Regulation of RAS by GAPs 10777 1895 REAC:R-H…. query_1 TRUE 0.0000042 51 6279 46 0.0073260 0.9019608 REAC:R-HSA-191859 REAC snRNP Assembly 10777 2595 REAC:R-H…. query_1 TRUE 0.0000042 51 6279 46 0.0073260 0.9019608 REAC:R-HSA-194441 REAC Metabolism of non-coding RNA 10777 1355 REAC:R-H…. query_1 TRUE 0.0000051 118 6279 94 0.0149705 0.7966102 REAC:R-HSA-8878166 REAC Transcriptional regulation by RUNX2 10777 2419 REAC:R-H…. query_1 TRUE 0.0000057 32 6279 31 0.0049371 0.9687500 REAC:R-HSA-113418 REAC Formation of the Early Elongation Complex 10777 914 REAC:R-H…. query_1 TRUE 0.0000057 32 6279 31 0.0049371 0.9687500 REAC:R-HSA-5656169 REAC Termination of translesion DNA synthesis 10777 2357 REAC:R-H…. query_1 TRUE 0.0000057 32 6279 31 0.0049371 0.9687500 REAC:R-HSA-167158 REAC Formation of the HIV-1 Early Elongation Complex 10777 916 REAC:R-H…. query_1 TRUE 0.0000058 46 6279 42 0.0066890 0.9130435 REAC:R-HSA-69236 REAC G1 Phase 10777 946 REAC:R-H…. query_1 TRUE 0.0000058 46 6279 42 0.0066890 0.9130435 REAC:R-HSA-167162 REAC RNA Polymerase II HIV Promoter Escape 10777 1795 REAC:R-H…. query_1 TRUE 0.0000058 46 6279 42 0.0066890 0.9130435 REAC:R-HSA-69231 REAC Cyclin D associated events in G1 10777 399 REAC:R-H…. query_1 TRUE 0.0000058 46 6279 42 0.0066890 0.9130435 REAC:R-HSA-73776 REAC RNA Polymerase II Promoter Escape 10777 1797 REAC:R-H…. query_1 TRUE 0.0000058 46 6279 42 0.0066890 0.9130435 REAC:R-HSA-167161 REAC HIV Transcription Initiation 10777 1047 REAC:R-H…. query_1 TRUE 0.0000058 46 6279 42 0.0066890 0.9130435 REAC:R-HSA-75953 REAC RNA Polymerase II Transcription Initiation 10777 1800 REAC:R-H…. query_1 TRUE 0.0000058 46 6279 42 0.0066890 0.9130435 REAC:R-HSA-76042 REAC RNA Polymerase II Transcription Initiation And Promoter Clearance 10777 1801 REAC:R-H…. query_1 TRUE 0.0000058 46 6279 42 0.0066890 0.9130435 REAC:R-HSA-73779 REAC RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 10777 1802 REAC:R-H…. query_1 TRUE 0.0000063 58 6279 51 0.0081223 0.8793103 REAC:R-HSA-351202 REAC Metabolism of polyamines 10777 1357 REAC:R-H…. query_1 TRUE 0.0000064 54 6279 48 0.0076445 0.8888889 REAC:R-HSA-432722 REAC Golgi Associated Vesicle Biogenesis 10777 1025 REAC:R-H…. query_1 TRUE 0.0000064 54 6279 48 0.0076445 0.8888889 REAC:R-HSA-71406 REAC Pyruvate metabolism and Citric Acid (TCA) cycle 10777 1740 REAC:R-H…. query_1 TRUE 0.0000072 167 6279 127 0.0202262 0.7604790 REAC:R-HSA-69481 REAC G2/M Checkpoints 10777 951 REAC:R-H…. query_1 TRUE 0.0000088 154 6279 118 0.0187928 0.7662338 REAC:R-HSA-168898 REAC Toll-like Receptor Cascades 10777 2389 REAC:R-H…. query_1 TRUE 0.0000089 103 6279 83 0.0132187 0.8058252 REAC:R-HSA-168179 REAC Toll Like Receptor TLR1:TLR2 Cascade 10777 2387 REAC:R-H…. query_1 TRUE 0.0000089 103 6279 83 0.0132187 0.8058252 REAC:R-HSA-181438 REAC Toll Like Receptor 2 (TLR2) Cascade 10777 2381 REAC:R-H…. query_1 TRUE 0.0000091 132 6279 103 0.0164039 0.7803030 REAC:R-HSA-166016 REAC Toll Like Receptor 4 (TLR4) Cascade 10777 2383 REAC:R-H…. query_1 TRUE 0.0000092 57 6279 50 0.0079631 0.8771930 REAC:R-HSA-2894862 REAC Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 10777 383 REAC:R-H…. query_1 TRUE 0.0000092 57 6279 50 0.0079631 0.8771930 REAC:R-HSA-2644606 REAC Constitutive Signaling by NOTCH1 PEST Domain Mutants 10777 384 REAC:R-H…. query_1 TRUE 0.0000092 57 6279 50 0.0079631 0.8771930 REAC:R-HSA-2644603 REAC Signaling by NOTCH1 in Cancer 10777 2154 REAC:R-H…. query_1 TRUE 0.0000092 57 6279 50 0.0079631 0.8771930 REAC:R-HSA-2644602 REAC Signaling by NOTCH1 PEST Domain Mutants in Cancer 10777 2153 REAC:R-H…. query_1 TRUE 0.0000092 57 6279 50 0.0079631 0.8771930 REAC:R-HSA-2894858 REAC Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 10777 2152 REAC:R-H…. query_1 TRUE 0.0000097 25 6279 25 0.0039815 1.0000000 REAC:R-HSA-5696397 REAC Gap-filling DNA repair synthesis and ligation in GG-NER 10777 983 REAC:R-H…. query_1 TRUE 0.0000097 25 6279 25 0.0039815 1.0000000 REAC:R-HSA-6803529 REAC FGFR2 alternative splicing 10777 859 REAC:R-H…. query_1 TRUE 0.0000136 44 6279 40 0.0063704 0.9090909 REAC:R-HSA-5633008 REAC TP53 Regulates Transcription of Cell Death Genes 10777 2320 REAC:R-H…. query_1 TRUE 0.0000136 44 6279 40 0.0063704 0.9090909 REAC:R-HSA-167152 REAC Formation of HIV elongation complex in the absence of HIV Tat 10777 900 REAC:R-H…. query_1 TRUE 0.0000142 35 6279 33 0.0052556 0.9428571 REAC:R-HSA-3232142 REAC SUMOylation of ubiquitinylation proteins 10777 2056 REAC:R-H…. query_1 TRUE 0.0000142 35 6279 33 0.0052556 0.9428571 REAC:R-HSA-936440 REAC Negative regulators of DDX58/IFIH1 signaling 10777 1496 REAC:R-H…. query_1 TRUE 0.0000142 35 6279 33 0.0052556 0.9428571 REAC:R-HSA-9706574 REAC RHOBTB GTPase Cycle 10777 1769 REAC:R-H…. query_1 TRUE 0.0000144 30 6279 29 0.0046186 0.9666667 REAC:R-HSA-6804758 REAC Regulation of TP53 Activity through Acetylation 10777 1902 REAC:R-H…. query_1 TRUE 0.0000147 88 6279 72 0.0114668 0.8181818 REAC:R-HSA-9013404 REAC RAC2 GTPase cycle 10777 1745 REAC:R-H…. query_1 TRUE 0.0000163 24 6279 24 0.0038223 1.0000000 REAC:R-HSA-174048 REAC APC/C:Cdc20 mediated degradation of Cyclin B 10777 22 REAC:R-H…. query_1 TRUE 0.0000163 24 6279 24 0.0038223 1.0000000 REAC:R-HSA-2173788 REAC Downregulation of TGF-beta receptor signaling 10777 750 REAC:R-H…. query_1 TRUE 0.0000175 139 6279 107 0.0170409 0.7697842 REAC:R-HSA-446652 REAC Interleukin-1 family signaling 10777 1171 REAC:R-H…. query_1 TRUE 0.0000179 84 6279 69 0.0109890 0.8214286 REAC:R-HSA-70326 REAC Glucose metabolism 10777 999 REAC:R-H…. query_1 TRUE 0.0000186 59 6279 51 0.0081223 0.8644068 REAC:R-HSA-9013406 REAC RHOQ GTPase cycle 10777 1779 REAC:R-H…. query_1 TRUE 0.0000213 51 6279 45 0.0071667 0.8823529 REAC:R-HSA-180786 REAC Extension of Telomeres 10777 842 REAC:R-H…. query_1 TRUE 0.0000213 51 6279 45 0.0071667 0.8823529 REAC:R-HSA-9754678 REAC SARS-CoV-2 modulates host translation machinery 10777 2003 REAC:R-H…. query_1 TRUE 0.0000220 113 6279 89 0.0141742 0.7876106 REAC:R-HSA-5610787 REAC Hedgehog ‘off’ state 10777 1054 REAC:R-H…. query_1 TRUE 0.0000223 34 6279 32 0.0050964 0.9411765 REAC:R-HSA-177243 REAC Interactions of Rev with host cellular proteins 10777 1161 REAC:R-H…. query_1 TRUE 0.0000231 29 6279 28 0.0044593 0.9655172 REAC:R-HSA-380972 REAC Energy dependent regulation of mTOR by LKB1-AMPK 10777 805 REAC:R-H…. query_1 TRUE 0.0000272 23 6279 23 0.0036630 1.0000000 REAC:R-HSA-203927 REAC MicroRNA (miRNA) biogenesis 10777 1373 REAC:R-H…. query_1 TRUE 0.0000283 38 6279 35 0.0055741 0.9210526 REAC:R-HSA-168276 REAC NS1 Mediated Effects on Host Pathways 10777 1465 REAC:R-H…. query_1 TRUE 0.0000287 1051 6279 680 0.1082975 0.6470029 REAC:R-HSA-5663205 REAC Infectious disease 10777 1123 REAC:R-H…. query_1 TRUE 0.0000305 65 6279 55 0.0087594 0.8461538 REAC:R-HSA-5358346 REAC Hedgehog ligand biogenesis 10777 1056 REAC:R-H…. query_1 TRUE 0.0000312 42 6279 38 0.0060519 0.9047619 REAC:R-HSA-9696273 REAC RND1 GTPase cycle 10777 1813 REAC:R-H…. query_1 TRUE 0.0000312 42 6279 38 0.0060519 0.9047619 REAC:R-HSA-167246 REAC Tat-mediated elongation of the HIV-1 transcript 10777 2350 REAC:R-H…. query_1 TRUE 0.0000312 42 6279 38 0.0060519 0.9047619 REAC:R-HSA-167200 REAC Formation of HIV-1 elongation complex containing HIV-1 Tat 10777 901 REAC:R-H…. query_1 TRUE 0.0000312 42 6279 38 0.0060519 0.9047619 REAC:R-HSA-167169 REAC HIV Transcription Elongation 10777 1046 REAC:R-H…. query_1 TRUE 0.0000350 33 6279 31 0.0049371 0.9393939 REAC:R-HSA-3301854 REAC Nuclear Pore Complex (NPC) Disassembly 10777 1529 REAC:R-H…. query_1 TRUE 0.0000350 33 6279 31 0.0049371 0.9393939 REAC:R-HSA-2559585 REAC Oncogene Induced Senescence 10777 1552 REAC:R-H…. query_1 TRUE 0.0000370 28 6279 27 0.0043000 0.9642857 REAC:R-HSA-5213460 REAC RIPK1-mediated regulated necrosis 10777 1785 REAC:R-H…. query_1 TRUE 0.0000370 28 6279 27 0.0043000 0.9642857 REAC:R-HSA-72086 REAC mRNA Capping 10777 2561 REAC:R-H…. query_1 TRUE 0.0000370 28 6279 27 0.0043000 0.9642857 REAC:R-HSA-5675482 REAC Regulation of necroptotic cell death 10777 1930 REAC:R-H…. query_1 TRUE 0.0000434 37 6279 34 0.0054149 0.9189189 REAC:R-HSA-9013424 REAC RHOV GTPase cycle 10777 1783 REAC:R-H…. query_1 TRUE 0.0000448 22 6279 22 0.0035037 1.0000000 REAC:R-HSA-167242 REAC Abortive elongation of HIV-1 transcript in the absence of Tat 10777 47 REAC:R-H…. query_1 TRUE 0.0000448 22 6279 22 0.0035037 1.0000000 REAC:R-HSA-71403 REAC Citric acid cycle (TCA cycle) 10777 349 REAC:R-H…. query_1 TRUE 0.0000467 49 6279 43 0.0068482 0.8775510 REAC:R-HSA-6811440 REAC Retrograde transport at the Trans-Golgi-Network 10777 1974 REAC:R-H…. query_1 TRUE 0.0000549 32 6279 30 0.0047778 0.9375000 REAC:R-HSA-159230 REAC Transport of the SLBP Dependant Mature mRNA 10777 2464 REAC:R-H…. query_1 TRUE 0.0000549 32 6279 30 0.0047778 0.9375000 REAC:R-HSA-165054 REAC Rev-mediated nuclear export of HIV RNA 10777 1976 REAC:R-H…. query_1 TRUE 0.0000549 32 6279 30 0.0047778 0.9375000 REAC:R-HSA-4085377 REAC SUMOylation of SUMOylation proteins 10777 2049 REAC:R-H…. query_1 TRUE 0.0000549 32 6279 30 0.0047778 0.9375000 REAC:R-HSA-2173796 REAC SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 10777 2031 REAC:R-H…. query_1 TRUE 0.0000599 27 6279 26 0.0041408 0.9629630 REAC:R-HSA-69205 REAC G1/S-Specific Transcription 10777 949 REAC:R-H…. query_1 TRUE 0.0000602 549 6279 368 0.0586081 0.6703097 REAC:R-HSA-422475 REAC Axon guidance 10777 187 REAC:R-H…. query_1 TRUE 0.0000616 70 6279 58 0.0092371 0.8285714 REAC:R-HSA-2995410 REAC Nuclear Envelope (NE) Reassembly 10777 1526 REAC:R-H…. query_1 TRUE 0.0000727 44 6279 39 0.0062112 0.8863636 REAC:R-HSA-2173789 REAC TGF-beta receptor signaling activates SMADs 10777 2298 REAC:R-H…. query_1 TRUE 0.0000743 66 6279 55 0.0087594 0.8333333 REAC:R-HSA-70171 REAC Glycolysis 10777 1020 REAC:R-H…. query_1 TRUE 0.0000746 21 6279 21 0.0033445 1.0000000 REAC:R-HSA-5651801 REAC PCNA-Dependent Long Patch Base Excision Repair 10777 1570 REAC:R-H…. query_1 TRUE 0.0000753 574 6279 383 0.0609970 0.6672474 REAC:R-HSA-9675108 REAC Nervous system development 10777 1498 REAC:R-H…. query_1 TRUE 0.0000765 502 6279 338 0.0538302 0.6733068 REAC:R-HSA-9006934 REAC Signaling by Receptor Tyrosine Kinases 10777 2177 REAC:R-H…. query_1 TRUE 0.0000788 184 6279 135 0.0215002 0.7336957 REAC:R-HSA-9013149 REAC RAC1 GTPase cycle 10777 1744 REAC:R-H…. query_1 TRUE 0.0000821 55 6279 47 0.0074853 0.8545455 REAC:R-HSA-9013409 REAC RHOJ GTPase cycle 10777 1778 REAC:R-H…. query_1 TRUE 0.0000821 55 6279 47 0.0074853 0.8545455 REAC:R-HSA-5218859 REAC Regulated Necrosis 10777 1866 REAC:R-H…. query_1 TRUE 0.0000846 369 6279 254 0.0404523 0.6883469 REAC:R-HSA-71291 REAC Metabolism of amino acids and derivatives 10777 1345 REAC:R-H…. query_1 TRUE 0.0000848 31 6279 29 0.0046186 0.9354839 REAC:R-HSA-180746 REAC Nuclear import of Rev protein 10777 1533 REAC:R-H…. query_1 TRUE 0.0000848 31 6279 29 0.0046186 0.9354839 REAC:R-HSA-450282 REAC MAPK targets/ Nuclear events mediated by MAP kinases 10777 1283 REAC:R-H…. query_1 TRUE 0.0000848 31 6279 29 0.0046186 0.9354839 REAC:R-HSA-180910 REAC Vpr-mediated nuclear import of PICs 10777 2526 REAC:R-H…. query_1 TRUE 0.0000848 31 6279 29 0.0046186 0.9354839 REAC:R-HSA-159227 REAC Transport of the SLBP independent Mature mRNA 10777 2465 REAC:R-H…. query_1 TRUE 0.0000848 31 6279 29 0.0046186 0.9354839 REAC:R-HSA-917729 REAC Endosomal Sorting Complex Required For Transport (ESCRT) 10777 803 REAC:R-H…. query_1 TRUE 0.0000861 62 6279 52 0.0082816 0.8387097 REAC:R-HSA-9707564 REAC Cytoprotection by HMOX1 10777 405 REAC:R-H…. query_1 TRUE 0.0000891 79 6279 64 0.0101927 0.8101266 REAC:R-HSA-8852276 REAC The role of GTSE1 in G2/M progression after G2 checkpoint 10777 2370 REAC:R-H…. query_1 TRUE 0.0000935 26 6279 25 0.0039815 0.9615385 REAC:R-HSA-167160 REAC RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 10777 1788 REAC:R-H…. query_1 TRUE 0.0000935 26 6279 25 0.0039815 0.9615385 REAC:R-HSA-77075 REAC RNA Pol II CTD phosphorylation and interaction with CE 10777 1787 REAC:R-H…. query_1 TRUE 0.0000935 26 6279 25 0.0039815 0.9615385 REAC:R-HSA-179409 REAC APC-Cdc20 mediated degradation of Nek2A 10777 20 REAC:R-H…. query_1 TRUE 0.0000935 26 6279 25 0.0039815 0.9615385 REAC:R-HSA-1538133 REAC G0 and Early G1 10777 945 REAC:R-H…. query_1 TRUE 0.0000999 35 6279 32 0.0050964 0.9142857 REAC:R-HSA-532668 REAC N-glycan trimming in the ER and Calnexin/Calreticulin cycle 10777 1427 REAC:R-H…. query_1 TRUE 0.0001046 168 6279 124 0.0197484 0.7380952 REAC:R-HSA-5693532 REAC DNA Double-Strand Break Repair 10777 422 REAC:R-H…. query_1 TRUE 0.0001050 43 6279 38 0.0060519 0.8837209 REAC:R-HSA-9696270 REAC RND2 GTPase cycle 10777 1814 REAC:R-H…. query_1 TRUE 0.0001058 39 6279 35 0.0055741 0.8974359 REAC:R-HSA-5689896 REAC Ovarian tumor domain proteases 10777 1565 REAC:R-H…. query_1 TRUE 0.0001089 101 6279 79 0.0125816 0.7821782 REAC:R-HSA-5689603 REAC UCH proteinases 10777 2477 REAC:R-H…. query_1 TRUE 0.0001098 144 6279 108 0.0172002 0.7500000 REAC:R-HSA-8856828 REAC Clathrin-mediated endocytosis 10777 357 REAC:R-H…. query_1 TRUE 0.0001196 20 6279 20 0.0031852 1.0000000 REAC:R-HSA-9687136 REAC Aberrant regulation of mitotic exit in cancer due to RB1 defects 10777 45 REAC:R-H…. query_1 TRUE 0.0001196 20 6279 20 0.0031852 1.0000000 REAC:R-HSA-69186 REAC Lagging Strand Synthesis 10777 1240 REAC:R-H…. query_1 TRUE 0.0001196 20 6279 20 0.0031852 1.0000000 REAC:R-HSA-176412 REAC Phosphorylation of the APC/C 10777 1663 REAC:R-H…. query_1 TRUE 0.0001206 78 6279 63 0.0100334 0.8076923 REAC:R-HSA-8852135 REAC Protein ubiquitination 10777 1725 REAC:R-H…. query_1 TRUE 0.0001305 94 6279 74 0.0117853 0.7872340 REAC:R-HSA-9013423 REAC RAC3 GTPase cycle 10777 1746 REAC:R-H…. query_1 TRUE 0.0001305 30 6279 28 0.0044593 0.9333333 REAC:R-HSA-114452 REAC Activation of BH3-only proteins 10777 73 REAC:R-H…. query_1 TRUE 0.0001370 155 6279 115 0.0183150 0.7419355 REAC:R-HSA-9013148 REAC CDC42 GTPase cycle 10777 258 REAC:R-H…. query_1 TRUE 0.0001373 97 6279 76 0.0121038 0.7835052 REAC:R-HSA-193704 REAC p75 NTR receptor-mediated signalling 10777 2580 REAC:R-H…. query_1 TRUE 0.0001384 149 6279 111 0.0176780 0.7449664 REAC:R-HSA-5358351 REAC Signaling by Hedgehog 10777 2135 REAC:R-H…. query_1 TRUE 0.0001413 57 6279 48 0.0076445 0.8421053 REAC:R-HSA-6799198 REAC Complex I biogenesis 10777 371 REAC:R-H…. query_1 TRUE 0.0001436 46 6279 40 0.0063704 0.8695652 REAC:R-HSA-2122947 REAC NOTCH1 Intracellular Domain Regulates Transcription 10777 1447 REAC:R-H…. query_1 TRUE 0.0001464 25 6279 24 0.0038223 0.9600000 REAC:R-HSA-110373 REAC Resolution of AP sites via the multiple-nucleotide patch replacement pathway 10777 1956 REAC:R-H…. query_1 TRUE 0.0001464 25 6279 24 0.0038223 0.9600000 REAC:R-HSA-9701193 REAC Defective homologous recombination repair (HRR) due to PALB2 loss of function 10777 675 REAC:R-H…. query_1 TRUE 0.0001464 25 6279 24 0.0038223 0.9600000 REAC:R-HSA-9704646 REAC Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function 10777 542 REAC:R-H…. query_1 TRUE 0.0001464 25 6279 24 0.0038223 0.9600000 REAC:R-HSA-9704331 REAC Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function 10777 541 REAC:R-H…. query_1 TRUE 0.0001464 25 6279 24 0.0038223 0.9600000 REAC:R-HSA-9701192 REAC Defective homologous recombination repair (HRR) due to BRCA1 loss of function 10777 673 REAC:R-H…. query_1 TRUE 0.0001467 74 6279 60 0.0095557 0.8108108 REAC:R-HSA-9013408 REAC RHOG GTPase cycle 10777 1776 REAC:R-H…. query_1 TRUE 0.0001480 34 6279 31 0.0049371 0.9117647 REAC:R-HSA-5693568 REAC Resolution of D-loop Structures through Holliday Junction Intermediates 10777 1960 REAC:R-H…. query_1 TRUE 0.0001480 34 6279 31 0.0049371 0.9117647 REAC:R-HSA-174417 REAC Telomere C-strand (Lagging Strand) Synthesis 10777 2351 REAC:R-H…. query_1 TRUE 0.0001480 34 6279 31 0.0049371 0.9117647 REAC:R-HSA-176033 REAC Interactions of Vpr with host cellular proteins 10777 1163 REAC:R-H…. query_1 TRUE 0.0001502 42 6279 37 0.0058927 0.8809524 REAC:R-HSA-9035034 REAC RHOF GTPase cycle 10777 1775 REAC:R-H…. query_1 TRUE 0.0001502 42 6279 37 0.0058927 0.8809524 REAC:R-HSA-9696264 REAC RND3 GTPase cycle 10777 1815 REAC:R-H…. query_1 TRUE 0.0001502 42 6279 37 0.0058927 0.8809524 REAC:R-HSA-5675221 REAC Negative regulation of MAPK pathway 10777 1488 REAC:R-H…. query_1 TRUE 0.0001754 136 6279 102 0.0162446 0.7500000 REAC:R-HSA-5621481 REAC C-type lectin receptors (CLRs) 10777 249 REAC:R-H…. query_1 TRUE 0.0001941 19 6279 19 0.0030260 1.0000000 REAC:R-HSA-2028269 REAC Signaling by Hippo 10777 2136 REAC:R-H…. query_1 TRUE 0.0001941 19 6279 19 0.0030260 1.0000000 REAC:R-HSA-174414 REAC Processive synthesis on the C-strand of the telomere 10777 1711 REAC:R-H…. query_1 TRUE 0.0001972 273 6279 191 0.0304189 0.6996337 REAC:R-HSA-3247509 REAC Chromatin modifying enzymes 10777 340 REAC:R-H…. query_1 TRUE 0.0001972 273 6279 191 0.0304189 0.6996337 REAC:R-HSA-4839726 REAC Chromatin organization 10777 341 REAC:0000000 query_1 TRUE 0.0001974 29 6279 27 0.0043000 0.9310345 REAC:R-HSA-9683701 REAC Translation of Structural Proteins 10777 2434 REAC:R-H…. query_1 TRUE 0.0001974 29 6279 27 0.0043000 0.9310345 REAC:R-HSA-168333 REAC NEP/NS2 Interacts with the Cellular Export Machinery 10777 1433 REAC:R-H…. query_1 TRUE 0.0001974 29 6279 27 0.0043000 0.9310345 REAC:R-HSA-168271 REAC Transport of Ribonucleoproteins into the Host Nucleus 10777 2452 REAC:R-H…. query_1 TRUE 0.0001989 284 6279 198 0.0315337 0.6971831 REAC:R-HSA-71387 REAC Metabolism of carbohydrates 10777 1346 REAC:R-H…. query_1 TRUE 0.0002232 41 6279 36 0.0057334 0.8780488 REAC:R-HSA-6782315 REAC tRNA modification in the nucleus and cytosol 10777 2601 REAC:R-H…. query_1 TRUE 0.0002302 24 6279 23 0.0036630 0.9583333 REAC:R-HSA-9615933 REAC Postmitotic nuclear pore complex (NPC) reformation 10777 1688 REAC:R-H…. query_1 TRUE 0.0002302 37 6279 33 0.0052556 0.8918919 REAC:R-HSA-9694548 REAC Maturation of spike protein 10777 1333 REAC:R-H…. query_1 TRUE 0.0002302 24 6279 23 0.0036630 0.9583333 REAC:R-HSA-9709603 REAC Impaired BRCA2 binding to PALB2 10777 1112 REAC:R-H…. query_1 TRUE 0.0002302 24 6279 23 0.0036630 0.9583333 REAC:R-HSA-166208 REAC mTORC1-mediated signalling 10777 2570 REAC:R-H…. query_1 TRUE 0.0002552 82 6279 65 0.0103520 0.7926829 REAC:R-HSA-381340 REAC Transcriptional regulation of white adipocyte differentiation 10777 2426 REAC:R-H…. query_1 TRUE 0.0002738 72 6279 58 0.0092371 0.8055556 REAC:R-HSA-1980143 REAC Signaling by NOTCH1 10777 2150 REAC:R-H…. query_1 TRUE 0.0003010 44 6279 38 0.0060519 0.8636364 REAC:R-HSA-8854214 REAC TBC/RABGAPs 10777 2290 REAC:R-H…. query_1 TRUE 0.0003010 91 6279 71 0.0113075 0.7802198 REAC:R-HSA-15869 REAC Metabolism of nucleotides 10777 1356 REAC:R-H…. query_1 TRUE 0.0003010 44 6279 38 0.0060519 0.8636364 REAC:R-HSA-6811438 REAC Intra-Golgi traffic 10777 1203 REAC:R-H…. query_1 TRUE 0.0003051 65 6279 53 0.0084408 0.8153846 REAC:R-HSA-1268020 REAC Mitochondrial protein import 10777 1390 REAC:R-H…. query_1 TRUE 0.0003060 28 6279 26 0.0041408 0.9285714 REAC:R-HSA-75067 REAC Processing of Capped Intronless Pre-mRNA 10777 1707 REAC:R-H…. query_1 TRUE 0.0003060 28 6279 26 0.0041408 0.9285714 REAC:R-HSA-350054 REAC Notch-HLH transcription pathway 10777 1524 REAC:R-H…. query_1 TRUE 0.0003060 28 6279 26 0.0041408 0.9285714 REAC:R-HSA-162588 REAC Budding and maturation of HIV virion 10777 246 REAC:R-H…. query_1 TRUE 0.0003158 18 6279 18 0.0028667 1.0000000 REAC:R-HSA-73780 REAC RNA Polymerase III Chain Elongation 10777 1805 REAC:R-H…. query_1 TRUE 0.0003158 18 6279 18 0.0028667 1.0000000 REAC:R-HSA-6804114 REAC TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 10777 2325 REAC:R-H…. query_1 TRUE 0.0003158 18 6279 18 0.0028667 1.0000000 REAC:R-HSA-1362277 REAC Transcription of E2F targets under negative control by DREAM complex 10777 2403 REAC:R-H…. query_1 TRUE 0.0003390 32 6279 29 0.0046186 0.9062500 REAC:R-HSA-381042 REAC PERK regulates gene expression 10777 1576 REAC:R-H…. query_1 TRUE 0.0003390 32 6279 29 0.0046186 0.9062500 REAC:R-HSA-167290 REAC Pausing and recovery of HIV elongation 10777 1629 REAC:R-H…. query_1 TRUE 0.0003390 32 6279 29 0.0046186 0.9062500 REAC:R-HSA-167287 REAC HIV elongation arrest and recovery 10777 1048 REAC:R-H…. query_1 TRUE 0.0003411 36 6279 32 0.0050964 0.8888889 REAC:R-HSA-8939243 REAC RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 10777 1823 REAC:R-H…. query_1 TRUE 0.0003411 36 6279 32 0.0050964 0.8888889 REAC:R-HSA-168638 REAC NOD1/2 Signaling Pathway 10777 1444 REAC:R-H…. query_1 TRUE 0.0003534 112 6279 85 0.0135372 0.7589286 REAC:R-HSA-187037 REAC Signaling by NTRK1 (TRKA) 10777 2159 REAC:R-H…. query_1 TRUE 0.0003618 23 6279 22 0.0035037 0.9565217 REAC:R-HSA-73980 REAC RNA Polymerase III Transcription Termination 10777 1811 REAC:R-H…. query_1 TRUE 0.0003618 23 6279 22 0.0035037 0.9565217 REAC:R-HSA-9013422 REAC RHOBTB1 GTPase cycle 10777 1770 REAC:R-H…. query_1 TRUE 0.0003618 23 6279 22 0.0035037 0.9565217 REAC:R-HSA-9013418 REAC RHOBTB2 GTPase cycle 10777 1771 REAC:R-H…. query_1 TRUE 0.0003918 90 6279 70 0.0111483 0.7777778 REAC:R-HSA-1236974 REAC ER-Phagosome pathway 10777 786 REAC:R-H…. query_1 TRUE 0.0004738 27 6279 25 0.0039815 0.9259259 REAC:R-HSA-2173795 REAC Downregulation of SMAD2/3:SMAD4 transcriptional activity 10777 749 REAC:R-H…. query_1 TRUE 0.0004738 27 6279 25 0.0039815 0.9259259 REAC:R-HSA-5693554 REAC Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 10777 1961 REAC:R-H…. query_1 TRUE 0.0004798 39 6279 34 0.0054149 0.8717949 REAC:R-HSA-8853884 REAC Transcriptional Regulation by VENTX 10777 2414 REAC:R-H…. query_1 TRUE 0.0005137 35 6279 31 0.0049371 0.8857143 REAC:R-HSA-5693537 REAC Resolution of D-Loop Structures 10777 1959 REAC:R-H…. query_1 TRUE 0.0005149 60 6279 49 0.0078038 0.8166667 REAC:R-HSA-9033241 REAC Peroxisomal protein import 10777 1638 REAC:R-H…. query_1 TRUE 0.0005164 17 6279 17 0.0027074 1.0000000 REAC:R-HSA-450604 REAC KSRP (KHSRP) binds and destabilizes mRNA 10777 1222 REAC:R-H…. query_1 TRUE 0.0005164 17 6279 17 0.0027074 1.0000000 REAC:R-HSA-450513 REAC Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 10777 2471 REAC:R-H…. query_1 TRUE 0.0005164 17 6279 17 0.0027074 1.0000000 REAC:R-HSA-5655862 REAC Translesion synthesis by POLK 10777 2438 REAC:R-H…. query_1 TRUE 0.0005164 17 6279 17 0.0027074 1.0000000 REAC:R-HSA-5656121 REAC Translesion synthesis by POLI 10777 2437 REAC:R-H…. query_1 TRUE 0.0005164 17 6279 17 0.0027074 1.0000000 REAC:R-HSA-196299 REAC Beta-catenin phosphorylation cascade 10777 208 REAC:R-H…. query_1 TRUE 0.0005164 17 6279 17 0.0027074 1.0000000 REAC:R-HSA-450385 REAC Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 10777 247 REAC:R-H…. query_1 TRUE 0.0005164 17 6279 17 0.0027074 1.0000000 REAC:R-HSA-174437 REAC Removal of the Flap Intermediate from the C-strand 10777 1943 REAC:R-H…. query_1 TRUE 0.0005268 192 6279 137 0.0218188 0.7135417 REAC:R-HSA-913531 REAC Interferon Signaling 10777 1167 REAC:R-H…. query_1 TRUE 0.0005355 46 6279 39 0.0062112 0.8478261 REAC:R-HSA-1227986 REAC Signaling by ERBB2 10777 2109 REAC:R-H…. query_1 TRUE 0.0005366 143 6279 105 0.0167224 0.7342657 REAC:R-HSA-3858494 REAC Beta-catenin independent WNT signaling 10777 207 REAC:R-H…. query_1 TRUE 0.0005377 53 6279 44 0.0070075 0.8301887 REAC:R-HSA-2151201 REAC Transcriptional activation of mitochondrial biogenesis 10777 2415 REAC:R-H…. query_1 TRUE 0.0005716 22 6279 21 0.0033445 0.9545455 REAC:R-HSA-113510 REAC E2F mediated regulation of DNA replication 10777 771 REAC:R-H…. query_1 TRUE 0.0005716 22 6279 21 0.0033445 0.9545455 REAC:R-HSA-198753 REAC ERK/MAPK targets 10777 790 REAC:R-H…. query_1 TRUE 0.0006168 42 6279 36 0.0057334 0.8571429 REAC:R-HSA-75893 REAC TNF signaling 10777 2311 REAC:R-H…. query_1 TRUE 0.0006477 49 6279 41 0.0065297 0.8367347 REAC:R-HSA-1236978 REAC Cross-presentation of soluble exogenous antigens (endosomes) 10777 395 REAC:R-H…. query_1 TRUE 0.0007171 94 6279 72 0.0114668 0.7659574 REAC:R-HSA-4420097 REAC VEGFA-VEGFR2 Pathway 10777 2496 REAC:R-H…. query_1 TRUE 0.0007247 26 6279 24 0.0038223 0.9230769 REAC:R-HSA-191273 REAC Cholesterol biosynthesis 10777 334 REAC:R-H…. query_1 TRUE 0.0007548 34 6279 30 0.0047778 0.8823529 REAC:R-HSA-4791275 REAC Signaling by WNT in cancer 10777 2189 REAC:R-H…. query_1 TRUE 0.0007702 30 6279 27 0.0043000 0.9000000 REAC:R-HSA-168274 REAC Export of Viral Ribonucleoproteins from Nucleus 10777 839 REAC:R-H…. query_1 TRUE 0.0007702 30 6279 27 0.0043000 0.9000000 REAC:R-HSA-167243 REAC Tat-mediated HIV elongation arrest and recovery 10777 2349 REAC:R-H…. query_1 TRUE 0.0007702 30 6279 27 0.0043000 0.9000000 REAC:R-HSA-167238 REAC Pausing and recovery of Tat-mediated HIV elongation 10777 1630 REAC:R-H…. query_1 TRUE 0.0008035 78 6279 61 0.0097149 0.7820513 REAC:R-HSA-5619084 REAC ABC transporter disorders 10777 4 REAC:R-H…. query_1 TRUE 0.0008499 16 6279 16 0.0025482 1.0000000 REAC:R-HSA-1660516 REAC Synthesis of PIPs at the early endosome membrane 10777 2263 REAC:R-H…. query_1 TRUE 0.0008499 16 6279 16 0.0025482 1.0000000 REAC:R-HSA-429958 REAC mRNA decay by 3’ to 5’ exoribonuclease 10777 2568 REAC:R-H…. query_1 TRUE 0.0008499 16 6279 16 0.0025482 1.0000000 REAC:R-HSA-5684264 REAC MAP3K8 (TPL2)-dependent MAPK1/3 activation 10777 1281 REAC:R-H…. query_1 TRUE 0.0008499 16 6279 16 0.0025482 1.0000000 REAC:R-HSA-110312 REAC Translesion synthesis by REV1 10777 2439 REAC:R-H…. query_1 TRUE 0.0008499 16 6279 16 0.0025482 1.0000000 REAC:R-HSA-2995383 REAC Initiation of Nuclear Envelope (NE) Reformation 10777 1141 REAC:R-H…. query_1 TRUE 0.0008596 55 6279 45 0.0071667 0.8181818 REAC:R-HSA-9639288 REAC Amino acids regulate mTORC1 10777 136 REAC:R-H…. query_1 TRUE 0.0009032 21 6279 20 0.0031852 0.9523810 REAC:R-HSA-70895 REAC Branched-chain amino acid catabolism 10777 243 REAC:R-H…. query_1 TRUE 0.0009032 21 6279 20 0.0031852 0.9523810 REAC:R-HSA-6804115 REAC TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 10777 2326 REAC:R-H…. query_1 TRUE 0.0009032 21 6279 20 0.0031852 0.9523810 REAC:R-HSA-141430 REAC Inactivation of APC/C via direct inhibition of the APC/C complex 10777 1116 REAC:R-H…. query_1 TRUE 0.0009032 21 6279 20 0.0031852 0.9523810 REAC:R-HSA-141405 REAC Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 10777 1139 REAC:R-H…. query_1 TRUE 0.0009515 102 6279 77 0.0122631 0.7549020 REAC:R-HSA-6807878 REAC COPI-mediated anterograde transport 10777 267 REAC:R-H…. query_1 TRUE 0.0010541 51 6279 42 0.0066890 0.8235294 REAC:R-HSA-8848021 REAC Signaling by PTK6 10777 2170 REAC:R-H…. query_1 TRUE 0.0010541 51 6279 42 0.0066890 0.8235294 REAC:R-HSA-9006927 REAC Signaling by Non-Receptor Tyrosine Kinases 10777 2163 REAC:R-H…. query_1 TRUE 0.0011020 80 6279 62 0.0098742 0.7750000 REAC:R-HSA-9663891 REAC Selective autophagy 10777 2063 REAC:R-H…. query_1 TRUE 0.0011074 25 6279 23 0.0036630 0.9200000 REAC:R-HSA-69273 REAC Cyclin A/B1/B2 associated events during G2/M transition 10777 397 REAC:R-H…. query_1 TRUE 0.0011639 86 6279 66 0.0105112 0.7674419 REAC:R-HSA-428157 REAC Sphingolipid metabolism 10777 2219 REAC:R-H…. query_1 TRUE 0.0012252 476 6279 314 0.0500080 0.6596639 REAC:R-HSA-6798695 REAC Neutrophil degranulation 10777 1511 REAC:R-H…. query_1 TRUE 0.0012252 98 6279 74 0.0117853 0.7551020 REAC:R-HSA-202424 REAC Downstream TCR signaling 10777 751 REAC:R-H…. query_1 TRUE 0.0012279 104 6279 78 0.0124224 0.7500000 REAC:R-HSA-194138 REAC Signaling by VEGF 10777 2187 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-5609975 REAC Diseases associated with glycosylation precursor biosynthesis 10777 714 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-430039 REAC mRNA decay by 5’ to 3’ exoribonuclease 10777 2569 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-5339716 REAC Signaling by GSK3beta mutants 10777 2134 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-9694631 REAC Maturation of nucleoprotein 10777 1323 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-156711 REAC Polo-like kinase mediated events 10777 1678 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-5358508 REAC Mismatch Repair 10777 1381 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-4839743 REAC Signaling by CTNNB1 phospho-site mutants 10777 2105 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-1362300 REAC Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 10777 2404 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-5358752 REAC CTNNB1 T41 mutants aren’t phosphorylated 10777 281 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-5358751 REAC CTNNB1 S45 mutants aren’t phosphorylated 10777 280 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-5358749 REAC CTNNB1 S37 mutants aren’t phosphorylated 10777 279 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-5358747 REAC CTNNB1 S33 mutants aren’t phosphorylated 10777 278 REAC:R-H…. query_1 TRUE 0.0013816 15 6279 15 0.0023889 1.0000000 REAC:R-HSA-69183 REAC Processive synthesis on the lagging strand 10777 1712 REAC:R-H…. query_1 TRUE 0.0014121 20 6279 19 0.0030260 0.9500000 REAC:R-HSA-176407 REAC Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 10777 387 REAC:R-H…. query_1 TRUE 0.0014121 20 6279 19 0.0030260 0.9500000 REAC:R-HSA-416572 REAC Sema4D induced cell migration and growth-cone collapse 10777 2068 REAC:R-H…. query_1 TRUE 0.0014932 85 6279 65 0.0103520 0.7647059 REAC:R-HSA-5632684 REAC Hedgehog ‘on’ state 10777 1055 REAC:R-H…. query_1 TRUE 0.0016866 24 6279 22 0.0035037 0.9166667 REAC:R-HSA-400685 REAC Sema4D in semaphorin signaling 10777 2067 REAC:R-H…. query_1 TRUE 0.0017154 28 6279 25 0.0039815 0.8928571 REAC:R-HSA-5619107 REAC Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 10777 663 REAC:R-H…. query_1 TRUE 0.0017154 28 6279 25 0.0039815 0.8928571 REAC:R-HSA-170822 REAC Regulation of Glucokinase by Glucokinase Regulatory Protein 10777 1876 REAC:R-H…. query_1 TRUE 0.0017730 72 6279 56 0.0089186 0.7777778 REAC:R-HSA-1445148 REAC Translocation of SLC2A4 (GLUT4) to the plasma membrane 10777 2441 REAC:R-H…. query_1 TRUE 0.0018069 39 6279 33 0.0052556 0.8461538 REAC:R-HSA-9013420 REAC RHOU GTPase cycle 10777 1782 REAC:R-H…. query_1 TRUE 0.0019724 105 6279 78 0.0124224 0.7428571 REAC:R-HSA-1236975 REAC Antigen processing-Cross presentation 10777 147 REAC:R-H…. query_1 TRUE 0.0019975 99 6279 74 0.0117853 0.7474747 REAC:R-HSA-6811434 REAC COPI-dependent Golgi-to-ER retrograde traffic 10777 265 REAC:R-H…. query_1 TRUE 0.0021027 131 6279 95 0.0151298 0.7251908 REAC:R-HSA-166520 REAC Signaling by NTRKs 10777 2162 REAC:R-H…. query_1 TRUE 0.0022439 19 6279 18 0.0028667 0.9473684 REAC:R-HSA-77595 REAC Processing of Intronless Pre-mRNAs 10777 1709 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-198323 REAC AKT phosphorylates targets in the cytosol 10777 11 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-5467337 REAC APC truncation mutants have impaired AXIN binding 10777 19 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-1295596 REAC Spry regulation of FGF signaling 10777 2220 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-4839735 REAC Signaling by AXIN mutants 10777 2099 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-4839748 REAC Signaling by AMER1 mutants 10777 2097 REAC:R-H…. query_1 TRUE 0.0022439 52 6279 42 0.0066890 0.8076923 REAC:R-HSA-1660499 REAC Synthesis of PIPs at the plasma membrane 10777 2265 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-4839744 REAC Signaling by APC mutants 10777 2098 REAC:R-H…. query_1 TRUE 0.0022439 19 6279 18 0.0028667 0.9473684 REAC:R-HSA-110320 REAC Translesion Synthesis by POLH 10777 2436 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-69166 REAC Removal of the Flap Intermediate 10777 1942 REAC:R-H…. query_1 TRUE 0.0022439 19 6279 18 0.0028667 0.9473684 REAC:R-HSA-168927 REAC TICAM1, RIP1-mediated IKK complex recruitment 10777 2305 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-5358565 REAC Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 10777 1383 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-5358606 REAC Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 10777 1382 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-5467340 REAC AXIN missense mutants destabilize the destruction complex 10777 38 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-69109 REAC Leading Strand Synthesis 10777 1246 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-5467348 REAC Truncations of AMER1 destabilize the destruction complex 10777 2472 REAC:R-H…. query_1 TRUE 0.0022439 14 6279 14 0.0022297 1.0000000 REAC:R-HSA-69091 REAC Polymerase switching 10777 1679 REAC:R-H…. query_1 TRUE 0.0022439 19 6279 18 0.0028667 0.9473684 REAC:R-HSA-111471 REAC Apoptotic factor-mediated response 10777 157 REAC:R-H…. query_1 TRUE 0.0023217 31 6279 27 0.0043000 0.8709677 REAC:R-HSA-73863 REAC RNA Polymerase I Transcription Termination 10777 1794 REAC:R-H…. query_1 TRUE 0.0023217 31 6279 27 0.0043000 0.8709677 REAC:R-HSA-4641262 REAC Disassembly of the destruction complex and recruitment of AXIN to the membrane 10777 709 REAC:R-H…. query_1 TRUE 0.0023720 55 6279 44 0.0070075 0.8000000 REAC:R-HSA-168643 REAC Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 10777 1542 REAC:R-H…. query_1 TRUE 0.0024799 83 6279 63 0.0100334 0.7590361 REAC:R-HSA-1483255 REAC PI Metabolism 10777 1577 REAC:R-H…. query_1 TRUE 0.0025021 27 6279 24 0.0038223 0.8888889 REAC:R-HSA-380994 REAC ATF4 activates genes in response to endoplasmic reticulum stress 10777 32 REAC:R-H…. query_1 TRUE 0.0025021 27 6279 24 0.0038223 0.8888889 REAC:R-HSA-1368108 REAC BMAL1:CLOCK,NPAS2 activates circadian gene expression 10777 195 REAC:R-H…. query_1 TRUE 0.0025021 27 6279 24 0.0038223 0.8888889 REAC:R-HSA-5205647 REAC Mitophagy 10777 1398 REAC:R-H…. query_1 TRUE 0.0025032 23 6279 21 0.0033445 0.9130435 REAC:R-HSA-450302 REAC activated TAK1 mediates p38 MAPK activation 10777 2544 REAC:R-H…. query_1 TRUE 0.0025032 23 6279 21 0.0033445 0.9130435 REAC:R-HSA-9637690 REAC Response of Mtb to phagocytosis 10777 1967 REAC:R-H…. query_1 TRUE 0.0025870 127 6279 92 0.0146520 0.7244094 REAC:R-HSA-163200 REAC Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 10777 1964 REAC:R-H…. query_1 TRUE 0.0027055 48 6279 39 0.0062112 0.8125000 REAC:R-HSA-177929 REAC Signaling by EGFR 10777 2106 REAC:R-H…. query_1 TRUE 0.0027196 121 6279 88 0.0140150 0.7272727 REAC:R-HSA-196849 REAC Metabolism of water-soluble vitamins and cofactors 10777 1365 REAC:R-H…. query_1 TRUE 0.0029565 34 6279 29 0.0046186 0.8529412 REAC:R-HSA-9772572 REAC Early SARS-CoV-2 Infection Events 10777 794 REAC:R-H…. query_1 TRUE 0.0029565 34 6279 29 0.0046186 0.8529412 REAC:R-HSA-9615710 REAC Late endosomal microautophagy 10777 1244 REAC:R-H…. query_1 TRUE 0.0029699 51 6279 41 0.0065297 0.8039216 REAC:R-HSA-5620920 REAC Cargo trafficking to the periciliary membrane 10777 298 REAC:R-H…. query_1 TRUE 0.0030636 103 6279 76 0.0121038 0.7378641 REAC:R-HSA-382556 REAC ABC-family proteins mediated transport 10777 6 REAC:R-H…. query_1 TRUE 0.0031289 76 6279 58 0.0092371 0.7631579 REAC:R-HSA-204998 REAC Cell death signalling via NRAGE, NRIF and NADE 10777 311 REAC:R-H…. query_1 TRUE 0.0031892 82 6279 62 0.0098742 0.7560976 REAC:R-HSA-6802957 REAC Oncogenic MAPK signaling 10777 1553 REAC:R-H…. query_1 TRUE 0.0031950 85 6279 64 0.0101927 0.7529412 REAC:R-HSA-9679191 REAC Potential therapeutics for SARS 10777 1692 REAC:R-H…. query_1 TRUE 0.0032956 123 6279 89 0.0141742 0.7235772 REAC:R-HSA-2132295 REAC MHC class II antigen presentation 10777 1304 REAC:R-H…. query_1 TRUE 0.0033826 30 6279 26 0.0041408 0.8666667 REAC:R-HSA-5357956 REAC TNFR1-induced NFkappaB signaling pathway 10777 2312 REAC:R-H…. query_1 TRUE 0.0034380 18 6279 17 0.0027074 0.9444444 REAC:R-HSA-1368082 REAC RORA activates gene expression 10777 1817 REAC:R-H…. query_1 TRUE 0.0034380 18 6279 17 0.0027074 0.9444444 REAC:R-HSA-8851708 REAC Signaling by FGFR2 IIIa TM 10777 2122 REAC:R-H…. query_1 TRUE 0.0035524 37 6279 31 0.0049371 0.8378378 REAC:R-HSA-77289 REAC Mitochondrial Fatty Acid Beta-Oxidation 10777 1385 REAC:R-H…. query_1 TRUE 0.0035524 37 6279 31 0.0049371 0.8378378 REAC:R-HSA-9013407 REAC RHOH GTPase cycle 10777 1777 REAC:R-H…. query_1 TRUE 0.0036486 13 6279 13 0.0020704 1.0000000 REAC:R-HSA-111461 REAC Cytochrome c-mediated apoptotic response 10777 403 REAC:R-H…. query_1 TRUE 0.0036486 13 6279 13 0.0020704 1.0000000 REAC:R-HSA-933543 REAC NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 10777 1434 REAC:R-H…. query_1 TRUE 0.0036486 13 6279 13 0.0020704 1.0000000 REAC:R-HSA-162658 REAC Golgi Cisternae Pericentriolar Stack Reorganization 10777 1026 REAC:R-H…. query_1 TRUE 0.0036486 13 6279 13 0.0020704 1.0000000 REAC:R-HSA-202670 REAC ERKs are inactivated 10777 791 REAC:R-H…. query_1 TRUE 0.0036486 13 6279 13 0.0020704 1.0000000 REAC:R-HSA-75035 REAC Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 10777 333 REAC:R-H…. query_1 TRUE 0.0036594 47 6279 38 0.0060519 0.8085106 REAC:R-HSA-9707616 REAC Heme signaling 10777 1059 REAC:R-H…. query_1 TRUE 0.0036594 26 6279 23 0.0036630 0.8846154 REAC:R-HSA-5674400 REAC Constitutive Signaling by AKT1 E17K in Cancer 10777 378 REAC:R-H…. query_1 TRUE 0.0036594 26 6279 23 0.0036630 0.8846154 REAC:R-HSA-186763 REAC Downstream signal transduction 10777 752 REAC:R-H…. query_1 TRUE 0.0036594 26 6279 23 0.0036630 0.8846154 REAC:R-HSA-901042 REAC Calnexin/calreticulin cycle 10777 291 REAC:R-H…. query_1 TRUE 0.0036594 26 6279 23 0.0036630 0.8846154 REAC:R-HSA-174411 REAC Polymerase switching on the C-strand of the telomere 10777 1680 REAC:R-H…. query_1 TRUE 0.0037559 22 6279 20 0.0031852 0.9090909 REAC:R-HSA-937041 REAC IKK complex recruitment mediated by RIP1 10777 1085 REAC:R-H…. query_1 TRUE 0.0037559 22 6279 20 0.0031852 0.9090909 REAC:R-HSA-5205685 REAC PINK1-PRKN Mediated Mitophagy 10777 1590 REAC:R-H…. query_1 TRUE 0.0038813 319 6279 213 0.0339226 0.6677116 REAC:R-HSA-195258 REAC RHO GTPase Effectors 10777 1754 REAC:R-H…. query_1 TRUE 0.0041742 33 6279 28 0.0044593 0.8484848 REAC:R-HSA-5357905 REAC Regulation of TNFR1 signaling 10777 1900 REAC:R-H…. query_1 TRUE 0.0041742 33 6279 28 0.0044593 0.8484848 REAC:R-HSA-5673000 REAC RAF activation 10777 1747 REAC:R-H…. query_1 TRUE 0.0043961 186 6279 129 0.0205447 0.6935484 REAC:R-HSA-196854 REAC Metabolism of vitamins and cofactors 10777 1364 REAC:R-H…. query_1 TRUE 0.0049389 210 6279 144 0.0229336 0.6857143 REAC:R-HSA-1483257 REAC Phospholipid metabolism 10777 1658 REAC:R-H…. query_1 TRUE 0.0049955 36 6279 30 0.0047778 0.8333333 REAC:R-HSA-9029569 REAC NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 10777 1462 REAC:R-H…. query_1 TRUE 0.0049955 36 6279 30 0.0047778 0.8333333 REAC:R-HSA-6804757 REAC Regulation of TP53 Degradation 10777 1906 REAC:R-H…. query_1 TRUE 0.0053601 17 6279 16 0.0025482 0.9411765 REAC:R-HSA-1810476 REAC RIP-mediated NFkB activation via ZBP1 10777 1784 REAC:R-H…. query_1 TRUE 0.0053601 17 6279 16 0.0025482 0.9411765 REAC:R-HSA-8934593 REAC Regulation of RUNX1 Expression and Activity 10777 1896 REAC:R-H…. query_1 TRUE 0.0053601 17 6279 16 0.0025482 0.9411765 REAC:R-HSA-9661069 REAC Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) 10777 666 REAC:R-H…. query_1 TRUE 0.0053601 17 6279 16 0.0025482 0.9411765 REAC:R-HSA-9659787 REAC Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects 10777 43 REAC:R-H…. query_1 TRUE 0.0054712 25 6279 22 0.0035037 0.8800000 REAC:R-HSA-933542 REAC TRAF6 mediated NF-kB activation 10777 2332 REAC:R-H…. query_1 TRUE 0.0057143 39 6279 32 0.0050964 0.8205128 REAC:R-HSA-6783310 REAC Fanconi Anemia Pathway 10777 886 REAC:R-H…. query_1 TRUE 0.0057337 21 6279 19 0.0030260 0.9047619 REAC:R-HSA-1606322 REAC ZBP1(DAI) mediated induction of type I IFNs 10777 2540 REAC:R-H…. query_1 TRUE 0.0057337 21 6279 19 0.0030260 0.9047619 REAC:R-HSA-8862803 REAC Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models 10777 699 REAC:R-H…. query_1 TRUE 0.0057337 21 6279 19 0.0030260 0.9047619 REAC:R-HSA-912631 REAC Regulation of signaling by CBL 10777 1933 REAC:R-H…. query_1 TRUE 0.0057337 21 6279 19 0.0030260 0.9047619 REAC:R-HSA-8863678 REAC Neurodegenerative Diseases 10777 1502 REAC:R-H…. query_1 TRUE 0.0059592 12 6279 12 0.0019111 1.0000000 REAC:R-HSA-5685939 REAC HDR through MMEJ (alt-NHEJ) 10777 1041 REAC:R-H…. query_1 TRUE 0.0059592 12 6279 12 0.0019111 1.0000000 REAC:R-HSA-3371511 REAC HSF1 activation 10777 1051 REAC:R-H…. query_1 TRUE 0.0059592 12 6279 12 0.0019111 1.0000000 REAC:R-HSA-176974 REAC Unwinding of DNA 10777 2487 REAC:R-H…. query_1 TRUE 0.0059592 12 6279 12 0.0019111 1.0000000 REAC:R-HSA-9755779 REAC SARS-CoV-2 targets host intracellular signalling and regulatory pathways 10777 2005 REAC:R-H…. query_1 TRUE 0.0059592 32 6279 27 0.0043000 0.8437500 REAC:R-HSA-445989 REAC TAK1-dependent IKK and NF-kappa-B activation 10777 2287 REAC:R-H…. query_1 TRUE 0.0062924 42 6279 34 0.0054149 0.8095238 REAC:R-HSA-3769402 REAC Deactivation of the beta-catenin transactivating complex 10777 431 REAC:R-H…. query_1 TRUE 0.0063167 91 6279 67 0.0106705 0.7362637 REAC:R-HSA-390466 REAC Chaperonin-mediated protein folding 10777 331 REAC:R-H…. query_1 TRUE 0.0065845 82 6279 61 0.0097149 0.7439024 REAC:R-HSA-168928 REAC DDX58/IFIH1-mediated induction of interferon-alpha/beta 10777 415 REAC:R-H…. query_1 TRUE 0.0070612 28 6279 24 0.0038223 0.8571429 REAC:R-HSA-389957 REAC Prefoldin mediated transfer of substrate to CCT/TriC 10777 1698 REAC:R-H…. query_1 TRUE 0.0073279 48 6279 38 0.0060519 0.7916667 REAC:R-HSA-9012852 REAC Signaling by NOTCH3 10777 2157 REAC:R-H…. query_1 TRUE 0.0073787 221 6279 150 0.0238892 0.6787330 REAC:R-HSA-5689880 REAC Ub-specific processing proteases 10777 2479 REAC:R-H…. query_1 TRUE 0.0080305 90 6279 66 0.0105112 0.7333333 REAC:R-HSA-2682334 REAC EPH-Ephrin signaling 10777 780 REAC:R-H…. query_1 TRUE 0.0080930 24 6279 21 0.0033445 0.8750000 REAC:R-HSA-9734009 REAC Defective Intrinsic Pathway for Apoptosis 10777 551 REAC:R-H…. query_1 TRUE 0.0083889 16 6279 15 0.0023889 0.9375000 REAC:R-HSA-175474 REAC Assembly Of The HIV Virion 10777 166 REAC:R-H…. query_1 TRUE 0.0083889 16 6279 15 0.0023889 0.9375000 REAC:R-HSA-8866427 REAC VLDLR internalisation and degradation 10777 2501 REAC:R-H…. query_1 TRUE 0.0083889 16 6279 15 0.0023889 0.9375000 REAC:R-HSA-204174 REAC Regulation of pyruvate dehydrogenase (PDH) complex 10777 1932 REAC:R-H…. query_1 TRUE 0.0084709 308 6279 204 0.0324892 0.6623377 REAC:R-HSA-5683057 REAC MAPK family signaling cascades 10777 1282 REAC:R-H…. query_1 TRUE 0.0084938 78 6279 58 0.0092371 0.7435897 REAC:R-HSA-446193 REAC Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 10777 239 REAC:R-H…. query_1 TRUE 0.0085130 31 6279 26 0.0041408 0.8387097 REAC:R-HSA-187687 REAC Signalling to ERKs 10777 2205 REAC:R-H…. query_1 TRUE 0.0085440 138 6279 97 0.0154483 0.7028986 REAC:R-HSA-5693538 REAC Homology Directed Repair 10777 1071 REAC:R-H…. query_1 TRUE 0.0086664 20 6279 18 0.0028667 0.9000000 REAC:R-HSA-3781860 REAC Diseases associated with N-glycosylation of proteins 10777 711 REAC:R-H…. query_1 TRUE 0.0093076 98 6279 71 0.0113075 0.7244898 REAC:R-HSA-391251 REAC Protein folding 10777 1721 REAC:R-H…. query_1 TRUE 0.0098036 11 6279 11 0.0017519 1.0000000 REAC:R-HSA-9708530 REAC Regulation of BACH1 activity 10777 1872 REAC:R-H…. query_1 TRUE 0.0098036 11 6279 11 0.0017519 1.0000000 REAC:R-HSA-9627069 REAC Regulation of the apoptosome activity 10777 1935 REAC:R-H…. query_1 TRUE 0.0098036 11 6279 11 0.0017519 1.0000000 REAC:R-HSA-9683610 REAC Maturation of nucleoprotein 10777 1322 REAC:R-H…. query_1 TRUE 0.0098036 11 6279 11 0.0017519 1.0000000 REAC:R-HSA-196780 REAC Biotin transport and metabolism 10777 240 REAC:R-H…. query_1 TRUE 0.0098036 11 6279 11 0.0017519 1.0000000 REAC:R-HSA-4755510 REAC SUMOylation of immune response proteins 10777 2051 REAC:R-H…. query_1 TRUE 0.0098036 11 6279 11 0.0017519 1.0000000 REAC:R-HSA-9664873 REAC Pexophagy 10777 1640 REAC:R-H…. query_1 TRUE 0.0098036 11 6279 11 0.0017519 1.0000000 REAC:R-HSA-9014325 REAC TICAM1,TRAF6-dependent induction of TAK1 complex 10777 2306 REAC:R-H…. query_1 TRUE 0.0098036 11 6279 11 0.0017519 1.0000000 REAC:R-HSA-9645460 REAC Alpha-protein kinase 1 signaling pathway 10777 129 REAC:R-H…. query_1 TRUE 0.0098036 11 6279 11 0.0017519 1.0000000 REAC:R-HSA-111458 REAC Formation of apoptosome 10777 908 REAC:R-H…. query_1 TRUE 0.0101141 27 6279 23 0.0036630 0.8518519 REAC:R-HSA-9635486 REAC Infection with Mycobacterium tuberculosis 10777 1122 REAC:R-H…. query_1 TRUE 0.0107463 120 6279 85 0.0135372 0.7083333 REAC:R-HSA-202403 REAC TCR signaling 10777 2292 REAC:R-H…. query_1 TRUE 0.0108526 37 6279 30 0.0047778 0.8108108 REAC:R-HSA-6806003 REAC Regulation of TP53 Expression and Degradation 10777 1908 REAC:R-H…. query_1 TRUE 0.0118460 23 6279 20 0.0031852 0.8695652 REAC:R-HSA-171319 REAC Telomere Extension By Telomerase 10777 2353 REAC:R-H…. query_1 TRUE 0.0120296 30 6279 25 0.0039815 0.8333333 REAC:R-HSA-9022692 REAC Regulation of MECP2 expression and activity 10777 1883 REAC:R-H…. query_1 TRUE 0.0120296 30 6279 25 0.0039815 0.8333333 REAC:R-HSA-9674555 REAC Signaling by CSF3 (G-CSF) 10777 2104 REAC:R-H…. query_1 TRUE 0.0120296 30 6279 25 0.0039815 0.8333333 REAC:R-HSA-70268 REAC Pyruvate metabolism 10777 1739 REAC:R-H…. query_1 TRUE 0.0125576 43 6279 34 0.0054149 0.7906977 REAC:R-HSA-1660661 REAC Sphingolipid de novo biosynthesis 10777 2218 REAC:R-H…. query_1 TRUE 0.0129111 19 6279 17 0.0027074 0.8947368 REAC:R-HSA-6804760 REAC Regulation of TP53 Activity through Methylation 10777 1904 REAC:R-H…. query_1 TRUE 0.0129111 15 6279 14 0.0022297 0.9333333 REAC:R-HSA-2173791 REAC TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 10777 2299 REAC:R-H…. query_1 TRUE 0.0129111 19 6279 17 0.0027074 0.8947368 REAC:R-HSA-8978934 REAC Metabolism of cofactors 10777 1347 REAC:R-H…. query_1 TRUE 0.0129111 15 6279 14 0.0022297 0.9333333 REAC:R-HSA-937072 REAC TRAF6-mediated induction of TAK1 complex within TLR4 complex 10777 2334 REAC:R-H…. query_1 TRUE 0.0129111 15 6279 14 0.0022297 0.9333333 REAC:R-HSA-975163 REAC IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 10777 1097 REAC:R-H…. query_1 TRUE 0.0129111 19 6279 17 0.0027074 0.8947368 REAC:R-HSA-5627117 REAC RHO GTPases Activate ROCKs 10777 1758 REAC:R-H…. query_1 TRUE 0.0129111 15 6279 14 0.0022297 0.9333333 REAC:R-HSA-4655427 REAC SUMOylation of DNA methylation proteins 10777 2046 REAC:R-H…. query_1 TRUE 0.0129111 15 6279 14 0.0022297 0.9333333 REAC:R-HSA-9648895 REAC Response of EIF2AK1 (HRI) to heme deficiency 10777 1965 REAC:R-H…. query_1 TRUE 0.0129111 19 6279 17 0.0027074 0.8947368 REAC:R-HSA-9603798 REAC Class I peroxisomal membrane protein import 10777 354 REAC:R-H…. query_1 TRUE 0.0129111 15 6279 14 0.0022297 0.9333333 REAC:R-HSA-111447 REAC Activation of BAD and translocation to mitochondria 10777 72 REAC:R-H…. query_1 TRUE 0.0141489 64 6279 48 0.0076445 0.7500000 REAC:R-HSA-6802952 REAC Signaling by BRAF and RAF1 fusions 10777 2102 REAC:R-H…. query_1 TRUE 0.0141489 64 6279 48 0.0076445 0.7500000 REAC:R-HSA-5654738 REAC Signaling by FGFR2 10777 2121 REAC:R-H…. query_1 TRUE 0.0141606 61 6279 46 0.0073260 0.7540984 REAC:R-HSA-198725 REAC Nuclear Events (kinase and transcription factor activation) 10777 1528 REAC:R-H…. query_1 TRUE 0.0157377 104 6279 74 0.0117853 0.7115385 REAC:R-HSA-8856825 REAC Cargo recognition for clathrin-mediated endocytosis 10777 297 REAC:R-H…. query_1 TRUE 0.0161809 10 6279 10 0.0015926 1.0000000 REAC:R-HSA-390450 REAC Folding of actin by CCT/TriC 10777 897 REAC:R-H…. query_1 TRUE 0.0161809 10 6279 10 0.0015926 1.0000000 REAC:R-HSA-937042 REAC IRAK2 mediated activation of TAK1 complex 10777 1096 REAC:R-H…. query_1 TRUE 0.0161809 10 6279 10 0.0015926 1.0000000 REAC:R-HSA-9617629 REAC Regulation of FOXO transcriptional activity by acetylation 10777 1874 REAC:R-H…. query_1 TRUE 0.0172416 22 6279 19 0.0030260 0.8636364 REAC:R-HSA-3296482 REAC Defects in vitamin and cofactor metabolism 10777 682 REAC:R-H…. query_1 TRUE 0.0172416 22 6279 19 0.0030260 0.8636364 REAC:R-HSA-450321 REAC JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 10777 1218 REAC:R-H…. query_1 TRUE 0.0174429 45 6279 35 0.0055741 0.7777778 REAC:R-HSA-9024446 REAC NR1H2 and NR1H3-mediated signaling 10777 1461 REAC:R-H…. query_1 TRUE 0.0183415 120 6279 84 0.0133779 0.7000000 REAC:R-HSA-9705671 REAC SARS-CoV-2 activates/modulates innate and adaptive immune responses 10777 2001 REAC:R-H…. query_1 TRUE 0.0184187 57 6279 43 0.0068482 0.7543860 REAC:R-HSA-917937 REAC Iron uptake and transport 10777 1217 REAC:R-H…. query_1 TRUE 0.0186801 188 6279 127 0.0202262 0.6755319 REAC:R-HSA-69306 REAC DNA Replication 10777 424 REAC:0000000 query_1 TRUE 0.0195602 18 6279 16 0.0025482 0.8888889 REAC:R-HSA-9725371 REAC Nuclear events stimulated by ALK signaling in cancer 10777 1532 REAC:R-H…. query_1 TRUE 0.0195602 18 6279 16 0.0025482 0.8888889 REAC:R-HSA-3232118 REAC SUMOylation of transcription factors 10777 2055 REAC:R-H…. query_1 TRUE 0.0201316 14 6279 13 0.0020704 0.9285714 REAC:R-HSA-174495 REAC Synthesis And Processing Of GAG, GAGPOL Polyproteins 10777 2237 REAC:R-H…. query_1 TRUE 0.0201316 14 6279 13 0.0020704 0.9285714 REAC:R-HSA-174490 REAC Membrane binding and targetting of GAG proteins 10777 1339 REAC:R-H…. query_1 TRUE 0.0201316 14 6279 13 0.0020704 0.9285714 REAC:R-HSA-8941856 REAC RUNX3 regulates NOTCH signaling 10777 1841 REAC:R-H…. query_1 TRUE 0.0201316 14 6279 13 0.0020704 0.9285714 REAC:R-HSA-6803205 REAC TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 10777 2327 REAC:R-H…. query_1 TRUE 0.0201316 14 6279 13 0.0020704 0.9285714 REAC:R-HSA-8956320 REAC Nucleotide biosynthesis 10777 1537 REAC:R-H…. query_1 TRUE 0.0202828 35 6279 28 0.0044593 0.8000000 REAC:R-HSA-5663213 REAC RHO GTPases Activate WASPs and WAVEs 10777 1760 REAC:R-H…. query_1 TRUE 0.0202828 35 6279 28 0.0044593 0.8000000 REAC:R-HSA-432720 REAC Lysosome Vesicle Biogenesis 10777 1276 REAC:R-H…. query_1 TRUE 0.0206187 25 6279 21 0.0033445 0.8400000 REAC:R-HSA-9013507 REAC NOTCH3 Activation and Transmission of Signal to the Nucleus 10777 1450 REAC:R-H…. query_1 TRUE 0.0206187 25 6279 21 0.0033445 0.8400000 REAC:R-HSA-9705462 REAC Inactivation of CSF3 (G-CSF) signaling 10777 1118 REAC:R-H…. query_1 TRUE 0.0206187 25 6279 21 0.0033445 0.8400000 REAC:R-HSA-429947 REAC Deadenylation of mRNA 10777 432 REAC:R-H…. query_1 TRUE 0.0224683 704 6279 442 0.0703934 0.6278409 REAC:R-HSA-1280215 REAC Cytokine Signaling in Immune system 10777 404 REAC:R-H…. query_1 TRUE 0.0236996 173 6279 117 0.0186335 0.6763006 REAC:R-HSA-8978868 REAC Fatty acid metabolism 10777 889 REAC:R-H…. query_1 TRUE 0.0237492 53 6279 40 0.0063704 0.7547170 REAC:R-HSA-6811436 REAC COPI-independent Golgi-to-ER retrograde traffic 10777 266 REAC:R-H…. query_1 TRUE 0.0250565 21 6279 18 0.0028667 0.8571429 REAC:R-HSA-379726 REAC Mitochondrial tRNA aminoacylation 10777 1391 REAC:R-H…. query_1 TRUE 0.0250565 21 6279 18 0.0028667 0.8571429 REAC:R-HSA-901032 REAC ER Quality Control Compartment (ERQC) 10777 784 REAC:R-H…. query_1 TRUE 0.0250843 132 6279 91 0.0144928 0.6893939 REAC:R-HSA-5693567 REAC HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 10777 1040 REAC:R-H…. query_1 TRUE 0.0264676 9 6279 9 0.0014333 1.0000000 REAC:R-HSA-9636383 REAC Prevention of phagosomal-lysosomal fusion 10777 1704 REAC:R-H…. query_1 TRUE 0.0264676 9 6279 9 0.0014333 1.0000000 REAC:R-HSA-8948747 REAC Regulation of PTEN localization 10777 1892 REAC:R-H…. query_1 TRUE 0.0264676 9 6279 9 0.0014333 1.0000000 REAC:R-HSA-164940 REAC Nef mediated downregulation of MHC class I complex cell surface expression 10777 1479 REAC:R-H…. query_1 TRUE 0.0264676 9 6279 9 0.0014333 1.0000000 REAC:R-HSA-113507 REAC E2F-enabled inhibition of pre-replication complex formation 10777 772 REAC:R-H…. query_1 TRUE 0.0264676 9 6279 9 0.0014333 1.0000000 REAC:R-HSA-8943723 REAC Regulation of PTEN mRNA translation 10777 1893 REAC:R-H…. query_1 TRUE 0.0264676 9 6279 9 0.0014333 1.0000000 REAC:R-HSA-8849469 REAC PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 10777 1621 REAC:R-H…. query_1 TRUE 0.0264676 9 6279 9 0.0014333 1.0000000 REAC:R-HSA-162592 REAC Integration of provirus 10777 1154 REAC:R-H…. query_1 TRUE 0.0264676 9 6279 9 0.0014333 1.0000000 REAC:R-HSA-8983711 REAC OAS antiviral response 10777 1548 REAC:R-H…. query_1 TRUE 0.0288349 64 6279 47 0.0074853 0.7343750 REAC:R-HSA-8873719 REAC RAB geranylgeranylation 10777 1743 REAC:R-H…. query_1 TRUE 0.0288769 17 6279 15 0.0023889 0.8823529 REAC:R-HSA-9670439 REAC Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants 10777 2200 REAC:R-H…. query_1 TRUE 0.0288769 17 6279 15 0.0023889 0.8823529 REAC:R-HSA-162710 REAC Synthesis of glycosylphosphatidylinositol (GPI) 10777 2279 REAC:R-H…. query_1 TRUE 0.0288769 37 6279 29 0.0046186 0.7837838 REAC:R-HSA-111465 REAC Apoptotic cleavage of cellular proteins 10777 155 REAC:R-H…. query_1 TRUE 0.0288769 17 6279 15 0.0023889 0.8823529 REAC:R-HSA-9669938 REAC Signaling by KIT in disease 10777 2139 REAC:R-H…. query_1 TRUE 0.0292621 24 6279 20 0.0031852 0.8333333 REAC:R-HSA-9634638 REAC Estrogen-dependent nuclear events downstream of ESR-membrane signaling 10777 824 REAC:R-H…. query_1 TRUE 0.0296296 40 6279 31 0.0049371 0.7750000 REAC:R-HSA-3928662 REAC EPHB-mediated forward signaling 10777 783 REAC:R-H…. query_1 TRUE 0.0296998 58 6279 43 0.0068482 0.7413793 REAC:R-HSA-8866654 REAC E3 ubiquitin ligases ubiquitinate target proteins 10777 773 REAC:R-H…. query_1 TRUE 0.0307338 13 6279 12 0.0019111 0.9230769 REAC:R-HSA-74217 REAC Purine salvage 10777 1732 REAC:R-H…. query_1 TRUE 0.0307338 13 6279 12 0.0019111 0.9230769 REAC:R-HSA-9637687 REAC Suppression of phagosomal maturation 10777 2232 REAC:R-H…. query_1 TRUE 0.0307338 13 6279 12 0.0019111 0.9230769 REAC:R-HSA-68884 REAC Mitotic Telophase/Cytokinesis 10777 1407 REAC:R-H…. query_1 TRUE 0.0307338 13 6279 12 0.0019111 0.9230769 REAC:R-HSA-9679504 REAC Translation of Replicase and Assembly of the Replication Transcription Complex 10777 2432 REAC:R-H…. query_1 TRUE 0.0307338 13 6279 12 0.0019111 0.9230769 REAC:R-HSA-113501 REAC Inhibition of replication initiation of damaged DNA by RB1/E2F1 10777 1138 REAC:R-H…. query_1 TRUE 0.0307338 13 6279 12 0.0019111 0.9230769 REAC:R-HSA-4419969 REAC Depolymerisation of the Nuclear Lamina 10777 695 REAC:R-H…. query_1 TRUE 0.0307338 13 6279 12 0.0019111 0.9230769 REAC:R-HSA-9694676 REAC Translation of Replicase and Assembly of the Replication Transcription Complex 10777 2433 REAC:R-H…. query_1 TRUE 0.0314385 92 6279 65 0.0103520 0.7065217 REAC:R-HSA-1592230 REAC Mitochondrial biogenesis 10777 1387 REAC:R-H…. query_1 TRUE 0.0323850 27 6279 22 0.0035037 0.8148148 REAC:R-HSA-1614635 REAC Sulfur amino acid metabolism 10777 2227 REAC:R-H…. query_1 TRUE 0.0323850 27 6279 22 0.0035037 0.8148148 REAC:R-HSA-8863795 REAC Downregulation of ERBB2 signaling 10777 746 REAC:R-H…. query_1 TRUE 0.0323850 27 6279 22 0.0035037 0.8148148 REAC:R-HSA-8982491 REAC Glycogen metabolism 10777 1010 REAC:R-H…. query_1 TRUE 0.0349786 66 6279 48 0.0076445 0.7272727 REAC:R-HSA-9614085 REAC FOXO-mediated transcription 10777 877 REAC:R-H…. query_1 TRUE 0.0350669 30 6279 24 0.0038223 0.8000000 REAC:R-HSA-182971 REAC EGFR downregulation 10777 776 REAC:R-H…. query_1 TRUE 0.0355450 20 6279 17 0.0027074 0.8500000 REAC:R-HSA-6803204 REAC TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 10777 2323 REAC:R-H…. query_1 TRUE 0.0355450 20 6279 17 0.0027074 0.8500000 REAC:R-HSA-164938 REAC Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 10777 1480 REAC:R-H…. query_1 TRUE 0.0355450 20 6279 17 0.0027074 0.8500000 REAC:R-HSA-6807004 REAC Negative regulation of MET activity 10777 1489 REAC:R-H…. query_1 TRUE 0.0355450 20 6279 17 0.0027074 0.8500000 REAC:R-HSA-389513 REAC CTLA4 inhibitory signaling 10777 277 REAC:R-H…. query_1 TRUE 0.0381310 36 6279 28 0.0044593 0.7777778 REAC:R-HSA-8964043 REAC Plasma lipoprotein clearance 10777 1667 REAC:R-H…. query_1 TRUE 0.0381310 36 6279 28 0.0044593 0.7777778 REAC:R-HSA-9607240 REAC FLT3 Signaling 10777 871 REAC:R-H…. query_1 TRUE 0.0381446 54 6279 40 0.0063704 0.7407407 REAC:R-HSA-5620924 REAC Intraflagellar transport 10777 1207 REAC:R-H…. query_1 TRUE 0.0409364 269 6279 175 0.0278707 0.6505576 REAC:R-HSA-5684996 REAC MAPK1/MAPK3 signaling 10777 1285 REAC:R-H…. query_1 TRUE 0.0409364 23 6279 19 0.0030260 0.8260870 REAC:R-HSA-8949215 REAC Mitochondrial calcium ion transport 10777 1388 REAC:R-H…. query_1 TRUE 0.0409364 23 6279 19 0.0030260 0.8260870 REAC:R-HSA-5620922 REAC BBSome-mediated cargo-targeting to cilium 10777 192 REAC:R-H…. query_1 TRUE 0.0409364 23 6279 19 0.0030260 0.8260870 REAC:R-HSA-8956321 REAC Nucleotide salvage 10777 1540 REAC:R-H…. query_1 TRUE 0.0423281 16 6279 14 0.0022297 0.8750000 REAC:R-HSA-9614657 REAC FOXO-mediated transcription of cell death genes 10777 879 REAC:R-H…. query_1 TRUE 0.0423281 16 6279 14 0.0022297 0.8750000 REAC:R-HSA-936964 REAC Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 10777 81 REAC:R-H…. query_1 TRUE 0.0423281 16 6279 14 0.0022297 0.8750000 REAC:R-HSA-193639 REAC p75NTR signals via NF-kB 10777 2584 REAC:R-H…. query_1 TRUE 0.0423281 16 6279 14 0.0022297 0.8750000 REAC:R-HSA-3322077 REAC Glycogen synthesis 10777 1019 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-8948700 REAC Competing endogenous RNAs (ceRNAs) regulate PTEN translation 10777 369 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-196783 REAC Coenzyme A biosynthesis 10777 362 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-68952 REAC DNA replication initiation 10777 427 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-73942 REAC DNA Damage Reversal 10777 419 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-3323169 REAC Defects in biotin (Btn) metabolism 10777 680 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-9715370 REAC Miro GTPase Cycle 10777 1378 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-72731 REAC Recycling of eIF2:GDP 10777 1860 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-8951936 REAC RUNX3 regulates p14-ARF 10777 1845 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-75158 REAC TRAIL signaling 10777 2335 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-68689 REAC CDC6 association with the ORC:origin complex 10777 259 REAC:R-H…. query_1 TRUE 0.0424850 8 6279 8 0.0012741 1.0000000 REAC:R-HSA-2142789 REAC Ubiquinol biosynthesis 10777 2480 REAC:R-H…. query_1 TRUE 0.0455618 59 6279 43 0.0068482 0.7288136 REAC:R-HSA-193648 REAC NRAGE signals death through JNK 10777 1463 REAC:R-H…. query_1 TRUE 0.0460783 76 6279 54 0.0086001 0.7105263 REAC:R-HSA-6806834 REAC Signaling by MET 10777 2145 REAC:R-H…. query_1 TRUE 0.0464187 12 6279 11 0.0017519 0.9166667 REAC:R-HSA-6803211 REAC TP53 Regulates Transcription of Death Receptors and Ligands 10777 2322 REAC:R-H…. query_1 TRUE 0.0464187 12 6279 11 0.0017519 0.9166667 REAC:R-HSA-1358803 REAC Downregulation of ERBB2:ERBB3 signaling 10777 747 REAC:R-H…. query_1 TRUE 0.0464187 12 6279 11 0.0017519 0.9166667 REAC:R-HSA-877312 REAC Regulation of IFNG signaling 10777 1880 REAC:R-H…. query_1 TRUE 0.0464187 12 6279 11 0.0017519 0.9166667 REAC:R-HSA-174403 REAC Glutathione synthesis and recycling 10777 1005 REAC:R-H…. query_1 TRUE 0.0464187 12 6279 11 0.0017519 0.9166667 REAC:R-HSA-9013973 REAC TICAM1-dependent activation of IRF3/IRF7 10777 2307 REAC:R-H…. query_1 TRUE 0.0464187 12 6279 11 0.0017519 0.9166667 REAC:R-HSA-9614399 REAC Regulation of localization of FOXO transcription factors 10777 1927 REAC:R-H…. query_1 TRUE 0.0475691 73 6279 52 0.0082816 0.7123288 REAC:R-HSA-9009391 REAC Extra-nuclear estrogen signaling 10777 843 REAC:R-H…. query_1 TRUE 0.0476338 809 6279 501 0.0797898 0.6192831 REAC:R-HSA-1280218 REAC Adaptive Immune System 10777 113 REAC:R-H…. query_1 TRUE 0.0000000 430 4513 347 0.0768890 0.8069767 WP:WP3888 WP VEGFA-VEGFR2 signaling pathway 7899 730 WP:000000 query_1 TRUE 0.0000000 214 4513 188 0.0416574 0.8785047 WP:WP4352 WP Ciliary landscape 7899 488 WP:000000 query_1 TRUE 0.0000000 125 4513 118 0.0261467 0.9440000 WP:WP411 WP mRNA processing 7899 672 WP:000000 query_1 TRUE 0.0000000 119 4513 111 0.0245956 0.9327731 WP:WP4946 WP DNA repair pathways, full network 7899 414 WP:000000 query_1 TRUE 0.0000000 120 4513 110 0.0243740 0.9166667 WP:WP179 WP Cell cycle 7899 207 WP:000000 query_1 TRUE 0.0000000 90 4513 86 0.0190561 0.9555556 WP:WP2446 WP Retinoblastoma gene in cancer 7899 381 WP:000000 query_1 TRUE 0.0000000 161 4513 137 0.0303567 0.8509317 WP:WP437 WP EGF/EGFR signaling pathway 7899 526 WP:000000 query_1 TRUE 0.0000000 131 4513 115 0.0254819 0.8778626 WP:WP366 WP TGF-beta signaling pathway 7899 54 WP:000000 query_1 TRUE 0.0000000 88 4513 82 0.0181697 0.9318182 WP:WP477 WP Cytoplasmic ribosomal proteins 7899 72 WP:000000 query_1 TRUE 0.0000000 81 4513 76 0.0168402 0.9382716 WP:WP4016 WP DNA IR-damage and cellular response via ATR 7899 403 WP:000000 query_1 TRUE 0.0000000 160 4513 133 0.0294704 0.8312500 WP:WP481 WP Insulin signaling 7899 447 WP:000000 query_1 TRUE 0.0000000 114 4513 99 0.0219366 0.8684211 WP:WP4659 WP Gastrin signaling pathway 7899 532 WP:000000 query_1 TRUE 0.0000000 44 4513 44 0.0097496 1.0000000 WP:WP4577 WP Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway 7899 574 WP:000000 query_1 TRUE 0.0000000 55 4513 53 0.0117439 0.9636364 WP:WP3959 WP DNA IR-double strand breaks and cellular response via ATM 7899 25 WP:000000 query_1 TRUE 0.0000000 88 4513 78 0.0172834 0.8863636 WP:WP4263 WP Pancreatic adenocarcinoma pathway 7899 590 WP:000000 query_1 TRUE 0.0000000 92 4513 81 0.0179481 0.8804348 WP:WP231 WP TNF-alpha signaling pathway 7899 641 WP:000000 query_1 TRUE 0.0000000 89 4513 78 0.0172834 0.8764045 WP:WP138 WP Androgen receptor signaling pathway 7899 393 WP:000000 query_1 TRUE 0.0000001 42 4513 41 0.0090849 0.9761905 WP:WP466 WP DNA replication 7899 63 WP:000000 query_1 TRUE 0.0000001 69 4513 62 0.0137381 0.8985507 WP:WP707 WP DNA damage response 7899 552 WP:000000 query_1 TRUE 0.0000001 64 4513 58 0.0128518 0.9062500 WP:WP45 WP G1 to S cell cycle control 7899 586 WP:000000 query_1 TRUE 0.0000001 76 4513 67 0.0148460 0.8815789 WP:WP2034 WP Leptin signaling pathway 7899 459 WP:000000 query_1 TRUE 0.0000001 132 4513 107 0.0237093 0.8106061 WP:WP3915 WP Angiopoietin-like protein 8 regulatory pathway 7899 749 WP:000000 query_1 TRUE 0.0000002 50 4513 47 0.0104144 0.9400000 WP:WP107 WP Translation factors 7899 231 WP:000000 query_1 TRUE 0.0000002 45 4513 43 0.0095280 0.9555556 WP:WP3878 WP ATM signaling in development and disease 7899 461 WP:000000 query_1 TRUE 0.0000003 49 4513 46 0.0101928 0.9387755 WP:WP2637 WP Interleukin-1 (IL-1) structural pathway 7899 594 WP:000000 query_1 TRUE 0.0000004 84 4513 72 0.0159539 0.8571429 WP:WP4022 WP Pyrimidine metabolism 7899 638 WP:000000 query_1 TRUE 0.0000004 65 4513 58 0.0128518 0.8923077 WP:WP2374 WP Oncostatin M signaling pathway 7899 101 WP:000000 query_1 TRUE 0.0000005 76 4513 66 0.0146244 0.8684211 WP:WP4656 WP Joubert syndrome 7899 98 WP:000000 query_1 TRUE 0.0000007 31 4513 31 0.0068690 1.0000000 WP:WP4752 WP Base excision repair 7899 484 WP:000000 query_1 TRUE 0.0000007 42 4513 40 0.0088633 0.9523810 WP:WP4290 WP Metabolic reprogramming in colon cancer 7899 547 WP:000000 query_1 TRUE 0.0000007 42 4513 40 0.0088633 0.9523810 WP:WP5220 WP Metabolic reprogramming in pancreatic cancer 7899 355 WP:000000 query_1 TRUE 0.0000008 71 4513 62 0.0137381 0.8732394 WP:WP1982 WP Sterol regulatory element-binding proteins (SREBP) signaling 7899 206 WP:000000 query_1 TRUE 0.0000009 151 4513 118 0.0261467 0.7814570 WP:WP4666 WP Hepatitis B infection 7899 99 WP:000000 query_1 TRUE 0.0000009 46 4513 43 0.0095280 0.9347826 WP:WP4566 WP Translation inhibitors in chronically activated PDGFRA cells 7899 695 WP:000000 query_1 TRUE 0.0000011 41 4513 39 0.0086417 0.9512195 WP:WP405 WP Eukaryotic transcription initiation 7899 359 WP:000000 query_1 TRUE 0.0000012 66 4513 58 0.0128518 0.8787879 WP:WP2032 WP Thyroid stimulating hormone (TSH) signaling pathway 7899 151 WP:000000 query_1 TRUE 0.0000014 101 4513 83 0.0183913 0.8217822 WP:WP4536 WP Genes related to primary cilium development (based on CRISPR) 7899 642 WP:000000 query_1 TRUE 0.0000016 40 4513 38 0.0084201 0.9500000 WP:WP2516 WP ATM signaling pathway 7899 52 WP:000000 query_1 TRUE 0.0000018 83 4513 70 0.0155107 0.8433735 WP:WP2261 WP Glioblastoma signaling pathways 7899 195 WP:000000 query_1 TRUE 0.0000020 154 4513 119 0.0263683 0.7727273 WP:WP4396 WP Nonalcoholic fatty liver disease 7899 588 WP:000000 query_1 TRUE 0.0000025 64 4513 56 0.0124086 0.8750000 WP:WP4313 WP Ferroptosis 7899 366 WP:000000 query_1 TRUE 0.0000034 43 4513 40 0.0088633 0.9302326 WP:WP4753 WP Nucleotide excision repair 7899 562 WP:000000 query_1 TRUE 0.0000036 74 4513 63 0.0139597 0.8513514 WP:WP4674 WP Head and neck squamous cell carcinoma 7899 598 WP:000000 query_1 TRUE 0.0000040 33 4513 32 0.0070906 0.9696970 WP:WP4880 WP Host-pathogen interaction of human coronaviruses - interferon induction 7899 706 WP:000000 query_1 TRUE 0.0000040 55 4513 49 0.0108575 0.8909091 WP:WP195 WP IL-1 signaling pathway 7899 215 WP:000000 query_1 TRUE 0.0000062 54 4513 48 0.0106359 0.8888889 WP:WP395 WP IL-4 signaling pathway 7899 301 WP:000000 query_1 TRUE 0.0000148 52 4513 46 0.0101928 0.8846154 WP:WP3286 WP Copper homeostasis 7899 97 WP:000000 query_1 TRUE 0.0000180 90 4513 73 0.0161755 0.8111111 WP:WP1772 WP Apoptosis modulation and signaling 7899 658 WP:000000 query_1 TRUE 0.0000180 30 4513 29 0.0064259 0.9666667 WP:WP4923 WP Autophagy 7899 694 WP:000000 query_1 TRUE 0.0000190 73 4513 61 0.0135165 0.8356164 WP:WP4216 WP Chromosomal and microsatellite instability in colorectal cancer 7899 73 WP:000000 query_1 TRUE 0.0000207 96 4513 77 0.0170618 0.8020833 WP:WP4963 WP p53 transcriptional gene network 7899 40 WP:000000 query_1 TRUE 0.0000215 76 4513 63 0.0139597 0.8289474 WP:WP2037 WP Prolactin signaling pathway 7899 529 WP:000000 query_1 TRUE 0.0000215 62 4513 53 0.0117439 0.8548387 WP:WP5180 WP DYRK1A 7899 374 WP:000000 query_1 TRUE 0.0000260 72 4513 60 0.0132949 0.8333333 WP:WP4255 WP Non-small cell lung cancer 7899 668 WP:000000 query_1 TRUE 0.0000277 54 4513 47 0.0104144 0.8703704 WP:WP585 WP Interferon type I signaling pathways 7899 719 WP:000000 query_1 TRUE 0.0000329 23 4513 23 0.0050964 1.0000000 WP:WP531 WP DNA mismatch repair 7899 15 WP:000000 query_1 TRUE 0.0000329 23 4513 23 0.0050964 1.0000000 WP:WP4197 WP Immune response to tuberculosis 7899 84 WP:000000 query_1 TRUE 0.0000339 91 4513 73 0.0161755 0.8021978 WP:WP673 WP ErbB signaling pathway 7899 178 WP:000000 query_1 TRUE 0.0000375 33 4513 31 0.0068690 0.9393939 WP:WP422 WP MAPK cascade 7899 515 WP:000000 query_1 TRUE 0.0000390 53 4513 46 0.0101928 0.8679245 WP:WP2864 WP Apoptosis-related network due to altered Notch3 in ovarian cancer 7899 133 WP:000000 query_1 TRUE 0.0000521 96 4513 76 0.0168402 0.7916667 WP:WP4658 WP Small cell lung cancer 7899 495 WP:000000 query_1 TRUE 0.0000590 32 4513 30 0.0066475 0.9375000 WP:WP3414 WP Initiation of transcription and translation elongation at the HIV-1 LTR 7899 118 WP:000000 query_1 TRUE 0.0000688 36 4513 33 0.0073122 0.9166667 WP:WP4877 WP Host-pathogen interaction of human coronaviruses - MAPK signaling 7899 623 WP:000000 query_1 TRUE 0.0000977 47 4513 41 0.0090849 0.8723404 WP:WP4718 WP Cholesterol metabolism with Bloch and Kandutsch-Russell pathways 7899 200 WP:000000 query_1 TRUE 0.0001382 77 4513 62 0.0137381 0.8051948 WP:WP4949 WP 16p11.2 proximal deletion syndrome 7899 45 WP:000000 query_1 TRUE 0.0001505 30 4513 28 0.0062043 0.9333333 WP:WP3844 WP PI3K-AKT-mTOR signaling pathway and therapeutic opportunities 7899 308 WP:000000 query_1 TRUE 0.0001645 86 4513 68 0.0150676 0.7906977 WP:WP4018 WP Clear cell renal cell carcinoma pathways 7899 203 WP:000000 query_1 TRUE 0.0001752 63 4513 52 0.0115223 0.8253968 WP:WP4155 WP Endometrial cancer 7899 703 WP:000000 query_1 TRUE 0.0001752 25 4513 24 0.0053180 0.9600000 WP:WP4521 WP Glycosylation and related congenital defects 7899 271 WP:000000 query_1 TRUE 0.0002331 29 4513 27 0.0059827 0.9310345 WP:WP3972 WP PDGFR-beta pathway 7899 107 WP:000000 query_1 TRUE 0.0002495 19 4513 19 0.0042101 1.0000000 WP:WP4863 WP Host-pathogen interaction of human coronaviruses - autophagy 7899 462 WP:000000 query_1 TRUE 0.0002661 48 4513 41 0.0090849 0.8541667 WP:WP1971 WP Integrated cancer pathway 7899 35 WP:000000 query_1 TRUE 0.0002719 65 4513 53 0.0117439 0.8153846 WP:WP3651 WP Pathways affected in adenoid cystic carcinoma 7899 39 WP:000000 query_1 TRUE 0.0002756 24 4513 23 0.0050964 0.9583333 WP:WP4686 WP Leucine, isoleucine and valine metabolism 7899 48 WP:000000 query_1 TRUE 0.0002871 84 4513 66 0.0146244 0.7857143 WP:WP4806 WP EGFR tyrosine kinase inhibitor resistance 7899 132 WP:000000 query_1 TRUE 0.0003359 143 4513 105 0.0232661 0.7342657 WP:WP2853 WP Endoderm differentiation 7899 134 WP:000000 query_1 TRUE 0.0003359 40 4513 35 0.0077554 0.8750000 WP:WP2526 WP PDGF pathway 7899 601 WP:000000 query_1 TRUE 0.0003706 47 4513 40 0.0088633 0.8510638 WP:WP1541 WP Energy metabolism 7899 669 WP:000000 query_1 TRUE 0.0003835 18 4513 18 0.0039885 1.0000000 WP:WP3879 WP 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression 7899 89 WP:000000 query_1 TRUE 0.0003835 18 4513 18 0.0039885 1.0000000 WP:WP4533 WP Transcription co-factors SKI and SKIL protein partners 7899 125 WP:000000 query_1 TRUE 0.0003835 18 4513 18 0.0039885 1.0000000 WP:WP78 WP TCA cycle (aka Krebs or citric acid cycle) 7899 51 WP:000000 query_1 TRUE 0.0003966 57 4513 47 0.0104144 0.8245614 WP:WP4879 WP Overlap between signal transduction pathways contributing to LMNA laminopathies 7899 464 WP:000000 query_1 TRUE 0.0003966 110 4513 83 0.0183913 0.7545455 WP:WP710 WP DNA damage response (only ATM dependent) 7899 430 WP:000000 query_1 TRUE 0.0004057 43 4513 37 0.0081985 0.8604651 WP:WP314 WP Fas ligand pathway and stress induction of heat shock proteins 7899 431 WP:000000 query_1 TRUE 0.0004057 23 4513 22 0.0048748 0.9565217 WP:WP4357 WP NRF2-ARE regulation 7899 128 WP:000000 query_1 TRUE 0.0005168 97 4513 74 0.0163971 0.7628866 WP:WP23 WP B cell receptor signaling pathway 7899 517 WP:000000 query_1 TRUE 0.0005168 66 4513 53 0.0117439 0.8030303 WP:WP2324 WP AGE/RAGE pathway 7899 700 WP:000000 query_1 TRUE 0.0006564 22 4513 21 0.0046532 0.9545455 WP:WP357 WP Fatty acid biosynthesis 7899 452 WP:000000 query_1 TRUE 0.0006623 62 4513 50 0.0110791 0.8064516 WP:WP183 WP Proteasome degradation 7899 105 WP:000000 query_1 TRUE 0.0006638 87 4513 67 0.0148460 0.7701149 WP:WP254 WP Apoptosis 7899 583 WP:000000 query_1 TRUE 0.0007399 55 4513 45 0.0099712 0.8181818 WP:WP2018 WP RANKL/RANK signaling pathway 7899 675 WP:000000 query_1 TRUE 0.0007399 34 4513 30 0.0066475 0.8823529 WP:WP313 WP Hepatocyte growth factor receptor signaling 7899 472 WP:000000 query_1 TRUE 0.0007399 34 4513 30 0.0066475 0.8823529 WP:WP400 WP p38 MAPK signaling pathway 7899 66 WP:000000 query_1 TRUE 0.0007399 68 4513 54 0.0119654 0.7941176 WP:WP3303 WP RAC1/PAK1/p38/MMP2 pathway 7899 519 WP:000000 query_1 TRUE 0.0010048 16 4513 16 0.0035453 1.0000000 WP:WP2916 WP Interactome of polycomb repressive complex 2 (PRC2) 7899 4 WP:000000 query_1 TRUE 0.0010129 44 4513 37 0.0081985 0.8409091 WP:WP2332 WP Interleukin-11 signaling pathway 7899 22 WP:000000 query_1 TRUE 0.0011138 33 4513 29 0.0064259 0.8787879 WP:WP244 WP Alpha 6 beta 4 signaling pathway 7899 267 WP:000000 query_1 TRUE 0.0012213 60 4513 48 0.0106359 0.8000000 WP:WP3865 WP Novel intracellular components of RIG-I-like receptor pathway 7899 750 WP:000000 query_1 TRUE 0.0015988 56 4513 45 0.0099712 0.8035714 WP:WP4324 WP Mitochondrial complex I assembly model OXPHOS system 7899 634 WP:000000 query_1 TRUE 0.0016236 20 4513 19 0.0042101 0.9500000 WP:WP4206 WP Hereditary leiomyomatosis and renal cell carcinoma pathway 7899 321 WP:000000 query_1 TRUE 0.0016460 59 4513 47 0.0104144 0.7966102 WP:WP304 WP Kit receptor signaling pathway 7899 702 WP:000000 query_1 TRUE 0.0016460 59 4513 47 0.0104144 0.7966102 WP:WP61 WP Notch signaling pathway 7899 172 WP:000000 query_1 TRUE 0.0016460 15 4513 15 0.0033237 1.0000000 WP:WP197 WP Cholesterol biosynthesis pathway 7899 157 WP:000000 query_1 TRUE 0.0016460 144 4513 103 0.0228230 0.7152778 WP:WP2380 WP Brain-derived neurotrophic factor (BDNF) signaling pathway 7899 425 WP:000000 query_1 TRUE 0.0018015 260 4513 176 0.0389984 0.6769231 WP:WP5124 WP Alzheimer’s disease 7899 77 WP:000000 query_1 TRUE 0.0027279 108 4513 79 0.0175050 0.7314815 WP:WP4321 WP Thermogenesis 7899 96 WP:000000 query_1 TRUE 0.0027279 27 4513 24 0.0053180 0.8888889 WP:WP3613 WP Photodynamic therapy-induced unfolded protein response 7899 693 WP:000000 query_1 TRUE 0.0027853 23 4513 21 0.0046532 0.9130435 WP:WP2509 WP Nanoparticle triggered autophagic cell death 7899 689 WP:000000 query_1 TRUE 0.0027853 23 4513 21 0.0046532 0.9130435 WP:WP4537 WP Hippo-Yap signaling pathway 7899 402 WP:000000 query_1 TRUE 0.0030210 34 4513 29 0.0064259 0.8529412 WP:WP4922 WP Mitochondrial complex IV assembly 7899 549 WP:000000 query_1 TRUE 0.0038318 50 4513 40 0.0088633 0.8000000 WP:WP3611 WP Photodynamic therapy-induced AP-1 survival signaling 7899 629 WP:000000 query_1 TRUE 0.0040013 18 4513 17 0.0037669 0.9444444 WP:WP4936 WP Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins 7899 228 WP:000000 query_1 TRUE 0.0040013 18 4513 17 0.0037669 0.9444444 WP:WP5193 WP Cholesterol synthesis disorders 7899 294 WP:000000 query_1 TRUE 0.0040684 40 4513 33 0.0073122 0.8250000 WP:WP127 WP IL-5 signaling pathway 7899 335 WP:000000 query_1 TRUE 0.0042500 22 4513 20 0.0044316 0.9090909 WP:WP4482 WP Vitamin D in inflammatory diseases 7899 650 WP:000000 query_1 TRUE 0.0044301 13 4513 13 0.0028806 1.0000000 WP:WP4190 WP Mevalonate arm of cholesterol biosynthesis pathway 7899 44 WP:000000 query_1 TRUE 0.0044320 43 4513 35 0.0077554 0.8139535 WP:WP364 WP IL6 signaling pathway 7899 138 WP:000000 query_1 TRUE 0.0047884 46 4513 37 0.0081985 0.8043478 WP:WP4535 WP Envelope proteins and their potential roles in EDMD physiopathology 7899 499 WP:000000 query_1 TRUE 0.0049603 36 4513 30 0.0066475 0.8333333 WP:WP1471 WP Target of rapamycin signaling 7899 765 WP:000000 query_1 TRUE 0.0049603 36 4513 30 0.0066475 0.8333333 WP:WP3850 WP Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling 7899 95 WP:000000 query_1 TRUE 0.0055415 73 4513 55 0.0121870 0.7534247 WP:WP5114 WP Nucleotide excision repair in xeroderma pigmentosum 7899 291 WP:000000 query_1 TRUE 0.0055415 58 4513 45 0.0099712 0.7758621 WP:WP4205 WP MET in type 1 papillary renal cell carcinoma 7899 14 WP:000000 query_1 TRUE 0.0058196 25 4513 22 0.0048748 0.8800000 WP:WP205 WP IL-7 signaling pathway 7899 627 WP:000000 query_1 TRUE 0.0060120 42 4513 34 0.0075338 0.8095238 WP:WP2036 WP TNF-related weak inducer of apoptosis (TWEAK) signaling pathway 7899 626 WP:000000 query_1 TRUE 0.0060120 17 4513 16 0.0035453 0.9411765 WP:WP368 WP Mitochondrial long chain fatty acid beta-oxidation 7899 87 WP:000000 query_1 TRUE 0.0071467 12 4513 12 0.0026590 1.0000000 WP:WP3849 WP MAPK and NFkB signaling pathways inhibited by Yersinia YopJ 7899 433 WP:000000 query_1 TRUE 0.0072792 28 4513 24 0.0053180 0.8571429 WP:WP2643 WP Nanoparticle-mediated activation of receptor signaling 7899 276 WP:000000 query_1 TRUE 0.0072792 28 4513 24 0.0053180 0.8571429 WP:WP3851 WP TLR4 signaling and tolerance 7899 23 WP:000000 query_1 TRUE 0.0085879 31 4513 26 0.0057611 0.8387097 WP:WP3996 WP Ethanol effects on histone modifications 7899 49 WP:000000 query_1 TRUE 0.0085879 24 4513 21 0.0046532 0.8750000 WP:WP4925 WP Unfolded protein response 7899 453 WP:000000 query_1 TRUE 0.0085879 31 4513 26 0.0057611 0.8387097 WP:WP4868 WP Type I interferon induction and signaling during SARS-CoV-2 infection 7899 326 WP:000000 query_1 TRUE 0.0090232 71 4513 53 0.0117439 0.7464789 WP:WP2359 WP Parkin-ubiquitin proteasomal system pathway 7899 720 WP:000000 query_1 TRUE 0.0090232 91 4513 66 0.0146244 0.7252747 WP:WP3925 WP Amino acid metabolism 7899 676 WP:000000 query_1 TRUE 0.0090232 16 4513 15 0.0033237 0.9375000 WP:WP4921 WP Mitochondrial complex III assembly 7899 711 WP:000000 query_1 TRUE 0.0090232 68 4513 51 0.0113007 0.7500000 WP:WP4685 WP Melanoma 7899 177 WP:000000 query_1 TRUE 0.0090232 16 4513 15 0.0033237 0.9375000 WP:WP5027 WP nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell 7899 137 WP:000000 query_1 TRUE 0.0090232 16 4513 15 0.0033237 0.9375000 WP:WP2453 WP TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc) 7899 92 WP:000000 query_1 TRUE 0.0090232 436 4513 279 0.0618214 0.6399083 WP:WP5087 WP Malignant pleural mesothelioma 7899 714 WP:000000 query_1 TRUE 0.0092168 34 4513 28 0.0062043 0.8235294 WP:WP5117 WP Cohesin complex - Cornelia de Lange syndrome 7899 56 WP:000000 query_1 TRUE 0.0092168 34 4513 28 0.0062043 0.8235294 WP:WP4241 WP Type 2 papillary renal cell carcinoma 7899 600 WP:000000 query_1 TRUE 0.0101162 37 4513 30 0.0066475 0.8108108 WP:WP3614 WP Photodynamic therapy-induced HIF-1 survival signaling 7899 26 WP:000000 query_1 TRUE 0.0110332 11 4513 11 0.0024374 1.0000000 WP:WP5049 WP Glycolysis in senescence 7899 455 WP:000000 query_1 TRUE 0.0110332 11 4513 11 0.0024374 1.0000000 WP:WP5118 WP SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome 7899 386 WP:000000 query_1 TRUE 0.0111068 70 4513 52 0.0115223 0.7428571 WP:WP2880 WP Glucocorticoid receptor pathway 7899 566 WP:000000 query_1 TRUE 0.0113127 67 4513 50 0.0110791 0.7462687 WP:WP1403 WP AMP-activated protein kinase signaling 7899 551 WP:000000 query_1 TRUE 0.0113806 30 4513 25 0.0055396 0.8333333 WP:WP1422 WP Sphingolipid pathway 7899 436 WP:000000 query_1 TRUE 0.0113806 46 4513 36 0.0079770 0.7826087 WP:WP4861 WP Endoplasmic reticulum stress response in coronavirus infection 7899 193 WP:000000 query_1 TRUE 0.0113996 55 4513 42 0.0093064 0.7636364 WP:WP2795 WP Cardiac hypertrophic response 7899 662 WP:000000 query_1 TRUE 0.0113996 23 4513 20 0.0044316 0.8695652 WP:WP3612 WP Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling 7899 305 WP:000000 query_1 TRUE 0.0113996 23 4513 20 0.0044316 0.8695652 WP:WP262 WP Ebstein-Barr virus LMP1 signaling 7899 106 WP:000000 query_1 TRUE 0.0113996 55 4513 42 0.0093064 0.7636364 WP:WP2272 WP Pathogenic Escherichia coli infection 7899 535 WP:000000 query_1 TRUE 0.0113996 49 4513 38 0.0084201 0.7755102 WP:WP286 WP IL-3 signaling pathway 7899 241 WP:000000 query_1 TRUE 0.0114391 273 4513 179 0.0396632 0.6556777 WP:WP4754 WP IL-18 signaling pathway 7899 361 WP:000000 query_1 TRUE 0.0120936 128 4513 89 0.0197208 0.6953125 WP:WP4217 WP Ebola virus infection in host 7899 738 WP:000000 query_1 TRUE 0.0130968 15 4513 14 0.0031021 0.9333333 WP:WP4240 WP Regulation of sister chromatid separation at the metaphase-anaphase transition 7899 458 WP:000000 query_1 TRUE 0.0130968 15 4513 14 0.0031021 0.9333333 WP:WP5182 WP Pro-survival signaling of neuroprotectin D1 7899 585 WP:000000 query_1 TRUE 0.0130968 15 4513 14 0.0031021 0.9333333 WP:WP3 WP Transcriptional activation by NRF2 in response to phytochemicals 7899 108 WP:000000 query_1 TRUE 0.0135022 26 4513 22 0.0048748 0.8461538 WP:WP581 WP EPO receptor signaling 7899 568 WP:000000 query_1 TRUE 0.0136918 66 4513 49 0.0108575 0.7424242 WP:WP3680 WP Physico-chemical features and toxicity-associated pathways 7899 575 WP:000000 query_1 TRUE 0.0141809 42 4513 33 0.0073122 0.7857143 WP:WP49 WP IL-2 signaling pathway 7899 474 WP:000000 query_1 TRUE 0.0153502 29 4513 24 0.0053180 0.8275862 WP:WP3965 WP Lipid metabolism pathway 7899 314 WP:000000 query_1 TRUE 0.0162718 22 4513 19 0.0042101 0.8636364 WP:WP4224 WP Purine metabolism and related disorders 7899 611 WP:000000 query_1 TRUE 0.0162718 22 4513 19 0.0042101 0.8636364 WP:WP3580 WP Methionine de novo and salvage pathway 7899 587 WP:000000 query_1 TRUE 0.0163557 10 4513 10 0.0022158 1.0000000 WP:WP5050 WP TCA cycle in senescence 7899 224 WP:000000 query_1 TRUE 0.0163557 32 4513 26 0.0057611 0.8125000 WP:WP2112 WP IL-17 signaling pathway 7899 724 WP:000000 query_1 TRUE 0.0163557 10 4513 10 0.0022158 1.0000000 WP:WP438 WP Non-homologous end joining 7899 584 WP:000000 query_1 TRUE 0.0163557 32 4513 26 0.0057611 0.8125000 WP:WP5202 WP Alstrom syndrome 7899 262 WP:000000 query_1 TRUE 0.0163557 32 4513 26 0.0057611 0.8125000 WP:WP2363 WP Gastric cancer network 2 7899 122 WP:000000 query_1 TRUE 0.0163557 10 4513 10 0.0022158 1.0000000 WP:WP2333 WP Trans-sulfuration pathway 7899 439 WP:000000 query_1 TRUE 0.0183995 18 4513 16 0.0035453 0.8888889 WP:WP4301 WP Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells 7899 313 WP:000000 query_1 TRUE 0.0183995 18 4513 16 0.0035453 0.8888889 WP:WP2011 WP SREBF and miR33 in cholesterol and lipid homeostasis 7899 148 WP:000000 query_1 TRUE 0.0185845 101 4513 71 0.0157323 0.7029703 WP:WP185 WP Integrin-mediated cell adhesion 7899 43 WP:000000 query_1 TRUE 0.0234600 21 4513 18 0.0039885 0.8571429 WP:WP4864 WP Host-pathogen interaction of human coronaviruses - apoptosis 7899 523 WP:000000 query_1 TRUE 0.0250130 49 4513 37 0.0081985 0.7551020 WP:WP4971 WP Phosphoinositides metabolism 7899 678 WP:000000 query_1 TRUE 0.0275120 9 4513 9 0.0019942 1.0000000 WP:WP4940 WP 15q11.2 copy number variation syndrome 7899 631 WP:000000 query_1 TRUE 0.0275120 9 4513 9 0.0019942 1.0000000 WP:WP5031 WP Biotin metabolism, including IMDs 7899 581 WP:000000 query_1 TRUE 0.0279548 17 4513 15 0.0033237 0.8823529 WP:WP3874 WP Canonical and non-canonical TGF-B signaling 7899 53 WP:000000 query_1 TRUE 0.0299418 152 4513 102 0.0226014 0.6710526 WP:WP2857 WP Mesodermal commitment pathway 7899 221 WP:000000 query_1 TRUE 0.0306052 54 4513 40 0.0088633 0.7407407 WP:WP5144 WP NRP1-triggered signaling pathways in pancreatic cancer 7899 543 WP:000000 query_1 TRUE 0.0306052 13 4513 12 0.0026590 0.9230769 WP:WP4792 WP Purine metabolism 7899 71 WP:000000 query_1 TRUE 0.0306052 13 4513 12 0.0026590 0.9230769 WP:WP186 WP Homologous recombination 7899 747 WP:000000 query_1 TRUE 0.0311446 30 4513 24 0.0053180 0.8000000 WP:WP2870 WP Extracellular vesicle-mediated signaling in recipient cells 7899 201 WP:000000 query_1 TRUE 0.0311886 51 4513 38 0.0084201 0.7450980 WP:WP363 WP Wnt signaling pathway 7899 388 WP:000000 query_1 TRUE 0.0318257 48 4513 36 0.0079770 0.7500000 WP:WP410 WP Exercise-induced circadian regulation 7899 691 WP:000000 query_1 TRUE 0.0333550 20 4513 17 0.0037669 0.8500000 WP:WP2507 WP Nanomaterial induced apoptosis 7899 103 WP:000000 query_1 TRUE 0.0342823 87 4513 61 0.0135165 0.7011494 WP:WP5234 WP Bardet-Biedl syndrome 7899 734 WP:000000 query_1 TRUE 0.0361067 73 4513 52 0.0115223 0.7123288 WP:WP4341 WP Non-genomic actions of 1,25 dihydroxyvitamin D3 7899 716 WP:000000 query_1 TRUE 0.0373862 23 4513 19 0.0042101 0.8260870 WP:WP4725 WP Sphingolipid metabolism overview 7899 265 WP:000000 query_1 TRUE 0.0373862 23 4513 19 0.0042101 0.8260870 WP:WP712 WP Estrogen signaling pathway 7899 261 WP:000000 query_1 TRUE 0.0375883 197 4513 129 0.0285841 0.6548223 WP:WP306 WP Focal adhesion 7899 16 WP:000000 query_1 TRUE 0.0402256 26 4513 21 0.0046532 0.8076923 WP:WP4726 WP Sphingolipid metabolism: integrated pathway 7899 12 WP:000000 query_1 TRUE 0.0402767 16 4513 14 0.0031021 0.8750000 WP:WP4928 WP MAPK pathway in congenital thyroid cancer 7899 527 WP:000000 query_1 TRUE 0.0414099 29 4513 23 0.0050964 0.7931034 WP:WP241 WP One-carbon metabolism 7899 569 WP:000000 query_1 TRUE 0.0414099 44 4513 33 0.0073122 0.7500000 WP:WP268 WP Notch signaling 7899 324 WP:000000 query_1 TRUE 0.0414099 44 4513 33 0.0073122 0.7500000 WP:WP5085 WP Vasopressin-regulated water reabsorption 7899 480 WP:000000 query_1 TRUE 0.0426205 8 4513 8 0.0017727 1.0000000 WP:WP4562 WP Canonical NF-kB pathway 7899 635 WP:000000 query_1 TRUE 0.0426205 8 4513 8 0.0017727 1.0000000 WP:WP5211 WP Glucose metabolism in triple-negative breast cancer cells 7899 263 WP:000000 query_1 TRUE 0.0426205 8 4513 8 0.0017727 1.0000000 WP:WP5179 WP Biosynthesis and turnover of 1-deoxy-sphingoid bases 7899 416 WP:000000 query_1 TRUE 0.0426205 8 4513 8 0.0017727 1.0000000 WP:WP4742 WP Ketogenesis and ketolysis 7899 640 WP:000000 query_1 TRUE 0.0429141 72 4513 51 0.0113007 0.7083333 WP:WP2572 WP Primary focal segmental glomerulosclerosis (FSGS) 7899 81 WP:000000 query_1 TRUE 0.0444955 12 4513 11 0.0024374 0.9166667 WP:WP1425 WP Bone morphogenic protein signaling and regulation 7899 663 WP:000000 query_1 TRUE 0.0444955 12 4513 11 0.0024374 0.9166667 WP:WP4629 WP Aerobic glycolysis 7899 167 WP:000000 query_1 TRUE 0.0444955 80 4513 56 0.0124086 0.7000000 WP:WP5205 WP Clock-controlled autophagy in bone metabolism 7899 260 WP:000000 query_1 TRUE 0.0450053 19 4513 16 0.0035453 0.8421053 WP:WP734 WP Serotonin receptor 4/6/7 and NR3C signaling 7899 737 WP:000000 query_1 TRUE 0.0450053 19 4513 16 0.0035453 0.8421053 WP:WP384 WP Apoptosis modulation by HSP70 7899 155 WP:000000 query_1 TRUE 0.0450053 55 4513 40 0.0088633 0.7272727 WP:WP560 WP TGF-beta receptor signaling 7899 456 WP:000000 query_1 TRUE 0.0450053 19 4513 16 0.0035453 0.8421053 WP:WP391 WP Mitochondrial gene expression 7899 80 WP:000000 query_1 TRUE 0.0462621 66 4513 47 0.0104144 0.7121212 WP:WP2525 WP Trans-sulfuration, one-carbon metabolism and related pathways 7899 109 WP:000000 query_1 TRUE 0.0493573 22 4513 18 0.0039885 0.8181818 WP:WP3645 WP NAD+ biosynthetic pathways 7899 633 WP:000000 query_1 TRUE 0.0493573 46 4513 34 0.0075338 0.7391304 WP:WP4534 WP Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms 7899 609 WP:000000 query_1 TRUE 0.0493573 46 4513 34 0.0075338 0.7391304 WP:WP2038 WP Microtubule cytoskeleton regulation 7899 256 WP:000000

Continuing

gprofiler2::gostplot(Complete_Gprofiler_Analyses) %>% plotly::layout(title = "Complete plot plot", font = list(size = 10))

Part 20:Interpretation

Do the over-representation results support conclusions or mechanism discussed in the original paper ?

Yes the over-representation results we find is correlated to the conclusion the authors make. They conclude that genes having higher GLI2 expression, more differentially expressed, are more possible to be EMT genes. Additionally, we found there is always higher expression on GLI2 treatments given this is a strong oncogene acting in basal-sub-type switching triggering EMT switching. As it is obvious from the visualization the upregualted genes are more clustered and are much more in the downregualted genes This supports the hypothesis of authors, concluding the EMT genes to be higher expression than that of the downregualted genes.

Can you find evidence, i.e. publications, to support some of the results that you see. How does this evidence support your results ?

The paper (Pasca di Magliano et al.,2006) has already indicated increase expression of GLI2 can lead to SHH gene reduction. This gene has been known to be an oncogene associated with basal-sub-type switching in PDAC. They activate GLI2 constantly which has the same expected outcome in our data set having GLI2 expressing vectors with constant Dox treatment. In conclusion these two paper findings correlate each other. They show that the EMT genes to be abundant in their biological functions and their pathway invovlement.

References

Adams, Christina R, Htet Htwe Htwe, Timothy Marsh, Aprilgate L Wang, Megan L Montoya, Lakshmipriya Subbaraj, Aaron D Tward, Nabeel Bardeesy, and Rushika M Perera. 2019. “Transcriptional Control of Subtype Switching Ensures Adaptation and Growth of Pancreatic Cancer.” Elife 8: e45313.

Allaire, JJ, Yihui Xie, Jonathan McPherson, Javier Luraschi, Kevin Ushey, Aron Atkins, Hadley Wickham, Joe Cheng, Winston Chang, and Richard Iannone. 2021. rmarkdown: Dynamic Documents for R. https://github.com/rstudio/rmarkdown.

Davis, S., and P. Meltzer. 2007. “GEOquery: A Bridge Between the Gene Expression Omnibus (GEO) and BioConductor.” Bioinformatics 14: 1846–47.

Durinck, S., P. Spellman, E. Birney, and W. Huber. 2009. “Mapping Identifiers for the Integration of Genomic Datasets with the r/Bioconductor Package biomaRt.” Nature Protocols 4: 1184–91.

Gu, Zuguang. 2022. “Complex Heatmap Visualization.” iMeta 1 (3): e43.

Gu, Zuguang, Lei Gu, Roland Eils, Matthias Schlesner, and Benedikt Brors. 2014. “Circlize Implements and Enhances Circular Visualization in r.” Bioinformatics 30 (19): 2811–12.

Magliano, Marina Pasca di, Shigeki Sekine, Alexandre Ermilov, Jenny Ferris, Andrzej A Dlugosz, and Matthias Hebrok. 2006. “Hedgehog/Ras Interactions Regulate Early Stages of Pancreatic Cancer.” Genes & Development 20 (22): 3161–73.

R Core Team. 2022. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing. https://www.R-project.org/.

Ritchie, Matthew E, Belinda Phipson, DI Wu, Yifang Hu, Charity W Law, Wei Shi, and Gordon K Smyth. 2015. “Limma Powers Differential Expression Analyses for RNA-Sequencing and Microarray Studies.” Nucleic Acids Research 43 (7): e47–47.

Robinson, M. D., McCarthy DJ, and G. K. Smyth. 2010. “edgeR: A Bioconductor Package for Differential Expression Analysis of Digital Gene Expression Data.” Bioinformatics 26: 139–40.